Hyo Soo Kim

Summary

Affiliation: Seoul National University
Country: Korea

Publications

  1. ncbi Multicenter international registry of unprotected left main coronary artery percutaneous coronary intervention with everolimus-eluting stents
    Michael S Lee
    UCLA Medical Center, Los Angeles, CA, USA
    J Invasive Cardiol 24:316-9. 2012
  2. pmc Comparing two-stent strategies for bifurcation coronary lesions: which vessel should be stented first, the main vessel or the side branch?
    Dong Ho Shin
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    J Korean Med Sci 26:1031-40. 2011
  3. pmc Hypoxic priming of mESCs accelerates vascular-lineage differentiation through HIF1-mediated inverse regulation of Oct4 and VEGF
    Sae Won Lee
    Department of Internal Medicine, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Korea
    EMBO Mol Med 4:924-38. 2012
  4. pmc Vascular calcifying progenitor cells possess bidirectional differentiation potentials
    Hyun Ju Cho
    National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea
    PLoS Biol 11:e1001534. 2013
  5. pmc Analysis of potential cost-savings after introduction of drug-eluting balloon angioplasty for in-stent restenosis or small vessel disease
    Kyungil Park
    Cardiovascular Center, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Korean Circ J 41:705-11. 2011
  6. pmc Comparison of Two Different Strategies of Intravascular Ultrasound Guidance during Percutaneous Coronary Intervention; Routine versus Selective
    Jae Bin Seo
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Korean Circ J 43:303-8. 2013
  7. pmc Comparative study of efficacy of dopaminergic neuron differentiation between embryonic stem cell and protein-based induced pluripotent stem cell
    Yoo Wook Kwon
    National Research Laboratory for Stem Cell Niche, Seoul National University Hospital, Seoul, Korea Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
    PLoS ONE 9:e85736. 2014
  8. pmc Celecoxib does not attenuate the antiplatelet effects of aspirin and clopidogrel in healthy volunteers
    Wonjae Lee
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Korean Circ J 40:321-7. 2010
  9. pmc The 'Harmonizing Optimal Strategy for Treatment of coronary artery stenosis - sAfety & effectiveneSS of drug-elUting stents & antiplatelet REgimen' (HOST-ASSURE) trial: study protocol for a randomized controlled trial
    Kyung Woo Park
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, 101 Daehang no, Seoul 110 744, South Korea
    Trials 13:29. 2012
  10. doi Stent coated with antibody against vascular endothelial-cadherin captures endothelial progenitor cells, accelerates re-endothelialization, and reduces neointimal formation
    Woo Hyun Lim
    National Research Laboratory for Stem Cell Niche, Seoul National University Hospital, 101 Daehak Ro, Jongno gu, Seoul, Korea 110 744, Korea
    Arterioscler Thromb Vasc Biol 31:2798-805. 2011

Collaborators

Detail Information

Publications129 found, 100 shown here

  1. ncbi Multicenter international registry of unprotected left main coronary artery percutaneous coronary intervention with everolimus-eluting stents
    Michael S Lee
    UCLA Medical Center, Los Angeles, CA, USA
    J Invasive Cardiol 24:316-9. 2012
    ..The aim of this study was to assess the clinical outcomes of percutaneous coronary intervention (PCI) with everolimus-eluting stents (EES) for the treatment of unprotected left main coronary artery (ULMCA) disease...
  2. pmc Comparing two-stent strategies for bifurcation coronary lesions: which vessel should be stented first, the main vessel or the side branch?
    Dong Ho Shin
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    J Korean Med Sci 26:1031-40. 2011
    ..1% vs 15.9%, retrospectively; P = 0.011). In conclusion, 'A-family' seems preferable to 'S-family' if both approaches are feasible. When two-stent strategy is used, every effort should be made to perform FKI, especially in 'S-family'...
  3. pmc Hypoxic priming of mESCs accelerates vascular-lineage differentiation through HIF1-mediated inverse regulation of Oct4 and VEGF
    Sae Won Lee
    Department of Internal Medicine, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Korea
    EMBO Mol Med 4:924-38. 2012
    ..Collectively, our findings identify that hypoxia enhanced ESC differentiation by HIF-1-mediated inverse regulation of Oct4 and VEGF, which is a novel pathway to promote vascular-lineage differentiation...
  4. pmc Vascular calcifying progenitor cells possess bidirectional differentiation potentials
    Hyun Ju Cho
    National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea
    PLoS Biol 11:e1001534. 2013
    ..These findings suggest that a subtype of BM-derived and vessel-resident progenitor cells offer a therapeutic target for the prevention of vascular calcification and that PPARγ activation may be an option to reverse calcification...
  5. pmc Analysis of potential cost-savings after introduction of drug-eluting balloon angioplasty for in-stent restenosis or small vessel disease
    Kyungil Park
    Cardiovascular Center, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Korean Circ J 41:705-11. 2011
    ..The objective of this study was to predict the expected cost-savings when DEB is substituted for DES in patients with ISR or SVD...
  6. pmc Comparison of Two Different Strategies of Intravascular Ultrasound Guidance during Percutaneous Coronary Intervention; Routine versus Selective
    Jae Bin Seo
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Korean Circ J 43:303-8. 2013
    ..In this study, we compared angiographic result as well as clinical outcomes between two different strategies of IVUS-guidance, the selective vs. the routine...
  7. pmc Comparative study of efficacy of dopaminergic neuron differentiation between embryonic stem cell and protein-based induced pluripotent stem cell
    Yoo Wook Kwon
    National Research Laboratory for Stem Cell Niche, Seoul National University Hospital, Seoul, Korea Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
    PLoS ONE 9:e85736. 2014
    ..The present study demonstrates that P-iPSCs could be a suitable cell source to provide patient-specific therapy for PD without ethical problems or rejection issues. ..
  8. pmc Celecoxib does not attenuate the antiplatelet effects of aspirin and clopidogrel in healthy volunteers
    Wonjae Lee
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Korean Circ J 40:321-7. 2010
    ..However, it is not known whether the administration of celecoxib will attenuate the antiplatelet effects of aspirin and clopidogrel, which are used after stenting. We addressed this gap in our knowledge...
  9. pmc The 'Harmonizing Optimal Strategy for Treatment of coronary artery stenosis - sAfety & effectiveneSS of drug-elUting stents & antiplatelet REgimen' (HOST-ASSURE) trial: study protocol for a randomized controlled trial
    Kyung Woo Park
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, 101 Daehang no, Seoul 110 744, South Korea
    Trials 13:29. 2012
    ..However in Asia, including Korea, the addition of cilostazol (triplet antiplatelet therapy (TAT)) is used more commonly than doubling the dose of clopidogrel in high-risk patients...
  10. doi Stent coated with antibody against vascular endothelial-cadherin captures endothelial progenitor cells, accelerates re-endothelialization, and reduces neointimal formation
    Woo Hyun Lim
    National Research Laboratory for Stem Cell Niche, Seoul National University Hospital, 101 Daehak Ro, Jongno gu, Seoul, Korea 110 744, Korea
    Arterioscler Thromb Vasc Biol 31:2798-805. 2011
    ..In the present study, we evaluated whether anti-VE-cadherin antibody-coated stents (VE-cad stents) might accelerate endothelial recovery and reduce neointimal formation through the ability of capturing EPC...
  11. doi G-CSF- and erythropoietin-based cell therapy: a promising strategy for angiomyogenesis in myocardial infarction
    Hyun Jae Kang
    Innovative Research Institute for Cell Therapy, Department of Internal Medicine, Seoul National University Hospital, 28 Yongun dong, Chongno Gu, Seoul, 110 744, South Korea
    Expert Rev Cardiovasc Ther 6:703-13. 2008
    ..Further studies are required to elucidate the mechanism of action and to improve therapeutic efficacy by employing novel strategies, such as combined cytokines...
  12. doi Six-month versus 12-month dual antiplatelet therapy after implantation of drug-eluting stents: the Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting (EXCELLENT) randomized, multicenter study
    Hyeon Cheol Gwon
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, 101 Daehak Ro, Jongro Gu, Seoul, 110 744, Korea
    Circulation 125:505-13. 2012
    ..We aimed to test whether 6-month DAPT would be noninferior to 12-month DAPT after implantation of drug-eluting stents...
  13. ncbi The essential role of p21 in radiation-induced cell cycle arrest of vascular smooth muscle cell
    Hyo Soo Kim
    Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 744, South Korea
    J Mol Cell Cardiol 37:871-80. 2004
    ..This observation supports the key role of p21 in radiation-induced cell cycle arrest and the degree of p21 expression may be the possible mechanism of radiation failure and delayed restenosis...
  14. pmc Efficacies of the new paclitaxel-eluting Coroflex Please stent in percutaneous coronary intervention; comparison of efficacy between Coroflex Please and Taxus (ECO-PLEASANT) trial: study rationale and design
    Jae Bin Seo
    Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Trials 10:98. 2009
    ..Therefore, prospective, randomized trial is required to demonstrate the non-inferiority of Coroflex Please stent compared with Taxus Liberte stent in a head-to-head manner...
  15. doi Clinical predictors of high posttreatment platelet reactivity to clopidogrel in Koreans
    Kyung Woo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Cardiovasc Ther 30:5-11. 2012
    ..High posttreatment platelet reactivity to clopidogrel (HPPR) is associated with major adverse cardiac events. However, the clinical predictors of HPPR in Asians have not been studied previously...
  16. ncbi CYP3A4 genetic status may be associated with increased vulnerability to the inhibitory effect of calcium-channel blockers on clopidogrel
    Jin Joo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Circ J 77:1289-96. 2013
    ..Studies have shown conflicting results regarding the effect of concomitant CCB administration on clopidogrel response. We investigated the relationship between CYP3A4 genotype and the inhibitory effect of CCBs on clopidogrel response...
  17. ncbi Augmentation of therapeutic angiogenesis using genetically modified human endothelial progenitor cells with altered glycogen synthase kinase-3beta activity
    Jin Ho Choi
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul 110 744, Korea
    J Biol Chem 279:49430-8. 2004
    ..These data provide evidence that GSK3beta has a key role in the angiogenic properties of EPC. Furthermore, the genetic modification of EPC to alter this signaling step can improve the efficacy of cell-based therapeutic vasculogenesis...
  18. ncbi Akt is a key modulator of endothelial progenitor cell trafficking in ischemic muscle
    Jin Hur
    National Research Laboratory for Cardiovascular Stem Cell, Seoul National University College of Medicine, Seoul 110 744, Korea
    Stem Cells 25:1769-78. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  19. ncbi The effect of stem cell mobilization by granulocyte-colony stimulating factor on neointimal hyperplasia and endothelial healing after vascular injury with bare-metal versus paclitaxel-eluting stents
    Hyun Jai Cho
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    J Am Coll Cardiol 48:366-74. 2006
    ....
  20. ncbi Differential effect of intracoronary infusion of mobilized peripheral blood stem cells by granulocyte colony-stimulating factor on left ventricular function and remodeling in patients with acute myocardial infarction versus old myocardial infarction: the
    Hyun Jae Kang
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul 110 744, Republic of Korea
    Circulation 114:I145-51. 2006
    ..In addition, the potential risk of restenosis associated with G-CSF-based stem cell therapy has not been evaluated in the setting of drug eluting stent (DES) implantation...
  21. ncbi Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis
    Jin Hur
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Korea
    Arterioscler Thromb Vasc Biol 24:288-93. 2004
    ..Endothelial progenitor cells (EPC) in one study group is not the same as EPC in other investigators, suggesting that EPC is not a single type of cell population. In this study, we tried to demonstrate the heterogeneity of EPC...
  22. ncbi Intercellular adhesion molecule-1 is upregulated in ischemic muscle, which mediates trafficking of endothelial progenitor cells
    Chang Hwan Yoon
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Arterioscler Thromb Vasc Biol 26:1066-72. 2006
    ..Trafficking of transplanted endothelial progenitor cells (EPCs) to an ischemic organ is a critical step in neovascularization. This study was performed to elucidate the molecular mechanism of EPC trafficking in terms of adhesion molecules...
  23. doi Peroxisome proliferator-activated receptor-δ activates endothelial progenitor cells to induce angio-myogenesis through matrix metallo-proteinase-9-mediated insulin-like growth factor-1 paracrine networks
    Jung Kyu Han
    National Research Laboratory for Cardiovascular Stem Cell, Seoul National University College of Medicine, Seoul, Republic of Korea
    Eur Heart J 34:1755-65. 2013
    ..We investigated the effects of PPAR-δ activation on the paracrine networks between endothelial progenitor cells (EPCs) and endothelial cells (ECs)/skeletal muscle...
  24. ncbi Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases
    Chang Hwan Yoon
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Circulation 112:1618-27. 2005
    ..We also investigated whether the combination of these different cell types shows synergism during neovascularization...
  25. ncbi Beta-catenin overexpression augments angiogenesis and skeletal muscle regeneration through dual mechanism of vascular endothelial growth factor-mediated endothelial cell proliferation and progenitor cell mobilization
    Kwang Il Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Korea
    Arterioscler Thromb Vasc Biol 26:91-8. 2006
    ..However, little is known regarding its role in endothelial cell (EC) and skeletal muscle proliferation and progenitor cell mobilization...
  26. ncbi Mobilized endothelial progenitor cells by granulocyte-macrophage colony-stimulating factor accelerate reendothelialization and reduce vascular inflammation after intravascular radiation
    Hyun Jai Cho
    Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon dong Chongno gu, Seoul 110 744, Korea
    Circulation 108:2918-25. 2003
    ..Endothelial progenitor cells (EPCs) play a pivotal role in repair and regeneration of damaged vessels. We investigated the role of mobilized EPCs in the healing process after intravascular radiation therapy...
  27. ncbi Regulation of endothelial cell and endothelial progenitor cell survival and vasculogenesis by integrin-linked kinase
    Hyun Jai Cho
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Arterioscler Thromb Vasc Biol 25:1154-60. 2005
    ..Integrin-linked kinase (ILK) plays a pivotal role in ECM-mediated signaling. Therefore, we investigated the role of ILK in ECs and EPCs during neovascularization...
  28. doi Priming with angiopoietin-1 augments the vasculogenic potential of the peripheral blood stem cells mobilized with granulocyte colony-stimulating factor through a novel Tie2/Ets-1 pathway
    Min Seok Kim
    National Research Laboratory for Cardiovascular Stem Cell, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul 110 744, Korea
    Circulation 120:2240-50. 2009
    ....
  29. pmc Study design and rationale of 'Influence of Cilostazol-based triple anti-platelet therapy on ischemic complication after drug-eluting stent implantation (CILON-T)' study: A multicenter randomized trial evaluating the efficacy of Cilostazol on ischemic vas
    Seung Pyo Lee
    Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Trials 11:87. 2010
    ..It is also controversial whether there is a significant interaction between lipophilic statin and clopidogrel...
  30. ncbi NF-kappaB decoy potentiates the effects of radiation on vascular smooth muscle cells by enhancing apoptosis
    Shu ying Zhang
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul 110 744, Korea
    Exp Mol Med 37:18-26. 2005
    ....
  31. ncbi Thalidomide as a potent inhibitor of neointimal hyperplasia after balloon injury in rat carotid artery
    Seung Jung Park
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Arterioscler Thromb Vasc Biol 24:885-91. 2004
    ..Thalidomide, because of its potent antiinflammatory and immunomodulatory properties, is being re-evaluated in several clinical fields. Therefore, we examined whether thalidomide therapy affects neointimal formation...
  32. doi Comparison of neointimal hyperplasia and peri-stent vascular remodeling after implantation of everolimus-eluting versus sirolimus-eluting stents: intravascular ultrasound results from the EXCELLENT study
    Young Guk Ko
    Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University Health System, 50 Yonsei ro, Seodaemun gu, Seoul, 120 752, Korea
    Int J Cardiovasc Imaging 29:1229-36. 2013
    ..001) were observed less frequently with EES than SES. EES and SES were similarly effective in reducing neointimal hyperplasia. However, positive peri-stent vascular remodeling and LASM occurred less frequently with EES than SES...
  33. ncbi Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clinical
    Hyun Jae Kang
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea
    Lancet 363:751-6. 2004
    ..We examined the feasibility and efficacy of granulocyte-colony stimulating factor (G-CSF) therapy and subsequent intracoronary infusion of collected peripheral blood stem-cells (PBSCs) in such patients...
  34. pmc HMG-CoA reductase inhibitor improves endothelial dysfunction in spontaneous hypertensive rats via down-regulation of caveolin-1 and activation of endothelial nitric oxide synthase
    Jung Won Suh
    Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea
    J Korean Med Sci 25:16-23. 2010
    ..These results imply the therapeutic strategies for the high blood pressure-associated endothelial dysfunction through modifying caveolin status...
  35. ncbi Association between cardiac valvular calcification and coronary artery disease in a low-risk population
    Hyung Kwan Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Coron Artery Dis 15:1-6. 2004
    ..This study was performed to determine whether MAC or AVSC is also associated with, and has a power to predict, CAD in Koreans as in Caucasians...
  36. ncbi Constitutively active glycogen synthase kinase-3beta gene transfer sustains apoptosis, inhibits proliferation of vascular smooth muscle cells, and reduces neointima formation after balloon injury in rats
    Kyung Woo Park
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Korea
    Arterioscler Thromb Vasc Biol 23:1364-9. 2003
    ..Glycogen synthase kinase (GSK)-3beta is a crucial factor in many cellular signaling pathways and may play an important role in smooth muscle proliferation and apoptosis after angioplasty...
  37. doi FOXO1 impairs whereas statin protects endothelial function in diabetes through reciprocal regulation of Kruppel-like factor 2
    Hae Young Lee
    National Research Laboratory of Cardiovascular Stem Cell Niche, Seoul, Korea
    Cardiovasc Res 97:143-52. 2013
    ..This study was designed to evaluate the reciprocal regulation of KLF2 by the forkhead transcription factor FOXO1, and the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor atorvastatin, in hyperglycaemic conditions...
  38. pmc Clinical characteristics of coronary drug-eluting stent fracture: insights from a two-center des registry
    Kyung Woo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    J Korean Med Sci 26:53-8. 2011
    ..In conclusion, SF is associated with increased rates of restenosis and repeat revascularization. Significant risk factors include chronic kidney disease, RCA intervention, and SES use...
  39. doi Final kissing ballooning and long-term clinical outcomes in coronary bifurcation lesions treated with 1-stent technique: results from the COBIS registry
    Hyeon Cheol Gwon
    Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Heart 98:225-31. 2012
    ..Whether final kissing ballooning (FKB) is mandatory in the 1-stent technique is uncertain...
  40. pmc Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion
    Jun Bean Park
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    PLoS ONE 6:e28327. 2011
    ..Also, this PPAR-γ agonist reversed the paclitaxel-induced aggravation of TF expression, which suggests a possibility that the benefits might outweigh its risks in a group of patients with paclitaxel-eluting stent implanted...
  41. doi Adjunctive cilostazol versus double-dose clopidogrel after drug-eluting stent implantation: the HOST-ASSURE randomized trial (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis-Safety & Effectiveness of Drug-Eluting Stents & An
    Kyung Woo Park
    Seoul National University Hospital, Seoul, Republic of Korea
    JACC Cardiovasc Interv 6:932-42. 2013
    ..This study sought to test the noninferiority of triple antiplatelet therapy (TAT) versus double-dose clopidogrel dual antiplatelet therapy (DDAT) in patients undergoing percutaneous coronary intervention (PCI)...
  42. ncbi Association between plasma lipids, and apolipoproteins and coronary artery disease: a cross-sectional study in a low-risk Korean population
    Hyung Kwan Kim
    Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Chongno Gu, South Korea
    Int J Cardiol 101:435-40. 2005
    ....
  43. ncbi Long-term clinical outcomes of dissections after intracoronary beta-radiation with rhenium-188-diethylene triamine penta-acetic acid-filled balloon system
    Kwang Il Kim
    Cardiovascular Center, Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, 28 YeonGun Dong, Chongno Gu, Seoul, South Korea
    Int J Cardiol 104:190-6. 2005
    ..Little is known about the effect of radiation on dissection resolution and the late clinical outcome of dissection after brachytherapy...
  44. ncbi Celecoxib, a cyclooxygenase-2 inhibitor, reduces neointimal hyperplasia through inhibition of Akt signaling
    Han Mo Yang
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Circulation 110:301-8. 2004
    ..Here, we examined the effects of celecoxib on neointimal formation after balloon injury and its mechanism of action...
  45. ncbi N-terminal pro-B-type natriuretic peptide as a predictor of repeat coronary revascularization
    Jung Ju Sir
    Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Center, Seoul Paik Hospital, South Korea
    Int J Cardiol 126:322-32. 2008
    ..However, little is known about the value of NT-proBNP as a predictor of repeat revascularization (RR) at follow-up angiography in patients with normal LV systolic function...
  46. doi Generation of human secondary cardiospheres as a potent cell processing strategy for cell-based cardiac repair
    Hyun Jai Cho
    Cardiovascular Center and Department of Internal Medicine, Seoul National University Hospital, 101 Daehak Ro, Jongno gu, Seoul, Republic of Korea
    Biomaterials 34:651-61. 2013
    ..These results demonstrate that generation of secondary CSs from a small quantity of adult human cardiac tissue is a feasible and effective cell processing strategy to improve the therapeutic efficacy of cell therapy...
  47. doi Enhanced clopidogrel responsiveness in smokers: smokers' paradox is dependent on cytochrome P450 CYP1A2 status
    Kyung Woo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Arterioscler Thromb Vasc Biol 31:665-71. 2011
    ..We examined whether genetic variations in the cytochrome and drug transporter system are associated with the effect of smoking on clopidogrel response...
  48. doi Comparison of hyperemic efficacy between central and peripheral venous adenosine infusion for fractional flow reserve measurement
    Myung Ki Seo
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Circ Cardiovasc Interv 5:401-5. 2012
    ..We performed this prospective study to evaluate the feasibility and efficacy of peripheral intravenous infusion of adenosine for FFR measurement...
  49. ncbi Benefit of complete revascularization in patients with multivessel coronary disease in the drug-eluting stent era
    Jin Wook Chung
    Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Circ J 76:1624-30. 2012
    ..The benefit of complete (CR) vs. incomplete revascularization (IR) with drug-eluting stent (DES), unlike with bypass grafting, is not well established in patients with multivessel coronary artery disease (MVD)...
  50. ncbi High plasma interleukin-6 is associated with drug-eluting stent thrombosis: possible role of inflammatory cytokines in the development of stent thrombosis from the Korea Stent Thrombosis Registry
    Seok Jae Hwang
    Cardiovascular Center, Seoul National University Main Hospital, Seoul 110 744, Korea
    Circ J 75:1350-7. 2011
    ..Inflammation might contribute to the development of stent thrombosis (ST). The association between inflammatory cytokine concentrations and drug-eluting ST were evaluated...
  51. ncbi Characteristics and predictors of drug-eluting stent thrombosis: results from the multicenter 'Korea Stent Thrombosis (KoST)' registry
    Kyung Woo Park
    Cardiovascular Center, Seoul National University Main Hospital, Seoul, Korea
    Circ J 75:1626-32. 2011
    ..Previous studies have reported possible predictors of drug-eluting stent thrombosis (ST), but data for Asians are relatively limited. This study was performed to elucidate clinical predictors of ST in Koreans...
  52. doi Multicenter randomized trial evaluating the efficacy of cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease: results of the CILON-T (influence of CILostazol-based triple antiplatelet therapy ON is
    Jung Won Suh
    Cardiovascular Center, Seoul National University Hospital, Korea
    J Am Coll Cardiol 57:280-9. 2011
    ..We aimed to test whether cilostazol has beneficial effects in the real-world patients treated with intracoronary drug-eluting stents (DES)...
  53. ncbi Long-term clinical outcome of chronic total occlusive lesions treated with drug-eluting stents: comparison of sirolimus-eluting and paclitaxel-eluting stents
    Seung Pyo Lee
    Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Circ J 74:693-700. 2010
    ..There are few studies comparing the efficacy of different drug-eluting stents and their long-term clinical outcomes in percutaneous coronary intervention (PCI) of chronic total occlusive (CTO) lesions...
  54. pmc Secondary sphere formation enhances the functionality of cardiac progenitor cells
    Hyun Jai Cho
    Cardiovascular Center and Department of Internal Medicine, Seoul National University, Seoul, Korea
    Mol Ther 20:1750-66. 2012
    ..These results provide a simple strategy for enhancing cellular potency for cardiac repair. Furthermore, this strategy may be implemented to other types of stem/progenitor cell-based therapy...
  55. ncbi Involvement of E-selectin in recruitment of endothelial progenitor cells and angiogenesis in ischemic muscle
    Il Young Oh
    Department of Internal Medicine, Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
    Blood 110:3891-9. 2007
    ..But this impaired vasculogenesis was rescued by sE-selectin. In conclusion, these data demonstrate E-selectin is a pivotal molecule for EPCs' homing to ischemic limb and vasculogenesis...
  56. doi Sirolimus- versus paclitaxel-eluting stents for the treatment of coronary bifurcations results: from the COBIS (Coronary Bifurcation Stenting) Registry
    Young Bin Song
    Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Am Coll Cardiol 55:1743-50. 2010
    ..We aimed to compare the long-term clinical outcomes of patients treated with sirolimus-eluting stents (SES) or paclitaxel-eluting stents (PES) for coronary bifurcation lesions...
  57. pmc Snail as a potential target molecule in cardiac fibrosis: paracrine action of endothelial cells on fibroblasts through snail and CTGF axis
    Sae Won Lee
    Department of Internal Medicine and Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
    Mol Ther 21:1767-77. 2013
    ..Our findings suggested a new mechanism of cell-to-cell communication between EndMT-like cells and fibroblasts for fibrosis induction and implicated Snail as a potential target molecule in cardiac fibrosis after I/R injury...
  58. ncbi Physiologic assessment of jailed side branch lesions using fractional flow reserve
    Bon Kwon Koo
    Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Cardiovascular Center and Cardiovascular Research Institute, Seoul National University Hospital, Seoul, Republic of Korea
    J Am Coll Cardiol 46:633-7. 2005
    ....
  59. ncbi Sirolimus-eluting stent showed better one-year outcomes than paclitaxel-eluting stent in a real life setting of coronary intervention in Koreans
    Jung Won Suh
    Department of Internal Medicine, Seoul National University College of Medicine, Korea
    Int J Cardiol 117:31-6. 2007
    ..Therefore, we investigated the clinical and angiographic outcomes of these two types of the DES...
  60. ncbi Effects of beta-radiation with a 188rhenium-filled balloon catheter system on non-stented adjacent coronary artery segments
    Bon Kwon Koo
    Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Cardiovascular Center and Cardiovascular Research Institute, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul 110 744, South Korea
    Int J Cardiol 96:73-7. 2004
    ..The effects of beta-radiation with a (188)rhenium ((188)Re)-filled balloon catheter system on angiographically normal reference segments have not been well defined...
  61. doi Noninvasive diagnosis of ischemia-causing coronary stenosis using CT angiography: diagnostic value of transluminal attenuation gradient and fractional flow reserve computed from coronary CT angiography compared to invasively measured fractional flow reser
    Yeonyee E Yoon
    Department of Medicine, Seoul National University Hospital, Seoul, Korea
    JACC Cardiovasc Imaging 5:1088-96. 2012
    ....
  62. ncbi Hepatic lipase C514T polymorphism and its relationship with plasma HDL-C levels and coronary artery disease in Koreans
    Kyung Woo Park
    Cardiovascular Laboratory, Clinical Research Center, Seoul National University Hospital, and Department of Internal Medicine, Seoul National University College of Medicine, Korea
    J Biochem Mol Biol 36:237-42. 2003
    ..However, our data does not suggest an association between the polymorphism and an increased risk of CAD...
  63. pmc PPARγ modulates vascular smooth muscle cell phenotype via a protein kinase G-dependent pathway and reduces neointimal hyperplasia after vascular injury
    Han Mo Yang
    1 National Research Laboratory for Stem Cell Niche, Seoul National University College of Medicine, Seoul, Korea 2 Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea 3 Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
    Exp Mol Med 45:e65. 2013
    ..This activation of PKG by rosiglitazone results in reduced neointimal hyperplasia after angioplasty. These results provide important mechanistic insight into the cardiovascular-protective effect of PPARγ. ..
  64. doi New mechanism of rosiglitazone to reduce neointimal hyperplasia: activation of glycogen synthase kinase-3beta followed by inhibition of MMP-9
    Choon Soo Lee
    Innovative Research Institute for Cell Therapy IRICT, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
    Arterioscler Thromb Vasc Biol 29:472-9. 2009
    ..But the underlying mechanism has not been clarified. In this study, we examined how rosiglitazone inhibited neointimal hyperplasia...
  65. doi Enhanced clopidogrel response in smokers is reversed after discontinuation as assessed by VerifyNow assay: additional evidence for the concept of 'smokers' paradox'
    Kyung Woo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Heart 98:1000-6. 2012
    ..No study has shown reversal of enhanced clopidogrel response after smoking cessation...
  66. ncbi Effects of acute hyperglycemia on endothelium-dependent vasodilation in patients with diabetes mellitus or impaired glucose metabolism
    Sang Hyun Kim
    Department of Internal Medicine, Seoul National University, College of Medicine, Seoul, Korea
    Endothelium 10:65-70. 2003
    ....
  67. pmc Angiopoietin-1 protects heart against ischemia/reperfusion injury through VE-cadherin dephosphorylation and myocardiac integrin-β1/ERK/caspase-9 phosphorylation cascade
    Sae Won Lee
    Department of Internal Medicine, and Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
    Mol Med 17:1095-106. 2011
    ..Our findings suggest the novel cardioprotective mechanisms of angiopoietin-1 that are achieved by reducing both vascular leakage and cardiomyocyte death after ischemia/reperfusion injury...
  68. ncbi Forkhead transcription factor FOXO3a is a negative regulator of angiogenic immediate early gene CYR61, leading to inhibition of vascular smooth muscle cell proliferation and neointimal hyperplasia
    Hae Young Lee
    National Research Laboratory for Cardiovascular Stem Cell, Seoul National University Hospital, Korea
    Circ Res 100:372-80. 2007
    ..These data suggest that FOXO3a is a negative transcription factor of CYR61 and that suppression of CYR61 is among several mechanisms by which FOXO3a inhibits VSMC proliferation and neointimal hyperplasia...
  69. doi Prevention of radiocontrast medium-induced nephropathy using short-term high-dose simvastatin in patients with renal insufficiency undergoing coronary angiography (PROMISS) trial--a randomized controlled study
    Sang Ho Jo
    Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine Cardiovascular Center, Seoul National University Hospital, Seoul, South Korea
    Am Heart J 155:499.e1-8. 2008
    ..We investigated to determine whether simvastatin pretreatment reduces the risk of contrast-induced nephropathy in a high-risk population of patients with renal insufficiency undergoing coronary angiography...
  70. doi Randomized trial comparing the efficacy between different types of paclitaxel-eluting stents: the comparison of efficacy between COroflex PLEASe ANd Taxus stent (ECO-PLEASANT) randomized controlled trial
    Jae Bin Seo
    Seoul National University Boramae Medical Center, Seoul, Korea
    Am Heart J 165:733-43. 2013
    ..Coroflex Please (B Braun, Melsungen, Germany) is a newly developed PES. We compared the clinical and angiographic efficacy of Coroflex Please with Taxus Liberte (Boston Scientific, Natick, MA) in a real-world practice...
  71. doi Effects of celecoxib on restenosis after coronary intervention and evolution of atherosclerosis (Mini-COREA) trial: celecoxib, a double-edged sword for patients with angina
    Hyun Jae Kang
    Seoul National University Hospital, Seoul, Republic of Korea
    Eur Heart J 33:2653-61. 2012
    ..We aimed to confirm the effects of 3-month celecoxib in patients receiving drug-eluting stent (DES) implantation in the larger prospective, randomized trial...
  72. doi Everolimus-eluting stent implantation for unprotected left main coronary artery stenosis. The PRECOMBAT-2 (Premier of Randomized Comparison of Bypass Surgery versus Angioplasty Using Sirolimus-Eluting Stent in Patients with Left Main Coronary Artery Disea
    Young Hak Kim
    University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    JACC Cardiovasc Interv 5:708-17. 2012
    ..This study sought to evaluate the safety and efficacy of second-generation drug-eluting stents (DES) for patients with unprotected left main coronary artery (ULMCA) stenosis...
  73. doi Amlodipine, clopidogrel and CYP3A5 genetic variability: effects on platelet reactivity and clinical outcomes after percutaneous coronary intervention
    Kyung Woo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Korea
    Heart 98:1366-72. 2012
    ..In the presence of CYP3A4 inhibitors such as amlodipine, the genetic variation of CYP3A5, the isoenzyme responsible for the backup CYP3A activity, may play an important role in clopidogrel activation...
  74. doi Sirolimus- vs. paclitaxel-eluting stents for the treatment of unprotected left main coronary artery stenosis: complete 2-year follow-up of a two-center registry
    Kyung Woo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Republic of Korea
    Int J Cardiol 151:89-95. 2011
    ..We compared the mid-to long-term outcome between sirolimus-(SES) vs. paclitaxel-eluting stents (PES) in an all-comer analysis that included all patients with unprotected LMCA stenosis who underwent PCI with SES or PES...
  75. ncbi Intracoronary infusion of the mobilized peripheral blood stem cell by G-CSF is better than mobilization alone by G-CSF for improvement of cardiac function and remodeling: 2-year follow-up results of the Myocardial Regeneration and Angiogenesis in Myocardi
    Hyun Jae Kang
    National Research Laboratory for Cardiovascular Stem Cell, Seoul National University Hospital, Seoul, Republic of Korea
    Am Heart J 153:237.e1-8. 2007
    ..We reported 2 years of follow-up results of 2 different strategies of G-CSF-based stem cell therapy...
  76. doi Everolimus-eluting versus sirolimus-eluting stents in patients undergoing percutaneous coronary intervention: the EXCELLENT (Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting) randomized trial
    Kyung Woo Park
    Cardiovascular Center, Seoul National University Main Hospital, Chongno Gu, Seoul, Korea
    J Am Coll Cardiol 58:1844-54. 2011
    ..The goal of this study was to compare the angiographic outcomes of everolimus-eluting stents (EES) and sirolimus-eluting stents (SES) in a head-to-head manner...
  77. doi Clinical outcomes of high on-treatment platelet reactivity in Koreans receiving elective percutaneous coronary intervention (from results of the CROSS VERIFY study)
    Kyung Woo Park
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Korea
    Am J Cardiol 108:1556-63. 2011
    ..In conclusion, HOPR to clopidogrel was significantly associated with cardiac death and spontaneous MI after elective PCI, suggesting that clopidogrel response variability may be a significant risk factor of hard end points in Koreans...
  78. ncbi Activated forkhead transcription factor inhibits neointimal hyperplasia after angioplasty through induction of p27
    Kyung Woo Park
    Cardiovascular Laboratory, Clinical Research Institute, Seoul National University Hospital, Korea
    Arterioscler Thromb Vasc Biol 25:742-7. 2005
    ..Furthermore, we tested whether FKHRL1 overexpression can inhibit neointimal hyperplasia in a rat carotid artery model...
  79. ncbi Two-year clinical follow-up results of intracoronary radiation therapy with rhenium-188-diethylene triamine penta-acetic acid-filled balloon
    Young Seok Cho
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
    Catheter Cardiovasc Interv 63:274-81. 2004
    ..The benefit was noted only in a small subgroup of patients with in-stent restenosis...
  80. ncbi Beta-catenin overexpression reduces myocardial infarct size through differential effects on cardiomyocytes and cardiac fibroblasts
    Joo Yong Hahn
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110 744, Korea
    J Biol Chem 281:30979-89. 2006
    ..beta-Catenin may play an important role in the healing process after MI by promoting survival and cell cycle not only in cardiomyocytes but also in cardiac fibroblasts with its differentiation into myofibroblasts...
  81. doi Serum alkaline phosphatase is a predictor of mortality, myocardial infarction, or stent thrombosis after implantation of coronary drug-eluting stent
    Jun Bean Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, 101 Daehak Ro, Jongro Gu, Seoul 110 744, Republic of Korea
    Eur Heart J 34:920-31. 2013
    ..The aim of this study was to examine the prognostic value of the ALP level in patients with CAD who underwent PCI with drug-eluting stent (DES)...
  82. doi Five-year results of intracoronary infusion of the mobilized peripheral blood stem cells by granulocyte colony-stimulating factor in patients with myocardial infarction
    Hyun Jae Kang
    Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, 101 Daehak Ro, Jongro Gu, Seoul 110 744, South Korea
    Eur Heart J 33:3062-9. 2012
    ..To evaluate the long-term effects of peripheral blood stem cell therapy in myocardial infarction (MI) patients...
  83. pmc Paraoxonase 1 gene polymorphism does not affect clopidogrel response variability but is associated with clinical outcome after PCI
    Kyung Woo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    PLoS ONE 8:e52779. 2013
    ..We evaluated whether genetic variation of PON-1 is associated with clinical outcome in a large cohort of Korean patients with drug-eluting stents implantation...
  84. doi Cilostazol attenuates on-treatment platelet reactivity in patients with CYP2C19 loss of function alleles receiving dual antiplatelet therapy: a genetic substudy of the CILON-T randomised controlled trial
    Kyung Woo Park
    Cardiovascular Center, Seoul National University Main and Bundang Hospital, Seoul, Korea
    Heart 97:641-7. 2011
    ..To evaluate whether the addition of cilostazol to dual antiplatelet therapy (DAT, aspirin plus clopidogrel) can attenuate clopidogrel on-treatment platelet reactivity (OPR) in patients with the CYP2C19 loss-of-function (LOF) allele...
  85. doi Cotreatment with darbepoetin and granulocyte colony-stimulating factor is efficient to recruit proangiogenic cell populations in patients with acute myocardial infarction
    Hyun Jae Kang
    Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    Cell Transplant 21:1055-61. 2012
    ..Combination treatment with darbepoetin and G-CSF is safe and more efficient to mobilize and recruit proangiogenic cells than G-CSF alone in patients with AMI. (..
  86. doi Sex differences in management and mortality of patients with ST-elevation myocardial infarction (from the Korean Acute Myocardial Infarction National Registry)
    Si Hyuck Kang
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Bundang Hospital, Gyeonggido, Korea
    Am J Cardiol 109:787-93. 2012
    ..The gender effect was accounted for mostly by the women's older age, complex co-morbidities, and severe hemodynamic conditions at presentation...
  87. doi Long-term outcome of adjunctive celecoxib treatment after paclitaxel-eluting stent implantation for the complex coronary lesions: two-year clinical follow-up of COREA-TAXUS trial
    Jin Wook Chung
    Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Circ Cardiovasc Interv 3:243-8. 2010
    ..The objective of this study was to assess the long-term outcome of short-term adjunctive celecoxib treatment after paclitaxel-eluting stent implantation...
  88. ncbi Identification of a novel role of T cells in postnatal vasculogenesis: characterization of endothelial progenitor cell colonies
    Jin Hur
    Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
    Circulation 116:1671-82. 2007
    ..In the present study, we found a subset of T cells that were localized at the center of the EPC colony and played a pivotal role in colony formation and differentiation of early EPCs...
  89. doi Angiographic patterns of restenosis after percutaneous intervention of chronic total occlusive lesions with drug-eluting stents
    Seung Pyo Lee
    Cardiovascular Center, Seoul National University Hospital, Republic of Korea
    Int J Cardiol 156:180-5. 2012
    ..Although the success rate of percutaneous coronary intervention (PCI) of chronic total occlusive (CTO) lesions is rising recently, the nature and behavior of these revascularized lesions in the real-world practice are unknown...
  90. doi Comparison of 5-year clinical outcomes between sirolimus-versus paclitaxel-eluting stent: Korean multicenter network analysis of 9000-patient cohort
    Kyungil Park
    Cardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea
    Circ Cardiovasc Interv 5:174-84. 2012
    ..The long-term effectiveness of DES in unselected people with diabetes is also currently unclear. Moreover, the possibility of late catch-up is suggested in the DES population...
  91. doi Comparison of drug-eluting versus bare-metal stent implantation in ST-elevation myocardial infarction patients with renal insufficiency: results from the national registry in Korea
    Kyung Hee Kim
    Department of Internal Medicine, Seoul National University Hospital, Republic of Korea
    Int J Cardiol 154:71-7. 2012
    ..We aimed to compare the clinical outcomes of BMS versus DES, as well as sirolimus-eluting stents (SES) versus paclitaxel-eluting stents (PES), in STEMI patients with renal insufficiency...
  92. pmc N-cadherin determines individual variations in the therapeutic efficacy of human umbilical cord blood-derived mesenchymal stem cells in a rat model of myocardial infarction
    Eun Ju Lee
    National Research Laboratory for Cardiovascular Stem Cells and IRICT, Seoul National University Hospital, Seoul, Korea
    Mol Ther 20:155-67. 2012
    ..In addition, we observed that DiI-labeled hUCB-MSCs express N-cadherin in the peri-infarct area and interact with cardiomyocytes...
  93. ncbi Inhibitory interaction between calcium channel blocker and clopidogrel. -Efficacy of cilostazol to overcome it-
    Seung Pyo Lee
    Cardiovascular Center, Department of Internal Medicine, Seoul National University Hospital
    Circ J 75:2581-9. 2011
    ..The clinical effect of, and additive measures to overcome the possible inhibitory calcium channel blocker (CCB)-clopidogrel interaction in Asian patients undergoing percutaneous coronary intervention is unknown...
  94. ncbi FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-kappaB
    Hae Young Lee
    Innovative Research Institute for Cell Therapy, Seoul National University Hospital, Seoul, Korea
    Arterioscler Thromb Vasc Biol 28:112-20. 2008
    ..We evaluated the full range effects of FOXO3a in endothelial cells (ECs) by microarray analysis and investigated the role of FOXO3a regulating TNF receptor signaling pathway...
  95. doi Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction
    Joo Yong Hahn
    National Research Laboratory for Cardiovascular Stem Cells, Seoul National University College of Medicine, Seoul, Republic of Korea
    J Am Coll Cardiol 51:933-43. 2008
    ....
  96. ncbi 'Real world' comparison of drug-eluting stents vs bare metal stents in the treatment of unselected patients with acute ST-segment elevation myocardial infarction
    Kyung Woo Park
    Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    Circ J 74:1111-20. 2010
    ..The study aimed to compare the mid- to long-term outcomes of DES vs bare metal stents (BMS) in patients with STEMI in a real-world setting...
  97. pmc Spherical bullet formation via E-cadherin promotes therapeutic potency of mesenchymal stem cells derived from human umbilical cord blood for myocardial infarction
    Eun Ju Lee
    National Research Laboratory for Stem Cell Niche and IRICT, Seoul National University Hospital, Seoul, Korea
    Mol Ther 20:1424-33. 2012
    ....
  98. doi Association of cytochrome P450 2C19*2 polymorphism with clopidogrel response variability and cardiovascular events in Koreans treated with drug-eluting stents
    Il Young Oh
    Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, 28 Yongong dong, Chongno Gu, Seoul, Korea
    Heart 98:139-44. 2012
    ..Although East Asians carry the cytochrome P450 (CYP) 2C19*2 allele more frequently than do Caucasians, the impact of the CYP2C19*2 allele on clopidogrel pharmacodynamics and clinical outcomes is unknown...
  99. doi Paclitaxel- versus sirolimus-eluting stents for treatment of ST-segment elevation myocardial infarction: with analyses for diabetic and nondiabetic subpopulation
    Youngjin Cho
    Cardiovascular Center, Seoul National University Hospital, Seoul, Korea
    JACC Cardiovasc Interv 3:498-506. 2010
    ..The aim of this study was to determine which drug-eluting stent (DES) is preferable for the treatment of ST-segment elevation myocardial infarction (STEMI) and to elucidate the impact of diabetes mellitus on the outcome of each DES...
  100. doi Efficacy of Xience/promus versus Cypher in rEducing Late Loss after stENTing (EXCELLENT) trial: study design and rationale of a Korean multicenter prospective randomized trial
    Kyung Woo Park
    Cardiovascular Center, Seoul National University Main Hospital, Seoul, South Korea
    Am Heart J 157:811-817.e1. 2009
    ....