Eli O Meltzer

Summary

Publications

  1. doi request reprint Findings from an Online Survey Assessing the Burden and Management of Seasonal Allergic Rhinoconjunctivitis in US Patients
    Eli O Meltzer
    Division of Immunology and Allergy, Department of Pediatrics, University of California San Diego School of Medicine, and Allergy and Asthma Medical Group and Research Center, San Diego, Calif Electronic address
    J Allergy Clin Immunol Pract . 2016
  2. doi request reprint Minimal Clinically Important Difference (MCID) in Allergic Rhinitis: Agency for Healthcare Research and Quality or Anchor-Based Thresholds?
    Eli O Meltzer
    Division of Immunology and Allergy, Department of Pediatrics, University of California San Diego School of Medicine, San Diego, Calif Allergy and Asthma Medical Group and Research Center, San Diego, Calif Electronic address
    J Allergy Clin Immunol Pract 4:682-688.e6. 2016
  3. doi request reprint Allergic Rhinitis: Burden of Illness, Quality of Life, Comorbidities, and Control
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA Electronic address
    Immunol Allergy Clin North Am 36:235-48. 2016
  4. doi request reprint Roflumilast for asthma: Efficacy findings in placebo-controlled studies
    E O Meltzer
    Department of Pediatrics, Division of Allergy and Immunology, University of California, San Diego, CA, USA Electronic address
    Pulm Pharmacol Ther 35:S20-7. 2015
  5. doi request reprint Efficacy and safety of budesonide administered by pressurized metered-dose inhaler in children with asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California Electronic address
    Ann Allergy Asthma Immunol 115:516-22. 2015
  6. ncbi request reprint Rhinosinusitis: developing guidance for clinical trials
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center and Department of Pediatrics, University of California, San Diego, USA
    J Allergy Clin Immunol 118:S17-61. 2006
  7. doi request reprint Comparison of patient preference for sensory attributes of fluticasone furoate or fluticasone propionate in adults with seasonal allergic rhinitis: a randomized, placebo-controlled, double-blind study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 104:331-8. 2010
  8. ncbi request reprint Rhinosinusitis: establishing definitions for clinical research and patient care
    Eli O Meltzer
    Department of Pediatrics, Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    J Allergy Clin Immunol 114:155-212. 2004
  9. ncbi request reprint Rhinosinusitis: Developing guidance for clinical trials
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center Department of Pediatrics, University of California, San Diego, San Diego, California
    Otolaryngol Head Neck Surg 135:S31-80. 2006
  10. doi request reprint Physician perceptions of the treatment and management of allergic and nonallergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 30:75-83. 2009

Detail Information

Publications63

  1. doi request reprint Findings from an Online Survey Assessing the Burden and Management of Seasonal Allergic Rhinoconjunctivitis in US Patients
    Eli O Meltzer
    Division of Immunology and Allergy, Department of Pediatrics, University of California San Diego School of Medicine, and Allergy and Asthma Medical Group and Research Center, San Diego, Calif Electronic address
    J Allergy Clin Immunol Pract . 2016
    ..Telephone and in-office surveys have demonstrated negative effects of allergic rhinitis (AR) symptoms on sleep, daily activities, productivity, concentration, and emotions...
  2. doi request reprint Minimal Clinically Important Difference (MCID) in Allergic Rhinitis: Agency for Healthcare Research and Quality or Anchor-Based Thresholds?
    Eli O Meltzer
    Division of Immunology and Allergy, Department of Pediatrics, University of California San Diego School of Medicine, San Diego, Calif Allergy and Asthma Medical Group and Research Center, San Diego, Calif Electronic address
    J Allergy Clin Immunol Pract 4:682-688.e6. 2016
    ..Applying this threshold, their data showed no differences between well-established treatments, and a subsequent analysis using prescribing information found no differences between active treatments and placebo controls...
  3. doi request reprint Allergic Rhinitis: Burden of Illness, Quality of Life, Comorbidities, and Control
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA Electronic address
    Immunol Allergy Clin North Am 36:235-48. 2016
    ..The disease burden suffered by patients includes the morbidity of the nasal symptoms, the impairment of multiple domains of quality of life, and numerous comorbidities. The goal of therapy is long-term good control. ..
  4. doi request reprint Roflumilast for asthma: Efficacy findings in placebo-controlled studies
    E O Meltzer
    Department of Pediatrics, Division of Allergy and Immunology, University of California, San Diego, CA, USA Electronic address
    Pulm Pharmacol Ther 35:S20-7. 2015
    ..The role of roflumilast as a potential asthma treatment is not yet fully understood. A series of placebo-controlled trials were undertaken in order to investigate the safety and efficacy of roflumilast in asthma...
  5. doi request reprint Efficacy and safety of budesonide administered by pressurized metered-dose inhaler in children with asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California Electronic address
    Ann Allergy Asthma Immunol 115:516-22. 2015
    ..Budesonide is approved for delivery using a nebulized solution and dry-powder inhaler, but its use through a pressurized metered-dose inhaler (pMDI) in pediatric patients with asthma has not been determined...
  6. ncbi request reprint Rhinosinusitis: developing guidance for clinical trials
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center and Department of Pediatrics, University of California, San Diego, USA
    J Allergy Clin Immunol 118:S17-61. 2006
    ....
  7. doi request reprint Comparison of patient preference for sensory attributes of fluticasone furoate or fluticasone propionate in adults with seasonal allergic rhinitis: a randomized, placebo-controlled, double-blind study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 104:331-8. 2010
    ..Intranasal corticosteroids are first-line treatment for moderate-to-severe seasonal allergic rhinitis (AR)...
  8. ncbi request reprint Rhinosinusitis: establishing definitions for clinical research and patient care
    Eli O Meltzer
    Department of Pediatrics, Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    J Allergy Clin Immunol 114:155-212. 2004
  9. ncbi request reprint Rhinosinusitis: Developing guidance for clinical trials
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center Department of Pediatrics, University of California, San Diego, San Diego, California
    Otolaryngol Head Neck Surg 135:S31-80. 2006
    ....
  10. doi request reprint Physician perceptions of the treatment and management of allergic and nonallergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 30:75-83. 2009
    ..This physician survey provides insight into perceptions of the impact of allergic rhinitis and nonallergic rhinitis on patients' quality of life and symptom severity...
  11. doi request reprint Safety and efficacy of olopatadine hydrochloride nasal spray 0.6% in pediatric subjects with allergic rhinitis
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
    Allergy Asthma Proc 30:612-23. 2009
    ..In subjects 6 to <12 years of age, OLO was superior to vehicle in the treatment of SAR. In subjects 2 to <12 years of age, OLO had an overall low rate of AEs and low systemic exposure...
  12. doi request reprint Comparative study of sensory attributes of two antihistamine nasal sprays: olopatadine 0.6% and azelastine 0.1%
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Allergy Asthma Proc 29:659-68. 2008
    ..This outcome could lead to greater patient compliance and improved treatment effect...
  13. ncbi request reprint Development of questionnaires to measure patient preferences for intranasal corticosteroids in patients with allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Otolaryngol Head Neck Surg 132:197-207. 2005
    ..To develop a questionnaire to evaluate preferences for attributes of intranasal corticosteroids (INSs) in clinical trials with allergic rhinitis (AR) patients...
  14. pmc Rhinosinusitis diagnosis and management for the clinician: a synopsis of recent consensus guidelines
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr, Ste B, San Diego, CA 92123, USA
    Mayo Clin Proc 86:427-43. 2011
    ..Important and relevant data from MEDLINE-indexed articles published since the most recent guidelines were issued are also considered, and needs for future research are discussed...
  15. doi request reprint Mometasone furoate nasal spray increases the number of minimal-symptom days in patients with acute rhinosinusitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 108:275-9. 2012
    ..Acute rhinosinusitis (ARS) is triggered by viral or, uncommonly, bacterial infection, causing inflammatory symptoms for ≤12 weeks...
  16. ncbi request reprint Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 95:600-6. 2005
    ..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR)...
  17. ncbi request reprint Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, University of California at San Diego, San Diego, California, USA
    Allergy Asthma Proc 28:67-73. 2007
    ..Fexofenadine HCl, 180 mg, was superior to desloratadine, 5 mg, in histamine-induced wheal-and-flare suppression, suggesting increased in vivo H1-receptor antagonist potency of fexofenadine versus desloratadine...
  18. ncbi request reprint A preference evaluation study comparing the sensory attributes of mometasone furoate and fluticasone propionate nasal sprays by patients with allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Treat Respir Med 4:289-96. 2005
    ....
  19. ncbi request reprint The systemic safety of inhaled corticosteroid therapy: a focus on ciclesonide
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 97:149-57. 2006
    ..To review the potential systemic activity of ciclesonide and its active metabolite, desisobutyryl-ciclesonide, by evaluation of the effects on hypothalamic-pituitary-adrenal (HPA) axis function...
  20. doi request reprint Burden of allergic rhinitis: allergies in America, Latin America, and Asia-Pacific adult surveys
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA
    Allergy Asthma Proc 33:S113-41. 2012
    ..These findings support the assertion that AR burden has been substantially underestimated and identify several important challenges to successful management of AR...
  21. doi request reprint Safety and tolerability of fluticasone furoate nasal spray once daily in paediatric patients aged 6-11 years with allergic rhinitis: subanalysis of three randomized, double-blind, placebo-controlled, multicentre studies
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Clin Drug Investig 29:79-86. 2009
    ....
  22. doi request reprint Efficacy and safety evaluation of ciclesonide in mild-to-moderate persistent asthma previously treated with inhaled corticosteroids
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 30:293-303. 2009
    ..i.d. maintained asthma control in subjects with stable mild-to-moderate asthma previously treated with ICS or ICS/LABA, was well tolerated, and, in general, was better than CIC160 q.d. in maintaining disease control...
  23. doi request reprint Reliability, validity, and responsiveness of the Rhinitis Control Assessment Test in patients with rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, Calif, USA
    J Allergy Clin Immunol 131:379-86. 2013
    ..The Rhinitis Control Assessment Test (RCAT) is a brief, patient-completed tool to evaluate rhinitis symptom control...
  24. doi request reprint Mometasone furoate nasal spray plus oxymetazoline nasal spray: short-term efficacy and safety in seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Am J Rhinol Allergy 27:102-8. 2013
    ..This study was designed to assess the efficacy of the combination of MFNS and OXY for the relief of seasonal allergic rhinitis (SAR) symptoms...
  25. doi request reprint Preferences of adult patients with allergic rhinitis for the sensory attributes of fluticasone furoate versus fluticasone propionate nasal sprays: a randomized, multicenter, double-blind, single-dose, crossover study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Clin Ther 30:271-9. 2008
    ..Product attributes influence patient preference for intranasal corticosteroid therapy in allergic rhinitis (AR)...
  26. ncbi request reprint Treating acute rhinosinusitis: comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    J Allergy Clin Immunol 116:1289-95. 2005
    ..However, the efficacy of intranasal corticosteroid monotherapy for acute, uncomplicated rhinosinusitis is not established...
  27. doi request reprint MP29-02 (a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate) in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial of efficacy and safety
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 33:324-32. 2012
    ..In this study, MP29-02 provided more complete symptom relief than two widely used first-line AR treatments and was well tolerated...
  28. doi request reprint Pharmacotherapeutic strategies for allergic rhinitis: matching treatment to symptoms, disease progression, and associated conditions
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Allergy Asthma Proc 34:301-11. 2013
    ..A step-up/step-down approach to AR pharmacotherapy based on patient response may hold the potential for optimal control of AR symptoms while minimizing side effects and cost of treatment. ..
  29. doi request reprint Comprehensive report of olopatadine 0.6% nasal spray as treatment for children with seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 32:213-20. 2011
    ..Olopatadine is a safe and effective treatment for SAR patients as young as 6 years of age and it has been demonstrated to reduce disease impact on the lives of these children and their families...
  30. doi request reprint Efficacy of MP-AzeFlu in children with seasonal allergic rhinitis: Importance of paediatric symptom assessment
    William Berger
    Division of Basic Clinical Immunology, School of Medicine, University of California, Irvine, CA, USA
    Pediatr Allergy Immunol 27:126-33. 2016
    ....
  31. doi request reprint Overview of the treatment of allergic rhinitis and nonallergic rhinopathy
    Alexander N Greiner
    Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego 92123 Suite B, San Diego, CA 92123, USA
    Proc Am Thorac Soc 8:121-31. 2011
    ..Furthermore, treatment algorithms for AR and NAR are presented with a stepped-up, stepped-down scheme to aid the clinician in choosing appropriate therapy...
  32. doi request reprint Intranasal mometasone furoate therapy for allergic rhinitis symptoms and rhinitis-disturbed sleep
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 105:65-74. 2010
    ..Allergic rhinitis (AR) and related nasal congestion cause rhinitis-disturbed sleep (RDS). Intranasal corticosteroids reduce nasal congestion and improve sleep quality in AR but have not been extensively studied in RDS...
  33. ncbi request reprint Efficacy and safety of ciclesonide, 200 microg once daily, for the treatment of perennial allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123 2661, USA
    Ann Allergy Asthma Immunol 98:175-81. 2007
    ..Ciclesonide is an intranasal corticosteroid approved for the treatment of allergic rhinitis (AR)...
  34. ncbi request reprint Montelukast effectively treats the nighttime impact of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92109, USA
    Am J Rhinol 19:591-8. 2005
    ..Nighttime problems constitute a significant burden on the quality of life of patients with seasonal allergic rhinitis (SAR). The aim of this study was to evaluate the effectiveness of montelukast on nighttime AR symptoms...
  35. ncbi request reprint Efficacy and safety of clemastine-pseudoephedrine-acetaminophen versus pseudoephedrine-acetaminophen in the treatment of seasonal allergic rhinitis in a 1-day, placebo-controlled park study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Ann Allergy Asthma Immunol 90:79-86. 2003
    ..Patients with allergic rhinitis have a wide range of symptoms that are often treated with oral combination products that contain antihistamines, decongestants, and analgesics...
  36. ncbi request reprint Allergic rhinitis substantially impacts patient quality of life: findings from the Nasal Allergy Survey Assessing Limitations
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA, USA
    J Fam Pract 61:S5-10. 2012
    ....
  37. doi request reprint Beclomethasone dipropionate nasal aerosol with an integrated dose counter: functionality and performance
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 34:534-41. 2013
    ..4% reported two discrepancies. These results showed the functionality and reliability of the BDP nasal aerosol device with an integrated dose counter in a clinical setting. (ClinicalTrials.gov identifier: NCT01134705.). ..
  38. ncbi request reprint Intranasal corticosteroids in the treatment of acute rhinosinusitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Curr Allergy Asthma Rep 8:133-8. 2008
    ....
  39. ncbi request reprint Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA, USA
    Pediatr Allergy Immunol 15:253-60. 2004
    ..05). Fexofenadine, at doses of up to 60 mg b.i.d., is safe and non-sedating, and fexofenadine HCl 30 mg b.i.d. effectively reduces all seasonal allergic rhinitis symptoms in children aged 6-11 years...
  40. ncbi request reprint The role of the immune system in the pathogenesis of asthma and an overview of the diagnosis, classification, and current approach to treating the disease
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr B, San Diego, CA 92123, USA
    J Manag Care Pharm 9:8-13. 2003
    ....
  41. doi request reprint Efficacy and safety of once-daily fluticasone furoate nasal spray in children with seasonal allergic rhinitis treated for 2 wk
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    Pediatr Allergy Immunol 20:279-86. 2009
    ..Both doses of FF were well tolerated. These study results suggest that FF nasal spray administered once daily for 2 wk is well tolerated and effective for the treatment of SAR symptoms in children aged 2-11 yr...
  42. ncbi request reprint Formulation considerations of intranasal corticosteroids for the treatment of allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123 2661, USA
    Ann Allergy Asthma Immunol 98:12-21. 2007
    ..To examine how various aspects of an intranasal corticosteroid (INS) formulation may influence the efficacy, tolerability, and patient preference and adherence to INS therapy...
  43. ncbi request reprint Effect of desloratadine therapy on symptom scores and measures of nasal patency in seasonal allergic rhinitis: results of a single-center, placebo-controlled trial
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 96:363-8. 2006
    ..Desloratadine reduces symptoms and maintains nasal airflow in patients with seasonal allergic rhinitis (SAR) during experimental allergen exposure...
  44. ncbi request reprint Qualitative Development of the Rhinitis Control Assessment Test (RCAT), an Instrument for Evaluating Rhinitis Symptom Control
    Robert A Nathan
    1 Asthma and Allergy Associates, Colorado Springs, Colorado, USA 2 GlaxoSmithKline, Research Triangle Park, North Carolina, USA 3 Allergy and Asthma Medical Group and Research Center, San Diego, California, USA 4 Kaiser Permanente, San Diego, California, USA 5 House Ear Clinic, Los Angeles, California, USA 6 George Washington University School of Medicine, Washington, DC, USA 7 RTI Health Solutions, Research Triangle Park, North Carolina, USA
    Patient 3:91-9. 2010
    ....
  45. doi request reprint Asthma burden in the United States: results of the 2009 Asthma Insight and Management survey
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 33:36-46. 2012
    ..Asthma care in the United States remains suboptimal, indicating the need for continued improvements in patient management...
  46. ncbi request reprint The efficacy and safety of mometasone furoate delivered via a dry powder inhaler for the treatment of asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, University of California San Diego, 9610 Granite Ridge Drive, San Diego, CA 92123, USA
    J Asthma 43:765-72. 2006
    ..In conclusion, mometasone furoate provides primary care and specialty physicians with a safe, effective, and convenient option to meet the challenges of asthma management...
  47. ncbi request reprint Intranasal steroids: managing allergic rhinitis and tailoring treatment to patient preference
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    Allergy Asthma Proc 26:445-51. 2005
    ..The development of two new questionnaires, the Clinical Practice Patient Preference Questionnaire and the Clinical Trial Patient Preference Questionnaire, may prove useful in selecting the optimal treatment regimen for patients...
  48. ncbi request reprint Optimal management of community-acquired acute bacterial rhinosinusitis: the allergist's perspective
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Ann Allergy Asthma Immunol 96:390-7. 2006
    ....
  49. ncbi request reprint Addition of ibuprofen to pseudoephedrine and chlorpheniramine in the treatment of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Ann Allergy Asthma Immunol 93:452-9. 2004
    ..Standard over-the-counter therapy with antihistamines and nasal decongestants often does not completely relieve all symptoms associated with allergic rhinitis...
  50. ncbi request reprint Efficacy and patient satisfaction with cromolyn sodium nasal solution in the treatment of seasonal allergic rhinitis: a placebo-controlled study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Clin Ther 24:942-52. 2002
    ..The mast-cell stabilizer cromolyn sodium is available for over-the-counter (OTC) use in the prevention and treatment of allergic rhinitis...
  51. ncbi request reprint Allergic rhinitis: managing the pediatric spectrum
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 27:2-8. 2006
    ..Allergen immunotherapy can be a valuable adjunctive modality. Issues of compliance and convenience also are important considerations...
  52. ncbi request reprint Safety and efficacy of once-daily treatment with beclomethasone dipropionate nasal aerosol in subjects with perennial allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 33:249-57. 2012
    ..Additionally, treatment with BDP nasal aerosol was well tolerated with a safety profile comparable to that of placebo. This study was part of the clinical trial NCT01134705 registered in www.ClinicalTrials.gov...
  53. doi request reprint Mometasone furoate nasal spray for moderate-to-severe nasal congestion in subjects with seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 32:159-67. 2011
    ..Adverse events were infrequent and localized; the most common (epistaxis and pharyngolaryngeal pain) occurred in 1.0% of MFNS patients. MFNS q.d. provides sustained relief for nasal congestion and other SAR symptoms...
  54. ncbi request reprint Evaluation of the optimal oral antihistamine for patients with allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr, Suite B, San Diego, CA 92123, USA
    Mayo Clin Proc 80:1170-6. 2005
    ..Therefore, agents with broad therapeutic windows, based on both efficacy and safety, are expected to be more favorable; this therapeutic window should be understood by the primary care physician when prescribing a medication...
  55. pmc Relieving nasal congestion in children with seasonal and perennial allergic rhinitis: efficacy and safety studies of mometasone furoate nasal spray
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    World Allergy Organ J 6:5. 2013
    ..This analysis was conducted to investigate the effect of mometasone furoate nasal spray (MFNS) on congestion in children with AR...
  56. doi request reprint The role of nasal corticosteroids in the treatment of rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA
    Immunol Allergy Clin North Am 31:545-60. 2011
    ..Clinically, they have been shown to be the most effective class of nasal medications for treating allergic rhinitis and nonallergic rhinopathy, with no clear evidence that any specific INS is superior to others...
  57. ncbi request reprint Rhinosinusitis: Establishing definitions for clinical research and patient care
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, Department of Pediatrics, University of California, San Diego 92123, USA
    Otolaryngol Head Neck Surg 131:S1-62. 2004
  58. doi request reprint Phenylephrine hydrochloride modified-release tablets for nasal congestion: a randomized, placebo-controlled trial in allergic rhinitis patients
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California
    Ann Allergy Asthma Immunol 116:66-71. 2016
    ..The US Food and Drug Administration recommended clinical trials to evaluate the efficacy and safety of PEH in patients with this condition...
  59. ncbi request reprint An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123 2661, USA
    J Allergy Clin Immunol 115:791-6. 2005
    ..R112 inhibits Syk kinase, a transducer of signaling through the Fcepsilon receptor of mast cells, blocking mast cell responses to allergic stimuli...
  60. doi request reprint Burden of allergic rhinitis: results from the Pediatric Allergies in America survey
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    J Allergy Clin Immunol 124:S43-70. 2009
    ..Findings from this national survey have identified important challenges to the management of AR, suggesting that its burden on children in the United States has been significantly underestimated...
  61. doi request reprint Sleep, quality of life, and productivity impact of nasal symptoms in the United States: findings from the Burden of Rhinitis in America survey
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 30:244-54. 2009
    ..05). Individuals who suffer from AR symptoms experience a substantial burden on their ability to sleep, quality of life, cognitive function, and school/workplace productivity...
  62. ncbi request reprint Efficacy and safety of low-dose fluticasone propionate compared with montelukast for maintenance treatment of persistent asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Mayo Clin Proc 77:437-45. 2002
    ..To compare the long-term effects of an inhaled corticosteroid with those of a leukotriene modifier on measures of clinical efficacy, subject preference, and safety in patients with persistent asthma...
  63. doi request reprint Use of the Asthma Control Questionnaire to predict future risk of asthma exacerbation
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, Calif 92123, USA
    J Allergy Clin Immunol 127:167-72. 2011
    ..Direct correlation of assessments of a validated composite measure such as the Asthma Control Questionnaire (ACQ) and risk of exacerbation has not been previously demonstrated in a randomized controlled trial...