Yiyao Liu

Summary

Publications

  1. doi request reprint Protein receptor for activated C kinase 1 is involved in morphine reward in mice
    L Wan
    Key Laboratory of Chronobiology, Ministry of Health Sichuan University, Sichuan University, Chengdu, Sichuan, PR China
    Neuroscience 161:734-42. 2009
  2. pmc The roles of platelet GPIIb/IIIa and alphavbeta3 integrins during HeLa cells adhesion, migration, and invasion to monolayer endothelium under static and dynamic shear flow
    Yiyao Liu
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China
    J Biomed Biotechnol 2009:829243. 2009
  3. doi request reprint [Detection of CEA mRNA on non-small lung cancer and it's significance.]
    Guowen Wang
    Department of Cardiothoracic Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China
    Zhongguo Fei Ai Za Zhi 11:719-23. 2008
  4. doi request reprint Core/shell Fe3O4 @SiO2 nanoparticles modified with PAH as a vector for EGFP plasmid DNA delivery into HeLa cells
    Mengran Shi
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, China
    Macromol Biosci 11:1563-9. 2011
  5. ncbi request reprint Multifunctional nanoparticles of Fe(3)O(4)@SiO(2)(FITC)/PAH conjugated the recombinant plasmid of pIRSE2-EGFP/VEGF(165) with dual functions for gene delivery and cellular imaging
    Yiyao Liu
    University of Electronic Science and Technology of China, School of Life Science and Technology, Department of Biophysics, Chengdu 610054, Sichuan, P R China
    Expert Opin Drug Deliv 9:1197-207. 2012
  6. ncbi request reprint Encapsulated ultrasound microbubbles: therapeutic application in drug/gene delivery
    Yiyao Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan Province, PR China
    J Control Release 114:89-99. 2006
  7. ncbi request reprint Effects of vascular endothelial growth factor (VEGF) and chondroitin sulfate A on human monocytic THP-1 cell migration
    Y Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, PR China
    Colloids Surf B Biointerfaces 43:216-20. 2005
  8. ncbi request reprint Effect of ultrasonic exposure on Ca2+-ATPase activity in plasma membrane from Aloe arborescens callus cells
    Yiyao Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, PR China
    Ultrason Sonochem 13:232-6. 2006
  9. ncbi request reprint Ultrasound: mechanical gene transfer into plant cells by sonoporation
    Y Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu
    Biotechnol Adv 24:1-16. 2006
  10. ncbi request reprint Influence of parenteral fat emulsion Intralipos and citric acid on blood viscosity and erythrocyte morphology in vitro
    Yiyao Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan Province, PR China
    Colloids Surf B Biointerfaces 53:51-4. 2006

Collaborators

  • Hong Yang
  • Li Li
  • Zhishun Wang
  • Wang Zhiping
  • Y Wang
  • Jing Zhang
  • Chonghua Wan
  • Yu Chen
  • Dan Li
  • Lena Sun
  • Xitong Dang
  • Ying Li
  • Chunhui Wu
  • Shun Li
  • Tingting Li
  • Hongjuan Zeng
  • Niya Xiong
  • Y Yang
  • J Li
  • R L Hu
  • Fenglong Zhao
  • H Hua
  • Mengran Shi
  • Y S Guan
  • Min Wu
  • Xue Shen
  • Anni Zhu
  • Xiaoyan Xiong
  • Z Jiang
  • Guoquan Meng
  • M Ma
  • L Lin
  • D Tao
  • L Wan
  • H Guo
  • J Xiao
  • G Q Ren
  • X Peng
  • Y Ma
  • S Zhang
  • Guowen Wang
  • Y Zou
  • L Yan
  • S Li
  • A R Fooks
  • F Zhang
  • S F Zhang
  • X Li
  • J Yao
  • E H Wang
  • Yueting Peng
  • Hongxia Bai
  • Kai Tang
  • Lianhui Wang
  • Xue Zhao
  • Zhongyuan Chen
  • Sugang Peng
  • Yue Geng
  • Juan Lu
  • Ruolan Bai
  • Lilan Chen
  • Wei Liao
  • Jie Yan
  • Hongjun Zeng
  • Chengchen Zhang
  • Qiuming He
  • Min Xu
  • Liuyuan Guan
  • H Bai
  • Hirokazu Miyoshi
  • Mingming Xu
  • W Li
  • Z Zhao
  • J Liu
  • F Halberg
  • P Chen
  • N Huang
  • J Ge
  • T Yang
  • D Long
  • G Cornelissen
  • J Wang
  • Changchun Lou
  • D Su
  • C Xia
  • L Su
  • D Yu
  • T Li
  • Y Xie
  • E Xia

Detail Information

Publications58

  1. doi request reprint Protein receptor for activated C kinase 1 is involved in morphine reward in mice
    L Wan
    Key Laboratory of Chronobiology, Ministry of Health Sichuan University, Sichuan University, Chengdu, Sichuan, PR China
    Neuroscience 161:734-42. 2009
    ..These findings suggest that morphine reward can influence the expression of RACK1 in mouse hippocampus and prefrontal cortex through regulating CREB transcription...
  2. pmc The roles of platelet GPIIb/IIIa and alphavbeta3 integrins during HeLa cells adhesion, migration, and invasion to monolayer endothelium under static and dynamic shear flow
    Yiyao Liu
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China
    J Biomed Biotechnol 2009:829243. 2009
    ....
  3. doi request reprint [Detection of CEA mRNA on non-small lung cancer and it's significance.]
    Guowen Wang
    Department of Cardiothoracic Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China
    Zhongguo Fei Ai Za Zhi 11:719-23. 2008
    ....
  4. doi request reprint Core/shell Fe3O4 @SiO2 nanoparticles modified with PAH as a vector for EGFP plasmid DNA delivery into HeLa cells
    Mengran Shi
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, China
    Macromol Biosci 11:1563-9. 2011
    ..Thus, Fe(3)O(4)@SiO(2)/PAH nanoparticles are biocompatible and suitable for nonviral delivery, and may find applications in cancer therapy...
  5. ncbi request reprint Multifunctional nanoparticles of Fe(3)O(4)@SiO(2)(FITC)/PAH conjugated the recombinant plasmid of pIRSE2-EGFP/VEGF(165) with dual functions for gene delivery and cellular imaging
    Yiyao Liu
    University of Electronic Science and Technology of China, School of Life Science and Technology, Department of Biophysics, Chengdu 610054, Sichuan, P R China
    Expert Opin Drug Deliv 9:1197-207. 2012
    ..However, effective transport of VEGF gene to target cells with minimal side effects remains a challenge despite the use of unique viral and non-viral delivery approaches...
  6. ncbi request reprint Encapsulated ultrasound microbubbles: therapeutic application in drug/gene delivery
    Yiyao Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan Province, PR China
    J Control Release 114:89-99. 2006
    ..In this paper, the characterization of novel targeted ultrasonic contrast agents or microbubbles and their potential applications in drug delivery or gene therapy are reviewed...
  7. ncbi request reprint Effects of vascular endothelial growth factor (VEGF) and chondroitin sulfate A on human monocytic THP-1 cell migration
    Y Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, PR China
    Colloids Surf B Biointerfaces 43:216-20. 2005
    ..Our results demonstrated that VEGF accelerated monocyte migration through endothelial monolayer and chondroitin sulfate A is an effective inhibitor of monocyte migration for angiogenesis...
  8. ncbi request reprint Effect of ultrasonic exposure on Ca2+-ATPase activity in plasma membrane from Aloe arborescens callus cells
    Yiyao Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, PR China
    Ultrason Sonochem 13:232-6. 2006
    ..Our results showed that low-energy ultrasound exposure was a useful physical field to stimulate A. arborescens callus cells to adapt environmental stress through PM Ca2+-ATPase activity increase...
  9. ncbi request reprint Ultrasound: mechanical gene transfer into plant cells by sonoporation
    Y Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu
    Biotechnol Adv 24:1-16. 2006
    ..Recently, most researches are focused on sonication-assisted Agrobacterium-mediated transformation (SAAT) in plant cells or tissues. Microbubbles are also proposed to apply to gene transfer in plant cells and tissues...
  10. ncbi request reprint Influence of parenteral fat emulsion Intralipos and citric acid on blood viscosity and erythrocyte morphology in vitro
    Yiyao Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan Province, PR China
    Colloids Surf B Biointerfaces 53:51-4. 2006
    ..We concluded that the intravenous soybean-oil preparation Intralipos interacts with the erythrocyte membrane, and citric acid could alleviate the whole blood viscosity...
  11. ncbi request reprint Nanomedicine for drug delivery and imaging: a promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles
    Yiyao Liu
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, People s Republic of China
    Int J Cancer 120:2527-37. 2007
    ..In this article, we review the significance and recent advances of gene/drug delivery to cancer cells, and the molecular imaging and diagnosis of cancer by targeted functional nanoparticles...
  12. ncbi request reprint Novel drug delivery system of hollow mesoporous silica nanocapsules with thin shells: preparation and fluorescein isothiocyanate (FITC) release kinetics
    Yiyao Liu
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan 610054, PR China
    Colloids Surf B Biointerfaces 58:180-7. 2007
    ....
  13. ncbi request reprint Silica nanoparticles as promising drug/gene delivery carriers and fluorescent nano-probes: recent advances
    Yiyao Liu
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, P R China
    Curr Cancer Drug Targets 11:156-63. 2011
    ....
  14. doi request reprint MCP-1-induced ERK/GSK-3β/Snail signaling facilitates the epithelial-mesenchymal transition and promotes the migration of MCF-7 human breast carcinoma cells
    Shun Li
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, China
    Cell Mol Immunol . 2016
    ..Cellular & Molecular Immunology advance online publication, 21 March 2016; doi:10.1038/cmi.2015.106...
  15. pmc VCAM-1-targeted core/shell nanoparticles for selective adhesion and delivery to endothelial cells with lipopolysaccharide-induced inflammation under shear flow and cellular magnetic resonance imaging in vitro
    Hong Yang
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, People s Republic of China
    Int J Nanomedicine 8:1897-906. 2013
    ....
  16. doi request reprint Roles for GP IIb/IIIa and αvβ3 integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction
    Fenglong Zhao
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China
    Cancer Lett 344:62-73. 2014
    ....
  17. doi request reprint Folate-Functionalized Magnetic-Mesoporous Silica Nanoparticles for Drug/Gene Codelivery To Potentiate the Antitumor Efficacy
    Tingting Li
    Department of Biophysics, School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, People s Republic of China
    ACS Appl Mater Interfaces 8:13748-58. 2016
    ..The approach provides a potential strategy to treat cancer by a singular nanoparticle delivery system. ..
  18. pmc Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo
    Hong Yang
    Department of Biophysics, School of Life Science and Technology of China, Chengdu 610054, Sichuan, P R China
    Oncotarget 7:16227-47. 2016
    ..Our findings highlight the importance of Cav-1 in hematogenous metastasis, and provide new insights into the underlying mechanisms of mechanotransduction induced by LSS. ..
  19. doi request reprint Notch-1 signaling activates NF-κB in human breast carcinoma MDA-MB-231 cells via PP2A-dependent AKT pathway
    Li Li
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, Sichuan, People s Republic of China
    Med Oncol 33:33. 2016
    ..Taken together, our results suggest that Notch-1-activating PI3K/AKT/NF-κB pathway is PP2A dependent; PP2A may be a potential therapeutic target in breast cancer. ..
  20. doi request reprint Polymeric microbubbles for ultrasonic molecular imaging and targeted therapeutics
    Xiaoyan Xiong
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China
    J Biomater Sci Polym Ed 22:417-28. 2011
    ..In this review, we highlight some of the recent examples on polymeric microbubbles and their applications in ultrasound molecular imaging and drug delivery...
  21. pmc Investigation of folate-conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism
    Hong Yang
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, People s Republic of China
    Int J Nanomedicine 6:2023-32. 2011
    ..These results demonstrated that the novel particles of NPs(FITC)-PEG-Folate are promising for fluorescent imaging or targeting delivery to folate receptor-positive tumors...
  22. pmc Adhesion of bio-functionalized ultrasound microbubbles to endothelial cells by targeting to vascular cell adhesion molecule-1 under shear flow
    Hong Yang
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan
    Int J Nanomedicine 6:2043-51. 2011
    ..These findings showed that the specific ligand-carrying microbubbles have considerable potential in targeted ultrasound molecular imaging or ultrasound-assisted drug/gene delivery applications...
  23. doi request reprint Involvement of caveolin-1 in low shear stress-induced breast cancer cell motility and adhesion: Roles of FAK/Src and ROCK/p-MLC pathways
    Niya Xiong
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, PR China
    Biochim Biophys Acta 1864:12-22. 2017
    ....
  24. doi request reprint Photosensitizer-assembled PEGylated graphene-copper sulfide nanohybrids as a synergistic near-infrared phototherapeutic agent
    Chunhui Wu
    a Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, P R China
    Expert Opin Drug Deliv 13:155-65. 2016
    ....
  25. pmc Polyetherimide-grafted Fe₃O₄@SiO2₂ nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging
    Tingting Li
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, People s Republic of China
    Int J Nanomedicine 10:4279-91. 2015
    ....
  26. pmc Multifunctional core/shell nanoparticles cross-linked polyetherimide-folic acid as efficient Notch-1 siRNA carrier for targeted killing of breast cancer
    Hong Yang
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, Sichuan, P R China
    Sci Rep 4:7072. 2014
    ....
  27. pmc Notch-1 signaling promotes the malignant features of human breast cancer through NF-κB activation
    Li Li
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, P R China
    PLoS ONE 9:e95912. 2014
    ..Our results further suggest that targeting Notch-1 signaling pathway may become a newer approach to halt the progression of breast cancer. ..
  28. ncbi request reprint A comparison of oestrogen receptor and progesterone receptor expression in endometrial polyps and endometrium of premenopausal women
    X Peng
    Hysteroscopic Centre, Fuxing Hospital, Capital Medical University, Beijing, People s Republic of China
    J Obstet Gynaecol 29:340-6. 2009
    ..The results suggest that abnormal expression of hormone receptor contribute to endometrial polyps formation...
  29. doi request reprint Phonological activation in chinese reading: an event-related potential study using low-resolution electromagnetic tomography
    G Q Ren
    Department of Psychology, Liaoning Normal University, Dalian 116029, China
    Neuroscience 164:1623-31. 2009
    ..These findings suggest that phonology is activated automatically for both high- and low-frequency words during Chinese sentence reading, even when the task is not focused on pronunciation...
  30. ncbi request reprint A cardiopulmonary bypass perfusion technique for the surgical repair of aortic type I dissections requiring the elephant trunk procedure
    T Yang
    Department of Cardiopulmonary Bypass and Cardiac Surgery, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing
    J Extra Corpor Technol 32:220-3. 2000
    ..All patients survived the operation and were discharged from the hospital. This modified perfusion technique of SCP and LBP worked well and provided satisfactory cerebral and spinal cord protection...
  31. ncbi request reprint Studies on the growth metabolism of Bacillus thuringiensis and its vegetative insecticidal protein engineered strains by microcalorimetry
    J Yao
    College of Chemistry and Molecular Science, Wuhan University, Hubai, P R China
    Prikl Biokhim Mikrobiol 42:310-4. 2006
    ..The determination of the thermokinetic character is beneficial to the control of fermentation...
  32. ncbi request reprint Protein serine/threonine phosphatase-1 dephosphorylates p53 at Ser-15 and Ser-37 to modulate its transcriptional and apoptotic activities
    D W C Li
    The Hormel Institute, University of Minnesota, Austin, 55912, USA
    Oncogene 25:3006-22. 2006
    ..In addition, our results reveal that one of the molecular mechanisms by which PP-1 promotes cell survival is to dephosphorylate p53, and thus negatively regulate p53-dependent death pathway...
  33. ncbi request reprint Sequences variations in 5'-flanking region of ABO gene and correlation with ABO alleles in the indigenous Chinese
    L Yan
    Institute of Transfusion Medicine, Blood Center of Zhejiang Province, Hangzhou, Zhejiang 310006, China
    Vox Sang 94:227-33. 2008
    ..Here, we further characterize the molecular genetic basis and ABO allele-related polymorphism of the 5'-untranslated regions (5'-UTR) of the human ABO gene...
  34. ncbi request reprint New management of angle-closure glaucoma by phacoemulsification with foldable posterior chamber intraocular lens implantation
    J Ge
    Zhongshan Ophthalmic Center, Sun Yat Sen University of Medical Sciences, Guangzhou 510060, China
    Yan Ke Xue Bao 16:22-8. 2000
    ..To investigate the management of angle-closure glaucoma by phacoemulsification with foldable posterior chamber intraocular lens (PC-IOL) implantation...
  35. ncbi request reprint Experimental immunization of cats with a recombinant rabies-canine adenovirus vaccine elicits a long-lasting neutralizing antibody response against rabies
    R L Hu
    Laboratory of Epidemiology, Veterinary Institute, Academy of Military Medical Sciences, 1068 Qinglong Road, Changchun 130062, PR China
    Vaccine 25:5301-7. 2007
    ....
  36. ncbi request reprint Surgical treatment of DeBakey type I aortic dissection using the "elephant trunk technique"
    L Sun
    Department of Cardiac Surgery, Cardiovascular Institute, Fu Wai Hospital, CAMS, PUMC, Beijing 100037, China
    Chin Med J (Engl) 112:713-6. 1999
    ..To review the indications, operative methods and postoperative management of the "elephant trunk technique", and to report two cases of DeBakey type I aortic dissection treated with the "elephant trunk technique"...
  37. ncbi request reprint Microtubule-associated protein-2: a new sensitive and specific marker for pulmonary carcinoid tumor and small cell carcinoma
    Y Liu
    Department of Pathology and Laboratory Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA
    Mod Pathol 14:880-5. 2001
    ..We recommend that MAP-2 be added to immunohistochemical panels to separate non-neuroendocrine from neuroendocrine lung tumors...
  38. pmc Inferior rabies vaccine quality and low immunization coverage in dogs ( Canis familiaris) in China
    R L Hu
    Laboratory of Epidemiology, Veterinary Institute, Academy of Military Medical Sciences, Changchun, China
    Epidemiol Infect 136:1556-63. 2008
    ..These data suggest that the factors noted above are highly correlated with the high incidence of human rabies in China...
  39. doi request reprint Brainstem and thalamic projections from a craniovascular sensory nervous centre in the rostral cervical spinal dorsal horn of rats
    Y Liu
    Department of Clinical Science, Experimental Vascular Research, Lund University, Lund, Denmark
    Cephalalgia 29:935-48. 2009
    ..Some of the above regions are likely to be involved in the central processing of noxious signals of craniovascular origin and therefore putatively involved in mechanisms associated with primary headaches...
  40. ncbi request reprint Relative androgen excess and increased cardiovascular risk after menopause: a hypothesized relation
    Y Liu
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Am J Epidemiol 154:489-94. 2001
    ....
  41. ncbi request reprint Abnormal expression and clinicopathologic significance of p120-catenin in lung cancer
    E H Wang
    Department of Pathology, College of Basic Medical Sciences, China Medical University, Shenyang, China
    Histol Histopathol 21:841-7. 2006
    ..Reduced expression or even the absence of p120ctn isoform 1 and 3 in tumor cell membranes may be responsible for the abnormal expression of p120ctn that has been found in lung cancer...
  42. doi request reprint Essential oils from Inula japonica and Angelicae dahuricae enhance sensitivity of MCF-7/ADR breast cancer cells to doxorubicin via multiple mechanisms
    Min Wu
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, PR China Department of Pharmacy, Chengdu Medical College, Chengdu 610081, Sichuan, PR China Electronic address
    J Ethnopharmacol 180:18-27. 2016
    ..These findings suggest the possibility that essential oils may enhance the absorption via certain mechanisms related to ABCB1 and reverse multidrug resistance (MDR)...
  43. pmc Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition
    Shun Li
    Department of Biophysics, School of Life Science and Technology
    Sci Rep 5:12410. 2015
    ..These results indicate that TEPA inhibits CoCl2-induced EMT most likely via HIF1-α-Snail/Twist signaling pathway, and copper depletion may be exploited as a therapeutic for breast cancer. ..
  44. doi request reprint Synergistic anticancer activity of photo- and chemoresponsive nanoformulation based on polylysine-functionalized graphene
    Chunhui Wu
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan 610054, P R China
    ACS Appl Mater Interfaces 6:21615-23. 2014
    ..1) against three cancer cell lines tested (HeLa, MCF-7, and B16). Thus, this study demonstrates programmable dual-modality therapy exemplified by G-PLL/DOX/ZnPc to synergistically treat cancers...
  45. pmc Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells
    Guoquan Meng
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan, China
    Br J Pharmacol 161:1628-44. 2010
    ..The present study was designed to explore the molecular target(s) of emodin in modifying lipopolysaccharide (LPS)-associated signal transduction pathways in endothelial cells...
  46. ncbi request reprint Poly(D,L-lactide-co-glycolide) nanoparticles encapsulated fluorescent isothiocyanate and paclitaxol: preparation, release kinetics and anticancer effect
    Hong Yang
    Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, Sichuan 610054, PR China
    J Nanosci Nanotechnol 9:282-7. 2009
    ....
  47. ncbi request reprint Association of the 54-nucleotide repeat polymorphism of hPer3 with heroin dependence in Han Chinese population
    Y Zou
    Health Ministry Key Lab of Chronobiology, West China Medical Center, Sichuan University, Sichuan, China
    Genes Brain Behav 7:26-30. 2008
    ..Our results suggest that the 54-nucleotide repeat polymorphism of hPer3 significantly associates with heroin dependence at the allele frequency level and may be a potential risk factor for the development of heroin dependence...
  48. ncbi request reprint Relationship between the regulatory region polymorphism of human tissue kallikrein gene and essential hypertension
    H Hua
    1School of Basic Medicine and Forensic, West China Medical Center, Sichuan University, Chengdu, Sichuan, PR China
    J Hum Hypertens 19:715-21. 2005
    ..Differences in both allele frequencies and genotype frequencies between these two groups have provided evidence towards the association of hypertension with the polymorphisms in this studied site...
  49. ncbi request reprint Evidence for the association of Y-chromosome haplogroups with susceptibility to spermatogenic failure in a Chinese Han population
    Y Yang
    Department of Medical Genetics and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, P R China
    J Med Genet 45:210-5. 2008
    ....
  50. doi request reprint Circadian blood pressure and heart rate characteristics in haemorrhagic vs ischaemic stroke in Chinese people
    Z Jiang
    Key Laboratory of Chronobiology, Ministry of Health Sichuan University, Sichuan University, Chengdu, Sichuan, PR China
    J Hum Hypertens 24:165-74. 2010
    ....
  51. pmc p53 gene (Gendicine) and embolisation overcame recurrent hepatocellular carcinoma
    Y S Guan
    Department of Radiology, West China Hospital, Sichuan University, 37 Guoxuexiang, Chengdu 610041, Sichuan Province, China
    Gut 54:1318-9. 2005
    ..In this study, we report a 23 year old patient with recurrent HCC who was treated with the p53 gene (Gendicine) combining TACE, which resulted in a good clinical prognosis...
  52. ncbi request reprint Improvement of insulin sensitivity and beta-cell function by nateglinide and repaglinide in type 2 diabetic patients - a randomized controlled double-blind and double-dummy multicentre clinical trial
    J Li
    Department of Endocrinology, State Key Lab of Biotherapy, West China Hospital of Sichuan University, Chengdu, China
    Diabetes Obes Metab 9:558-65. 2007
    ..To evaluate the efficacy of nateglinide vs. repaglinide in blood glucose (BG) control and the effect on insulin resistance and beta-Cell function in patients with type 2 diabetes...
  53. ncbi request reprint [Analysis of apoA IV gene VNTR polymorphism in Chinese endogenous hypertriglyceridemics]
    H Bai
    Apolipoprotein Research Unit, West China University of Medical Sciences, Chengdu, Sichuan, 610041 P R China
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 18:356-61. 2001
    ..To search the variation of apoA IV gene and its relation to endogenous hypertriglyceridemia (HTG) in Chinese population...
  54. doi request reprint Differential effect of specific gr/gr deletion subtypes on spermatogenesis in the Chinese Han population
    Y Yang
    Department of Medical Genetics, West China Hospital, West China Medical School, and State Key Laboratory of Biotherapy, Sichuan University, Sichuan, China
    Int J Androl 33:745-54. 2010
    ....
  55. doi request reprint MEK/ERK and p38 MAPK regulate chondrogenesis of rat bone marrow mesenchymal stem cells through delicate interaction with TGF-beta1/Smads pathway
    J Li
    State Key Laboratory of Oral Diseases, West China College of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, China
    Cell Prolif 43:333-43. 2010
    ....
  56. pmc Tracheal-oesophageal fistula in a patient with lung cancer
    Y S Guan
    Department of Radiology, West China Hospital, Sichuan University, 37 Guoxuexiang Street, Chengdu 610041, Sichuan Province, China
    Gut 55:1295, 1305. 2006
  57. ncbi request reprint Inhibition of tumorigenesis by intratumoral delivery of the circadian gene mPer2 in C57BL/6 mice
    H Hua
    Laboratory of Molecular Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan, China
    Cancer Gene Ther 14:815-8. 2007
    ..These findings underscore the potential use of Per2 gene delivery as a novel therapeutic intervention for the treatment of malignant tumors...
  58. ncbi request reprint Separation, cultivation and biological characteristics of oral carcinoma-associated fibroblasts
    Y Liu
    Department of Oral Medicine, West China College of Stomatology, Sichuan University, Chengdu, China
    Oral Dis 12:375-80. 2006
    ..The aim of the study was to separate, cultivate, identify oral CAFs, and to investigate their biological characteristics...