Nick J Lowe

Summary

Publications

  1. ncbi request reprint Dispelling the myth: appropriate use of poly-L-lactic acid and clinical considerations
    N J Lowe
    Cranley Clinic, London, UK, and UCLA School of Medicine, Los Angeles, CA, USA
    J Eur Acad Dermatol Venereol 20:2-6. 2006
  2. ncbi request reprint A multicenter, double-blind, randomized, placebo-controlled study of the efficacy and safety of botulinum toxin type A in the treatment of glabellar lines
    J Alastair Carruthers
    Vancouver Hospital, Vancouver, British Columbia, Canada
    J Am Acad Dermatol 46:840-9. 2002
  3. ncbi request reprint Double-blind, randomized, placebo-controlled, dose-response study of the safety and efficacy of botulinum toxin type A in subjects with crow's feet
    Nicholas J Lowe
    Cranley Clinic, London, United Kingdom
    Dermatol Surg 31:257-62. 2005
  4. ncbi request reprint The place of botulinum toxin type A in the treatment of focal hyperhidrosis
    N Lowe
    Cranley Clinic, 3 Harcourt House, 19a Cavendish Square, London W1G 0PN, UK
    Br J Dermatol 151:1115-22. 2004
  5. ncbi request reprint Pilot study to determine the efficacy of ALA-PDT photo-rejuvenation for the treatment of facial ageing
    Nicholas J Lowe
    Cranley Clinic, London, UK
    J Cosmet Laser Ther 7:159-62. 2005
  6. ncbi request reprint Tazarotene 0.1% cream versus tretinoin 0.05% emollient cream in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized, parallel-group study
    Nicholas Lowe
    Department of Dermatology, University of Michigan Medical Center, Ann Arbor, MI, USA
    J Cosmet Laser Ther 6:79-85. 2004
  7. ncbi request reprint Cosmetic uses of botulinum toxins for lower aspects of the face and neck
    Nicholas J Lowe
    Division of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Clin Dermatol 22:18-22. 2004
  8. ncbi request reprint Injectable hyaluronic acid implant for malar and mental enhancement
    Nicholas J Lowe
    The Cranley Clinic for Dermatology, London, United Kingdom
    Dermatol Surg 32:881-5; discussion 885. 2006
  9. ncbi request reprint Tazarotene versus tazarotene plus hydroquinone in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized study
    Nicholas Lowe
    UCLA School of Medicine, Santa Monica, CA, USA
    J Cosmet Laser Ther 8:121-7. 2006
  10. ncbi request reprint Botulinum toxin type A in the treatment of primary axillary hyperhidrosis: a 52-week multicenter double-blind, randomized, placebo-controlled study of efficacy and safety
    Nicholas J Lowe
    University of California Los Angeles School of Medicine, USA
    J Am Acad Dermatol 56:604-11. 2007

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Dispelling the myth: appropriate use of poly-L-lactic acid and clinical considerations
    N J Lowe
    Cranley Clinic, London, UK, and UCLA School of Medicine, Los Angeles, CA, USA
    J Eur Acad Dermatol Venereol 20:2-6. 2006
    ..Sculptra, both in formulation and use, is vastly superior to New-Fill and clinical experience with this product dispels the myths associated with the earlier types of injectable PLLA...
  2. ncbi request reprint A multicenter, double-blind, randomized, placebo-controlled study of the efficacy and safety of botulinum toxin type A in the treatment of glabellar lines
    J Alastair Carruthers
    Vancouver Hospital, Vancouver, British Columbia, Canada
    J Am Acad Dermatol 46:840-9. 2002
    ..Botulinum toxin type A (BTX-A) is widely used for facial esthetics but is incompletely studied...
  3. ncbi request reprint Double-blind, randomized, placebo-controlled, dose-response study of the safety and efficacy of botulinum toxin type A in subjects with crow's feet
    Nicholas J Lowe
    Cranley Clinic, London, United Kingdom
    Dermatol Surg 31:257-62. 2005
    ..Published evidence suggests that botulinum toxin type A (BTX-A) is an effective treatment for crow's feet. However, few dose-ranging studies have been performed...
  4. ncbi request reprint The place of botulinum toxin type A in the treatment of focal hyperhidrosis
    N Lowe
    Cranley Clinic, 3 Harcourt House, 19a Cavendish Square, London W1G 0PN, UK
    Br J Dermatol 151:1115-22. 2004
    ..It can be localized or generalized, commonly affecting the axillae, palms, soles or face, and can have a substantial negative effect on a patient's quality of life...
  5. ncbi request reprint Pilot study to determine the efficacy of ALA-PDT photo-rejuvenation for the treatment of facial ageing
    Nicholas J Lowe
    Cranley Clinic, London, UK
    J Cosmet Laser Ther 7:159-62. 2005
    ..The second study was to establish if ALA-PDT treatments improve the signs of ageing...
  6. ncbi request reprint Tazarotene 0.1% cream versus tretinoin 0.05% emollient cream in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized, parallel-group study
    Nicholas Lowe
    Department of Dermatology, University of Michigan Medical Center, Ann Arbor, MI, USA
    J Cosmet Laser Ther 6:79-85. 2004
    ..To compare the efficacy and tolerability of tazarotene 0.1% cream and tretinoin 0.05% emollient cream in the treatment of photodamaged facial skin...
  7. ncbi request reprint Cosmetic uses of botulinum toxins for lower aspects of the face and neck
    Nicholas J Lowe
    Division of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Clin Dermatol 22:18-22. 2004
    ..Examples of combinations that may be used with BTX-A resurfacing, nonablative skin rejuvenation and skin fillers. Although little used at present, Botulinum Toxin B will be briefly discussed...
  8. ncbi request reprint Injectable hyaluronic acid implant for malar and mental enhancement
    Nicholas J Lowe
    The Cranley Clinic for Dermatology, London, United Kingdom
    Dermatol Surg 32:881-5; discussion 885. 2006
    ..The use of a thicker injectable implant version of one of the hyaluronic acid dermal fillers (Restylane SubQ, Q-Med, Uppsala, Sweden) is described...
  9. ncbi request reprint Tazarotene versus tazarotene plus hydroquinone in the treatment of photodamaged facial skin: a multicenter, double-blind, randomized study
    Nicholas Lowe
    UCLA School of Medicine, Santa Monica, CA, USA
    J Cosmet Laser Ther 8:121-7. 2006
    ..To compare the efficacy and tolerability of tazarotene plus hydroquinone versus tazarotene alone in the treatment of facial photodamage...
  10. ncbi request reprint Botulinum toxin type A in the treatment of primary axillary hyperhidrosis: a 52-week multicenter double-blind, randomized, placebo-controlled study of efficacy and safety
    Nicholas J Lowe
    University of California Los Angeles School of Medicine, USA
    J Am Acad Dermatol 56:604-11. 2007
    ..The long-term effects of botulinum toxin type A (BoNTA) on the global impairment associated with severe primary axillary hyperhidrosis have not been comprehensively assessed relative to placebo...
  11. ncbi request reprint Bilateral, double-blind, randomized comparison of 3 doses of botulinum toxin type A and placebo in patients with crow's feet
    Nicholas J Lowe
    Clinical Research Specialists, Santa Monica, CA 90404, USA
    J Am Acad Dermatol 47:834-40. 2002
    ..Optimum dosing for botulinum toxin type A (BTX-A) in crow's feet remains to be defined...
  12. ncbi request reprint Overview of botulinum neurotoxins
    Nicholas J Lowe
    Cranley Clinic, London, UK
    J Cosmet Laser Ther 9:11-6. 2007
    ....
  13. doi request reprint Optimizing poly-L-lactic acid use
    Nick J Lowe
    Cranley Clinic, London, United Kingdom
    J Cosmet Laser Ther 10:43-6. 2008
    ..This article provides an overview of injectable devices, specifically focusing on PLLA in cosmetic application and optimal administration techniques to maximize efficacy and duration of effect...
  14. ncbi request reprint Repeat courses of intravenous alefacept in patients with chronic plaque psoriasis provide consistent safety and efficacy
    Nick J Lowe
    Clinical Research Specialists, Santa Monica, California, USA
    Int J Dermatol 42:224-30. 2003
    ..This open-label study evaluated the safety and tolerability, efficacy, and pharmacodynamics of repeat courses of alefacept in men and women with chronic plaque psoriasis. This article reports the interim results of this ongoing study...
  15. ncbi request reprint Microwave delivery system for lower leg telangiectasia
    N J Lowe
    J Cutan Laser Ther 2:3-7. 2000
    ..Some patients do not respond well and others have a variety of local side-effects. Alternative treatments would be helpful in managing many patients...
  16. ncbi request reprint An overview of ultraviolet radiation, sunscreens, and photo-induced dermatoses
    N J Lowe
    Department of Dermatology, University of California School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
    Dermatol Clin 24:9-17. 2006
    ..This article reviews the protectiveness of sunscreens and assays that predict their levels of protection...
  17. ncbi request reprint Topical photodynamic therapy in clinical dermatology
    T Kormeili
    UCLA School of Medicine, Santa Monica, CA 90404, U S A
    Br J Dermatol 150:1061-9. 2004
    ..This paper will discuss the various applications and data on the use of topical PDT in dermatology...
  18. ncbi request reprint A randomized trial of the efficacy of a new micronized formulation versus a standard formulation of isotretinoin in patients with severe recalcitrant nodular acne
    J S Strauss
    Department of Dermatology, University of Iowa Health Care, Iowa City, IA 52242-1090, USA
    J Am Acad Dermatol 45:187-95. 2001
    ....
  19. ncbi request reprint Safety of a new micronized formulation of isotretinoin in patients with severe recalcitrant nodular acne: A randomized trial comparing micronized isotretinoin with standard isotretinoin
    J S Strauss
    Department of Dermatology, University of Iowa Health Care, Iowa City, IA 52242-2090, USA
    J Am Acad Dermatol 45:196-207. 2001
    ..CONCLUSION: Micronized isotretinoin appears to have a safety profile similar to that of standard isotretinoin and to carry a lower risk of mucocutaneous events and hypertriglyceridemia...
  20. ncbi request reprint Tazarotene cream for the treatment of facial photodamage: a multicenter, investigator-masked, randomized, vehicle-controlled, parallel comparison of 0.01%, 0.025%, 0.05%, and 0.1% tazarotene creams with 0.05% tretinoin emollient cream applied once daily f
    S Kang
    Department of Dermatology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
    Arch Dermatol 137:1597-604. 2001
    ..To assess the safety and efficacy of 4 concentrations of tazarotene cream in the treatment of facial photodamage...
  21. ncbi request reprint Light-emitting diode 415 nm in the treatment of inflammatory acne: an open-label, multicentric, pilot investigation
    J F Tremblay
    UCLA School of Medicine, Los Angeles, CA, USA
    J Cosmet Laser Ther 8:31-3. 2006
    ..Phototherapy using blue light has been proven in the treatment of acne vulgaris and offers the clinician an effective alternative...
  22. ncbi request reprint The use of photodynamic therapy in dermatology: results of a consensus conference
    Mark S Nestor
    Center for Cosmetic Advancement, Aventura, FL, USA
    J Drugs Dermatol 5:140-54. 2006
    ..Appropriate light sources are available in many dermatology offices. The expanding clinical and financial benefits of PDT justify the purchase of an appropriate light source...
  23. ncbi request reprint Adverse reactions to dermal fillers: review
    Nicholas J Lowe
    Division of Dermatology, Department of Medicine UCLA, David Geffen School of Medicine, Los Angeles, California, USA
    Dermatol Surg 31:1616-25. 2005
    ..With the increase in products available and the rise in the number of patients seeking this type of intervention, it is crucial that both the physician and the patient are fully cognizant of the risks involved with each product...
  24. ncbi request reprint A comparison of two botulinum type a toxin preparations for the treatment of glabellar lines: double-blind, randomized, pilot study
    Philippa L Lowe
    Cranley Clinic, London, UK
    Dermatol Surg 31:1651-4. 2005
    ..Botulinum toxins have been proven effective for reducing facial lines. There are two commercial types of botulinum toxin type A available in many countries but no published comparison studies...
  25. doi request reprint Comparisons among botulinum toxins: an evidence-based review
    Arnold W Klein
    David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, Calif, USA
    Plast Reconstr Surg 121:413e-422e. 2008
    ..A number of serotypes and formulations are available worldwide. Similarities and differences among these toxins were evaluated by reviewing the existing literature...
  26. ncbi request reprint 3D photography and lip filler: a novel assay
    Philippa Lowe
    Cranley Clinic London and Clinical Research Specialists, Santa Monica, CA, USA
    J Cosmet Laser Ther 9:237-40. 2007
    ..Injectable fillers have been used for a considerable number of years in aesthetic dermatology, including the use of lip augmentation. There has been little attempt to scientifically measure the degree of filler augmentation...
  27. ncbi request reprint Facial aesthetics: achieving the natural, relaxed look
    Alastair Carruthers
    Department of Dermatology and Skin Science, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    J Cosmet Laser Ther 9:6-10. 2007
    ..The article also offers suggestions intended to help clinicians provide each patient with appropriate outcomes and satisfaction...
  28. ncbi request reprint Botulinum toxin type A gives adjunctive benefit to periorbital laser resurfacing
    Paul S Yamauchi
    UCLA School of Medicine, Los Angeles, CA, USA
    J Cosmet Laser Ther 6:145-8. 2004
    ..Rejuvenation of this area should therefore be optimized by combining treatments that approach the different causative factors...
  29. ncbi request reprint Efficacy and safety of botulinum toxin type a in the treatment of palmar hyperhidrosis: a double-blind, randomized, placebo-controlled study
    Nicholas J Lowe
    Clinical Research Specialists, Santa Monica, CA 90404, USA
    Dermatol Surg 28:822-7. 2002
    ..Recent studies demonstrate that botulinum toxin type A (BTX-A) decreases palmar hyperhidrosis...
  30. ncbi request reprint Efficacy of 0.1% tazarotene cream for the treatment of photodamage: a 12-month multicenter, randomized trial
    Tania J Phillips
    Boston University School of Medicine, Boston, MA 02118, USA
    Arch Dermatol 138:1486-93. 2002
    ..To determine the efficacy and safety of 0.1% tazarotene cream for the treatment of photodamage...
  31. ncbi request reprint Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial
    David M Pariser
    Division of Dermatology, Eastern Virginia Medical School, and Virginia Clinical Research Inc, Norfolk, VA, USA
    J Am Acad Dermatol 48:227-32. 2003
    ..Methyl aminolevulinate (MAL) (Metvix, PhotoCure, Oslo, Norway) leads to selective accumulation of photoactive porphyrins in premalignant skin lesions and makes the lesions susceptible to phototoxic effects on illumination with red light...
  32. ncbi request reprint Botulinum toxins types A and B for brow furrows: preliminary experiences with type B toxin dosing
    Nicholas J Lowe
    UCLA School of Medicine, Los Angeles, CA, USA
    J Cosmet Laser Ther 4:15-8. 2002
    ..There has been little comparison on the efficacy of the two different types of botulinum toxins, nor is there information on appropriate dosing of BTX-B for facial muscles...
  33. ncbi request reprint Tazarotene cream in the treatment of psoriasis: Two multicenter, double-blind, randomized, vehicle-controlled studies of the safety and efficacy of tazarotene creams 0.05% and 0.1% applied once daily for 12 weeks
    Gerald D Weinstein
    University of California, Irvine, USA
    J Am Acad Dermatol 48:760-7. 2003
    ..Tazarotene in a gel formulation is widely used in the treatment of psoriasis...
  34. ncbi request reprint Botulinum toxin type A in the treatment of bilateral primary axillary hyperhidrosis: efficacy and duration with repeated treatments
    Phillipa L Lowe
    Cranley Clinic, London, United Kingdom
    Dermatol Surg 29:545-8. 2003
    ..Botulinum toxin type A (BTX-A) has been shown to be effective for the temporary reduction of local hyperhidrosis...
  35. ncbi request reprint Effect of a single course of isotretinoin therapy on bone mineral density in adolescent patients with severe, recalcitrant, nodular acne
    John J DiGiovanna
    Division of Dermatopharmacology, Department of Dermatology, Brown Medical School Rhode Island Hospital, Providence, RI 02903, USA
    J Am Acad Dermatol 51:709-17. 2004
    ..The effect of short-term (4-5 months) therapy at the lower dose recommended for acne on bone development in younger, growing adolescent (12-17 years) patients has not been well studied...
  36. ncbi request reprint Botulinum toxin types A and B: comparison of efficacy, duration, and dose-ranging studies for the treatment of facial rhytides and hyperhidrosis
    Paul S Yamauchi
    Clinical Research Specialists, Santa Monica, California 90404, USA
    Clin Dermatol 22:34-9. 2004
    ..In addition, the treatment of hyperhidrosis with type-A and type-B botulinum toxin will also be discussed...
  37. ncbi request reprint Retinoid therapy for psoriasis
    Paul S Yamauchi
    Clinical Research Specialists, 2001 Santa Monica Boulevard, Suite 490W, Santa Monica, CA 90404, USA
    Dermatol Clin 22:467-76, x. 2004
    ..In addition, new retinoid analogues that are undergoing clinical investigation are mentioned. Finally, potential toxicities and adverse effects associated with retinoids are discussed...
  38. doi request reprint Etanercept therapy allows the tapering of methotrexate and sustained clinical responses in patients with moderate to severe psoriasis
    Paul S Yamauchi
    Dermatology Institute and Skin Care Center, Santa Monica, and Division of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Int J Dermatol 47:202-4. 2008
    ..Here we describe sustained clinical responses in 6 patients with psoriasis following gradual cessation of methotrexate through the addition of etanercept therapy...
  39. ncbi request reprint The treatment of psoriasis and psoriatic arthritis with etanercept: practical considerations on monotherapy, combination therapy, and safety
    Paul S Yamauchi
    Clinical Research Specialists, 2001 Santa Monica Boulevard, Suite 490W, Santa Monica, CA 90404, USA
    Dermatol Clin 22:449-59, ix. 2004
    ..With specific antagonism directed against tumor necrosis factor-alpha, etanercept has demonstrated remarkable efficacy in the treatment of psoriasis and psoriatic arthritis...
  40. ncbi request reprint Recognition, diagnosis, and treatment of primary focal hyperhidrosis
    John Hornberger
    Stanford University School of Medicine, USA
    J Am Acad Dermatol 51:274-86. 2004
  41. ncbi request reprint Current and emerging therapeutic modalities for hyperhidrosis, part 1: conservative and noninvasive treatments
    Ramin Ram
    Cedars Sinai Medical Center, Los Angeles, California, USA
    Cutis 79:211-7. 2007
    ..This article reviews HH and the conservative treatments for the condition...
  42. ncbi request reprint Current and emerging therapeutic modalities for hyperhidrosis, part 2: moderately invasive and invasive procedures
    Ramin Ram
    Cedars Sinai Medical Center, University of Southern California, Keck School of Medicine, Department of Dermatology, Los Angeles, USA
    Cutis 79:281-8. 2007
    ..This article reviews moderately invasive and invasive procedures, such as botulinum toxin, curettage, and endoscopic thoracic sympathectomy (ETS), and compares their advantages and disadvantages in safety and efficacy...
  43. ncbi request reprint Use of topical metronidazole in moderate to severe rosacea
    Nicholas J Lowe
    Department of Dermatology, UCLA School of Medicine, Santa Monica, California 90404, USA
    Adv Ther 20:177-90. 2003
    ..Although original studies involving topical metronidazole 0.75% used a twice-daily regimen, subsequent work has shown that this formulation used once daily is as effective as 1% metronidazole...
  44. ncbi request reprint Current systemic therapies for psoriasis: where are we now?
    Paul S Yamauchi
    Clinical Research Specialists, UCLA School of Medicine, 2001 Santa Monica Boulevard, Santa Monica, CA 90404, USA
    J Am Acad Dermatol 49:S66-77. 2003
    ..However, such potential toxicities arising from these medications can largely be avoided if proper patient selection and close monitoring are performed...