Bruce A Lessey

Summary

Publications

  1. doi request reprint Eutopic endometrium in women with endometriosis: ground zero for the study of implantation defects
    Bruce A Lessey
    Greenville Hospital System, University of South Carolina School of Medicine, Greenville, Greenville, South Carolina, USA
    Semin Reprod Med 31:109-24. 2013
  2. pmc Endometrial beta3 integrin profile reflects endometrial receptivity defects in women with unexplained recurrent pregnancy loss
    Ariane Germeyer
    Department of Gynecological Endocrinology and Reproductive Medicine, University Hospital Heidelberg, Heidelberg, Germany
    Reprod Biol Endocrinol 12:53. 2014
  3. doi request reprint Clinical assessment and management of the endometrium in recurrent early pregnancy loss
    Bansari G Patel
    Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, South Carolina 29605, USA
    Semin Reprod Med 29:491-506. 2011
  4. pmc Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women
    Bruce A Lessey
    Division of Reproductive Endocrinology and Infertility, University Medical Group, Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, SC, USA
    Reprod Biol Endocrinol 4:S9. 2006
  5. doi request reprint Assessment of endometrial receptivity
    Bruce A Lessey
    Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University Medical Group, Greenville Hospital System, Greenville, SC 29605, USA
    Fertil Steril 96:522-9. 2011
  6. pmc Local and systemic factors and implantation: what is the evidence?
    Chelsea Fox
    Department of Obstetrics and Gynecology, Greenville Health System, Greenville, South Carolina
    Fertil Steril 105:873-84. 2016
  7. pmc Characterization of antiestrogenic activity of the Chinese herb, prunella vulgaris, using in vitro and in vivo (Mouse Xenograft) models
    Nancy H Collins
    Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, South Carolina 29605, USA
    Biol Reprod 80:375-83. 2009
  8. doi request reprint Luteal phase HCG support for unexplained recurrent pregnancy loss - a low hanging fruit?
    Chelsea Fox
    Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, SC 29605
    Reprod Biomed Online . 2016
  9. ncbi request reprint Two pathways of progesterone action in the human endometrium: implications for implantation and contraception
    Bruce A Lessey
    Division of Reproductive Endocrinology and Infertility, Center for Women s Medicine, Greenville Hospital System, 890 W Faris Road, Suite 470, Greenville, SC 29617, USA
    Steroids 68:809-15. 2003
  10. ncbi request reprint ECC-1 cells: a well-differentiated steroid-responsive endometrial cell line with characteristics of luminal epithelium
    Bilan Mo
    Center for Women s Medicine, Division of Reproductive Endocrinology and Infertility, Greenville Hospital System, Greenville, South Carolina 29605, USA
    Biol Reprod 75:387-94. 2006

Collaborators

Detail Information

Publications13

  1. doi request reprint Eutopic endometrium in women with endometriosis: ground zero for the study of implantation defects
    Bruce A Lessey
    Greenville Hospital System, University of South Carolina School of Medicine, Greenville, Greenville, South Carolina, USA
    Semin Reprod Med 31:109-24. 2013
    ..Understanding the pathophysiology of this disease will likely lead to better treatment options...
  2. pmc Endometrial beta3 integrin profile reflects endometrial receptivity defects in women with unexplained recurrent pregnancy loss
    Ariane Germeyer
    Department of Gynecological Endocrinology and Reproductive Medicine, University Hospital Heidelberg, Heidelberg, Germany
    Reprod Biol Endocrinol 12:53. 2014
    ..Herein we measure the expression of beta3 integrin subunit, a well-known implantation marker, in women with or without RPL and correlate it with the histological dating of the endometrial tissue...
  3. doi request reprint Clinical assessment and management of the endometrium in recurrent early pregnancy loss
    Bansari G Patel
    Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, South Carolina 29605, USA
    Semin Reprod Med 29:491-506. 2011
    ..The clinical assessment of the endometrium remains an important part of the investigation of couples with unexplained pregnancy loss...
  4. pmc Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women
    Bruce A Lessey
    Division of Reproductive Endocrinology and Infertility, University Medical Group, Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, SC, USA
    Reprod Biol Endocrinol 4:S9. 2006
    ..Such changes might be effectively treated by timely administration of the appropriate anti-estrogens to artificially block ER alpha and restore normal patterns of gene expression. Such treatments will require further clinical studies...
  5. doi request reprint Assessment of endometrial receptivity
    Bruce A Lessey
    Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University Medical Group, Greenville Hospital System, Greenville, SC 29605, USA
    Fertil Steril 96:522-9. 2011
    ..To provide a focused review of the scientific literature pertaining to endometrial receptivity...
  6. pmc Local and systemic factors and implantation: what is the evidence?
    Chelsea Fox
    Department of Obstetrics and Gynecology, Greenville Health System, Greenville, South Carolina
    Fertil Steril 105:873-84. 2016
    ..This review will address the current literature on endometrial and systemic factors related to impaired implantation and highlight recent advances in this area of reproductive medicine. ..
  7. pmc Characterization of antiestrogenic activity of the Chinese herb, prunella vulgaris, using in vitro and in vivo (Mouse Xenograft) models
    Nancy H Collins
    Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, South Carolina 29605, USA
    Biol Reprod 80:375-83. 2009
    ..Full characterization of this herb will likely provide new insights into the crosstalk between AHR and ESR1, with potential for therapeutic applications in women...
  8. doi request reprint Luteal phase HCG support for unexplained recurrent pregnancy loss - a low hanging fruit?
    Chelsea Fox
    Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, SC 29605
    Reprod Biomed Online . 2016
    ..5%; 95% CI 3.6-19.5; NNT = 9(5-27). These data suggest restoration of synchrony and CL support improves outcomes in women with RPL. Further randomized controlled trials of luteal-phase HCG in women with RPL appears warranted...
  9. ncbi request reprint Two pathways of progesterone action in the human endometrium: implications for implantation and contraception
    Bruce A Lessey
    Division of Reproductive Endocrinology and Infertility, Center for Women s Medicine, Greenville Hospital System, 890 W Faris Road, Suite 470, Greenville, SC 29617, USA
    Steroids 68:809-15. 2003
    ....
  10. ncbi request reprint ECC-1 cells: a well-differentiated steroid-responsive endometrial cell line with characteristics of luminal epithelium
    Bilan Mo
    Center for Women s Medicine, Division of Reproductive Endocrinology and Infertility, Greenville Hospital System, Greenville, South Carolina 29605, USA
    Biol Reprod 75:387-94. 2006
    ..These characteristics appear to be stable and persistent over multiple cell passages, making this well-differentiated cell line an excellent choice to study endocrine and paracrine regulation of endometrial epithelium in vitro...
  11. pmc Endometrial receptivity defects during IVF cycles with and without letrozole
    Paul B Miller
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University Medical Group, Greenville Hospital System, 890 W Faris Rd, Ste 470, Greenville, SC 29605, USA
    Hum Reprod 27:881-8. 2012
    ..Our aim was to study ways to improve IVF success rates in women with suspected endometrial receptivity defects...
  12. doi request reprint Homeostasis imbalance in the endometrium of women with implantation defects: the role of estrogen and progesterone
    Bruce A Lessey
    Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Greenville Health System, Greenville, South Carolina
    Semin Reprod Med 32:365-75. 2014
    ....
  13. doi request reprint Endometriosis and infertility
    Kristin J Holoch
    Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, South Carolina 29605, USA
    Clin Obstet Gynecol 53:429-38. 2010
    ..Medical management of endometriosis-associated infertility has not been proven outside of in vitro fertilization...