Lawrence Long

Summary

Publications

  1. doi request reprint The high cost of second-line antiretroviral therapy for HIV/AIDS in South Africa
    Lawrence Long
    Health Economics and Epidemiology Research Office, Wits Health Consortium, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 24:915-9. 2010
  2. pmc Retention in care, resource utilization, and costs for adults receiving antiretroviral therapy in Zambia: a retrospective cohort study
    Callie A Scott
    Center for Global Health and Development, Boston University, Crosstown Center, 3rd Floor, 801 Massachusetts Avenue, Boston, MA 02118, USA
    BMC Public Health 14:296. 2014
  3. pmc Treatment outcomes and cost-effectiveness of shifting management of stable ART patients to nurses in South Africa: an observational cohort
    Lawrence Long
    Health Economics and Epidemiology Research Office, Wits Health Consortium, Johannesburg, South Africa
    PLoS Med 8:e1001055. 2011
  4. doi request reprint Impact of choice of NRTI in first-line antiretroviral therapy: a cohort analysis of stavudine vs. tenofovir
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 19:490-8. 2014
  5. pmc Increases in regimen durability associated with the introduction of tenofovir at a large public-sector clinic in Johannesburg, South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Faculty of Health Sciences, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 16:18794. 2013
  6. pmc Citizenship status and engagement in HIV care: an observational cohort study to assess the association between reporting a national ID number and retention in public-sector HIV care in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    BMJ Open 7:e013908. 2017
  7. pmc The relation between efavirenz versus nevirapine and virologic failure in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 17:19065. 2014
  8. pmc The impact of choice of NNRTI on short-term treatment outcomes among HIV-infected patients prescribed tenofovir and lamivudine in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 8:e71719. 2013
  9. pmc Scaling up Xpert MTB/RIF technology: the costs of laboratory- vs. clinic-based roll-out in South Africa
    Kathryn Schnippel
    Health Economics and Epidemiology Research Office, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 17:1142-51. 2012
  10. pmc Rapid point-of-care CD4 testing at mobile HIV testing sites to increase linkage to care: an evaluation of a pilot program in South Africa
    Bruce A Larson
    Department of International Health, Center for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown 3rd Floor, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 61:e13-7. 2012

Collaborators

Detail Information

Publications21

  1. doi request reprint The high cost of second-line antiretroviral therapy for HIV/AIDS in South Africa
    Lawrence Long
    Health Economics and Epidemiology Research Office, Wits Health Consortium, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 24:915-9. 2010
    ..This information is crucial for planning and budgeting...
  2. pmc Retention in care, resource utilization, and costs for adults receiving antiretroviral therapy in Zambia: a retrospective cohort study
    Callie A Scott
    Center for Global Health and Development, Boston University, Crosstown Center, 3rd Floor, 801 Massachusetts Avenue, Boston, MA 02118, USA
    BMC Public Health 14:296. 2014
    ..We estimated retention in care, the quantity of resources utilized, and costs for a retrospective cohort of adults initiating ART under routine clinical conditions in Zambia...
  3. pmc Treatment outcomes and cost-effectiveness of shifting management of stable ART patients to nurses in South Africa: an observational cohort
    Lawrence Long
    Health Economics and Epidemiology Research Office, Wits Health Consortium, Johannesburg, South Africa
    PLoS Med 8:e1001055. 2011
    ..This study evaluated the cost-effectiveness of down-referring stable antiretroviral therapy (ART) patients from a doctor-managed, hospital-based ART clinic to a nurse-managed primary health care facility in Johannesburg, South Africa...
  4. doi request reprint Impact of choice of NRTI in first-line antiretroviral therapy: a cohort analysis of stavudine vs. tenofovir
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 19:490-8. 2014
    ..We examined treatment outcomes over 24 months amongst patients initiated on tenofovir-based vs. stavudine-based first-line regimens...
  5. pmc Increases in regimen durability associated with the introduction of tenofovir at a large public-sector clinic in Johannesburg, South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Faculty of Health Sciences, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 16:18794. 2013
    ..We evaluated changes over time in regimen durability at the Themba Lethu Clinic, Johannesburg, South Africa...
  6. pmc Citizenship status and engagement in HIV care: an observational cohort study to assess the association between reporting a national ID number and retention in public-sector HIV care in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    BMJ Open 7:e013908. 2017
    ..The objective of this analysis was to compare programmatic treatment outcomes by citizenship status in an urban clinic in SA...
  7. pmc The relation between efavirenz versus nevirapine and virologic failure in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 17:19065. 2014
    ..We investigated this hypothesis in a cohort of HIV-positive patients at a large HIV treatment clinic in South Africa...
  8. pmc The impact of choice of NNRTI on short-term treatment outcomes among HIV-infected patients prescribed tenofovir and lamivudine in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 8:e71719. 2013
    ..We sought to compare outcomes among those taking nevirapine vs. efavirenz with tenofovir and lamivudine...
  9. pmc Scaling up Xpert MTB/RIF technology: the costs of laboratory- vs. clinic-based roll-out in South Africa
    Kathryn Schnippel
    Health Economics and Epidemiology Research Office, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 17:1142-51. 2012
    ..We used recent South African data to compare the cost of placing Xpert at points of TB treatment (all primary clinics and hospitals) with the cost of placement at sub-district laboratories...
  10. pmc Rapid point-of-care CD4 testing at mobile HIV testing sites to increase linkage to care: an evaluation of a pilot program in South Africa
    Bruce A Larson
    Department of International Health, Center for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown 3rd Floor, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 61:e13-7. 2012
    ..We report results from this pilot program for patients testing positive (n = 508) from May to October 2010...
  11. pmc Outcomes of stable HIV-positive patients down-referred from a doctor-managed antiretroviral therapy clinic to a nurse-managed primary health clinic for monitoring and treatment
    Alana T Brennan
    Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 25:2027-36. 2011
    ....
  12. pmc Treatment outcomes of over 1000 patients on second-line, protease inhibitor-based antiretroviral therapy from four public-sector HIV treatment facilities across Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health . 2016
    ..To report predictors of outcomes of second-line ART for HIV treatment in a resource-limited setting...
  13. pmc Can Short-Term Use of Electronic Patient Adherence Monitoring Devices Improve Adherence in Patients Failing Second-Line Antiretroviral Therapy? Evidence from a Pilot Study in Johannesburg, South Africa
    Denise Evans
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    AIDS Behav 20:2717-2728. 2016
    ..9 vs. 40.9 %; RR 1.12; 95 % CI 0.81-1.56). In patients with an elevated viral load on second-line ART electronic adherence monitoring was associated with a modest, but not significant, improvement in viral suppression...
  14. pmc Poor CD4 recovery and risk of subsequent progression to AIDS or death despite viral suppression in a South African cohort
    Simbarashe Takuva
    Clinical HIV Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 17:18651. 2014
    ..The prognostic role of CD4 response in the first six months of treatment in patients achieving early viral suppression during HIV treatment is unclear...
  15. doi request reprint Costs of inpatient treatment for multi-drug-resistant tuberculosis in South Africa
    Kathryn Schnippel
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 18:109-16. 2013
    ..To inform new strategies for MDR-TB management, we estimated the per-patient cost (USD 2011) of inpatient MDR-TB treatment...
  16. pmc Treatment outcomes of HIV-positive patients on first-line antiretroviral therapy in private versus public HIV clinics in Johannesburg, South Africa
    Faith Moyo
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Clin Epidemiol 8:37-47. 2016
    ..While many studies have investigated patient-level causes of poor treatment outcomes, data on the effect of health systems on ART outcomes are scarce...
  17. doi request reprint A meta-analysis assessing all-cause mortality in HIV-exposed uninfected compared with HIV-unexposed uninfected infants and children
    Alana T Brennan
    aDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA bHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa cDepartment of Epidemiology, Boston University School of Public Health dDepartment of Pediatrics, Boston University School of Medicine, Boston, Massachusetts, USA
    AIDS 30:2351-60. 2016
    ..Conduct a meta-analysis examining differential all-cause mortality rates between HIV-exposed uninfected (HEU) infants and children as compared with their HIV-unexposed uninfected (HUU) counterparts...
  18. pmc Brief Report: Does Most Mortality in Patients on ART Occur in Care or After Lost to Follow-Up? Evidence From the Themba Lethu Clinic, South Africa
    Eric P Budgell
    Health Economics and Epidemiology Research Office HE2RO, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Right to Care, Johannesburg, South Africa Center for Global Health and Development, Boston University, Boston, MA and Department of Epidemiology, Boston University School of Public Health, Boston University, Boston, MA
    J Acquir Immune Defic Syndr 70:323-8. 2015
    ..4% to 42.5%). Although mortality rates in patients lost were much higher than in care, most ART-related mortality occurred on treatment. ..
  19. pmc The impact and cost of scaling up GeneXpert MTB/RIF in South Africa
    Gesine Meyer-Rath
    Health Economics and Epidemiology Research Office HE2RO, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 7:e36966. 2012
    ....
  20. doi request reprint Intensive adherence counselling for HIV-infected individuals failing second-line antiretroviral therapy in Johannesburg, South Africa
    Matthew P Fox
    Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 21:1131-7. 2016
    ..This study was performed to describe one such approach to adherence optimisation...
  21. doi request reprint Mortality in the First 3 Months on Antiretroviral Therapy Among HIV-Positive Adults in Low- and Middle-income Countries: A Meta-analysis
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa andDepartments of Epidemiology Global Health, Boston University School of Public Health, Boston, MA
    J Acquir Immune Defic Syndr 73:1-10. 2016
    ..Continued financial investments by multinational partners and the implementation of creative interventions to mitigate multidimensional complex barriers of accessing care and treatment for HIV are needed. ..