Affiliation: University of Luxembourg
- Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-overZiad Al Tanoury
Laboratory of Cytoskeleton and Cell Plasticity, Life Sciences Research Unit, University of Luxembourg, Luxembourg City, Luxembourg
PLoS ONE 5:e9210. 2010..Phosphorylation of L-plastin on residue Ser5 increases its F-actin binding activity and is required for L-plastin-mediated cell invasion...
- A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transitionMichèle Moes
Cytoskeleton and Cell Plasticity Lab, Life Sciences Research Unit FSCT, University of Luxembourg, Luxembourg, Luxembourg
PLoS ONE 7:e35440. 2012..g. SNAI1/2, ZEB1/2 and TWIST1) and microRNAs. Here we investigated microRNAs regulated by SNAI1 and their potential role in the regulatory networks underlying epithelial plasticity...
- Advanced spot quality analysis in two-colour microarray experimentsMikalai Yatskou
Microarray Center LBMAGM, CRP Sante, 84 rue Val Fleuri, L 1526, Luxembourg
BMC Res Notes 1:80. 2008..Therefore, improving and standardizing the statistical approaches of spot quality control are essential to facilitate the overall analysis of microarray data and subsequent extraction of biological information...
- Design and evaluation of Actichip, a thematic microarray for the study of the actin cytoskeletonJean Muller
Laboratoire de Biologie Moleculaire, d Analyse Génique et de Modélisation, Centre de Recherche Public Santé, 84 rue Val Fleuri, L 1526 Luxembourg, Luxembourg
BMC Genomics 8:294. 2007..Here we report the development of a dedicated microarray, the Actichip, containing 60-mer oligonucleotide probes for 327 genes selected for transcriptome analysis of the human actin cytoskeleton...
- MIR@NT@N: a framework integrating transcription factors, microRNAs and their targets to identify sub-network motifs in a meta-regulation network modelAntony Le Béchec
Cytoskeleton and Cell Plasticity Lab, Life Sciences Research Unit FSCT, University of Luxembourg, L 1511 Luxembourg, Luxembourg
BMC Bioinformatics 12:67. 2011..An integrative computational resource generating a comprehensive view of these regulatory molecular interactions at a genome-wide scale would be of great interest to biologists, but is not available to date...
- A mathematical model of actin filament turnover for fitting FRAP dataAliaksandr A Halavatyi
Cytoskeleton and Cell Plasticity Laboratory, Life Sciences Research Unit, Faculty of Science, Technology and Communication, University of Luxembourg, Campus Limpertsberg, Luxembourg 1511, Luxembourg
Eur Biophys J 39:669-77. 2010..Additionally, we provide a computational tool that integrates the model and that can be used for interpretation of FRAP data on actin cytoskeleton...