Jungsil Ro

Summary

Affiliation: National Cancer Center
Country: Korea

Publications

  1. pmc A case of locally advanced breast cancer complicated by pulmonary tumor thrombotic microangiopathy
    Hak Jin Kim
    Department of Cardiology, National Cancer Center, Goyang, Korea
    Cancer Res Treat 44:267-70. 2012
  2. pmc Brain metastases in Asian HER2-positive breast cancer patients: anti-HER2 treatments and their impact on survival
    Y S Yap
    Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore
    Br J Cancer 107:1075-82. 2012
  3. pmc Clinical outcomes of HER2-positive metastatic breast cancer patients with brain metastasis treated with lapatinib and capecitabine: an open-label expanded access study in Korea
    Jungsil Ro
    National Cancer Center Hospital and Research Institute, Goyang, Gyeonggi do 410 769, Republic of Korea
    BMC Cancer 12:322. 2012
  4. pmc The invasive lobular carcinoma as a prototype luminal A breast cancer: a retrospective cohort study
    So Youn Jung
    Center for Breast Cancer, National Cancer Center, Goyang si, Korea
    BMC Cancer 10:664. 2010
  5. pmc Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study
    Jeongseon Kim
    Cancer Epidemiology Branch, Division of Cancer Epidemiology and Management, Research Institute, National Cancer Center, Gyeonggi, South Korea
    BMC Cancer 9:216. 2009
  6. doi request reprint Prognostic Impact of [18F] FDG-PET in operable breast cancer treated with neoadjuvant chemotherapy
    So Youn Jung
    Research Institute and Hospital, National Cancer Center, Goyang si, Gyeonggi Do, Republic of Korea
    Ann Surg Oncol 17:247-53. 2010
  7. doi request reprint Predictive factors of pathologic complete response and clinical tumor progression after preoperative chemotherapy in patients with stage II and III breast cancer
    Jae Heon Jeong
    Center for Clinical Trials, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
    Invest New Drugs 30:408-16. 2012
  8. doi request reprint Phase II parallel group study showing comparable efficacy between premenopausal metastatic breast cancer patients treated with letrozole plus goserelin and postmenopausal patients treated with letrozole alone as first-line hormone therapy
    In Hae Park
    Center for Breast Cancer, National Cancer Center, 323 Ilsan ro, Gyeonggi Do, Korea
    J Clin Oncol 28:2705-11. 2010
  9. doi request reprint A phase Ib study of preoperative lapatinib, paclitaxel, and gemcitabine combination therapy in women with HER2 positive early breast cancer
    In Hae Park
    Center for Breast Cancer, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi Do, 410 769, Korea
    Invest New Drugs 30:1972-7. 2012
  10. doi request reprint Analysis of chemotherapy-induced amenorrhea rates by three different anthracycline and taxane containing regimens for early breast cancer
    Hye Suk Han
    Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, 111 Jungbalsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Korea
    Breast Cancer Res Treat 115:335-42. 2009

Collaborators

Detail Information

Publications60

  1. pmc A case of locally advanced breast cancer complicated by pulmonary tumor thrombotic microangiopathy
    Hak Jin Kim
    Department of Cardiology, National Cancer Center, Goyang, Korea
    Cancer Res Treat 44:267-70. 2012
    ..We report on a patient with locally advanced breast cancer whose course was complicated by fatal PTTM based on clinical and laboratory findings...
  2. pmc Brain metastases in Asian HER2-positive breast cancer patients: anti-HER2 treatments and their impact on survival
    Y S Yap
    Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore
    Br J Cancer 107:1075-82. 2012
    ..We studied the treatment patterns of these patients in Asia to evaluate the impact of anti-HER2 treatment on the time to occurrence of brain metastases (TTBM) and survival after brain metastasis (BM)...
  3. pmc Clinical outcomes of HER2-positive metastatic breast cancer patients with brain metastasis treated with lapatinib and capecitabine: an open-label expanded access study in Korea
    Jungsil Ro
    National Cancer Center Hospital and Research Institute, Goyang, Gyeonggi do 410 769, Republic of Korea
    BMC Cancer 12:322. 2012
    ..To evaluate efficacy in patients with brain metastasis (BM) on entry into the lapatinib expanded access program (LEAP)...
  4. pmc The invasive lobular carcinoma as a prototype luminal A breast cancer: a retrospective cohort study
    So Youn Jung
    Center for Breast Cancer, National Cancer Center, Goyang si, Korea
    BMC Cancer 10:664. 2010
    ..Although the invasive lobular carcinoma (ILC) is the second most frequent histologic subtype in Western countries, its incidence is much lower in Asia, and its characteristics are less well known...
  5. pmc Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study
    Jeongseon Kim
    Cancer Epidemiology Branch, Division of Cancer Epidemiology and Management, Research Institute, National Cancer Center, Gyeonggi, South Korea
    BMC Cancer 9:216. 2009
    ..This study examined the association between fish and fish omega-3 fatty acids intake with the risk of breast cancer in a case-control study of Korean women...
  6. doi request reprint Prognostic Impact of [18F] FDG-PET in operable breast cancer treated with neoadjuvant chemotherapy
    So Youn Jung
    Research Institute and Hospital, National Cancer Center, Goyang si, Gyeonggi Do, Republic of Korea
    Ann Surg Oncol 17:247-53. 2010
    ..This study aimed to evaluate the usefulness of serial [(18)F] 2-fluoro-2-deoxy-D: -glucose-positron emission tomography ([(18)F] FDG-PET) in potentially operable breast cancer with neoadjuvant chemotherapy...
  7. doi request reprint Predictive factors of pathologic complete response and clinical tumor progression after preoperative chemotherapy in patients with stage II and III breast cancer
    Jae Heon Jeong
    Center for Clinical Trials, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
    Invest New Drugs 30:408-16. 2012
    ..This study aimed to define predictive factors of pathologic complete response (pCR) and disease progression in stage II and III breast cancer patients...
  8. doi request reprint Phase II parallel group study showing comparable efficacy between premenopausal metastatic breast cancer patients treated with letrozole plus goserelin and postmenopausal patients treated with letrozole alone as first-line hormone therapy
    In Hae Park
    Center for Breast Cancer, National Cancer Center, 323 Ilsan ro, Gyeonggi Do, Korea
    J Clin Oncol 28:2705-11. 2010
    ..Goserelin and letrozole in premenopausal patients can result in clinical outcomes comparable to those obtained by letrozole alone in postmenopausal patients with metastatic breast cancer (MBC)...
  9. doi request reprint A phase Ib study of preoperative lapatinib, paclitaxel, and gemcitabine combination therapy in women with HER2 positive early breast cancer
    In Hae Park
    Center for Breast Cancer, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi Do, 410 769, Korea
    Invest New Drugs 30:1972-7. 2012
    ..No relationship between lapatinib dose intensity and tumor response was apparent. Median follow-up was 16.2 (range, 6.5-20.7) months. Lapatinib plus paclitaxel and gemcitabine was tolerable with no overlapping toxicity...
  10. doi request reprint Analysis of chemotherapy-induced amenorrhea rates by three different anthracycline and taxane containing regimens for early breast cancer
    Hye Suk Han
    Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, 111 Jungbalsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Korea
    Breast Cancer Res Treat 115:335-42. 2009
    ..Chemotherapy-induced amenorrhea (CIA) by newer taxane-containing regimens was evaluated in early breast cancer (EBC) patients...
  11. doi request reprint Primary systemic therapy with intermittent weekly paclitaxel plus gemcitabine in patients with stage II and III breast cancer: a phase II trial
    Keun Seok Lee
    Center for Breast Cancer, National Cancer Center, 809 Madu 1 dong, Ilsan gu, Goyang si, Gyeonggi Do, 410 769, Republic of Korea
    Invest New Drugs 28:83-90. 2010
    ..In conclusion, PST with intermittent weekly paclitaxel and gemcitabine in patients with stage II/III breast cancer is both well tolerated and effective, showing 18% pCR rate in the breast...
  12. ncbi request reprint Sentinel node identification rate, but not accuracy, is significantly decreased after pre-operative chemotherapy in axillary node-positive breast cancer patients
    Seeyoun Lee
    Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Madu 1 dong 809, Ilsan gu Goyang si, Gyeonggi Do, Korea
    Breast Cancer Res Treat 102:283-8. 2007
    ..The aim was to prove the low identification rate of sentinel lymph node biopsy (SNB) and to determine the feasibility of replacing axillary lymph node dissection (AND) in axillary lymph node positive patients after chemotherapy...
  13. doi request reprint Stage-to-stage comparison of neoadjuvant chemotherapy versus adjuvant chemotherapy in pathological lymph node positive breast cancer patients
    Nam Kwon Lee
    Proton Therapy Center, Research Institute and Hospital, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
    Jpn J Clin Oncol 42:995-1001. 2012
    ....
  14. doi request reprint Social support and depressive mood 1 year after diagnosis of breast cancer compared with the general female population: a prospective cohort study
    Myung Kyung Lee
    Division of Cancer Control, Research Institute, National Cancer Center, 809 Madu dong, Ilsan gu, Goyang si, Gyeonggi Do, 411 769, South Korea
    Support Care Cancer 19:1379-92. 2011
    ..Social support may influence the impact of stressful life events on breast cancer patients' psychological state. However, the precise status of depressive mood in breast cancer during the first year after diagnosis is not yet known...
  15. doi request reprint Metaplastic breast cancer: clinicopathological features and its prognosis
    Hyewon Lee
    Center for Clinical Trials, National Cancer Center, Goyang, Korea
    J Clin Pathol 65:441-6. 2012
    ..The prognosis of metaplastic breast cancer (MBC) is reportedly worse than that of triple-negative invasive ductal carcinoma (TN-IDC), but the determinants of poor prognosis are not yet known...
  16. doi request reprint Locoregional recurrence of breast cancer in patients treated with breast conservation surgery and radiotherapy following neoadjuvant chemotherapy
    Sun Young Min
    Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea Department of Surgery, Kyunghee University, Seoul, Korea
    Int J Radiat Oncol Biol Phys 81:e697-705. 2011
    ..The purpose of this study was to analyze clinical outcomes in patients who exhibited LRR and IBTR after being treated by BCS and RT following NCT...
  17. doi request reprint Phase 2 trial of accelerated, hypofractionated whole-breast irradiation of 39 Gy in 13 fractions followed by a tumor bed boost sequentially delivering 9 Gy in 3 fractions in early-stage breast cancer
    Ja Young Kim
    Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, Korea
    Int J Radiat Oncol Biol Phys 87:1037-42. 2013
    ..To report a phase 2 trial of accelerated, hypofractionated whole-breast irradiation (AH-WBI) delivered as a daily dose of 3 Gy to the whole breast followed by a tumor bed boost...
  18. ncbi request reprint A randomized phase-III trial of docetaxel/capecitabine versus doxorubicin/cyclophosphamide as primary chemotherapy for patients with stage II/III breast cancer
    Keun Seok Lee
    Research Institute and Hospital, National Cancer Center, 809 Madu 1 dong, Ilsan gu, Goyang si, Gyeonggi Do, 410 769, Republic of Korea
    Breast Cancer Res Treat 109:481-9. 2008
    ..Although these findings did not translate into a gain in DFS, the patients who achieved pCR in LN developed significantly less recurrence...
  19. doi request reprint Lack of any association between functionally significant CYP2D6 polymorphisms and clinical outcomes in early breast cancer patients receiving adjuvant tamoxifen treatment
    In Hae Park
    Center for Breast Cancer, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Korea
    Breast Cancer Res Treat 131:455-61. 2012
    ..14; 95% CI 0.68-1.92). This remained the case after subgroup analysis according to different adjuvant treatments. Polymorphisms of CYP2D6 were not associated with clinical outcomes in EBC patients receiving adjuvant tamoxifen treatment...
  20. doi request reprint Worse prognosis of metaplastic breast cancer patients than other patients with triple-negative breast cancer
    So Youn Jung
    Center for Breast Cancer, National Cancer Center, Goyang si, Gyeonggi Do, 410769, Republic of Korea
    Breast Cancer Res Treat 120:627-37. 2010
    ..02) compared to the 473 TN-IDC patients, as reflected by aggressive pathological features. Patients with MBC appeared to have inherently aggressive tumor biology with poorer clinical outcomes than those with general IDC or TN-IDC...
  21. doi request reprint Accumulation of p53 determined by immunohistochemistry as a prognostic marker in node negative breast cancer; analysis according to St Gallen consensus and intrinsic subtypes
    So Youn Jung
    Center for Breast Cancer, National Cancer Center, Goyang, Republic of Korea
    J Surg Oncol 103:207-11. 2011
    ..This study evaluated the prognostic impact of p53 accumulation by immunohistochemistry (IHC) in lymph node-negative breast cancer (LNN-BC), and in subgroups of St Gallen consensus and intrinsic subtypes...
  22. doi request reprint Phase II study of irinotecan plus capecitabine in anthracycline- and taxane- pretreated patients with metastatic breast cancer
    Keun Seok Lee
    Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, 809 Madu 1 dong, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
    Invest New Drugs 31:152-9. 2013
    ..8 %) had grade 3 hand-foot syndrome. The IX combination was effective and tolerable for anthracycline- and taxane-pretreated patients with MBC. A phase III trial of this combination is ongoing...
  23. doi request reprint Comparison of sentinel lymph node biopsy guided by the multimodal method of indocyanine green fluorescence, radioisotope, and blue dye versus the radioisotope method in breast cancer: a randomized controlled trial
    So Youn Jung
    Center for Breast Cancer, National Cancer Center, Goyang, Gyeonggi, Republic of Korea
    Ann Surg Oncol 21:1254-9. 2014
    ....
  24. pmc Breast cancer subtypes and survival in patients with brain metastases
    Byung Ho Nam
    Center for Clinical Trials, National Cancer Center, 111 Jungbalsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
    Breast Cancer Res 10:R20. 2008
    ..Brain metastases (BM) occur in up to one third of patients with metastatic breast cancer (MBC), whose incidences and prognoses by breast cancer subtypes in BM have not been well delineated...
  25. doi request reprint Single nucleotide polymorphisms of CYP19A1 predict clinical outcomes and adverse events associated with letrozole in patients with metastatic breast cancer
    In Hae Park
    Center for Breast Cancer, National Cancer Center, 323 Ilsan ro, Ilsandong gu, Goyang si, Gyeonggi do 410 769, Korea
    Cancer Chemother Pharmacol 68:1263-71. 2011
    ..We evaluated the efficacy of the aromatase inhibitor letrozole in patients with metastatic breast cancer (MBC) as related to DNA polymorphisms of CYP19A1...
  26. doi request reprint Jnk signaling pathway-mediated regulation of Stat3 activation is linked to the development of doxorubicin resistance in cancer cell lines
    Ju Hwa Kim
    Research Institute, National Cancer Center, 809 Madu 1 dong, Ilsan gu, Goyang si, Gyeonggi do 411 764, Republic of Korea
    Biochem Pharmacol 79:373-80. 2010
    ..Taken together, these results indicate that Stat3 activation via the Jnk pathway promotes the resistance of cancer cells to DOX...
  27. pmc Locoregional recurrence of breast conserving surgery after preoperative chemotherapy in korean women with locally advanced breast cancer
    Seeyoun Lee
    Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea
    J Breast Cancer 14:289-95. 2011
    ..mastectomy)...
  28. doi request reprint Phase II study of gemcitabine in combination with vinorelbine versus gemcitabine followed by vinorelbine for metastatic breast cancer
    In Hae Park
    Center for Breast Cancer, National Cancer Center, 111 Jungbalsan ro, Ilsandong gu, Goyang si, Gyeonggi Do, 410 769, Korea
    Invest New Drugs 28:659-69. 2010
    ..No clear data are available concerning the superiority of combination chemotherapy to sequential therapy using agents beyond 1st or 2nd line chemotherapy for treating patients with metastatic breast cancer...
  29. doi request reprint Clinicopathological parameters and biological markers predicting non-sentinel node metastasis in sentinel node-positive breast cancer patients
    Youngmee Kwon
    Research Institute and Hospital, National Cancer Center, Gyeonggi Do, Republic of Korea
    Oncol Rep 25:1063-71. 2011
    ....
  30. doi request reprint Prognostic Implications of Tumor-Infiltrating Lymphocytes in Association With Programmed Death Ligand 1 Expression in Early-Stage Breast Cancer
    In Hae Park
    Center for Breast Cancer, National Cancer Center, Goyang si, Korea Breast and Endocrine Center Branch of Research Institute, National Cancer Center, Goyang si, Korea
    Clin Breast Cancer 16:51-8. 2016
    ..The immune system might influence breast cancer (BC) prognosis. However, the relationship between programmed death ligand 1 (PD-L1) and tumor-infiltrating lymphocyte (TIL) profiles remains unclear with respect to BC subtypes...
  31. doi request reprint Treatment factors affecting breast cancer-related lymphedema after systemic chemotherapy and radiotherapy in stage II/III breast cancer patients
    So Youn Jung
    Center for Breast Cancer, National Cancer Center, 111 Jungbalsan ro, Ilsandong gu, Goyang si, Gyeonggi Do, 410 769, Republic of Korea
    Breast Cancer Res Treat 148:91-8. 2014
    ..07; P = 0.04) were independent risk factors for the LE occurrence. In addition to advanced stage, N-ALNs and SCRT, NAC, and taxane were shown to increase the risk of LE, which could help clinicians identify patients at risk for LE. ..
  32. ncbi request reprint Predicting tissue HER2 status using serum HER2 levels in patients with metastatic breast cancer
    Sun Young Kong
    Research Institute and Hospital, National Cancer Center, Goyang si, Gyeonggi Do, Korea
    Clin Chem 52:1510-5. 2006
    ....
  33. ncbi request reprint Efficacy of exemestane after nonsteroidal aromatase inhibitor use in metastatic breast cancer patients
    Sun Hye Kim
    National Cancer Center, Goyang, Korea
    Asian Pac J Cancer Prev 13:979-83. 2012
    ..Previous studies have suggested a lack of complete cross-resistance between steroidal (exemestane) and non-steroidal aromatase inhibitors (nSAI)...
  34. pmc Potential antitumor effects of nitrogen-containing bisphosphonate in hormone receptor negative breast cancer patients with bone metastases
    In Hae Park
    Center for Breast Cancer, National Cancer Center, Goyang si, Korea
    BMC Cancer 9:154. 2009
    ..This retrospective study evaluated, according to hormone receptor status, the antitumor effects of bisphosphonate especially on survival and disease progression in breast cancer patients with metastatic bone disease...
  35. doi request reprint Dietary mushroom intake and the risk of breast cancer based on hormone receptor status
    Aesun Shin
    National Cancer Center, Goyang si, Gyeonggi do 410 769, Republic of Korea
    Nutr Cancer 62:476-83. 2010
    ..Our results suggest that high consumption of mushrooms might be related to lower risks for breast cancers among premenopausal women; this association may be more robust among women with hormone receptor positive tumors...
  36. doi request reprint Dietary patterns and breast cancer risk in Korean women
    Young Ae Cho
    Cancer Epidemiology Branch, National Cancer Center, Ilsandong gu, Goyang si, Gyeonggi Do, South Korea
    Nutr Cancer 62:1161-9. 2010
    ..These findings indicate that a diet rich in vegetables and seafood is associated with a decreased breast cancer risk in Korean women...
  37. doi request reprint High volumetric breast density predicts risk for breast cancer in postmenopausal, but not premenopausal, Korean Women
    In Hae Park
    Center for Breast Cancer, National Cancer Center, Goyang si, Gyeonggi Do, Korea
    Ann Surg Oncol 21:4124-32. 2014
    ..We investigated the association between mammographic breast density and breast cancer risk in Korean women according to menopausal status and breast cancer subtypes...
  38. doi request reprint Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest
    Won Ki Kim
    Research Institute, National Cancer Center, 809 Madu 1 dong, Ilsan gu, Goyang si, Gyeonggi do 411 764, Republic of Korea
    Invest New Drugs 30:1311-8. 2012
    ..Taken together, the results from our study may contribute to the development of Sal-based therapy for cancer patients treated with P-gp-inhibiting drugs or radiation therapy...
  39. doi request reprint Differential influence of dietary soy intake on the risk of breast cancer recurrence related to HER2 status
    Hae Dong Woo
    Cancer Epidemiology Branch, National Cancer Center, Korea
    Nutr Cancer 64:198-205. 2012
    ..However, further research is needed to confirm these results due to the small number of cancer recurrence events...
  40. doi request reprint Salinomycin sensitizes antimitotic drugs-treated cancer cells by increasing apoptosis via the prevention of G2 arrest
    Ju Hwa Kim
    Research Institute, National Cancer Center, Ilsan gu, Goyang si, Gyeonggi Do, South Korea
    Biochem Biophys Res Commun 418:98-103. 2012
    ..These results may contribute to the development of Sal-based chemotherapy for cancer patients treated with antimitotic drugs...
  41. doi request reprint Concordant HER2 status between metastatic breast cancer cells in CSF and primary breast cancer tissue
    In Hae Park
    Center for Breast Cancer, National Cancer Center, 111 Jeongbalsan ro, Ilsan donggu, Goyang si, Gyeonggi do 410 769, Republic of Korea
    Breast Cancer Res Treat 123:125-8. 2010
    ..When CSF cytology specimens were appropriately prepared and had adequate cellularity without dry artifacts, the CSF cytology was suitable to evaluate HER2 status by FISH analysis in patients with LM...
  42. pmc Protein and lipid MALDI profiles classify breast cancers according to the intrinsic subtype
    Han Sung Kang
    National Cancer Center, Goyang, 410 769, Korea
    BMC Cancer 11:465. 2011
    ..Using recently developed MALDI matrices for lipid profiling, we evaluated whether direct tissue MALDI MS analysis on proteins and lipids may classify human breast cancer samples according to the intrinsic subtype...
  43. ncbi request reprint Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer
    Keun Seok Lee
    Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, 809 Madu 1 dong, Ilsan gu, Goyang si, Gyeonggi do 410 769, Republic of Korea
    Breast Cancer Res Treat 108:241-50. 2008
    ..Genexol-PM appears a promising new paclitaxel in view of significant efficacies. Further trials with different dosing schedules, durations of delivery, or in combination with other drugs are warranted...
  44. doi request reprint Use of a decision aid to help caregivers discuss terminal disease status with a family member with cancer: a randomized controlled trial
    Young Ho Yun
    National Cancer Center, Korea
    J Clin Oncol 29:4811-9. 2011
    ..We tested whether a decision aid explaining how to discuss the approach of death with a family member with cancer would help family caregivers decide to discuss a terminal prognosis...
  45. pmc Impact of Molecular Subtype Conversion of Breast Cancers after Neoadjuvant Chemotherapy on Clinical Outcome
    Siew Kuan Lim
    Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea Breast Service, Department of General Surgery, Changi General Hospital, Singapore
    Cancer Res Treat 48:133-41. 2016
    ..The aim of this study was to examine molecular subtype conversions in patients who underwent neoadjuvant chemotherapy (NAC) and analyze their clinical implications...
  46. doi request reprint SP600125, an inhibitor of Jnk pathway, reduces viability of relatively resistant cancer cells to doxorubicin
    Ju Hwa Kim
    Research Institute, National Cancer Center, 809 Madu 1 dong, Ilsan gu, Goyang si Gyeonggi do, Republic of Korea
    Biochem Biophys Res Commun 387:450-5. 2009
    ..Overall, these results may contribute to the development of chemotherapeutic treatments for patients with DOX-resistant tumors...
  47. pmc Association of polymorphisms and haplotypes in the insulin-like growth factor 1 receptor (IGF1R) gene with the risk of breast cancer in Korean women
    Han Sung Kang
    Center for Breast Cancer, National Cancer Center, Goyang si, Gyeonggi Do, Republic of Korea
    PLoS ONE 9:e84532. 2014
    ..Overall, this case-control study demonstrates statistically significant associations between breast cancer risk and polymorphisms in IGF1R gene. ..
  48. ncbi request reprint Promoter hypomethylation of the N-acetyltransferase 1 gene in breast cancer
    Sun Jung Kim
    Research Institute and Hospital, National Cancer Center, Gyeonggi do 411 764, Korea
    Oncol Rep 19:663-8. 2008
    ..Therefore, hypomethylation of the NAT1 gene plays a significant role in breast carcinogenesis...
  49. pmc Adipokines, insulin resistance, metabolic syndrome, and breast cancer recurrence: a cohort study
    Sang Woo Oh
    Center for Obesity, Nutrition, and Metabolism, Department of Family Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 814 Siksa dong, Ilsandong gu, Goyang si, Gyeonggi Do, 410 773, Korea
    Breast Cancer Res 13:R34. 2011
    ..Several in vitro studies have suggested the effects of adipokines and insulin resistance on breast cancer cell proliferation and survival. However, little is known about the clinical significance of these findings...
  50. ncbi request reprint Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer
    Hyeong Seok Lim
    Research Institute and Hospital, National Cancer Center, Madu1 dong, Ilsan gu, Goyang si, Gyeonggi Do, Republic of Korea
    J Clin Oncol 25:3837-45. 2007
    ..This study assessed the association between genetic polymorphisms of CYP2D6 and PXR, and tamoxifen pharmacokinetics (PK) and clinical outcomes in patients with breast cancer...
  51. pmc Clinical implications of proliferation activity in T1 or T2 male gastric cancer patients
    Young Woo Kim
    Research Institute, National Cancer Center, Goyang, Korea
    Exp Mol Med 47:e193. 2015
    ..The CPCC will help to more precisely classify gastric cancer patients and to select excellent candidates for adjuvant chemotherapy, which in turn will facilitate further clinical chemotherapeutic trials. ..
  52. ncbi request reprint MicroRNA signature for HER2-positive breast and gastric cancer
    Han Sung Kang
    National Cancer Center, Goyang, Republic of Korea
    Anticancer Res 34:3807-10. 2014
    ..In particular, little is known about microRNAs in the human epidermal growth factor receptor 2 (HER2) signaling network...
  53. ncbi request reprint Lipid profiles for HER2-positive breast cancer
    Il Chan Kim
    National Cancer Center, Goyang, Gyeonggi, Republic of Korea
    Anticancer Res 33:2467-72. 2013
    ..We undertook a study to correlate lipid profiles with heterogeneous clinicopathological features of HER2-positive breast cancer...
  54. ncbi request reprint The melanoma antigen gene as a surveillance marker for the detection of circulating tumor cells in patients with breast carcinoma
    Soim Kwon
    Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, South Korea
    Cancer 104:251-6. 2005
    ....
  55. pmc Primary malignant teratoma with a primitive neuroectodermal tumor component in thyroid gland: a case report
    Eunyoung Kim
    Research Institute and Hospital, National Cancer Center, 809 Madu 1 dong, Ilsan gu, Goyang, Korea
    J Korean Med Sci 22:568-71. 2007
    ..This is the first case, to our knowledge, of malignant thyroid teratoma with a exuberant primitive neuroectodermal tumor component in Korea...
  56. doi request reprint Effects of second and subsequent lines of chemotherapy for metastatic breast cancer
    In Hae Park
    Center for Breast Cancer, National Cancer Center, Gyeunggido, Korea
    Clin Breast Cancer 15:e55-62. 2015
    ..We assessed the effect of chemotherapy regimens beyond first-line agents on the clinical outcomes in patients with human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC)...
  57. doi request reprint Identification and clinical implications of circulating microRNAs for estrogen receptor-positive breast cancer
    In Hae Park
    Center for Breast Cancer, National Cancer Center, Madu dong, Ilsandong gu, Goyangsi, South Korea
    Tumour Biol 35:12173-80. 2014
    ..These findings suggest that a circulating tRNA-derived microRNA, miR-1280, is differently expressed in breast cancer patients and may serve as a biomarker for ER-positive breast cancer. ..
  58. pmc Chromatin CKAP2, a new proliferation marker, as independent prognostic indicator in breast cancer
    Han Seong Kim
    Department of Pathology, Inje University Ilsan Paik Hospital, Ilsanseo gu, Goyang, Korea
    PLoS ONE 9:e98160. 2014
    ..In the present study, the prognostic significance of the CKAP2-positive cell count (CPCC), a new proliferation marker, was evaluated, and the results were compared with those for the mitotic activity index (MAI)...
  59. ncbi request reprint Decreased identification rate of sentinel lymph node after neoadjuvant chemotherapy
    Seok Hyung Kang
    Research Institute and Hospital, Center for Breast Cancer, National Cancer Center, Madu 1 dong 809, Ilsan gu, Goyang si, 411 769, Gyeonggi Do, Korea
    World J Surg 28:1019-24. 2004
    ..Thus SLNB can be an alternative to ALND even after neoadjuvant chemotherapy in cases of successful identification of the SLN...
  60. doi request reprint Impact of awareness of terminal illness and use of palliative care or intensive care unit on the survival of terminally ill patients with cancer: prospective cohort study
    Young Ho Yun
    Cancer Management Branch, Research Institute, National Cancer Center, 809, Madu dong, Ilsan gu, Goyang si, Gyeonggi Do, 411 769, Korea
    J Clin Oncol 29:2474-80. 2011
    ..We conducted this study to evaluate the validity of the perception that awareness of their terminal prognosis and use of palliative care or nonuse of an intensive care unit (ICU) causes patients to die sooner than they would otherwise...