Xiuli Liu

Summary

Publications

  1. doi request reprint Collagenous colitis in children and adolescents: study of 7 cases and literature review
    Xiuli Liu
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Mod Pathol 26:881-7. 2013
  2. ncbi request reprint The role of calpain in oncotic cell death
    Xiuli Liu
    Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Annu Rev Pharmacol Toxicol 44:349-70. 2004
  3. doi request reprint Gene expression profiling of serrated polyps identifies annexin A10 as a marker of a sessile serrated adenoma/polyp
    David Hernandez Gonzalo
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH 44195, USA
    J Pathol 230:420-9. 2013
  4. doi request reprint Crohn's disease-like reaction predicts favorable prognosis in colitis-associated colorectal cancer
    Brian Lewis
    Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA
    Inflamm Bowel Dis 19:2190-8. 2013
  5. doi request reprint Diagnostic utility of TP53 and cytokeratin 7 immunohistochemistry in idiopathic inflammatory bowel disease-associated neoplasia
    Hao Xie
    1 Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA 2 Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA
    Mod Pathol 27:303-13. 2014
  6. doi request reprint Semiquantitative histologic evaluation improves diagnosis of esophageal carcinoma cuniculatum on biopsy
    Derrick Chen
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Mod Pathol 26:806-15. 2013
  7. pmc Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury
    Sanjoy Roychowdhury
    Departments of Pathobiology, Center for Liver Disease Research, Cleveland Clinic, Cleveland, OH, USA
    Hepatology 57:1773-83. 2013
  8. doi request reprint Intramucosal esophageal adenocarcinoma: primum non nocere
    Zhigang Li
    Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 145:1519-24, 1524.e1-3. 2013
  9. ncbi request reprint Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death
    Xiuli Liu
    Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    J Pharmacol Exp Ther 304:63-70. 2003
  10. doi request reprint Risk for colorectal neoplasia in patients with inflammatory bowel disease and mucosa indefinite for dysplasia
    Keith K Lai
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio and Departments of Colorectal Surgery, and Gastroenterology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio
    Inflamm Bowel Dis 21:378-84. 2015

Detail Information

Publications52

  1. doi request reprint Collagenous colitis in children and adolescents: study of 7 cases and literature review
    Xiuli Liu
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Mod Pathol 26:881-7. 2013
    ..Treatment is less standardized in children and adolescents with CC...
  2. ncbi request reprint The role of calpain in oncotic cell death
    Xiuli Liu
    Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Annu Rev Pharmacol Toxicol 44:349-70. 2004
    ....
  3. doi request reprint Gene expression profiling of serrated polyps identifies annexin A10 as a marker of a sessile serrated adenoma/polyp
    David Hernandez Gonzalo
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH 44195, USA
    J Pathol 230:420-9. 2013
    ..Expression of ANXA10 may be a potential marker of the serrated pathway to colon cancer...
  4. doi request reprint Crohn's disease-like reaction predicts favorable prognosis in colitis-associated colorectal cancer
    Brian Lewis
    Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA
    Inflamm Bowel Dis 19:2190-8. 2013
    ..The aim of this study is to determine if clinicodemographics and tumor histomorphologic features are prognostic in patients with CAC...
  5. doi request reprint Diagnostic utility of TP53 and cytokeratin 7 immunohistochemistry in idiopathic inflammatory bowel disease-associated neoplasia
    Hao Xie
    1 Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA 2 Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA
    Mod Pathol 27:303-13. 2014
    ..Our results suggested that a combination of CK7 and TP53 immunohistochemistry may be helpful in diagnosing inflammatory bowel disease-associated dysplasia in difficult cases. ..
  6. doi request reprint Semiquantitative histologic evaluation improves diagnosis of esophageal carcinoma cuniculatum on biopsy
    Derrick Chen
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Mod Pathol 26:806-15. 2013
    ..Larger studies are necessary to confirm the current findings...
  7. pmc Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury
    Sanjoy Roychowdhury
    Departments of Pathobiology, Center for Liver Disease Research, Cleveland Clinic, Cleveland, OH, USA
    Hepatology 57:1773-83. 2013
    ..Ethanol-induced apoptosis, assessed by terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling-positive nuclei and accumulation of cytokeratin-18 fragments in the liver, was independent of RIP3...
  8. doi request reprint Intramucosal esophageal adenocarcinoma: primum non nocere
    Zhigang Li
    Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 145:1519-24, 1524.e1-3. 2013
    ..Less-invasive therapies have emerged, necessitating review of safety, effectiveness, and determinants of long-term outcome after esophagectomy to clarify the role of this traditional, maximally invasive, and potentially harmful therapy...
  9. ncbi request reprint Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death
    Xiuli Liu
    Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    J Pharmacol Exp Ther 304:63-70. 2003
    ..These results suggest that calpain mediates increased plasma membrane permeability and hydrolysis of cytoskeleton-associated paxillin, vinculin, and talin during renal cell death...
  10. doi request reprint Risk for colorectal neoplasia in patients with inflammatory bowel disease and mucosa indefinite for dysplasia
    Keith K Lai
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio and Departments of Colorectal Surgery, and Gastroenterology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio
    Inflamm Bowel Dis 21:378-84. 2015
    ..The management of colonic epithelial changes indefinite for dysplasia (IND) in patients with inflammatory bowel disease (IBD) remains controversial because of a paucity of published outcome data...
  11. doi request reprint Reproducibility of the villous component and high-grade dysplasia in colorectal adenomas <1 cm: implications for endoscopic surveillance
    Dipti Mahajan
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Am J Surg Pathol 37:427-33. 2013
    ..Interobserver agreement before and after the consensus conference was poor for assessment of A-VC, HGD, and AA. These data calls into question the validity of basing clinical decisions on this distinction...
  12. doi request reprint Serrated lesions of the appendix frequently harbor KRAS mutations and not BRAF mutations indicating a distinctly different serrated neoplastic pathway in the appendix
    Rish K Pai
    Department of Pathology, Cleveland Clinic, Cleveland, OH 44195, USA
    Hum Pathol 45:227-35. 2014
    ..Our results indicate that serrated lesions of the appendix often harbor KRAS mutations rather than BRAF mutations and suggest that the serrated pathway in the appendix is likely different than in the colon and rectum. ..
  13. doi request reprint Predictive and prognostic roles of ribonucleotide reductase M1 in resectable pancreatic adenocarcinoma
    Hao Xie
    Department of Anatomic Pathology, The Cleveland Clinic, Ohio, USA
    Cancer 119:173-81. 2013
    ..The objective of this study was to evaluate the predictive roles of RRM1 in the survival of patients with resectable pancreatic adenocarcinoma who received treatment with gemcitabine or nongemcitabine adjuvant therapy...
  14. pmc Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center
    Brandie Heald
    Cleveland Clinic, Cleveland, OH 44195, USA
    J Clin Oncol 31:1336-40. 2013
    ..No studies report how this process is implemented on a health system-wide basis...
  15. doi request reprint Morphologic and molecular characterization of traditional serrated adenomas of the distal colon and rectum
    Homer O Wiland
    Departments of Anatomic Pathology Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH
    Am J Surg Pathol 38:1290-7. 2014
    ..However, ectopic crypt foci, a proposed defining feature of TSA, were not associated with any specific molecular alteration. ..
  16. doi request reprint Endometriosis involving the mucosa of the intestinal tract: a clinicopathologic study of 15 cases
    Wei Jiang
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Mod Pathol 26:1270-8. 2013
    ..Vascular involvement by endometriosis was identified in one case. Endometrial hyperplasia (n=2) and cancer (n=1) were also seen in the ectopic tissue. All patients were alive at follow-up (3-216 months, mean 67 months)...
  17. pmc High expression of survivin is prognostic of shorter survival but not predictive of adjuvant gemcitabine benefit in patients with resected pancreatic adenocarcinoma
    Hao Xie
    Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA
    J Histochem Cytochem 61:148-55. 2013
    ..However, survivin has no predictive value of adjuvant gemcitabine benefit...
  18. doi request reprint Histomorphologic and molecular features of pouch and peripouch adenocarcinoma: a comparison with ulcerative colitis-associated adenocarcinoma
    Wei Jiang
    Departments of Anatomic Pathology, Cleveland, OH 44195, USA
    Am J Surg Pathol 36:1385-94. 2012
    ....
  19. ncbi request reprint Correlation between endoscopic forceps biopsies and endoscopic mucosal resection with endoscopic ultrasound in patients with Barrett's esophagus with high-grade dysplasia and early cancer
    Prashanthi N Thota
    Department of Gastroenterology and Hepatology, Center of Excellence for Barrett s Esophagus, Cleveland Clinic, Cleveland, OH, 44195, USA
    Surg Endosc . 2016
    ..Our aims were to evaluate: (1) if endoscopic forceps biopsies correlated with EMR histology in these patients; (2) the utility of EUS compared to EMR; and (3) if accuracy of EUS varied based on grade of differentiation of tumor...
  20. doi request reprint Risk for esophageal neoplasia in Barrett's esophagus patients with mucosal changes indefinite for dysplasia
    Bėla Horváth
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio, USA
    J Gastroenterol Hepatol 30:262-7. 2015
    ..Our aim was to characterize the neoplastic risk of IND in BE patients and to identify predictors of neoplastic risk...
  21. pmc Evolution in the diagnosis and treatment of autoimmune pancreatitis: experience from a single tertiary care center
    Alper Yurci
    Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Int J Clin Exp Pathol 6:1317-26. 2013
    ..The aim of this study was to determine how the recognition and management of AIP has evolved at our center since the publication of the HISORt criteria in 2006...
  22. pmc Ribonucleotide reductase M2 does not predict survival in patients with resectable pancreatic adenocarcinoma
    Hao Xie
    Anatomic Pathology, Cleveland Clinic, Cleveland, OH 44195, USA
    Int J Clin Exp Pathol 5:347-55. 2012
    ..This study aimed to determine if RRM2 protein expression was prognostic in patients with resectable pancreatic adenocarcinoma and predictive of adjuvant gemcitabine benefit...
  23. pmc Microscopic colitis: is it a spectrum of inflammatory bowel disease?
    Ramprasad Jegadeesan
    Department of Gastroenterology and Hepatology, Digestive Disease Institute, Desk A30, Cleveland Clinic, Cleveland, OH 44195, United States
    World J Gastroenterol 19:4252-6. 2013
    ..Till then it might be prudent to follow up these patients to assess for the relapse of inflammatory bowel disease as well as for dysplasia surveillance. ..
  24. doi request reprint Paneth cells in colonic adenomas: association with male sex and adenoma burden
    Rish K Pai
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH 44195, USA
    Am J Surg Pathol 37:98-103. 2013
    ..Thus, the presence of a Paneth cell-containing adenoma may be a marker for increased risk of developing colorectal neoplasia...
  25. doi request reprint Distinct clinicohistologic features of inflammatory bowel disease-associated colorectal adenocarcinoma: in comparison with sporadic microsatellite-stable and Lynch syndrome-related colorectal adenocarcinoma
    Xiuli Liu
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Am J Surg Pathol 36:1228-33. 2012
    ....
  26. ncbi request reprint Protein kinase C-alpha inhibits the repair of oxidative phosphorylation after S-(1,2-dichlorovinyl)-L-cysteine injury in renal cells
    Xiuli Liu
    Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Am J Physiol Renal Physiol 287:F64-73. 2004
    ..This is the first report showing that PKC-alpha phosphorylates the catalytic subunit of F(1)F(0)-ATPase and that PKC-alpha plays an important role in regulating repair of mitochondrial function...
  27. pmc Expression of p53 predicts risk of prevalent and incident advanced neoplasia in patients with Barrett's esophagus and epithelial changes indefinite for dysplasia
    Bėla Horváth
    Department of Anatomic Pathology, The Cleveland Clinic, Cleveland, OH, USA
    Gastroenterol Rep (Oxf) 4:304-309. 2016
    ..We therefore performed a retrospective study to determine whether expression of these biomarkers was associated with the development of neoplasia in BE-IND patients...
  28. pmc Syndromic and sporadic inflammatory/hyperplastic small-bowel polyps: a comparative study
    Xiuli Liu
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Gastroenterol Rep (Oxf) 3:222-7. 2015
    ....
  29. doi request reprint The Significance of Sessile Serrated Polyps in Inflammatory Bowel Disease
    Whitney E Jackson
    Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio Section of Gastroenterology, Department of Veterans Affairs, Louis Stokes Cleveland Medical Center, Cleveland, Ohio Department of Pathology and Laboratory Medicine, North Shore Long Island Jewish Health System, New Hyde Park, New York Robert J Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, Arizona and Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio
    Inflamm Bowel Dis 22:2213-20. 2016
    ..We aim to characterize synchronous and metachronous lesions in IBD patients with an index serrated polyp and compare them to sporadic subjects with SSP...
  30. doi request reprint Risk stratification of patients with barrett's esophagus and low-grade dysplasia or indefinite for dysplasia
    Prashanthi N Thota
    Center of Excellence for Barrett s Esophagus, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio Electronic address
    Clin Gastroenterol Hepatol 13:459-465.e1. 2015
    ..Patients at higher risk for progression could benefit from intervention. We assessed rates of progression of LGD and indefinite for dysplasia (IND) and risk factors for progression to high-grade dysplasia (HGD) and EAC...
  31. doi request reprint Vascular endothelial growth factor levels in bile distinguishes pancreatic cancer from other etiologies of biliary stricture: a pilot study
    Udayakumar Navaneethan
    Section for Advanced Endoscopy and Pancreatobiliary Disorders, Department of Gastroenterology and Hepatology, Digestive Disease Institute, Desk A30, The Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA
    Dig Dis Sci 58:2986-92. 2013
    ..Determining the benign or malignant nature of biliary strictures can be challenging. Vascular endothelial growth factor (VEGF) plays an important role in tumor angiogenesis...
  32. ncbi request reprint Antiviral Treatment for Colonic Cytomegalovirus Infection in Ulcerative Colitis Patients Significantly Improved Their Surgery Free Survival
    YingHong Wang
    Victor W Fazio, MD Center for Inflammatory Bowel Disease Colorectal Department, Digestive Disease Institute, The Cleveland Clinic Foundation Department of Pathology, Cleveland Clinic, Cleveland, OH School of Medicine, St Georges University, Grenada, West Indies Department of Gastroenterology, Dalian Medical University, Dalian, P R China
    J Clin Gastroenterol . 2016
    ..0%. Infected patients are more likely to become hospitalized, have longer lengths of stay, and higher mortality rates. Current data are limited to small scale studies and showed conflicting result regarding the role of antiviral therapy...
  33. doi request reprint Mesenteric Arteriovenous Dysplasia/Vasculopathy Is Distinct From Fibromuscular Dysplasia
    Deepa T Patil
    Departments of Anatomic Pathology Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH Department of Anatomic Pathology, University of Utah, Salt Lake City, UT
    Am J Surg Pathol 40:1316-25. 2016
    ..Unlike FMD, surgical resection appears to be curative, with a favorable clinical outcome. Awareness of this vascular entity is important as patients may be potentially misdiagnosed as having CD and ischemic bowel disease. ..
  34. pmc Re-examination of sinusoidal deposition of complement 4d in liver allografts: experience from a single institution
    Mohannad Dugum
    Department of Internal Medicine, Medicine Institute, Cleveland Clinic Cleveland, OH, USA
    Int J Clin Exp Pathol 7:784-91. 2014
    ..This suggests that mechanisms other than allo-immunity activate complement. The mechanisms and clinical significance of C4d deposition in liver allografts in patients with PSC remain to be determined. ..
  35. pmc Poorly differentiated neuroendocrine carcinomas of the pancreas: a clinicopathologic analysis of 44 cases
    Olca Basturk
    Departments of Pathology Surgery Oncology, Memorial Sloan Kettering Cancer Center, New York, NY Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center Department of Surgery, Johns Hopkins University, Baltimore, MD Department of Pathology, Emory University, Atlanta, GA Department of Pathology, Penn State Hershey MC, Hershey Department of Pathology, University of Pittsburgh, Pittsburgh, PA Department of Pathology, Ohio State University, Columbus Department of Pathology, Cleveland Clinic, Cleveland, OH Department of Pathology, Mayo Clinic, Rochester, MN Department of Pathology, University of Michigan, Ann Arbor, MI Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA Department of Pathology, Indiana University, Indianapolis, IN Department of Pathology, Vanderbilt University, Nashville, TN Department of Pathology, Massachusetts General Hospital, Boston, MA Department of Pathology, Ospedale di Circolo, Varese, Italy Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, France
    Am J Surg Pathol 38:437-47. 2014
    ..In the pancreas, poorly differentiated neuroendocrine carcinomas include small cell carcinoma and large cell neuroendocrine carcinoma and are rare; data regarding their pathologic and clinical features are very limited...
  36. doi request reprint Lynch syndrome screening in newly diagnosed colorectal cancer in general pathology practice: from the revised Bethesda guidelines to a universal approach
    Jane Morrison
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Scand J Gastroenterol 46:1340-8. 2011
    ....
  37. pmc Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps
    Joanne Ngeow
    Genomic Medicine Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Gastroenterology 144:1402-9, 1409.e1-5. 2013
    ....
  38. doi request reprint Esophageal carcinoma cuniculatum: report of 9 cases
    Michael Landau
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Am J Surg Pathol 36:8-17. 2012
    ..Our report identifies a common histomorphologic pattern of esophageal carcinoma cuniculatum and supports the fact that surgical resection of the tumor by esophagectomy provides long-term survival even in patients with T3 tumor...
  39. doi request reprint Impact of De Novo and Preexisting Inflammatory Bowel Disease on the Outcome of Orthotopic Liver Transplantation
    Gursimran Kochhar
    Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio Departments of Internal Medicine, Quantitative Health Sciences, and Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, Ohio and Transplant Center, Cleveland Clinic Foundation, Cleveland, Ohio
    Inflamm Bowel Dis 22:1670-8. 2016
    ..The aims of our study were to evaluate the frequency of de novo IBD in patients with OLT and to assess the impact of de novo IBD and preexisting IBD on the outcome of OLT...
  40. doi request reprint Presence of Granulomas in Mesenteric Lymph Nodes Is Associated with Postoperative Recurrence in Crohn's Disease
    Yi Li
    Department of Colorectal Surgery, Department of Anatomic Pathology, and Center for Inflammatory Bowel Diseases, Cleveland Clinic Foundation, Cleveland, Ohio
    Inflamm Bowel Dis 21:2613-8. 2015
    ..Our aim was to assess the predictive value of the presence of granulomas in MLN as well as in bowel wall for postoperative recurrence of CD...
  41. ncbi request reprint Extramammary Paget disease in peristomal skin: report of a unique case
    Xiuli Liu
    Department of Anatomic Pathology, Cleveland Clinic, 9500 Euclid Avenue L25, Cleveland, OH 44195, USA
    J Gastrointest Surg 16:1967-71. 2012
    ..However, the occurrence of extramammary Paget disease has not been described in peristomal skin...
  42. doi request reprint Lymphocytic colitis and collagenous colitis: a review of clinicopathologic features and immunologic abnormalities
    Dipti Mahajan
    Department of Anatomic Pathology, Digestive Disease Institute, The Cleveland Clinic Foundation, OH, USA
    Adv Anat Pathol 19:28-38. 2012
    ..Advances in the understanding of the underlying immunologic abnormalities in the colonic tissue may help develop novel and effective therapies for these 2 diseases...
  43. doi request reprint A five-marker panel in a multiplex PCR accurately detects microsatellite instability-high colorectal tumors without control DNA
    Deepa T Patil
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH 44195, USA
    Diagn Mol Pathol 21:127-33. 2012
    ..Our study demonstrates that the 5-marker panel within a multiplex polymerase chain reaction of the Promega MSI analysis kit accurately identifies all MSI-H and 95.2% MSS colorectal tumors without using paired normal DNA...
  44. doi request reprint BRAF mutations in colorectal cancer are associated with distinct clinical characteristics and worse prognosis
    Matthew F Kalady
    Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Dis Colon Rectum 55:128-33. 2012
    ..Mutation in the BRAF oncogene is a key step in malignant transformation within the methylator pathway to colorectal cancer. However, there is a paucity of information about BRAF mutant colorectal tumors...
  45. ncbi request reprint Cytoprotective properties of novel nonpeptide calpain inhibitors in renal cells
    Xiuli Liu
    Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    J Pharmacol Exp Ther 302:88-94. 2002
    ....
  46. pmc Pouchitis Associated With Pelvic Radiation for Prostate Cancer
    Geeta Kulkarni
    Department of Gastroenterology Hepatology, Cleveland Clinic Foundation, Cleveland, OH
    ACG Case Rep J 3:e129. 2016
    ..We present a case of a 68-year-old male with pouchitis resulting from pelvic radiation for prostate cancer...
  47. doi request reprint Comparison of β-Catenin and LEF1 Immunohistochemical Stains in Desmoid-type Fibromatosis and its Selected Mimickers, With Unexpected Finding of LEF1 Positivity in Scars
    Youran Zou
    Departments of Department of Pathology Department of Colorectal Surgery, Cleveland Clinic, Cleveland, OH
    Appl Immunohistochem Mol Morphol . 2016
    ..In conclusion, this study demonstrated that LEF1 may be a useful marker in the differential diagnosis of DTF in certain contexts. However, caution should be exercised since LEF1 positivity can also be seen in scars...
  48. doi request reprint Clinical Implications of Noncaseating Granulomas on Histology in Patients with Ileal Pouches
    Ganglei Liu
    Department of Colorectal Surgery, The Cleveland Clinic, Cleveland, Ohio Department of Geriatric Surgery, The Second Xiangya Hospital, Central South University, Changsha, China and Departments of Gastroenterology Hepatology and Anatomic Pathology, The Cleveland Clinic, Cleveland, Ohio
    Inflamm Bowel Dis 21:1801-8. 2015
    ..The aim of this study was to evaluate clinical implications of noncaseating granuloma on histology in patients with ileal pouches...
  49. doi request reprint Signet-ring cell melanoma of the gastroesophageal junction: a case report and literature review
    Melissa A Grilliot
    Department of Anatomic Pathology, Cleveland Clinic, Ohio 44195, USA
    Arch Pathol Lab Med 136:324-8. 2012
    ..Therefore, it was determined this was likely a primary lesion. We review the literature and previously reported cases of this rare histologic variant of melanoma...
  50. pmc Macrophage migration inhibitory factor contributes to ethanol-induced liver injury by mediating cell injury, steatohepatitis, and steatosis
    Mark A Barnes
    Department of Molecular Medicine, Center for Liver Disease Research, Cleveland, OH, USA
    Hepatology 57:1980-91. 2013
    ..Chronic ethanol feeding also sensitized wildtype, but not MIF-/-, mice to lipopolysaccharide, increasing chemokine expression and monocyte recruitment into the liver...
  51. doi request reprint Reticulin staining clarifies florid benign signet ring cell change with mitotic activity in a penetrating gastric ulcer
    Julia Boncher
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA
    Am J Surg Pathol 35:762-6. 2011
    ..Reticulin staining of the involved glands is helpful for excluding the invasion of the lamina propria in signet ring cell change...
  52. doi request reprint Insulin-like growth factor I receptor β expression in hepatocellular carcinoma
    Xiuli Liu
    Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH 44195, USA
    Hum Pathol 42:882-91. 2011
    ..Targeted therapies against insulinlike growth factor receptors may be justifiable in the treatment of hepatocellular carcinoma...