Zhan Ju Liu

Summary

Publications

  1. ncbi Current strategies for the treatment of ulcerative colitis
    Praveen K Yadav
    Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Recent Pat Inflamm Allergy Drug Discov 3:65-72. 2009
  2. doi Il-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease
    Zhanju Liu
    Department of Gastroenterology, Shanghai Tenth People s Hospital, Tongji University School of Medicine, Shanghai, China
    Inflamm Bowel Dis 15:1133-44. 2009
  3. pmc Herbal medicine in the treatment of ulcerative colitis
    Fei Ke
    Department of Gastroenterology, The Shanghai Tenth People s Hospital, Tongji University, No 301 Yanchang Road, Shanghai, China
    Saudi J Gastroenterol 18:3-10. 2012
  4. pmc Potential role of NK cells in the pathogenesis of inflammatory bowel disease
    Praveen K Yadav
    Department of Gastroenterology, The Shanghai Tenth People s Hospital, Tongji University School of Medicine, Shanghai, China
    J Biomed Biotechnol 2011:348530. 2011
  5. pmc Microbiota regulation of inflammatory bowel disease and colorectal cancer
    Zhanju Liu
    Department of Gastroenterology, The Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China Electronic address
    Semin Cancer Biol 23:543-52. 2013
  6. ncbi [Association between HLA-Cw polymorphism and inflammatory bowel disease]
    Hui Xia Zhang
    Department of Gastroenterology, Tongji University, Shanghai, China
    Zhonghua Nei Ke Za Zhi 50:856-8. 2011
  7. pmc Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease
    Zhan Ju Liu
    Department of Gastroenterology, Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China
    World J Gastroenterol 15:5784-8. 2009
  8. doi The increased expression of IL-23 in inflammatory bowel disease promotes intraepithelial and lamina propria lymphocyte inflammatory responses and cytotoxicity
    Zhanju Liu
    Department of Gastroenterology, The Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China
    J Leukoc Biol 89:597-606. 2011
  9. ncbi Blockage of tumor necrosis factor prevents intestinal mucosal inflammation through down-regulation of interleukin-23 secretion
    Zhanju Liu
    Laboratory of Immunopathology, Department of Gastroenterology, The Second Affiliated Hospital, Zhengzhou University, 2 Jingba Road, Zhengzhou 450014, China
    J Autoimmun 29:187-94. 2007
  10. ncbi Hyperamylasemia, reactive plasmacytosis, and immune abnormalities in a patient with celiac disease
    Zhanju Liu
    Laboratory of Immunopathology, The Institute of Digestive Diseases, Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Dig Dis Sci 52:1444-7. 2007

Collaborators

  • P W Hellings
  • Ping Chang Yang
  • Xingpeng Wang
  • Min Zhang
  • Yingzi Cong
  • Weiping Zou
  • Liang Zhong
  • Dian Chun Fang
  • Li Yang
  • Ying Du
  • Yulan Liu
  • Ai Ping Bai
  • Zhikang Peng
  • P Rutgeerts
  • K Geboes
  • Gang Xu
  • Praveen K Yadav
  • Hui Xia Zhang
  • Rui Jin Wu
  • Chang qin Liu
  • Xiutian Guo
  • Min Cai
  • Li Hua Mo
  • Lu Zeng
  • Rong Ti Ge
  • Hai Qiong Yu
  • Lei Lei Fang
  • Bai Sui Feng
  • Chong He
  • Yang Song
  • Xiao Rong Xu
  • Stefaan Colpaert
  • Teng Fei Chen
  • Hui Min Chen
  • Fei Ke
  • Ji Chang Li
  • Philippe Maerten
  • Shu Man Liu
  • Shan shan Li
  • Feng hua Liu
  • Mao Gang Li
  • Rui Di Xie
  • Lin Jing Li
  • Huan Ping Zhang
  • Peng Yuan Zheng
  • Ling zhi Xu
  • Meng Li
  • Hao Yan
  • Jan L Ceuppens
  • Xiao Yue Feng
  • Jian Jie Li
  • Shuai Wang
  • Yu Jie Zhao
  • Jun Shan Wang
  • Yan Hong Shi
  • Yan Min Guo
  • Freddy Penninckx
  • Chang Qing Yang
  • Yan Wei Lin
  • Yao Zong Yuan
  • Ji Lin Wang
  • Xuan Kong
  • Hui Lin
  • Fei Liu
  • Jian Xin Wu
  • Jing Yuan Fang
  • Wei Hua Yu
  • Ya Nan Yu
  • Liu Zhan Ju
  • Praveen Kumar Yadav
  • Chi Chen
  • Xie Fu Zhang
  • Qing Meng
  • Sheng Dian Wang
  • Qin xian Zhang
  • Jan Ceuppens
  • Chong Shen
  • Kathleen Vanstraelen
  • Kathleen Vastraelen

Detail Information

Publications26

  1. ncbi Current strategies for the treatment of ulcerative colitis
    Praveen K Yadav
    Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Recent Pat Inflamm Allergy Drug Discov 3:65-72. 2009
    ..Additionally, colectomy may be required if medical treatments are unsuccessful or if complications develop. Some of the recent patent related to the field also discuss in this review article...
  2. doi Il-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease
    Zhanju Liu
    Department of Gastroenterology, Shanghai Tenth People s Hospital, Tongji University School of Medicine, Shanghai, China
    Inflamm Bowel Dis 15:1133-44. 2009
    ..Here we investigated IL-21 receptor (IL-21R) expression in inflamed mucosa of inflammatory bowel disease (IBD) and evaluated its role in the induction of NK cell cytotoxicity and activation as well as Th17 differentiation...
  3. pmc Herbal medicine in the treatment of ulcerative colitis
    Fei Ke
    Department of Gastroenterology, The Shanghai Tenth People s Hospital, Tongji University, No 301 Yanchang Road, Shanghai, China
    Saudi J Gastroenterol 18:3-10. 2012
    ..There is a need for further controlled clinical trials of the potential efficacy of herbal medicine approaches in the treatment of UC, together with enhanced legislation to maximize their quality and safety...
  4. pmc Potential role of NK cells in the pathogenesis of inflammatory bowel disease
    Praveen K Yadav
    Department of Gastroenterology, The Shanghai Tenth People s Hospital, Tongji University School of Medicine, Shanghai, China
    J Biomed Biotechnol 2011:348530. 2011
    ..g., IFN-╬│ and TNF) and promote the cytolytic activities against the target cells. This paper provides the characteristics of intestinal NK cells and their potential role in the pathogenesis of IBD...
  5. pmc Microbiota regulation of inflammatory bowel disease and colorectal cancer
    Zhanju Liu
    Department of Gastroenterology, The Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China Electronic address
    Semin Cancer Biol 23:543-52. 2013
    ..We will discuss the recent progress on how gut microbiota regulates intestinal homeostasis and the pathogenesis of inflammatory bowel disease and colorectal cancer. ..
  6. ncbi [Association between HLA-Cw polymorphism and inflammatory bowel disease]
    Hui Xia Zhang
    Department of Gastroenterology, Tongji University, Shanghai, China
    Zhonghua Nei Ke Za Zhi 50:856-8. 2011
    ..To investigate the association of HLA-Cw alleles with inflammatory bowel disease(IBD), so as to identify IBD susceptibility gene...
  7. pmc Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease
    Zhan Ju Liu
    Department of Gastroenterology, Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China
    World J Gastroenterol 15:5784-8. 2009
    ..The identification of Th17 cells helps us to explain some of the anomalies seen in the Th1/Th2 axis and has broadened our understanding of the immunopathological effects of Th17 cells in the development of IBD...
  8. doi The increased expression of IL-23 in inflammatory bowel disease promotes intraepithelial and lamina propria lymphocyte inflammatory responses and cytotoxicity
    Zhanju Liu
    Department of Gastroenterology, The Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China
    J Leukoc Biol 89:597-606. 2011
    ..Targeted therapy directed against IL-23p19 may have a therapeutic role in treatment of IBD...
  9. ncbi Blockage of tumor necrosis factor prevents intestinal mucosal inflammation through down-regulation of interleukin-23 secretion
    Zhanju Liu
    Laboratory of Immunopathology, Department of Gastroenterology, The Second Affiliated Hospital, Zhengzhou University, 2 Jingba Road, Zhengzhou 450014, China
    J Autoimmun 29:187-94. 2007
    ....
  10. ncbi Hyperamylasemia, reactive plasmacytosis, and immune abnormalities in a patient with celiac disease
    Zhanju Liu
    Laboratory of Immunopathology, The Institute of Digestive Diseases, Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Dig Dis Sci 52:1444-7. 2007
  11. pmc Specific immunotherapy ameliorates ulcerative colitis
    Min Cai
    Department of Gastroenterology, Shanghai Tenth People s Hospital of Tongji University, Shanghai, China
    Allergy Asthma Clin Immunol 12:37. 2016
    ..Hypersensitivity reaction to certain allergens plays a role in the pathogenesis of inflammatory bowel disease (IBD). This study aims to observe the effect of specific immunotherapy in a group of IBD patients...
  12. doi Interaction of TIM4 and TIM3 induces T helper 1 cell apoptosis
    Rong Ti Ge
    Department of Gastroenterology, The Shanghai Tenth People s Hospital of Tongji University, Shanghai, 200072, China
    Immunol Res 64:470-5. 2016
    ..In conclusion, TIM4 binds TIM3 on the surface of polarized Th1 cells to induce Th1 cell apoptosis, which may contribute to the development of Th2-dominant immune disorders. ..
  13. pmc Severe Henoch-Sch├Ânlein purpura with infliximab for ulcerative colitis
    Yang Song
    Yang Song, Yan Hong Shi, Chong He, Chang Qin Liu, Jun Shan Wang, Yu Jie Zhao, Yan Min Guo, Rui Jin Wu, Xiao Yue Feng, Zhan Ju Liu, Department of Gastroenterology, Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China
    World J Gastroenterol 21:6082-7. 2015
    ..Although the precise mechanisms of the vasculitis are still controversial, such a case highlights the importance of subcutaneous adverse effects in the management of UC with IFX. ..
  14. doi Thrombospondin 1 Modulates Monocyte Properties to Suppress Intestinal Mucosal Inflammation
    Lei Lei Fang
    Department of Gastroenterology, Shanghai Tenth People s Hospital of Tongji University, Shanghai, China
    J Innate Immun 7:601-11. 2015
    ..The results implicate that the administration of C. butyricum or butyrate may have the potential to ameliorate chronic intestinal inflammation through inducing immunosuppressive Mos. ..
  15. doi Decreased dietary fiber intake and structural alteration of gut microbiota in patients with advanced colorectal adenoma
    Hui Min Chen
    Division of Gastroenterology and Hepatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institution of Digestive Disease, Shanghai, China
    Am J Clin Nutr 97:1044-52. 2013
    ..Accumulating evidence indicates that diet is one of the most important environmental factors involved in the progression from advanced colorectal adenoma (A-CRA) to colorectal cancer...
  16. ncbi [Relationship between expression of inhibitory killer cell immunoglobulin-like receptor HLA-Cw ligand and susceptibility to inflammatory bowel disease]
    Hui Xia Zhang
    Department of Gastroenterology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
    Zhonghua Yi Xue Za Zhi 88:3108-11. 2008
    ....
  17. doi All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis
    Aiping Bai
    Department of Gastroenterology, The First Affiliated Hospital, Nanchang University, Nanchang 330006, China
    J Leukoc Biol 86:959-69. 2009
    ..RA down-regulates colon inflammatory responses in patients with IBD in vitro and in murine colitis in vivo, representing a potential therapeutic approach in IBD treatment...
  18. doi Tumor necrosis factor suppresses interleukin 10 in peripheral B cells via upregulating Bcl2-like protein 12 in patients with inflammatory bowel disease
    Xiutian Guo
    Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Cell Biochem Funct . 2017
    ..In conclusion, Bcl2L12 mediates the effects of TNF to suppress the expression of IL-10 in B cells. The data suggest that Bcl2L12 may be a therapeutic target for the treatment of IBD...
  19. pmc Dysregulation of mucosal immune response in pathogenesis of inflammatory bowel disease
    Xiao Rong Xu
    Xiao Rong Xu, Chang Qin Liu, Bai Sui Feng, Zhan Ju Liu, Department of Gastroenterology, Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China
    World J Gastroenterol 20:3255-64. 2014
    ..Studying the interactions between various constituents of the innate and adaptive immune systems will certainly open new horizons of the knowledge about the immunologic mechanisms in IBD...
  20. pmc Comparative evaluation of intragastric bile acids and hepatobiliary scintigraphy in the diagnosis of duodenogastric reflux
    Teng Fei Chen
    Department of Gastroenterology, Shanghai Tenth People s Hospital, Tongji University, Shanghai 200072, China
    World J Gastroenterol 19:2187-96. 2013
    ..To assess the diagnostic value of a combination of intragastric bile acids and hepatobiliary scintigraphy in the detection of duodenogastric reflux (DGR)...
  21. ncbi [Expression and significance of B7-H1 and its receptor PD-1 in human gastric carcinoma]
    Shu Man Liu
    Department of Histology and Embryology, College of Medicine, Zhengzhou University, Zhengzhou 450052, China
    Zhonghua Zhong Liu Za Zhi 30:192-5. 2008
    ..The aim of this study was to examine the B7-H1 and PD-1 expression and TILs status in gastric cancer and to elucidate the clinical relevance of B7-H1 and PD-1 to the pathogenesis of gastric carcinoma...
  22. ncbi Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma
    Peter W Hellings
    Laboratory of Experimental Immunology, Rega Institute, University of Leuven, Leuven, Belgium
    Am J Respir Cell Mol Biol 28:42-50. 2003
    ..Because neutrophils may be important in airway remodeling in chronic severe asthma, targeting IL-17 may hold therapeutic potential in human asthma...
  23. ncbi In vitro analysis of interferon gamma (IFN-gamma) and interleukin-12 (IL-12) production and their effects in ileal Crohn's disease
    Stefaan Colpaert
    Laboratory of Experimental Immunology, University Hospital Gasthuisberg and Catholic University of Leuven, Belgium
    Eur Cytokine Netw 13:431-7. 2002
    ..Therapies aiming at neutralisation of IFN-gamma or IL-12 are therefore unlikely to replace anti-TNF, but they might provide an additive or synergistic effect...
  24. ncbi Targeting of costimulatory molecules as a therapeutic approach in inflammatory bowel disease
    Philippe Maerten
    Division of Clinical Immunology and Gastroenterology, University Hospital of Leuven, Leuven, Belgium
    BioDrugs 17:395-411. 2003
    ....
  25. ncbi Intestinal epithelial antigen induces mucosal CD8 T cell tolerance, activation, and inflammatory response
    Zhanju Liu
    Division of Immunology, University of Connecticut Health Center, Farmington, CT 06030, USA
    J Immunol 173:4324-30. 2004
    ..However, when Ag is presented in the context of bacterial infection, the associated inflammatory signals drive Ag-specific CD8(+) T cells to mediate intestinal immunopathology...
  26. ncbi Decreased lamina propria effector cell responsiveness to interleukin-10 in ileal Crohn's disease
    Stefaan Colpaert
    Laboratory of Experimental Immunology, University Hospital and Katholieke Universiteit Leuven, Leuven, Belgium
    Clin Immunol 102:68-76. 2002
    ..We conclude that IL-10 exhibits poor anti- and even potential proinflammatory effects on ileal Crohn's disease lamina propria. These data might explain the lack of therapeutic efficacy when IL-10 is given to Crohn's disease patients...