Ali A Dashti

Summary

Affiliation: Kuwait University
Country: Kuwait

Publications

  1. doi Thrombosis risk in carriers of the factor V Leiden mutation: is it associated with a defined skin color?
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, Kuwait
    Pathol Res Pract 207:671-3. 2011
  2. ncbi Linkage of ciprofloxacin resistance with a single genotypic cluster of Klebsiella pneumoniae
    A A Dashti
    Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Health Science Center, Kuwait University, Sulabikhat
    Int J Antimicrob Agents 27:73-6. 2006
  3. ncbi Retrospective study of an outbreak in a Kuwaiti hospital of multidrug-resistant Klebsiella pneumoniae possessing the new SHV-112 extended-spectrum beta-lactamase
    A A Dashti
    Department of Medical Laboratory Sciences, Health Science Center, Kuwait University, Kuwait
    J Chemother 22:335-8. 2010
  4. doi Race differences in the prevalence of the factor V Leiden mutation in Kuwaiti nationals
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, P O Box 31470, 90805, Sulaibekhat, Kuwait
    Mol Biol Rep 38:3623-8. 2011
  5. doi Factor V Leiden mutation in Arabs in Kuwait by real-time PCR: different values for different Arabs
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences Kuwait University, Sulaibekhat, Kuwait
    J Hum Genet 55:232-5. 2010
  6. doi Transmission of a Klebsiella pneumoniae clone harbouring genes for CTX-M-15-like and SHV-112 enzymes in a neonatal intensive care unit of a Kuwaiti hospital
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Science, Health Sciences Centre, Kuwait University, and Microbiology Laboratory, Al Jahra Hospital, Kuwait
    J Med Microbiol 59:687-92. 2010
  7. doi Can we rely on one laboratory test in detection of extended-spectrum beta-lactamases among Enterobacteriaceae? An evaluation of the Vitek 2 system and comparison with four other detection methods in Kuwait
    A A Dashti
    Department of Medical Laboratory Sciences, Health Science Centre, Kuwait University, PO Box 31470, Sulabikhat 90805, Kuwait
    J Clin Pathol 62:739-42. 2009
  8. ncbi Salmonella enterica Serotype typhi in Kuwait and its reduced susceptibility to ciprofloxacin
    A A Dashti
    Department of Medical Labortory Sciences, Health Science Center, Kuwait University, Suleibikhat, Kuwait
    J Chemother 20:297-302. 2008
  9. ncbi Extended-spectrum beta-lactamase-producing Escherichia coli isolated in the Al-Amiri Hospital in 2003 and compared with isolates from the Farwania hospital outbreak in 1994-96 in Kuwait
    A A Dashti
    Department of Medical Laboraoty, Faculty of Allied Health Sciences, Health Science Center, Kuwait University, Kuwait
    J Chemother 19:271-6. 2007
  10. ncbi Characterization of extended-spectrum beta-lactamase (ESBL)-producing Kuwait and UK strains identified by the Vitek system, and subsequent comparison of the Vitek system with other commercial ESBL-testing systems using these strains
    A A Dashti
    Medical Laboratory Sciences, Health Science Centre, Kuwait University, Kuwait
    J Med Microbiol 55:417-21. 2006

Collaborators

Detail Information

Publications16

  1. doi Thrombosis risk in carriers of the factor V Leiden mutation: is it associated with a defined skin color?
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, Kuwait
    Pathol Res Pract 207:671-3. 2011
    ..5%) of the total subjects: 8 (10.5%) skin type II, 7 (7.3%) skin type IV, and 2 (7.1%) skin type VI. Therefore, FVL shows an even distribution in Arabs, and all Arabs residing in Kuwait should be tested for FVL irrespective of skin color...
  2. ncbi Linkage of ciprofloxacin resistance with a single genotypic cluster of Klebsiella pneumoniae
    A A Dashti
    Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Health Science Center, Kuwait University, Sulabikhat
    Int J Antimicrob Agents 27:73-6. 2006
    ..pneumoniae. The sequencing results demonstrated that alteration of the GyrA subunit of DNA gyrase at amino acid 83 and/or amino acid 87 plays a central role in conferring high-level quinolone resistance in K. pneumoniae possessing ESBLs...
  3. ncbi Retrospective study of an outbreak in a Kuwaiti hospital of multidrug-resistant Klebsiella pneumoniae possessing the new SHV-112 extended-spectrum beta-lactamase
    A A Dashti
    Department of Medical Laboratory Sciences, Health Science Center, Kuwait University, Kuwait
    J Chemother 22:335-8. 2010
    ..pneumoniae in Kuwait and probably in other middle eastern countries, and researchers in the region should make use of molecular techniques to look for more novel mutations in ESBL-producing strains of K. pneumoniae...
  4. doi Race differences in the prevalence of the factor V Leiden mutation in Kuwaiti nationals
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, P O Box 31470, 90805, Sulaibekhat, Kuwait
    Mol Biol Rep 38:3623-8. 2011
    ..Therefore, testing and providing genetic consultation for FVL may be needed in those Kuwaitis only which should save time, cost and efforts. However, this assumption should be confirmed by other studies and on larger number of cases...
  5. doi Factor V Leiden mutation in Arabs in Kuwait by real-time PCR: different values for different Arabs
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences Kuwait University, Sulaibekhat, Kuwait
    J Hum Genet 55:232-5. 2010
    ..In conclusion, the prevalence of FVL in Arabs living in Kuwait is as high as in Caucasians. There is a difference in prevalence among Arabs themselves, being relatively lower in Kuwaitis than in non-Kuwaitis...
  6. doi Transmission of a Klebsiella pneumoniae clone harbouring genes for CTX-M-15-like and SHV-112 enzymes in a neonatal intensive care unit of a Kuwaiti hospital
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Science, Health Sciences Centre, Kuwait University, and Microbiology Laboratory, Al Jahra Hospital, Kuwait
    J Med Microbiol 59:687-92. 2010
    ..Further studies are recommended to determine whether this clone is also spreading in other Kuwaiti hospitals...
  7. doi Can we rely on one laboratory test in detection of extended-spectrum beta-lactamases among Enterobacteriaceae? An evaluation of the Vitek 2 system and comparison with four other detection methods in Kuwait
    A A Dashti
    Department of Medical Laboratory Sciences, Health Science Centre, Kuwait University, PO Box 31470, Sulabikhat 90805, Kuwait
    J Clin Pathol 62:739-42. 2009
    ..Kuwaiti hospitals use one laboratory test for detecting ESBL bacteria. This study evaluated whether that was sufficient to detect ESBL bacteria, and compared the Vitek system with other detection systems...
  8. ncbi Salmonella enterica Serotype typhi in Kuwait and its reduced susceptibility to ciprofloxacin
    A A Dashti
    Department of Medical Labortory Sciences, Health Science Center, Kuwait University, Suleibikhat, Kuwait
    J Chemother 20:297-302. 2008
    ..Reduced susceptibility to ciprofloxacin in MDR S. typhi has increased from (11%) in 1995-1996 to (67%) in 2002-2003 and from (0%) to (23%) in susceptible strains. Mutation of the gyrA gene is the mechanism most often responsible...
  9. ncbi Extended-spectrum beta-lactamase-producing Escherichia coli isolated in the Al-Amiri Hospital in 2003 and compared with isolates from the Farwania hospital outbreak in 1994-96 in Kuwait
    A A Dashti
    Department of Medical Laboraoty, Faculty of Allied Health Sciences, Health Science Center, Kuwait University, Kuwait
    J Chemother 19:271-6. 2007
    ..The epidemiology of ESBL E. coli in Kuwait is complex. Many distinct strains are already present in the population, as shown by the results of PFGE. Several testing methods may be required to detect all strains harboring ESBLs...
  10. ncbi Characterization of extended-spectrum beta-lactamase (ESBL)-producing Kuwait and UK strains identified by the Vitek system, and subsequent comparison of the Vitek system with other commercial ESBL-testing systems using these strains
    A A Dashti
    Medical Laboratory Sciences, Health Science Centre, Kuwait University, Kuwait
    J Med Microbiol 55:417-21. 2006
    ..coli strains, the Vitek susceptibility card with its integral ESBL test offers the clinical laboratory a valuable and quick option to screen for ESBL-producing Klebsiella spp. and E. coli as part of the routine laboratory methodology...
  11. pmc Ciprofloxacin-resistant Salmonella enterica serovar typhi from Kuwait with novel mutations in gyrA and parC genes
    Tzonyo Dimitrov
    Department of Microbiology, Faculty of Medicine, Kuwait University, P O Box 24923, Safat 13110, Kuwait
    J Clin Microbiol 47:208-11. 2009
    ..Both isolates had three novel gyrA mutations (55-Leu-->Trp, 87-Asp-->Ala, and 106-Gln-->Arg) and three novel parC mutations (84-Glu-->Lys, 106-Trp-->Gly, and 128-Tyr-->Asp)...
  12. ncbi High prevalence of activated protein C resistance and factor V Leiden mutation in an Arab population and patients with venous thrombosis in Kuwait
    Mehrez M Jadaon
    Department of Medical Laboratory Sciences, Kuwait University, Kuwait
    Diagn Mol Pathol 19:180-3. 2010
    ..Studies on Arab patients and populations were very inconsistent. This study reports APC-R and FVL in Arabs living in Kuwait...
  13. ncbi Factor V Kuwait: a novel mutation in the coagulation factor V gene discovered in Kuwait
    Mehrez M Jadaon
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, Kuwait
    Med Princ Pract 15:102-5. 2006
    ..It was the aim of this study to report a new point mutation in the clotting factor V gene in the general Arab population...
  14. doi Whole-blood polymerase chain reaction and restriction fragment length polymorphism: a simplified method by microwave irradiation
    Mehrez M Jadaon
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, Sulaibekhat 90805, Kuwait
    Med Princ Pract 18:280-3. 2009
    ....
  15. pmc The characterization and antibiotic resistance profiles of clinical Escherichia coli O25b-B2-ST131 isolates in Kuwait
    Ali A Dashti
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Kuwait University, Sulaibekhat, Sulaibekhat, 90805, Kuwait
    BMC Microbiol 14:214. 2014
    ..Our main objectives in this study were to characterise the multi-drug resistant (MDR) isolates of this lineage in Kuwait, and to demonstrate whether reduced susceptibility is spread clonally...
  16. ncbi Single nucleotide polymorphisms at erythropoietin, superoxide dismutase 1, splicing factor, arginine/serin-rich 15 and plasmacytoma variant translocation genes association with diabetic nephropathy
    Maisaa Alwohhaib
    Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Health Science Center, Kuwait
    Saudi J Kidney Dis Transpl 25:577-81. 2014
    ..75) compared with Group 2 (0.62). Susceptibility to diabetes-associated nephropathy is partially mediated by genetic predisposition, and screening tests may open the gate for new therapeutic approaches. ..