Chwan Fwu Lin

Summary

Publications

  1. doi A new hydroxychavicol dimer from the roots of Piper betle
    Chwan Fwu Lin
    Department of Cosmetic Science, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan
    Molecules 18:2563-70. 2013
  2. doi Maximizing dermal targeting and minimizing transdermal penetration by magnolol/honokiol methoxylation
    Chwan Fwu Lin
    Department of Cosmetic Science, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan
    Int J Pharm 445:153-62. 2013
  3. pmc Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα
    Po Jen Chen
    Graduate Institute of Natural Products, School of Traditional Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
    Sci Rep 6:26554. 2016
  4. doi Casticin inhibits COX-2 and iNOS expression via suppression of NF-κB and MAPK signaling in lipopolysaccharide-stimulated mouse macrophages
    Chian Jiun Liou
    Department of Nursing, Chang Gung University of Science and Technology, 261 Wen Hwa 1st Road, Kwei Shan, Tao Yuan 333, Taiwan, ROC
    J Ethnopharmacol 158:310-6. 2014
  5. doi Anti-inflammatory activity and percutaneous absorption of quercetin and its polymethoxylated compound and glycosides: the relationships to chemical structures
    Chwan Fwu Lin
    Department of Cosmetic Science, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan
    Eur J Pharm Sci 47:857-64. 2012
  6. doi Antimicrobial activity of topically-applied soyaethyl morpholinium ethosulfate micelles against Staphylococcus species
    Shih Chun Yang
    Pharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, 259 Wen Hwa 1st Road, Kweishan, Taoyuan 333, Taiwan
    Nanomedicine (Lond) 11:657-71. 2016
  7. doi Sophoraflavanone G Induces Apoptosis in Human Leukemia Cells and Blocks MAPK Activation
    Zih Ying Li
    Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, Guishan District, Taoyuan City, Taiwan
    Am J Chin Med 44:165-76. 2016
  8. pmc Anti-inflammatory effects of Perilla frutescens in activated human neutrophils through two independent pathways: Src family kinases and Calcium
    Chun Yu Chen
    Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
    Sci Rep 5:18204. 2015
  9. doi Quantiosomes as a multimodal nanocarrier for integrating bioimaging and Carboplatin delivery
    Chwan Fwu Lin
    Department of Cosmetic Science, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan
    Pharm Res 31:2664-76. 2014
  10. doi Anti-inflammatory effect of sophoraflavanone G isolated from Sophora flavescens in lipopolysaccharide-stimulated mouse macrophages
    Zih Yi Wun
    Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, 261 Wen Hwa 1st Road, Kwei Shan, Tao Yuan 333, Taiwan, ROC
    Food Chem Toxicol 62:255-61. 2013

Collaborators

  • Jia You Fang
  • Yann Lii Leu
  • Chian Jiun Liou
  • Chun Yu Chen
  • Wen Chung Huang
  • Shih Chun Yang
  • Zih Ying Li
  • Po Jen Chen
  • Tsong Long Hwang
  • Yung Fong Tsai
  • Liang Mou Kuo
  • Shu Ju Wu
  • Zih Yi Wun
  • Ibrahim A Aljuffali
  • Yu Ling Wang
  • Jiann Jong Shen
  • Pei Yu Gu
  • Rong Syuan Tu
  • Calvin T Sung
  • Wei Che Sung
  • Yu Fang
  • Ming Chung Lee
  • Yu Ting Kuo
  • Pei Jen Chung
  • Hsuan Wu Yang
  • Wen Bin Len
  • Xin Ling Wu
  • Pei Yin Xu
  • Wei Tien Chang
  • Yu Ling Huang

Detail Information

Publications10

  1. doi A new hydroxychavicol dimer from the roots of Piper betle
    Chwan Fwu Lin
    Department of Cosmetic Science, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan
    Molecules 18:2563-70. 2013
    ..The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils...
  2. doi Maximizing dermal targeting and minimizing transdermal penetration by magnolol/honokiol methoxylation
    Chwan Fwu Lin
    Department of Cosmetic Science, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan
    Int J Pharm 445:153-62. 2013
    ..Daily administration of methoxylated permeants, especially dimethylhonokiol, produced no skin irritation for up to 7 days. Methoxylated magnolol and honokiol can be efficient and safe candidates for treating inflammatory skin disorders...
  3. pmc Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα
    Po Jen Chen
    Graduate Institute of Natural Products, School of Traditional Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
    Sci Rep 6:26554. 2016
    ....
  4. doi Casticin inhibits COX-2 and iNOS expression via suppression of NF-κB and MAPK signaling in lipopolysaccharide-stimulated mouse macrophages
    Chian Jiun Liou
    Department of Nursing, Chang Gung University of Science and Technology, 261 Wen Hwa 1st Road, Kwei Shan, Tao Yuan 333, Taiwan, ROC
    J Ethnopharmacol 158:310-6. 2014
    ..In this study, we evaluated the anti-inflammatory effects of casticin and its underlying molecular mechanism in lipopolysaccharide (LPS)-stimulated macrophages...
  5. doi Anti-inflammatory activity and percutaneous absorption of quercetin and its polymethoxylated compound and glycosides: the relationships to chemical structures
    Chwan Fwu Lin
    Department of Cosmetic Science, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan
    Eur J Pharm Sci 47:857-64. 2012
    ..Rutin provoked some skin redness and inflammation after a 5-day administration in nude mouse. QM caused no irritation, suggesting that it is a superior candidate for topical delivery...
  6. doi Antimicrobial activity of topically-applied soyaethyl morpholinium ethosulfate micelles against Staphylococcus species
    Shih Chun Yang
    Pharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, 259 Wen Hwa 1st Road, Kweishan, Taoyuan 333, Taiwan
    Nanomedicine (Lond) 11:657-71. 2016
    ..Here we evaluated the antibacterial efficacy of soyaethyl morpholinium ethosulfate (SME) micelles as an inherent bactericide against Staphylococcus aureus and methicillin-resistant S. aureus (MRSA)...
  7. doi Sophoraflavanone G Induces Apoptosis in Human Leukemia Cells and Blocks MAPK Activation
    Zih Ying Li
    Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, Guishan District, Taoyuan City, Taiwan
    Am J Chin Med 44:165-76. 2016
    ..These results suggest that SG might increase the effect of apoptosis on HL-60 cells through caspase-3 activation, mitochondrial-mediated pathways, and the MAPK pathway. ..
  8. pmc Anti-inflammatory effects of Perilla frutescens in activated human neutrophils through two independent pathways: Src family kinases and Calcium
    Chun Yu Chen
    Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
    Sci Rep 5:18204. 2015
    ..The anti-inflammatory effects of PFE on activated human neutrophils were mediated through two independent signaling pathways involving SFKs (Src and Lyn) and mobilization of intracellular Ca(2+). ..
  9. doi Quantiosomes as a multimodal nanocarrier for integrating bioimaging and Carboplatin delivery
    Chwan Fwu Lin
    Department of Cosmetic Science, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan
    Pharm Res 31:2664-76. 2014
    ..Here we report the development of quantiosomes, niosomes formed from Span 60, cholesterol, and quantum dots (QDs), for achieving sensitive bioimaging and anticancer drug delivery...
  10. doi Anti-inflammatory effect of sophoraflavanone G isolated from Sophora flavescens in lipopolysaccharide-stimulated mouse macrophages
    Zih Yi Wun
    Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, 261 Wen Hwa 1st Road, Kwei Shan, Tao Yuan 333, Taiwan, ROC
    Food Chem Toxicol 62:255-61. 2013
    ..These results suggest that SG has an anti-inflammatory effect, inhibiting pro-inflammatory cytokines and mediators production via interruption of the NF-κB and MAPK signaling pathways...