Kevin R Kozak

Summary

Publications

  1. pmc Giant cell glioblastoma: a glioblastoma subtype with distinct epidemiology and superior prognosis
    Kevin R Kozak
    University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, 600 Highland Ave, K4 362, Madison, WI 53792, USA
    Neuro Oncol 11:833-41. 2009
  2. pmc Antitumor activity of Triolimus: a novel multidrug-loaded micelle containing Paclitaxel, Rapamycin, and 17-AAG
    Jason R Hasenstein
    University of Wisconsin Madison, School of Medicine and Public Health, Department of Human Oncology, 1111 Highland Avenue, WIMR 3153, Madison, WI 53705, USA
    Mol Cancer Ther 11:2233-42. 2012
  3. pmc Bladder preservation for localized muscle-invasive bladder cancer: the survival impact of local utilization rates of definitive radiotherapy
    Kevin R Kozak
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 27408, USA
    Int J Radiat Oncol Biol Phys 83:e197-204. 2012
  4. pmc Refusal of radiation therapy and its associated impact on survival
    Maryam Hamidi
    Department of Human Oncology, University of Wisconsin, Madison, 53792, USA
    Am J Clin Oncol 33:629-32. 2010
  5. pmc Expression of angiopoietin-TIE system components in angiosarcoma
    Darya Buehler
    Department of Pathology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Mod Pathol 26:1032-40. 2013
  6. pmc Adult gliosarcoma: epidemiology, natural history, and factors associated with outcome
    Kevin R Kozak
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Neuro Oncol 11:183-91. 2009
  7. doi Triolimus: A Multi-Drug Loaded Polymeric Micelle Containing Paclitaxel, 17-AAG, and Rapamycin as a Novel Radiosensitizer
    Keishiro Tomoda
    Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, WI, 53705, USA
    Macromol Biosci . 2016
  8. pmc Primary cardiac sarcoma
    Maryam Hamidi
    Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53705, USA
    Ann Thorac Surg 90:176-81. 2010
  9. doi External beam radiotherapy for colon cancer: patterns of care
    Emily F Dunn
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 76:1420-4. 2010
  10. pmc Differential expression of 2',3'-cyclic-nucleotide 3'-phosphodiesterase and neural lineage markers correlate with glioblastoma xenograft infiltration and patient survival
    Michael Zorniak
    Neuroscience Training Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Clin Cancer Res 18:3628-36. 2012

Collaborators

Detail Information

Publications21

  1. pmc Giant cell glioblastoma: a glioblastoma subtype with distinct epidemiology and superior prognosis
    Kevin R Kozak
    University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, 600 Highland Ave, K4 362, Madison, WI 53792, USA
    Neuro Oncol 11:833-41. 2009
    ..The prognosis of GC is superior to that of GBM, and long-term survival is possible, suggesting aggressive therapy is warranted...
  2. pmc Antitumor activity of Triolimus: a novel multidrug-loaded micelle containing Paclitaxel, Rapamycin, and 17-AAG
    Jason R Hasenstein
    University of Wisconsin Madison, School of Medicine and Public Health, Department of Human Oncology, 1111 Highland Avenue, WIMR 3153, Madison, WI 53705, USA
    Mol Cancer Ther 11:2233-42. 2012
    ..These observations provide strong support for further development of Triolimus and an important proof of concept for safe, effective nanoparticle-based delivery of three complementary anticancer agents...
  3. pmc Bladder preservation for localized muscle-invasive bladder cancer: the survival impact of local utilization rates of definitive radiotherapy
    Kevin R Kozak
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 27408, USA
    Int J Radiat Oncol Biol Phys 83:e197-204. 2012
    ..This study examines the management and outcomes of muscle-invasive bladder cancer in the United States...
  4. pmc Refusal of radiation therapy and its associated impact on survival
    Maryam Hamidi
    Department of Human Oncology, University of Wisconsin, Madison, 53792, USA
    Am J Clin Oncol 33:629-32. 2010
    ..Data on factors associated with RT refusal are limited. Furthermore, the effect of RT refusal on outcome has not been clearly defined...
  5. pmc Expression of angiopoietin-TIE system components in angiosarcoma
    Darya Buehler
    Department of Pathology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Mod Pathol 26:1032-40. 2013
    ..We conclude that components of the ANGPT-TIE system are commonly expressed in angiosarcomas. Reduced expression of these proteins is associated with non-vasoformative and clinically more aggressive lesions...
  6. pmc Adult gliosarcoma: epidemiology, natural history, and factors associated with outcome
    Kevin R Kozak
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Neuro Oncol 11:183-91. 2009
    ..However, these retrospective findings suggest tumor excision, as opposed to biopsy only, and adjuvant RT may improve outcome. Despite therapy, prognosis remains dismal and outcomes may be inferior to those seen in GBM patients...
  7. doi Triolimus: A Multi-Drug Loaded Polymeric Micelle Containing Paclitaxel, 17-AAG, and Rapamycin as a Novel Radiosensitizer
    Keishiro Tomoda
    Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, WI, 53705, USA
    Macromol Biosci . 2016
    ..These results suggest that further investigations of Triolimus in combination with radiation therapy are merited...
  8. pmc Primary cardiac sarcoma
    Maryam Hamidi
    Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53705, USA
    Ann Thorac Surg 90:176-81. 2010
    ..The presentation, management, and outcome of patients with primary cardiac sarcomas are not well defined. Furthermore, the role of adjuvant therapy has not been delineated in the management of primary cardiac sarcomas...
  9. doi External beam radiotherapy for colon cancer: patterns of care
    Emily F Dunn
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 76:1420-4. 2010
    ..To address the paucity of data regarding RT use in colon cancer management, we examined the RT patterns of care in this patient population...
  10. pmc Differential expression of 2',3'-cyclic-nucleotide 3'-phosphodiesterase and neural lineage markers correlate with glioblastoma xenograft infiltration and patient survival
    Michael Zorniak
    Neuroscience Training Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Clin Cancer Res 18:3628-36. 2012
    ..We characterized glioblastoma stem-like cells (GSC) according to developmental neural lineage markers and correlated their expression with patient survival...
  11. ncbi Injectable (-)-gossypol-loaded Pluronic P85 micelles for cancer chemoradiotherapy
    Keishiro Tomoda
    a Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, Madison, USA
    Int J Radiat Biol . 2016
    ..In this study, the radiosensitizing effect of (-)-gossypol, more potent Bcl protein inhibitor, with Pluronic P85 was investigated...
  12. pmc Impact of a Contralateral Tumor Nodule on Survival in Non-Small-Cell Lung Cancer
    Zachary S Morris
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin St Luke s Mountain States Tumor Institute, Twin Falls, Idaho Division of Biostatistics and Bioinformatics, University of Maryland Greenebaum Cancer Center, Baltimore, Maryland Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland and Department of Radiation Oncology, Mercy Regional Cancer Center, Janesville, Wisconsin
    J Thorac Oncol 10:1608-15. 2015
    ..Here, we aim to determine whether NSCLC patients with M1a disease due only to a contralateral tumor nodule exhibit a favorable prognosis relative to other M1a or M1b patients...
  13. pmc The role of radiation in retroperitoneal sarcomas
    Pranshu Mohindra
    Department of Human Oncology, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, K4 B100, Madison, WI, 53792, USA
    Curr Treat Options Oncol 14:425-41. 2013
    ..Participation in prospective studies should be highly encouraged...
  14. pmc Acute hematologic and mucosal toxicities in head and neck cancer patients undergoing chemoradiotherapy: a comparison of 3D-CRT, IMRT, and helical tomotherapy
    Tim J Kruser
    Department of Human Oncology, University of Wisconsin Carbone Cancer Center K4 B100 CSC, 600 Highland Avenue, Madison, WI 53792
    Technol Cancer Res Treat 12:383-9. 2013
    ....
  15. pmc Elevation of prostaglandin E2 in lung cancer patients with digital clubbing
    Kevin R Kozak
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    J Thorac Oncol 7:1877-8. 2012
    ..These findings highlight a potential role for PGE2 in the pathogenesis of digital clubbing. Furthermore, this result identifies a lung cancer subpopulation that may uniquely benefit from cyclooxygenase inhibition...
  16. pmc Computational modelling of anti-angiogenic therapies based on multiparametric molecular imaging data
    Benjamin Titz
    Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Phys Med Biol 57:6079-101. 2012
    ..Our results suggest that, upon further validation, the application of image-driven computational models may afford opportunities to optimize dosing regimens and combination therapies in a patient-specific manner...
  17. doi Statin use in cancer patients with brain metastases: a missed communication opportunity at the end of life
    Jacqueline A Mullvain
    University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA
    Support Care Cancer 23:2643-8. 2015
    ..We propose reasons for the unnecessary continuation of preventive care and suggest that it is a frequently missed communication opportunity to discuss prognosis in a concrete manner...
  18. pmc Examination of Gossypol-Pluronic Micelles as Potential Radiosensitizers
    Keishiro Tomoda
    Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, Wisconsin, 53705, USA
    AAPS J 17:1369-75. 2015
    ..These results suggest that Pluronic micelles readily solubilize gossypol and that the combination of gossypol and P85 may augment the therapeutic effects of ionizing radiation. ..
  19. pmc Pharmacokinetic study of 3-in-1 poly(ethylene glycol)-block-poly(D, L-lactic acid) micelles carrying paclitaxel, 17-allylamino-17-demethoxygeldanamycin, and rapamycin
    Ho Chul Shin
    Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, WI 53705, USA
    J Control Release 163:93-9. 2012
    ....
  20. pmc Low rates of heterotopic ossification after resurfacing hip arthroplasty with use of prophylactic radiotherapy in select patients
    Tim J Kruser
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    J Arthroplasty 27:1349-53. 2012
    ..3%). Further study is needed to establish optimal selection criteria for HO prophylaxis after SRA...
  21. pmc Efficacy of Tie2 receptor antagonism in angiosarcoma
    Jason R Hasenstein
    Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, USA
    Neoplasia 14:131-40. 2012
    ..These data identify Tie2 antagonism as a potential novel, targeted therapy for angiosarcomas and provide a foundation for further investigation of Tie2 inhibition, alone and in combinations, in the management of this disease...