Marwan Ghosn

Summary

Country: Lebanon

Publications

  1. doi request reprint A phase II randomized study comparing navelbine and capecitabine (Navcap) followed either by Navcap or by weekly docetaxel in the first-line treatment of HER-2/neu negative metastatic breast cancer
    M Ghosn
    Hematology and Medical Oncology Department, Hotel Dieu de France University Hospital, Alfred Naccache BLVD, PO Box 166830 Beirut, Lebanon
    Med Oncol 28:S142-51. 2011
  2. doi request reprint Sequential FOLFOX-6 and gemcitabine for locally advanced and/or metastatic pancreatic cancer
    M Ghosn
    Department of Oncology Hematology, Hotel Dieu de France University Hospital, Achrafieh, Blvd Alfred Naccache, P O Box 166830, Beirut, Lebanon
    Med Oncol 29:2831-7. 2012
  3. pmc Triple-negative breast cancer in Lebanon: a case series
    Marwan Ghosn
    Saint Joseph University School of Medicine, Beirut, Lebanon
    Oncologist 16:1552-6. 2011
  4. ncbi request reprint Sequential vinorelbine-capecitabine followed by docetaxel in advanced breast cancer: long-term results of a pilot phase II trial
    Marwan Ghosn
    Department of Oncology, Hematology, Hotel Dieu de France University Hospital, Achrafieh, Blvd Alfred Naccache, P O Box 166830, Beirut, Lebanon
    Cancer Chemother Pharmacol 62:11-8. 2008
  5. doi request reprint Experience with palliative care in patients with advanced cancer at a tertiary care hospital in a developing country
    Marwan Ghosn
    Hotel Dieu de France University Hospital, Achrafieh, Beirut, Lebanon
    Support Care Cancer 19:573-5. 2011
  6. ncbi request reprint FOLFOX-6 combination as the first-line treatment of locally advanced and/or metastatic pancreatic cancer
    Marwan Ghosn
    Hotel Dieu de France University Hospital, Beirut, Lebanon
    Am J Clin Oncol 30:15-20. 2007
  7. ncbi request reprint Phase II trial of capecitabine and vinorelbine as first-line chemotherapy for metastatic breast cancer patients
    Marwan Ghosn
    Department of Oncology Hematology, Hotel Dieu de France University Hospital, Achrafieh, Blvd Alfred Naccache, P O Box 166830, Beirut, Lebanon, France
    Anticancer Res 26:2451-6. 2006
  8. ncbi request reprint Characteristics of Gastric Cancer in Lebanon: a Descriptive Study from a Single Institutional Experience
    Tarek Assi
    Department of Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    J Gastrointest Cancer . 2016
  9. ncbi request reprint The role of palliative care in the last month of life in elderly cancer patients
    Tarek Assi
    Department of Hematology Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    Support Care Cancer . 2016
  10. doi request reprint Treatment of cancer patients in their last month of life: aimless chemotherapy
    Tarek Assi
    Department of Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    Support Care Cancer 24:1603-8. 2016

Collaborators

  • Georges Chahine
  • Toni Ibrahim
  • Aline Khazzaka
  • Fadi Elkarak
  • Mohamed A Kharfan-Dabaja
  • Ayman Tawil
  • J Kattan
  • Fadi Farhart
  • N Haddad
  • jean elcheikh
  • Tarek Assi
  • Fadi El Karak
  • Elie El Rassy
  • Fadi Farhat
  • Hampig Raphael Kourie
  • Tania Moussa
  • Samer Tabchi
  • Gerard Abadjian
  • Antoine Abi Lutfallah
  • Ralph Chebib
  • Samah Naderi
  • Marc Rassy
  • Claude Ghorra
  • Zaher K Otrock
  • Ibrahim R Bou-Orm
  • Mario Jreige
  • Mohamad Haidar
  • Aline Khazaka
  • Lara Naamani
  • Roland Eid
  • Aline Tohme
  • Jamale Rizkallah
  • Hampig R Kourie
  • Joelle Antoun
  • Maya Ghor
  • Dania N Chelala
  • Salma Faddoul
  • Fadi Nasr
  • Sami Richa
  • Joseph Gharios
  • Colette Hanna
  • Clarisse Kattan
  • Hussein Nassereddine
  • Claude Sader-Ghorra
  • Fady Haddad
  • Nizar Bitar
  • Hassan Sidani
  • Ahmad Ibrahim
  • Jad Saab
  • Michel Saade
  • Anas Mugharbel
  • Walid Mokaddem
  • Walid Dayeh
  • Ghazi Zaatari
  • Rami A Mahfouz
  • Georges Aftimos
  • Christina Khater
  • Zarouhie Meguerian
  • Ali Bazarbachi
  • Fadi S Farhat
  • Joseph Makdessi
  • Hussein Sadek
  • Khaled Ibrahim
  • Mirna El Hajj
  • Charles Sfeir
  • Ziad Salem
  • Dany Abi Gerges
  • Saad Khairallah
  • Fady Nasr

Detail Information

Publications28

  1. doi request reprint A phase II randomized study comparing navelbine and capecitabine (Navcap) followed either by Navcap or by weekly docetaxel in the first-line treatment of HER-2/neu negative metastatic breast cancer
    M Ghosn
    Hematology and Medical Oncology Department, Hotel Dieu de France University Hospital, Alfred Naccache BLVD, PO Box 166830 Beirut, Lebanon
    Med Oncol 28:S142-51. 2011
    ..Adverse events were mild. Arm A: grade 3-4 neutropenia (10%), grade 3 anemia (5%). Arm B: grade 3 neutropenia (6%), grade 3 anemia (6.2%), and grade 2 alopecia (12%)...
  2. doi request reprint Sequential FOLFOX-6 and gemcitabine for locally advanced and/or metastatic pancreatic cancer
    M Ghosn
    Department of Oncology Hematology, Hotel Dieu de France University Hospital, Achrafieh, Blvd Alfred Naccache, P O Box 166830, Beirut, Lebanon
    Med Oncol 29:2831-7. 2012
    ..In APC, FOLFOX-6 regimen followed by gemcitabine achieved an interesting RR within a tolerable level of toxicity. This regimen seems to warrant further investigation to confirm its efficacy...
  3. pmc Triple-negative breast cancer in Lebanon: a case series
    Marwan Ghosn
    Saint Joseph University School of Medicine, Beirut, Lebanon
    Oncologist 16:1552-6. 2011
    ..To determine the incidence, characteristics, and survival outcomes of triple-negative breast cancer patients in a medical oncology practice in Lebanon...
  4. ncbi request reprint Sequential vinorelbine-capecitabine followed by docetaxel in advanced breast cancer: long-term results of a pilot phase II trial
    Marwan Ghosn
    Department of Oncology, Hematology, Hotel Dieu de France University Hospital, Achrafieh, Blvd Alfred Naccache, P O Box 166830, Beirut, Lebanon
    Cancer Chemother Pharmacol 62:11-8. 2008
    ..To evaluate the response rate of the combination of capecitabine (C) and vinorelbine (V) followed by Docetaxel (D) in the 1st line treatment of advanced and metastatic breast cancer patients...
  5. doi request reprint Experience with palliative care in patients with advanced cancer at a tertiary care hospital in a developing country
    Marwan Ghosn
    Hotel Dieu de France University Hospital, Achrafieh, Beirut, Lebanon
    Support Care Cancer 19:573-5. 2011
    ..Revisiting the continuum of cancer care is called for to better identify the optimal timing of intervention and avoid end of life distress...
  6. ncbi request reprint FOLFOX-6 combination as the first-line treatment of locally advanced and/or metastatic pancreatic cancer
    Marwan Ghosn
    Hotel Dieu de France University Hospital, Beirut, Lebanon
    Am J Clin Oncol 30:15-20. 2007
    ..This phase II trial was conducted to investigate the efficacy of oxaliplatin, 5-FU, and folinic acid (FOLFOX-6) in previously untreated APC patients...
  7. ncbi request reprint Phase II trial of capecitabine and vinorelbine as first-line chemotherapy for metastatic breast cancer patients
    Marwan Ghosn
    Department of Oncology Hematology, Hotel Dieu de France University Hospital, Achrafieh, Blvd Alfred Naccache, P O Box 166830, Beirut, Lebanon, France
    Anticancer Res 26:2451-6. 2006
    ..The aim of this multicenter phase II trial was to assess the combination of capecitabine and vinorelbine as first-line chemotherapy in patients with metastatic breast cancer (MBC)...
  8. ncbi request reprint Characteristics of Gastric Cancer in Lebanon: a Descriptive Study from a Single Institutional Experience
    Tarek Assi
    Department of Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    J Gastrointest Cancer . 2016
    ..The epidemiology of gastric cancer in the Middle East has never been described. Therefore, the characteristics of gastric cancer in the Lebanese population will be reported in this study...
  9. ncbi request reprint The role of palliative care in the last month of life in elderly cancer patients
    Tarek Assi
    Department of Hematology Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    Support Care Cancer . 2016
    ..The purpose of our study is to evaluate the administration of chemotherapy in the last month of life (CLML) and to evaluate the impact of the palliative care consult (PCC) in the elderly patients...
  10. doi request reprint Treatment of cancer patients in their last month of life: aimless chemotherapy
    Tarek Assi
    Department of Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    Support Care Cancer 24:1603-8. 2016
    ..To our knowledge, this is the first study describing CLML of Middle Eastern patients with advanced cancer...
  11. ncbi request reprint Mesotheliomas in Lebanon: Witnessing a Change in Epidemiology
    Joseph Kattan
    Department of Hematology Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon E mail
    Asian Pac J Cancer Prev 17:4169-73. 2016
    ....
  12. doi request reprint Validation of the EORTC QLQ-INFO 25 questionnaire in Lebanese cancer patients: Is ignorance a Bliss?
    Samer Tabchi
    Faculty of Medicine, Hematology Oncology Department, Hotel Dieu de France University Hospital, Saint Joseph University, Beirut, Lebanon
    Qual Life Res 25:1597-604. 2016
    ....
  13. pmc Where does chemotherapy stands in the treatment of ampullary carcinoma? A review of literature
    Marwan Ghosn
    Marwan Ghosn, Hampig Raphael Kourie, Elie El Rassy, Fady Ghassan Haddad, Colette Hanna, Fadi El Karak, Department of Oncology, Faculty of Medicine, Saint Joseph University, Beirut 1104 2020, Lebanon
    World J Gastrointest Oncol 8:745-750. 2016
    ..We also review the medical treatment of this tumor and conclude to the necessity of multi-institutional randomized controlled studies for AC exclusively...
  14. doi request reprint EGFR mutation status in Middle Eastern patients with non-squamous non-small cell lung carcinoma: A single institution experience
    Samah Naderi
    Pathology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    Cancer Epidemiol 39:1099-102. 2015
    ..The occurrence of this mutation varies in terms of race; it is around 10% in Caucasians and can reach 30% in Asians. Its prevalence in our Middle Eastern region is not well known...
  15. doi request reprint Phase II trial of weekly Docetaxel, Zoledronic acid, and Celecoxib for castration-resistant prostate cancer
    Joseph Kattan
    Department of Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    Invest New Drugs 34:474-80. 2016
    ..We do not believe that there is compelling evidence to include either Celecoxib or Zoledronic acid in further phase II/III trials. ..
  16. pmc PET/CT Scanner and Bone Marrow Biopsy in Detection of Bone Marrow Involvement in Diffuse Large B-Cell Lymphoma
    Fadi El Karak
    School of Medicine, Saint Joseph University USJ, Beirut, Lebanon
    PLoS ONE 12:e0170299. 2017
    ..12; p = 0.03) while the BMB had not. PET shows superior performance to the BMB for the detection of marrow involvement in DLBCL. It may be considered as the first line examination of bone marrow instead of the biopsy...
  17. pmc Dilemma of first line regimens in metastatic pancreatic adenocarcinoma
    Marwan Ghosn
    Marwan Ghosn, Tony Ibrahim, Tarek Assi, Elie El Rassy, Hampig Raphael Kourie, Joseph Kattan, Department of Oncology, Faculty of Medicine, Saint Joseph University, Beirut 166830, Lebanon
    World J Gastroenterol 22:10124-10130. 2016
    ..Finally, we present studies revealing real life experiences and review the advantages and disadvantages of possible second-line therapies including their cost effectiveness...
  18. pmc Optimum chemotherapy for the management of advanced biliary tract cancer
    Marwan Ghosn
    Marwan Ghosn, Hampig Raphael Kourie, Elie El Rassy, Ralph Chebib, Fadi El Karak, Colette Hanna, Dolly Nasr, Department of Oncology, Faculty of Medicine, Saint Joseph University, Beirut 2038 3054, Lebanon
    World J Gastroenterol 21:4121-5. 2015
    ..Many new molecules targeting proliferation and survival pathways, the immune response and angiogenesis are currently undergoing phase I and II trials for the treatment of advanced BTC with promising results...
  19. ncbi request reprint Watch and Wait in Lebanese Chronic Lymphocytic Leukemia Patients: How Relevant is it?
    Antoine Abi Lutfallah
    Hematology Oncology Department, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon E mail
    Asian Pac J Cancer Prev 17:215-7. 2016
    ..Many approaches are implemented in the management of CLL from a watch and wait (WandW) strategy to chemotherapeutic regimens. We here reviewed our clinical practice for the relevance of the W and W strategy in Lebanese CLL patients...
  20. pmc Anal cancer treatment: current status and future perspectives
    Marwan Ghosn
    Marwan Ghosn, Hampig Raphael Kourie, Pamela Abdayem, Joelle Antoun, Dolly Nasr, Hematology Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    World J Gastroenterol 21:2294-302. 2015
    ..Many novel strategies, such as targeted therapies, vaccination, immunotherapy and photodynamic therapy are in clinical trials for the treatment of AC, with promising results in some indications. ..
  21. ncbi request reprint Current strategies in the treatment of metastatic hormone-refractory prostate cancer
    Marwan Ghosn
    Hematology Oncology Department, Hotel Dieu de France University Hospital, Beirut, Lebanon
    Tunis Med 83:74. 2005
  22. pmc Is metastatic pancreatic cancer an untargetable malignancy?
    Hampig Raphael Kourie
    Hampig Raphael Kourie, Joseph Gharios, Fadi Elkarak, Joelle Antoun, Marwan Ghosn, Department of Oncology, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    World J Gastrointest Oncol 8:297-304. 2016
    ..We aim in this paper to present the major causes rendering MPC an untargetable malignancy and to focus on the new therapeutic modalities based on TT in MPC. ..
  23. ncbi request reprint Distribution of testicular tumors in Lebanon: a single institution overview
    Tarek Assi
    Hematology Oncology Department, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon E mail
    Asian Pac J Cancer Prev 16:3443-6. 2015
    ..The purpose of this study was to estimate the epidemiological characteristics and histological subtypes of testicular tumors in the Lebanese population according to the WHO classification of testicular and paratesticular tumors...
  24. ncbi request reprint Outcome of cancer patients admitted to the intensive care unit (ICU)
    Marwan Ghosn
    Department of Hematology Oncology, Hotel Dieu de France Hospital, Beirut, Lebanon
    J Med Liban 50:132-6. 2002
    ..The duration of stay in the ICU was the only factor affecting mortality. Age, disease type and MV did not influence the mortality rate in this population...
  25. doi request reprint Immune checkpoint inhibitors renal side effects and management
    Elie El Rassy
    Department of Oncology, Hotel Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Lebanon
    Immunotherapy 8:1417-1425. 2016
    ..We also advocate the need for a multidisciplinary approach in patients with immune-related toxic adverse events...
  26. pmc Gastrointestinal cancers in the era of theranostics: Updates and future perspectives
    Marwan Ghosn
    Marwan Ghosn, Hampig Raphael Kourie, Samer Tabchi, Hematology Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
    World J Gastroenterol 21:8473-7. 2015
    ....
  27. pmc Optimum chemotherapy in the management of metastatic pancreatic cancer
    Marwan Ghosn
    Marwan Ghosn, Hampig Raphael Kourie, Fadi El Karak, Colette Hanna, Joelle Antoun, Dolly Nasr, Department of Oncology, Faculty of Medicine, Saint Joseph University, Beirut 166830, Lebanon
    World J Gastroenterol 20:2352-7. 2014
    ....
  28. doi request reprint A collaborative nationwide lymphoma study in Lebanon: incidence of various subtypes and analysis of associations with viruses
    Zaher K Otrock
    Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon
    Pathol Oncol Res 19:715-22. 2013
    ..The distribution of lymphoma subtypes in Lebanon appears similar to that of Western countries. The high rate of EBV positivity in HL and T-cell lymphoma by EBER deserves further investigation...