Tae Yong Kim

Summary

Affiliation: University of Ulsan
Country: Korea

Publications

  1. pmc Prognostic parameters for recurrence of papillary thyroid microcarcinoma
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    BMC Cancer 8:296. 2008
  2. ncbi request reprint The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 65:364-8. 2006
  3. doi request reprint Serum epidermal growth factor is associated with prognosis and hormone receptor status in patients with HER2-positive metastatic breast cancer treated with first-line trastuzumab plus taxane chemotherapy
    Ji Won Kim
    Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak Ro, Jongno gu, Seoul, 110 744, Korea
    Cancer Chemother Pharmacol 72:1023-9. 2013
  4. doi request reprint Change of serum antithyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin-negative patients with differentiated thyroid carcinoma
    Won Gu Kim
    Department of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Korea
    J Clin Endocrinol Metab 93:4683-9. 2008
  5. doi request reprint The prognostic value of the metastatic lymph node ratio and maximal metastatic tumor size in pathological N1a papillary thyroid carcinoma
    Min Ji Jeon
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Republic of Korea
    Eur J Endocrinol 168:219-25. 2013
  6. pmc Long-term clinical outcome of differentiated thyroid cancer patients with undetectable stimulated thyroglobulin level one year after initial treatment
    Ji Min Han
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Thyroid 22:784-90. 2012
  7. doi request reprint Clinical outcomes of persistent radioiodine uptake in the neck shown by diagnostic whole body scan in patients with differentiated thyroid carcinoma after initial surgery and remnant ablation
    Eui Young Kim
    Department of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Songpa Gu, Seoul 138 736, Korea
    Clin Endocrinol (Oxf) 73:257-63. 2010
  8. doi request reprint Coexistence of chronic lymphocytic thyroiditis is associated with lower recurrence rates in patients with papillary thyroid carcinoma
    Eui Young Kim
    Department of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Seoul, S Korea
    Clin Endocrinol (Oxf) 71:581-6. 2009
  9. ncbi request reprint Papillary thyroid carcinoma arising from a thyroglossal duct cyst: a single institution experience
    Yun Mi Choi
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138 736, Korea
    Endocr J 60:665-70. 2013
  10. doi request reprint Time trend in tumour size and characteristics of anaplastic thyroid carcinoma
    Ji Min Han
    Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 77:459-64. 2012

Detail Information

Publications84

  1. pmc Prognostic parameters for recurrence of papillary thyroid microcarcinoma
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    BMC Cancer 8:296. 2008
    ..Papillary thyroid microcarcinoma (PTMC) is defined as a papillary thyroid carcinoma less than or equal to 1.0 cm in size. Independent prognostic factors for clinical recurrence of PTMC have not been clearly delineated...
  2. ncbi request reprint The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 65:364-8. 2006
    ..While some reports suggest the BRAF(V600E) mutation is associated with factors predicting a poor prognosis and recurrence, this remains a controversial issue...
  3. doi request reprint Serum epidermal growth factor is associated with prognosis and hormone receptor status in patients with HER2-positive metastatic breast cancer treated with first-line trastuzumab plus taxane chemotherapy
    Ji Won Kim
    Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak Ro, Jongno gu, Seoul, 110 744, Korea
    Cancer Chemother Pharmacol 72:1023-9. 2013
    ..In this study, we investigated the clinical and pathologic implications of serum EGF levels in patients with HER2-positive metastatic breast cancer (MBC)...
  4. doi request reprint Change of serum antithyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin-negative patients with differentiated thyroid carcinoma
    Won Gu Kim
    Department of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Korea
    J Clin Endocrinol Metab 93:4683-9. 2008
    ..The change in TgAb concentration measured between the time of remnant ablation (TgAb1) and 6-12 months thereafter (TgAb2) was also evaluated as a possible prognostic indicator...
  5. doi request reprint The prognostic value of the metastatic lymph node ratio and maximal metastatic tumor size in pathological N1a papillary thyroid carcinoma
    Min Ji Jeon
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Republic of Korea
    Eur J Endocrinol 168:219-25. 2013
    ..Moreover, the significance of the size of metastatic tumors in LNs has not been clarified. This study was to evaluate the impact of the extent of LN metastasis and size of metastatic tumors on the recurrence in pathological N1a PTC...
  6. pmc Long-term clinical outcome of differentiated thyroid cancer patients with undetectable stimulated thyroglobulin level one year after initial treatment
    Ji Min Han
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Thyroid 22:784-90. 2012
    ....
  7. doi request reprint Clinical outcomes of persistent radioiodine uptake in the neck shown by diagnostic whole body scan in patients with differentiated thyroid carcinoma after initial surgery and remnant ablation
    Eui Young Kim
    Department of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Songpa Gu, Seoul 138 736, Korea
    Clin Endocrinol (Oxf) 73:257-63. 2010
    ....
  8. doi request reprint Coexistence of chronic lymphocytic thyroiditis is associated with lower recurrence rates in patients with papillary thyroid carcinoma
    Eui Young Kim
    Department of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Seoul, S Korea
    Clin Endocrinol (Oxf) 71:581-6. 2009
    ..We evaluated the influence of coexistent CLT on prognostic outcome and the association of coexistent CLT with clinicopathological parameters...
  9. ncbi request reprint Papillary thyroid carcinoma arising from a thyroglossal duct cyst: a single institution experience
    Yun Mi Choi
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138 736, Korea
    Endocr J 60:665-70. 2013
    ..If these tests reveal a suspected lesion in the thyroid or lymph node, SO/TT and lymph node dissection should be performed...
  10. doi request reprint Time trend in tumour size and characteristics of anaplastic thyroid carcinoma
    Ji Min Han
    Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 77:459-64. 2012
    ..We evaluated the time trend of characteristics of ATC such as size and association with coexistent differentiated thyroid carcinoma (DTC). We also found the characteristics of patients showing long-term survival...
  11. doi request reprint Adjuvant radioactive therapy after reoperation for locoregionally recurrent papillary thyroid cancer in patients who initially underwent total thyroidectomy and high-dose remnant ablation
    Ji Hye Yim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 86 Asanbyeongwongil, Songpa Gu, Seoul 138 736, Korea
    J Clin Endocrinol Metab 96:3695-700. 2011
    ..Little is known, however, about the efficacy of adjuvant radioactive iodine (RAI) therapy in these patients...
  12. doi request reprint Empiric high-dose 131-iodine therapy lacks efficacy for treated papillary thyroid cancer patients with detectable serum thyroglobulin, but negative cervical sonography and 18F-fluorodeoxyglucose positron emission tomography scan
    Won Gu Kim
    Department of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Korea
    J Clin Endocrinol Metab 95:1169-73. 2010
    ....
  13. doi request reprint Effects of different doses of radioactive iodine for remnant ablation on successful ablation and on long-term recurrences in patients with differentiated thyroid carcinoma
    Eui Young Kim
    Department of aInternal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul
    Nucl Med Commun 32:954-9. 2011
    ..The aim of this study was to compare ablation success and disease-free survival (DFS) on the basis of different ablation doses...
  14. pmc Long-term consequence of elevated thyroglobulin in differentiated thyroid cancer
    Ji Hye Yim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Thyroid 23:58-63. 2013
    ....
  15. doi request reprint Serum antithyroglobulin antibodies interfere with thyroglobulin detection in fine-needle aspirates of metastatic neck nodes in papillary thyroid carcinoma
    Min Ji Jeon
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Korea
    J Clin Endocrinol Metab 98:153-60. 2013
    ..However, it is not clear whether serum anti-Tg antibodies (TgAbs) interfere with the detection of Tg in needle washout fluids from FNAs (FNA-Tg)...
  16. doi request reprint Technical and oncologic safety of robotic thyroid surgery
    Onvox Yi
    Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Ann Surg Oncol 20:1927-33. 2013
    ..The aim of this study was to evaluate the surgical outcomes of a double-incision robot-assisted gasless transaxillary thyroidectomy procedure compared with conventional open thyroid surgery...
  17. ncbi request reprint 18F-fluorodeoxyglucose positron emission tomography does not predict malignancy in thyroid nodules cytologically diagnosed as follicular neoplasm
    Jung Min Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Korea
    J Clin Endocrinol Metab 92:1630-4. 2007
    ..The objective of this study was to evaluate the usefulness of (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) in predicting malignancy in thyroid nodules cytologically diagnosed as follicular neoplasm...
  18. doi request reprint Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer
    Sae Won Han
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    Int J Cancer 132:2209-16. 2013
    ..006). In conclusion, concurrent methylation of NEUROG1 and CDKN2A (p16) is associated with recurrence following adjuvant FOLFOX in Stages II/III colorectal cancer...
  19. pmc Association between expression of X-linked inhibitor of apoptosis protein and the clinical outcome in a BRAF V600E-prevalent papillary thyroid cancer population
    Ji Hye Yim
    1 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Thyroid 24:689-94. 2014
    ..In the present study, we evaluated the potential role of XIAP expression as a novel prognostic marker to predict recurrence, in combination with the BRAF(V600E) mutational status...
  20. doi request reprint Diagnostic accuracy of ultrasound and 18-F-FDG PET or PET/CT for patients with suspected recurrent papillary thyroid carcinoma
    Jin Woo Choi
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Ultrasound Med Biol 36:1608-15. 2010
    ..1%, 71.7% and 69.6% vs. 55.3%, 56.6%, and 52.2%). PET added diagnostic information in a limited number of patients with negative results on neck US (3 with neck recurrence and 2 with distant metastasis)...
  21. doi request reprint Intramedullary spinal cord metastasis from papillary thyroid carcinoma
    Min Ji Jeon
    Department of Internal Medicine, University of Ulsan College of Medicine, Songpa Gu, Seoul, Korea
    Thyroid 21:1269-71. 2011
    ..Here we report a patient with progressive lower leg weakness due to ISCM from papillary thyroid carcinoma who had a good response to surgery...
  22. doi request reprint HER2/CEP17 ratio and HER2 immunohistochemistry predict clinical outcome after first-line trastuzumab plus taxane chemotherapy in patients with HER2 fluorescence in situ hybridization-positive metastatic breast cancer
    Ji Won Kim
    Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak Ro, Jongno gu, Seoul, 110 744, Korea
    Cancer Chemother Pharmacol 72:109-15. 2013
    ....
  23. doi request reprint Characteristic ultrasound feature of traumatic neuromas after neck dissection: direct continuity with the cervical plexus
    Eun Ju Ha
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Thyroid 22:820-6. 2012
    ..The purpose of this study was to evaluate the ultrasound (US) features that differentiate traumatic neuroma from recurrent lymphadenopathy after lateral neck dissection (LND), focusing on direct continuity with the involved nerve...
  24. doi request reprint Association between STAT1 activity and BRAF mutations in papillary thyroid carcinomas
    Ji Hye Yim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    J Surg Oncol 106:719-23. 2012
    ..The present study evaluated the activity of STAT1 in human papillary thyroid carcinomas (PTC)...
  25. pmc Expression of X-linked inhibitor of apoptosis protein in neoplastic thyroid disorder
    Ji Hye Yim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    J Korean Med Sci 26:1191-5. 2011
    ..Moreover, high XIAP expression in conventional PTC is strongly associated with reduced risk of lateral neck lymph node metastasis...
  26. ncbi request reprint Serum thyroglobulin levels at the time of 131I remnant ablation just after thyroidectomy are useful for early prediction of clinical recurrence in low-risk patients with differentiated thyroid carcinoma
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Korea
    J Clin Endocrinol Metab 90:1440-5. 2005
    ....
  27. doi request reprint The outcomes of first reoperation for locoregionally recurrent/persistent papillary thyroid carcinoma in patients who initially underwent total thyroidectomy and remnant ablation
    Ji Hye Yim
    Departments of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138 736, Korea
    J Clin Endocrinol Metab 96:2049-56. 2011
    ..The primary treatment of locoregionally recurrent/persistent papillary thyroid cancer (PTC) is surgical removal by reoperation. However, there had been only limited number of reports on the outcome of reoperation...
  28. pmc Sub-Classification of Lateral Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma by Pathologic Criteria
    Min Ji Jeon
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    PLoS ONE 10:e0133625. 2015
    ..However, many patients have favorable prognosis even with pathologic N1b patients in clinical practice. The study aims to identify high- and intermediate-risk groups based on initial pathologic characteristics in these patients...
  29. doi request reprint Initial clinical experience with BRAF(V600E) mutation analysis of core-needle biopsy specimens from thyroid nodules
    Sang Hyun Choi
    Department of Radiology and the Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa Gu, Seoul, Korea
    Clin Endocrinol (Oxf) 84:607-13. 2016
    ....
  30. doi request reprint Changing trends in the clinicopathological features and clinical outcomes of medullary thyroid carcinoma
    Hyemi Kwon
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    J Surg Oncol 113:152-8. 2016
    ..However, recent changes of medullary thyroid carcinoma (MTC) over time remain unclear. We evaluated changes of the clinicopathological characteristics and clinical outcomes in patients with MTC in recent years...
  31. doi request reprint Association between neck ultrasonographic findings and clinico-pathological features in the follicular variant of papillary thyroid carcinoma
    Eun Kyung Jang
    Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 83:968-76. 2015
    ..Clinical outcomes of FVPTC are variable depending on the subtypes. This study evaluated the association of pre-operative ultrasonographic (US) findings and clinico-pathological features of FVPTC...
  32. doi request reprint Recent Changes in the Clinical Outcome of Papillary Thyroid Carcinoma With Cervical Lymph Node Metastasis
    Min Ji Jeon
    Departments of Internal Medicine M J J, W G K, Y M C, H K, T Y K, Y K S, W B K, Pathology D E S, Surgery Y M L, T Y S, J H Y, S J H, K W C, Radiology J H B, J H L, and Nuclear Medicine J S R, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138 736, Korea
    J Clin Endocrinol Metab 100:3470-7. 2015
    ..The number and size of metastatic LNs were proposed as new prognostic factors in PTC with cervical LN metastasis (N1)...
  33. pmc Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells
    Ahrum Min
    Cancer Research Institute, Seoul National University College of Medicine, Seoul, 110 799, Korea
    Breast Cancer Res 17:33. 2015
    ..Based on this, HDAC inhibition could be predicted to enhance the anti-tumor effect of PARP inhibitors in cancer cells by blocking the HRR pathway...
  34. doi request reprint Features Predictive of Distant Metastasis in Papillary Thyroid Microcarcinomas
    Min Ji Jeon
    1 Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea
    Thyroid 26:161-8. 2016
    ..However, PTMCs may be associated with distant metastasis. This study aimed to evaluate the clinicopathological features and identify the risk factors for distant metastasis in patients with PTMCs...
  35. doi request reprint Differentiating the location of cervical lymph node metastasis is very useful for estimating the risk of distant metastases in papillary thyroid carcinoma
    Min Ji Jeon
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 81:593-9. 2014
    ..The aim of this study was to evaluate the risk of distant metastases according to the tumour size and LN status in PTC patients, with special consideration of the LN metastasis pattern...
  36. doi request reprint A cut-off value of basal serum calcitonin for detecting macroscopic medullary thyroid carcinoma
    Hyemi Kwon
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 82:598-603. 2015
    ..Serum calcitonin (CT) level is used to detect medullary thyroid carcinoma (MTC), but the cut-off level is unclear. We aimed at identifying the optimal cut-off value of basal serum CT levels for detecting MTC...
  37. doi request reprint Thyroglobulin level in fine-needle aspirates for preoperative diagnosis of cervical lymph node metastasis in patients with papillary thyroid carcinoma: two different cutoff values according to serum thyroglobulin level
    Min Ji Jeon
    1 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Thyroid 25:410-6. 2015
    ..However, the cutoff value of FNA-Tg in the preoperative state is not defined clearly. This study aimed to evaluate the optimal cutoff value of preoperative FNA-Tg according to serum Tg level...
  38. ncbi request reprint Redifferentiation therapy with 13-cis retinoic acids in radioiodine-resistant thyroid cancer
    Won Gu Kim
    Department of Endocrinology and Metabolism, University of Ulsan College of Medicine, Seoul, Korea
    Endocr J 56:105-12. 2009
    ..13-cis RA partially restores I-131 uptake in few patients with recurrent or metastatic DTC. The use of 13-cis RA in current protocol has only limited usefulness and is not routinely recommended as currently used protocol...
  39. doi request reprint Concurrent occurrence of medullary thyroid carcinoma and papillary thyroid carcinoma in the same thyroid should be considered as coincidental
    Won Gu Kim
    Department of Endocrinology and Metabolism, Asan Medical Centre, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Korea
    Clin Endocrinol (Oxf) 72:256-63. 2010
    ..In this study, we evaluated the prevalence and characteristics of patients with concurrent MTC and PTC. Design Retrospective analysis of patients with MTC in a single centre and review of the literature...
  40. doi request reprint Obesity is a risk factor for thyroid cancer in a large, ultrasonographically screened population
    Ji Min Han
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    Eur J Endocrinol 168:879-86. 2013
    ..We conducted this study to determine whether obesity is a risk factor for thyroid cancer by systematically screening a selected population by ultrasonography...
  41. doi request reprint Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line
    Hyun Jeung Choi
    Asan Institute for Life Science, Asan Medical Center, University of Ulsan College of Medicine, Songpa Gu, Seoul 138 736, South Korea
    Nucl Med Biol 39:1275-80. 2012
    ..Our objective was to assess the effect of alpha-lipoic acid (ALA), known as potential antioxidant, on expression of sodium iodide symporter in thyroid cancer cells...
  42. ncbi request reprint The BRAF mutation is not associated with poor prognostic factors in Korean patients with conventional papillary thyroid microcarcinoma
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 63:588-93. 2005
    ..The BRAF(V600E) mutation, the most common genetic alteration reported in papillary thyroid carcinoma, has been associated with poor prognostic factors...
  43. ncbi request reprint 18F-fluorodeoxyglucose uptake in thyroid from positron emission tomogram (PET) for evaluation in cancer patients: high prevalence of malignancy in thyroid PET incidentaloma
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Laryngoscope 115:1074-8. 2005
    ....
  44. ncbi request reprint Prognostic factors for Korean patients with anaplastic thyroid carcinoma
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Head Neck 29:765-72. 2007
    ..We wished to determine the prognostic factors of survival and effect of treatment on survival rate in patients with ATC...
  45. ncbi request reprint Lymphovascular invasion is associated with lateral cervical lymph node metastasis in papillary thyroid carcinoma
    Jung Min Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Laryngoscope 116:2081-5. 2006
    ..The objective of this retrospective study to evaluate whether lymphovascular invasion (LVI) is associated with lateral cervical lymph node metastasis and tumor recurrence in papillary thyroid carcinoma (PTC)...
  46. ncbi request reprint Susceptible alleles of the CD40 and CTLA-4 genes are not associated with the relapse after antithyroid withdrawal in Graves' disease
    Kyung Won Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Thyroid 17:1229-34. 2007
    ..These findings suggest that the genetic markers associated with the development of GD cannot be used to predict the relapse of GD patients in place of clinical parameters...
  47. doi request reprint Negative Expression of CPSF2 Predicts a Poorer Clinical Outcome in Patients with Papillary Thyroid Carcinoma
    Tae Yon Sung
    1 Department of Surgery, University of Ulsan College of Medicine, Seoul, Korea
    Thyroid 25:1020-5. 2015
    ..This study aimed at evaluating CPSF2 protein expression as a prognostic marker for PTC in a region with a high prevalence of the BRAF(V600E) mutation, Korea...
  48. doi request reprint Clinical course and prognostic factors in patients with malignant pheochromocytoma and paraganglioma: A single institution experience
    Yun Mi Choi
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    J Surg Oncol 112:815-21. 2015
    ..This study aimed to evaluate prognostic factors associated with the survival of malignant PCC/PG...
  49. pmc ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy
    Hee Jun Kim
    Department of Internal Medicine, Chung Ang University College of Medicine, Seoul, Korea
    Cancer Sci 106:86-93. 2015
    ..Our results also suggest that the prediction of docetaxel toxicity might be possible for C3435T polymorphism. This study results provides valuable information on individualized therapy according to genotypes. ..
  50. doi request reprint Core needle biopsy can minimise the non-diagnostic results and need for diagnostic surgery in patients with calcified thyroid nodules
    Eun Ju Ha
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon gil, Songpa Gu, Seoul, 138 736, Korea
    Eur Radiol 24:1403-9. 2014
    ..To evaluate the role of core needle biopsy (CNB) for calcified thyroid nodules...
  51. pmc Low levels of serum vitamin D3 are associated with autoimmune thyroid disease in pre-menopausal women
    Yun Mi Choi
    1 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Thyroid 24:655-61. 2014
    ..We evaluated the association of serum vitamin D levels with the prevalence of autoimmune thyroid disease (AITD)...
  52. pmc Effects of low-dose and high-dose postoperative radioiodine therapy on the clinical outcome in patients with small differentiated thyroid cancer having microscopic extrathyroidal extension
    Ji Min Han
    1 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
    Thyroid 24:820-5. 2014
    ..We evaluated success rates and long-term clinical outcomes of patients with DTC of small tumor size, microscopic ETE, and no cervical lymph node (LN) metastasis treated either with a low (1.1 GBq) or high RAI dose (5.5 GBq)...
  53. pmc Follicular and Hurthle cell carcinoma of the thyroid in iodine-sufficient area: retrospective analysis of Korean multicenter data
    Won Gu Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Korean J Intern Med 29:325-33. 2014
    ..In this study we evaluated the clinical behavior, prognostic factors and treatment outcomes of FTC and HCC in Korea...
  54. doi request reprint Thyroid nodules with initially nondiagnostic cytologic results: the role of core-needle biopsy
    Jin Sun Yeon
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon gil, Songpa Gu, Seoul 138 736, Korea
    Radiology 268:274-80. 2013
    ..To evaluate the role of core-needle biopsy (CNB) in thyroid nodules with nondiagnostic results at previous fine-needle aspiration (FNA)...
  55. pmc Skeletal Muscle Depletion Predicts the Prognosis of Patients with Advanced Pancreatic Cancer Undergoing Palliative Chemotherapy, Independent of Body Mass Index
    Younak Choi
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    PLoS ONE 10:e0139749. 2015
    ..We investigated whether sarcopenia at diagnosis and loss of skeletal muscle during palliative chemotherapy were associated with survival in patients with pancreatic cancer...
  56. pmc More Accurate Prediction of Metastatic Pancreatic Cancer Patients' Survival with Prognostic Model Using Both Host Immunity and Tumor Metabolic Activity
    Younak Choi
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    PLoS ONE 11:e0145692. 2016
    ..We investigated NLR and maximum SUV (SUVmax) as prognostic markers in metastatic pancreatic cancer (MPC) patients who receive palliative chemotherapy...
  57. pmc The Impact of Diabetes Mellitus and Metformin Treatment on Survival of Patients with Advanced Pancreatic Cancer Undergoing Chemotherapy
    Younak Choi
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    Cancer Res Treat 48:171-9. 2016
    ..However, in patients with advanced pancreatic cancer (APC) who receive palliative chemotherapy, the impact of DM on the prognosis of APC is unclear...
  58. pmc NRAS codon 61 mutation is associated with distant metastasis in patients with follicular thyroid carcinoma
    Eun Kyung Jang
    1 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Thyroid 24:1275-81. 2014
    ..Furthermore, we elucidated the relationship between RAS mutations and clinical outcomes in FTC patients...
  59. doi request reprint KRAS mutation is associated with worse prognosis in stage III or high-risk stage II colon cancer patients treated with adjuvant FOLFOX
    Dae Won Lee
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    Ann Surg Oncol 22:187-94. 2015
    ..The purpose of this study was to assess the prognostic impact of KRAS and BRAF mutation in patients treated with adjuvant 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX)...
  60. pmc Changes in the pulmonary function test after radioactive iodine treatment in patients with pulmonary metastases of differentiated thyroid cancer
    Eun Kyung Jang
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138 736, Korea Division of Endocrinology, Dongnam Institute of Radiological and Medical Sciences Cancer Center, Busan, Korea
    PLoS ONE 10:e0125114. 2015
    ....
  61. doi request reprint Ultrasound elastography for thyroid nodules: a reliable study?
    Jae Kyun Kim
    Department of Radiology, Chung Ang University College of Medicine, Seoul, Korea
    Ultrasound Med Biol 38:1508-13. 2012
    ..Substantial interobserver (κ = 0.738) and intraobserver agreement were observed in reliable USE results (κ = 0.765). Clinical application of USE should be restricted to the thyroid nodules with reliable results...
  62. doi request reprint Optimal Patient Selection for Trastuzumab Treatment in HER2-Positive Advanced Gastric Cancer
    Chan Young Ock
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    Clin Cancer Res 21:2520-9. 2015
    ..However, not all patients with HER2-positive AGC seem to benefit from trastuzumab. We evaluated the association between treatment outcomes with trastuzumab and HER2 status in patients with HER2-positive AGC...
  63. doi request reprint Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells
    Ahrum Min
    Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Breast Cancer Res 17:534. 2015
    ..Based on this, HDAC inhibition could be predicted to enhance the anti-tumor effect of PARP inhibitors in cancer cells by blocking the HRR pathway...
  64. doi request reprint Efficacy and safety of radiofrequency ablation for treating locoregional recurrence from papillary thyroid cancer
    Hyun Kyung Lim
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon gil, Songpa Gu, Seoul, 138 736, Korea
    Eur Radiol 25:163-70. 2015
    ..To assess the efficacy and safety of ultrasound- (US) guided radiofrequency ablation (RFA) for controlling locoregional recurrent papillary thyroid cancer (PTC) in a large patient population...
  65. doi request reprint The impact of body mass index dynamics on survival of patients with advanced pancreatic cancer receiving chemotherapy
    Younak Choi
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea
    J Pain Symptom Manage 48:13-25. 2014
    ..However, in patients with advanced PC (APC), especially those receiving palliative chemotherapy, the impact of BMI on survival has not been investigated fully...
  66. pmc Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing
    Sae Won Han
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    PLoS ONE 8:e64271. 2013
    ..Targeted sequencing platform using NGS technology is feasible for clinical use and provides comprehensive genetic alteration data...
  67. doi request reprint Ataxia-telangiectasia-mutated protein expression with microsatellite instability in gastric cancer as prognostic marker
    Jin Won Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University, Seoul, Korea
    Int J Cancer 134:72-80. 2014
    ..Taken together, these findings indicate that ATM expression with MSI status is an independent factor for gastric cancer prognosis in gastric cancer patients who received curative surgery...
  68. doi request reprint Cystic versus predominantly cystic thyroid nodules: efficacy of ethanol ablation and analysis of related factors
    Young Joong Kim
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon gil, Songpa Gu, Seoul, 138 736, South Korea
    Eur Radiol 22:1573-8. 2012
    ..To compare the efficacy of ethanol ablation (EA) of cystic and predominantly cystic thyroid nodules, and to evaluate factors affecting efficacy...
  69. ncbi request reprint Metastasis to the thyroid diagnosed by fine-needle aspiration biopsy
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 62:236-41. 2005
    ..Metastasis to the thyroid is uncommon, but the number of cases seems to have increased in recent years. This increase may be related to more frequent use of fine-needle aspiration biopsy (FNAB) in any suspected case...
  70. doi request reprint The influence of the BRAF V600E mutation in thyroid cancer cell lines on the anticancer effects of 5-aminoimidazole-4-carboxamide-ribonucleoside
    Hyun Jeung Choi
    Asan Institute for Life Science, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon gil, Songpa Gu, Seoul 138 736, Republic of Korea
    J Endocrinol 211:79-85. 2011
    ..Thus, regulation of AMPK activity may be potentially useful as a therapy for thyroid cancer if the cancer harbors a BRAF V600E mutation...
  71. ncbi request reprint Completion thyroidectomy in patients with thyroid cancer who initially underwent unilateral operation
    Eun Sook Kim
    Department of Internal Medicine, Ulsan University Hospital, Ulsan, Korea
    Clin Endocrinol (Oxf) 61:145-8. 2004
    ..Many patients have separate cancers in the contralateral lobe and in these cases completion thyroidectomy is essential even though primary tumour is small and limited within thyroid...
  72. ncbi request reprint Clinical characteristics of primary thyroid lymphoma in Koreans
    You Cheol Hwang
    Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Endocr J 56:399-405. 2009
    ..The patients with MALT lymphoma were more frequently presented with early stage diseases and this might lead to the favorable outcome to treatments than those with DLBCL...
  73. doi request reprint Efficacy of infusional 5-fluorouracil, doxorubicin, and mitomycin-C (iFAM) in the treatment of patients with gemcitabine-pretreated pancreatic cancer and analysis of prognostic factors in a salvage setting
    Kyu Hyoung Lim
    Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul, 110 744, Korea
    Cancer Chemother Pharmacol 68:1017-26. 2011
    ....
  74. ncbi request reprint Ultrasonographic screening for detection of thyroid cancer in patients with Graves' disease
    Won Bae Kim
    Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 60:719-25. 2004
    ....
  75. pmc The effect of 5-aminoimidazole-4-carboxamide-ribonucleoside was mediated by p38 mitogen activated protein kinase signaling pathway in FRO thyroid cancer cells
    Won Gu Kim
    Division of Endocrinology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Korean J Intern Med 29:474-81. 2014
    ..In the present study, we investigated the effect of activating AMPK by 5-aminoimidazole-4-carboxamide-ribonucleotide (AICAR) in thyroid cancer cells...
  76. pmc Body mass index is not associated with treatment outcomes of breast cancer patients receiving neoadjuvant chemotherapy: korean data
    Kyung Hun Lee
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea Cancer Research Institute, Seoul National University, Seoul, Korea
    J Breast Cancer 15:427-33. 2012
    ..The purpose of this study was to evaluate the predictive or prognostic value of obesity in breast cancer receiving neoadjuvant chemotherapy...
  77. ncbi request reprint Systemic inflammatory syndrome and hepatic inflammatory cell infiltration caused by an interleukin-6 producing pheochromocytoma
    Jeong Min Kang
    Department of Internal Medicine, University of Ulsan College of Medicine, Songpa Gu, Seoul, Korea
    Endocr J 52:193-8. 2005
    ..The adrenal tumor was densely immunostained with antibody to IL-6. After resection of his adrenal tumor, his serum IL-6 level returned to normal (11 pg/ml) and all symptoms subsided with normalization of laboratory findings...
  78. pmc Efficacy of exemestane in korean patients with metastatic breast cancer after failure of nonsteroidal aromatase inhibitors
    June Koo Lee
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    J Breast Cancer 16:66-71. 2013
    ..Exemestane has shown good efficacy and tolerability in postmenopausal women with hormone receptor-positive metastatic breast cancer. However, clinical outcomes in Korean patients have not yet been reported...
  79. doi request reprint Relationship between serum free T4 (FT4) levels and metabolic syndrome (MS) and its components in healthy euthyroid subjects
    Beom Jun Kim
    Department of Internal Medicine and Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 70:152-60. 2009
    ..While some reports suggest that MS and/or insulin resistance is associated with low serum free T4 (FT4) level in euthyroid subjects, this remains a controversial issue...
  80. pmc Is routine central neck dissection necessary for the treatment of papillary thyroid microcarcinoma?
    Se Jun Choi
    Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    Clin Exp Otorhinolaryngol 1:41-5. 2008
    ..To determine the necessity for routine CND in PTMC patients, we reviewed the clinicopathologic and laboratory data of the patients of PTMC...
  81. ncbi request reprint Arg16Gly polymorphism in beta2-adrenergic receptor gene is not associated with thyrotoxic periodic paralysis in Korean male patients with Graves' disease
    Tae Yong Kim
    Department of Internal Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea
    Clin Endocrinol (Oxf) 62:585-9. 2005
    ..beta2-adrenergic receptors (ADRB2s) are expressed in skeletal muscle and stimulate the sodium pump. Single nucleotide polymorphisms in ADRB2 gene were identified and may act as disease modifiers in various diseases...
  82. ncbi request reprint Association of HLA-DR and -DQ genes with Graves disease in Koreans
    Myoung Hee Park
    Department of Laboratory Medicine, Seoul National University College of Medicine and Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Hum Immunol 66:741-7. 2005
    ..Although HLA class II alleles associated with GD in Koreans were different from those in Caucasians, some associations are shared, such as association of DRB1*0301 in male patients and protective effect of DRB1*0701 to GD susceptibility...
  83. doi request reprint Phase II study of biweekly S-1 and oxaliplatin combination chemotherapy in metastatic colorectal cancer and pharmacogenetic analysis
    Junshik Hong
    Department of Internal Medicine, Seoul National University Hospital, 101 Daehang ro, Jongno gu, Seoul, Korea
    Cancer Chemother Pharmacol 67:1323-31. 2011
    ..To evaluate the efficacy and safety of S-1 in combination with oxaliplatin in a biweekly schedule as first-line treatment in metastatic colorectal cancer and the association between genetic polymorphisms and treatment outcomes...