Yangxin Li

Summary

Publications

  1. ncbi request reprint Insulin-like growth factor 1 enhances the migratory capacity of mesenchymal stem cells
    Yangxin Li
    Laboratory of Heart Failure and Stem Cell, Texas Heart Institute, Houston, TX 77030, USA
    Biochem Biophys Res Commun 356:780-4. 2007
  2. doi request reprint The potential application and challenge of powerful CRISPR/Cas9 system in cardiovascular research
    Yangxin Li
    Institute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215123, PR China Electronic address
    Int J Cardiol . 2016
  3. doi request reprint A potential role for insulin-like growth factor signaling in induction of pluripotent stem cell formation
    Yangxin Li
    Texas Heart Institute, Houston, TX 77030, USA
    Growth Horm IGF Res 20:391-8. 2010
  4. doi request reprint Clusterin induces CXCR4 expression and migration of cardiac progenitor cells
    Yangxin Li
    Texas Heart Institute at St Luke s Episcopal Hospital, Houston, TX 77030, USA
    Exp Cell Res 316:3435-42. 2010
  5. doi request reprint Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis
    Yangxin Li
    Texas Heart Institute and The University of Texas Medical School, Houston, TX 77030, USA
    Biochem Biophys Res Commun 384:259-64. 2009
  6. pmc MicroRNA-221 regulates high glucose-induced endothelial dysfunction
    Yangxin Li
    Texas Heart Institute and The University of Texas Medical School, Heart Failure and Stem Cell, P O Box 20345, MC 2 255, 6770 Bertner Avenue, Houston, TX 77030, USA
    Biochem Biophys Res Commun 381:81-3. 2009
  7. doi request reprint IGF-1 prevents oxidative stress induced-apoptosis in induced pluripotent stem cells which is mediated by microRNA-1
    Yangxin Li
    The Texas Heart Institute and Center for Cardiovascular and Atherosclerosis Research, Department of Internal Medicine, University of Texas Medical School at Houston, TX 77030, USA
    Biochem Biophys Res Commun 426:615-9. 2012
  8. pmc MicroRNA-133a regulates insulin-like growth factor-1 receptor expression and vascular smooth muscle cell proliferation in murine atherosclerosis
    Song Gao
    The Texas Heart Institute at St Luke s Hospital, Houston, TX, USA The University of Texas Medical School at Houston, Houston, TX, USA
    Atherosclerosis 232:171-9. 2014
  9. pmc Apolipoprotein-J prevention of fetal cardiac myoblast apoptosis induced by ethanol
    Yangxin Li
    Texas Heart Institute and The University of Texas Health Science Center, Houston, TX 77030, USA
    Biochem Biophys Res Commun 357:157-61. 2007
  10. doi request reprint Inhibition of Gata4 and Tbx5 by Nicotine-Mediated DNA Methylation in Myocardial Differentiation
    Xue Yan Jiang
    Guangdong Cardiovascular Institute of Guangdong General Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, P R China The Center for Cardiovascular Biology and Atherosclerosis Research, University of Texas McGovern School of Medicine, and Texas Heart Institute, Houston, TX 77030, USA
    Stem Cell Reports . 2017

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Insulin-like growth factor 1 enhances the migratory capacity of mesenchymal stem cells
    Yangxin Li
    Laboratory of Heart Failure and Stem Cell, Texas Heart Institute, Houston, TX 77030, USA
    Biochem Biophys Res Commun 356:780-4. 2007
    ..These findings provide a new paradigm for biological effects of IGF-1 on MSC and have implications for the development of novel stem cell therapeutic strategies...
  2. doi request reprint The potential application and challenge of powerful CRISPR/Cas9 system in cardiovascular research
    Yangxin Li
    Institute for Cardiovascular Science and Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215123, PR China Electronic address
    Int J Cardiol . 2016
    ..In this review, we wish to highlight some key points regarding the future prospect of using CRISPR/Cas9 as a powerful tool for cardiovascular research, and as a novel therapeutic strategy to treat cardiovascular diseases...
  3. doi request reprint A potential role for insulin-like growth factor signaling in induction of pluripotent stem cell formation
    Yangxin Li
    Texas Heart Institute, Houston, TX 77030, USA
    Growth Horm IGF Res 20:391-8. 2010
    ....
  4. doi request reprint Clusterin induces CXCR4 expression and migration of cardiac progenitor cells
    Yangxin Li
    Texas Heart Institute at St Luke s Episcopal Hospital, Houston, TX 77030, USA
    Exp Cell Res 316:3435-42. 2010
    ..Thus, CST expression may increase CPCs migration via increasing CXCR4 expression and SDF-1/chemokine receptor signaling in a PI3/Akt-dependent manner...
  5. doi request reprint Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis
    Yangxin Li
    Texas Heart Institute and The University of Texas Medical School, Houston, TX 77030, USA
    Biochem Biophys Res Commun 384:259-64. 2009
    ..These results may have therapeutic implications in preventing/reducing diabetes associated endothelial dysfunction...
  6. pmc MicroRNA-221 regulates high glucose-induced endothelial dysfunction
    Yangxin Li
    Texas Heart Institute and The University of Texas Medical School, Heart Failure and Stem Cell, P O Box 20345, MC 2 255, 6770 Bertner Avenue, Houston, TX 77030, USA
    Biochem Biophys Res Commun 381:81-3. 2009
    ..These findings suggest that manipulation of the miR-221-c-kit pathway may offer a novel strategy for treatment of vascular dysfunction in diabetic patients...
  7. doi request reprint IGF-1 prevents oxidative stress induced-apoptosis in induced pluripotent stem cells which is mediated by microRNA-1
    Yangxin Li
    The Texas Heart Institute and Center for Cardiovascular and Atherosclerosis Research, Department of Internal Medicine, University of Texas Medical School at Houston, TX 77030, USA
    Biochem Biophys Res Commun 426:615-9. 2012
    ..In conclusion, IGF-1 inhibits H(2)O(2)-induced mitochondrial dysfunction, cytochrome-c release and apoptosis. IGF-1's effect is, at least partially, regulated by miR-1 in iPS cells...
  8. pmc MicroRNA-133a regulates insulin-like growth factor-1 receptor expression and vascular smooth muscle cell proliferation in murine atherosclerosis
    Song Gao
    The Texas Heart Institute at St Luke s Hospital, Houston, TX, USA The University of Texas Medical School at Houston, Houston, TX, USA
    Atherosclerosis 232:171-9. 2014
    ..This study tested whether miR-133a affects expression of IGF-1 receptor (IGF-1R) and proliferation of IGF-1-stimulated vascular smooth muscle cells (VSMC) in a murine model of atherosclerosis...
  9. pmc Apolipoprotein-J prevention of fetal cardiac myoblast apoptosis induced by ethanol
    Yangxin Li
    Texas Heart Institute and The University of Texas Health Science Center, Houston, TX 77030, USA
    Biochem Biophys Res Commun 357:157-61. 2007
    ..Thus, ApoJ serves as a cytoprotective protein that protects cardiac stem cells against EtOH cytotoxicity...
  10. doi request reprint Inhibition of Gata4 and Tbx5 by Nicotine-Mediated DNA Methylation in Myocardial Differentiation
    Xue Yan Jiang
    Guangdong Cardiovascular Institute of Guangdong General Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, P R China The Center for Cardiovascular Biology and Atherosclerosis Research, University of Texas McGovern School of Medicine, and Texas Heart Institute, Houston, TX 77030, USA
    Stem Cell Reports . 2017
    ..Our results present a direct repressive effect of nicotine on myocardial differentiation by regulating cardiac gene suppression via promoter DNA hypermethylation, contributing to the etiology of smoking-associated cardiac defects...
  11. doi request reprint Simvastatin-enhanced expression of promyogenic nuclear factors and cardiomyogenesis of murine embryonic stem cells
    Chenmin Yang
    The Center for Cardiovascular Biology and Atherosclerosis Research, The University of Texas Medical School at Houston, Houston, TX USA The Department of Obstetrics and Gynecology, Ruijin Hospital, Jiao Tong University Medical School, Shanghai, China Texas Heart Institute, Houston, TX, USA
    Vascul Pharmacol 60:8-16. 2014
    ..Thus, simvastatin treatment enhances ESC myogenesis during early development perhaps via a mechanism inhibiting the mevalonate-FPP/GGPP pathway. ..