Natalia Laufer

Summary

Publications

  1. doi request reprint No reduction of HCV viral load in HIV patients co-infected with HCV genotype 1 during a 30 days course of nitazoxanide monotherapy
    N Laufer
    Centro Nacional de Referencia para el SIDA, Universidad de Buenos Aires, Argentina
    Antiviral Res 92:497-9. 2011
  2. pmc Abacavir does not influence the rate of virological response in HIV-HCV-coinfected patients treated with pegylated interferon and weight-adjusted ribavirin
    Natalia Laufer
    Infectious Diseases Unit, Hospital Clinic, Barcelona, Spain
    Antivir Ther 13:953-7. 2008
  3. pmc HCV RNA decline in the first 24 h exhibits high negative predictive value of sustained virologic response in HIV/HCV genotype 1 co-infected patients treated with peginterferon and ribavirin
    N Laufer
    Centro Nacional de Referencia para el SIDA, Universidad de Buenos Aires, Paraguay 2155, Buenos Aires, Argentina
    Antiviral Res 90:92-7. 2011
  4. doi request reprint Longitudinal analysis of the 5'UTR, E2-PePHD and NS5A-PKRBD genomic regions of hepatitis C virus genotype 1a in association with the response to peginterferon and ribavirin therapy in HIV-coinfected patients
    Federico Bolcic
    Instituto de Investigaciones Biomédicas en Retrovirus y Sida, Facultad de Medicina, Universidad de Buenos Aires, Argentina
    Antiviral Res 95:72-81. 2012
  5. pmc Env-Specific IgA from Viremic HIV-Infected Subjects Compromises Antibody-Dependent Cellular Cytotoxicity
    María Julia Ruiz
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires CONICET, Buenos Aires, Argentina
    J Virol 90:670-81. 2016
  6. pmc Early skewed distribution of total and HIV-specific CD8+ T-cell memory phenotypes during primary HIV infection is related to reduced antiviral activity and faster disease progression
    Yanina Ghiglione
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires CONICET, Buenos Aires, Argentina
    PLoS ONE 9:e104235. 2014
  7. doi request reprint A clustering phenomenon among HCV-1a strains among patients coinfected with HIV from Buenos Aires, Argentina
    Federico Bolcic
    Microbiology Department, National Reference Center for AIDS Research, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina
    J Med Virol 84:570-81. 2012
  8. ncbi request reprint HCV genotype distribution among HIV co-infected individuals in Argentina: relationship with host and viral factors
    Jorge F Quarleri
    Centro Nacional de Referencia para el SIDA, Dto Microbiologia, Facultad de Medicina, Universidad de Buenos Aires, CONICET, Argentina
    Acta Gastroenterol Latinoam 37:76-83. 2007
  9. pmc Host genetic factors associated with symptomatic primary HIV infection and disease progression among Argentinean seroconverters
    Romina Soledad Coloccini
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires CONICET, Buenos Aires, Argentina
    PLoS ONE 9:e113146. 2014
  10. ncbi request reprint Low rate of emergence of nevirapine and lamivudine resistance after post-partum interruption of a triple-drug regimen
    Hector Perez
    Fernandes Hospital, Infectious Diseases Unit, Buenos Aires, Argentina
    Antivir Ther 13:135-9. 2008

Collaborators

  • Gabriela Turk
  • Daniel Pryluka
  • Carlos Zala
  • Carolina Torres
  • Pedro Cahn
  • Carina Cesar
  • Francesc Vidal
  • Leandro R Jones
  • Lucila Cassino
  • Josep Mallolas
  • Jorge F Quarleri
  • A Martinez
  • Josephine H Cox
  • Carlos Remondegui
  • Horacio Salomon
  • Omar Sued
  • Yanina Ghiglione
  • Federico Bolcic
  • María Julia Ruiz
  • Mariano Sede
  • Juliana Falivene
  • María Eugenia Socías
  • María Magdalena Gherardi
  • Rita Reynoso
  • Hector Perez
  • María Pía Holgado
  • Luis Giavedoni
  • Romina Soledad Coloccini
  • Dario Dilernia
  • Javier Oscar Jurado
  • M Eugenia Socías
  • Julieta M Manrique
  • Micaela Parra
  • Ana María Rodríguez
  • Luis D Giavedoni
  • Cynthia Maeto
  • María Inés Figueroa
  • María Ángeles Pando
  • Andrea Mangano
  • Andrea Rubio
  • Franco Moretti
  • Maria Ines Figueroa
  • Virginia Pasquinelli
  • Rosa María Musella
  • Maria Florencia Quiroga
  • Gustavo Javier Martínez
  • Juan Trinchero
  • Eduardo Abbate
  • Ivana Belén Alvarez
  • Juan Castelli
  • María Collins
  • Ana Gun
  • Alberto Leoni
  • Gustavo Echenique
  • Viviana Alonso
  • Liliana Amante
  • Ariel Braverman
  • Alejandro Krolewiecki
  • Carolina Acuipil
  • Inés Zapiola
  • I Figueroa
  • M Belén Bouzas
  • Claudia Galloso
  • Patricia Maldonado
  • Mercedes Cabrini
  • J Gonzalo Tomás
  • E Lazaro
  • Marcela Acosta
  • Horacio Mingrone
  • Daniel Cangelosi
  • Cecilia Cánepa
  • ANDREA DUARTE
  • Eliana Loiza
  • Norma Porteiro
  • Marcela Ortiz
  • Manuel Gomez Carrillo
  • Maria E Lázaro
  • Valeria Fink
  • Raúl Román
  • Palmira Garda
  • Ravi Kavasery
  • Mariana Ceriotto
  • Maria B Bouzas
  • María I Figueroa
  • Fabio Crudo
  • Javier Yave
  • Lorena Abusamra
  • Graciela Ben
  • Patricia Patterson
  • Osvaldo Cando

Detail Information

Publications19

  1. doi request reprint No reduction of HCV viral load in HIV patients co-infected with HCV genotype 1 during a 30 days course of nitazoxanide monotherapy
    N Laufer
    Centro Nacional de Referencia para el SIDA, Universidad de Buenos Aires, Argentina
    Antiviral Res 92:497-9. 2011
    ..This data suggests that despite the promising results reported for HCV genotype 4 mono-infected patients, NTZ exhibit poor activity as monotherapy in HIV/HCV co-infected patients with genotype 1...
  2. pmc Abacavir does not influence the rate of virological response in HIV-HCV-coinfected patients treated with pegylated interferon and weight-adjusted ribavirin
    Natalia Laufer
    Infectious Diseases Unit, Hospital Clinic, Barcelona, Spain
    Antivir Ther 13:953-7. 2008
    ..The aim of our study was to evaluate the effect of ABC on the response rate to HCV therapy...
  3. pmc HCV RNA decline in the first 24 h exhibits high negative predictive value of sustained virologic response in HIV/HCV genotype 1 co-infected patients treated with peginterferon and ribavirin
    N Laufer
    Centro Nacional de Referencia para el SIDA, Universidad de Buenos Aires, Paraguay 2155, Buenos Aires, Argentina
    Antiviral Res 90:92-7. 2011
    ..Viral kinetics has emerged as one of the best prognostic factors of treatment outcome...
  4. doi request reprint Longitudinal analysis of the 5'UTR, E2-PePHD and NS5A-PKRBD genomic regions of hepatitis C virus genotype 1a in association with the response to peginterferon and ribavirin therapy in HIV-coinfected patients
    Federico Bolcic
    Instituto de Investigaciones Biomédicas en Retrovirus y Sida, Facultad de Medicina, Universidad de Buenos Aires, Argentina
    Antiviral Res 95:72-81. 2012
    ..The proteins appear to block interferon (IFN)-induced RNA-dependent protein kinase (PKR) and the 5'UTR may influence the viral lymphotropism...
  5. pmc Env-Specific IgA from Viremic HIV-Infected Subjects Compromises Antibody-Dependent Cellular Cytotoxicity
    María Julia Ruiz
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires CONICET, Buenos Aires, Argentina
    J Virol 90:670-81. 2016
    ..Furthermore, it underscores the complexity of the ADCC phenomenon and will help in an understanding of its underlying mechanisms...
  6. pmc Early skewed distribution of total and HIV-specific CD8+ T-cell memory phenotypes during primary HIV infection is related to reduced antiviral activity and faster disease progression
    Yanina Ghiglione
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires CONICET, Buenos Aires, Argentina
    PLoS ONE 9:e104235. 2014
    ..This report presents evidence concerning the link among CD8+ T-cell function, phenotype and virus control, hence supporting the instauration of early interventions to prevent irreversible immune damage. ..
  7. doi request reprint A clustering phenomenon among HCV-1a strains among patients coinfected with HIV from Buenos Aires, Argentina
    Federico Bolcic
    Microbiology Department, National Reference Center for AIDS Research, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina
    J Med Virol 84:570-81. 2012
    ..In conclusion, these results suggest the presence of an HCV-1a monophyletic cluster with a potential HIV co-transmission by phylogenetic analyses...
  8. ncbi request reprint HCV genotype distribution among HIV co-infected individuals in Argentina: relationship with host and viral factors
    Jorge F Quarleri
    Centro Nacional de Referencia para el SIDA, Dto Microbiologia, Facultad de Medicina, Universidad de Buenos Aires, CONICET, Argentina
    Acta Gastroenterol Latinoam 37:76-83. 2007
    ..Considering the increasing rate of HCV genotypes with lower response rates to treatment among HIV co-infected patients, antiretroviral therapy success might be jeopardized by HCV coinfection...
  9. pmc Host genetic factors associated with symptomatic primary HIV infection and disease progression among Argentinean seroconverters
    Romina Soledad Coloccini
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires CONICET, Buenos Aires, Argentina
    PLoS ONE 9:e113146. 2014
    ..Our aim was to analyze the association of these genetic factors in the presence of clinical symptoms during Primary HIV Infection (PHI) and disease progression within the first year...
  10. ncbi request reprint Low rate of emergence of nevirapine and lamivudine resistance after post-partum interruption of a triple-drug regimen
    Hector Perez
    Fernandes Hospital, Infectious Diseases Unit, Buenos Aires, Argentina
    Antivir Ther 13:135-9. 2008
    ..The aim of this study was to evaluate the emergence of strains resistant to NVP and lamivudine (3TC) after discontinuation of antiretroviral therapy (ART) with 3TC/zidovudine (ZDV)/NVP...
  11. doi request reprint Telomerase activity in peripheral blood mononuclear cells from HIV and HIV-HCV coinfected patients
    Rita Reynoso
    Centro Nacional de Referencia para el SIDA, Dto Microbiologia, Facultad de Medicina, Universidad de Buenos Aires, Argentina
    Virus Res 147:284-7. 2010
    ..The lack of an appropriate induction of this enzymatic activity after stimulus could partly account for immunosuppressive conditions observed in such patients...
  12. pmc ICOS, SLAM and PD-1 expression and regulation on T lymphocytes reflect the immune dysregulation in patients with HIV-related illness with pulmonary tuberculosis
    Javier Oscar Jurado
    Department of Biological Chemistry, University of Buenos Aires, School of Sciences, Buenos Aires, Argentina
    J Int AIDS Soc 15:17428. 2012
    ....
  13. doi request reprint Evolution of hepatitis C virus in HIV coinfected patients under antiretroviral therapy
    Mariano Sede
    Consejo Nacional de Investigaciones Cientificas y Tecnicas, Av Rivadavia 1917, C1083ACA Buenos Aires, Argentina Instituto de Investigaciones Biomédicas en Retrovirus y Sida INBIRS, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155 Piso 11, C1121ABG Buenos Aires, Argentina
    Infect Genet Evol 43:186-96. 2016
    ..Future studies using larger number of patients are needed to corroborate these hypotheses. ..
  14. pmc Th17 and Th17/Treg ratio at early HIV infection associate with protective HIV-specific CD8(+) T-cell responses and disease progression
    Juliana Falivene
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires CONICET, Buenos Aires, Argentina
    Sci Rep 5:11511. 2015
    ..Taken together, our results suggested a potential link between Th17 and Th17/Treg ratio with key HIV-specific CD8(+) T-cell responses against the infection. ..
  15. pmc Early Gag immunodominance of the HIV-specific T-cell response during acute/early infection is associated with higher CD8+ T-cell antiviral activity and correlates with preservation of the CD4+ T-cell compartment
    Gabriela Turk
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires CONICET, Buenos Aires, Argentina
    J Virol 87:7445-62. 2013
    ....
  16. doi request reprint Hepatitis B precore/core promoter mutations in isolates from HBV-monoinfected and HBV-HIV coinfected patients: a 3-yr prospective study
    Lucila Cassino
    Centro Nacional de Referencia para el SIDA, Dto Microbiologia, Facultad de Medicina, Universidad de Buenos Aires, Argentina
    J Clin Virol 46:354-9. 2009
    ..The course of chronic HBV infection is modified by HIV-coexistence...
  17. pmc Acute retroviral syndrome and high baseline viral load are predictors of rapid HIV progression among untreated Argentinean seroconverters
    M Eugenia Socías
    Hospital J A Fernandez, Cerviño 3356, Buenos Aires, Argentina
    J Int AIDS Soc 14:40. 2011
    ..Diagnosis of primary HIV infection (PHI) has important clinical and public health implications. HAART initiation at this stage remains controversial...
  18. doi request reprint Inter and intra-host variability of hepatitis C virus genotype 1a hypervariable envelope coding domains followed for a 4-11 year of human immunodeficiency virus coinfection and highly active antiretroviral therapy
    Mariano Sede
    Instituto de Investigaciones Biomédicas en Retrovirus y SIDA INBIRS, Universidad de Buenos Aires, Argentina Consejo Nacional de Investigaciones Científicas y Técnicas CONICET, Argentina
    Virology 471:19-28. 2014
    ..HCV quasispecies underwent very rapid evolution in HAART-treated patients (~3.1 × 10(-2) sub/site/year) following the recovery of the host immunocompetence irrespectively of the virological response to HAART...
  19. pmc Magnitude, breadth, and functional profile of T-cell responses during human immunodeficiency virus primary infection with B and BF viral variants
    Gabriela Turk
    Centro Nacional de Referencia para el SIDA, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155 Piso 11, C1121ABG Buenos Aires, Argentina
    J Virol 82:2853-66. 2008
    ..Screening T-cell responses with multiple sets increased sensitivity. Further support for the notion of polyfunctional CD8(+) T-cell requirement to better control viral replication is also provided...