- CD98hc (SLC3A2) is a key regulator of keratinocyte adhesionGilles Lemaitre
CEA iRCM SCSR LGRK, 2 rue G Crémieux, Evry, France
J Dermatol Sci 61:169-79. 2011..In a recent description of proteins associated to caveolae at the plasma membrane of human basal epidermal cells, we demonstrated that CD98hc is localized with β1 integrin...
- Expression profiling of genes and proteins in HaCaT keratinocytes: proliferating versus differentiated stateGilles Lemaitre
Service de Génomique Fonctionnelle, CEA, Departement de Radiobiologie et Radiopathologie, Evry, France
J Cell Biochem 93:1048-62. 2004..Furthermore, some of these transcripts or proteins were similarly regulated in human primary keratinocytes and in human epidermis. The present study opens new areas of investigation in the comprehension of keratinocyte differentiation...
- CD98, a novel marker of transient amplifying human keratinocytesGilles Lemaitre
Service de Génomique Fonctionnelle, CEA, Evry, France
Proteomics 5:3637-45. 2005..We then isolated CD98-positive keratinocytes from fresh skin biopsies. Using clonogenic assays, we demonstrate that CD98 may be considered as a marker of transient amplifying human keratinocytes...
- Fibroblast growth factor type 2 signaling is critical for DNA repair in human keratinocyte stem cellsGhida Harfouche
CEA, IRCM, Laboratory of Genomics and Radiobiology of Keratinopoiesis, Evry, France
Stem Cells 28:1639-48. 2010..We propose that, apart from its well-known role as a strong mitogen and prosurvival factor, FGF2 helps to maintain genomic integrity in stem cells by activating stress-induced DNA repair...