Hee Kang

Summary

Affiliation: Kyung Hee University
Country: Korea

Publications

  1. pmc Enzymatically-Processed Wheat Bran Enhances Macrophage Activity and Has in Vivo Anti-Inflammatory Effects in Mice
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyung Hee University, Yongin 17104, Korea
    Nutrients 8:188. 2016
  2. pmc Effect of cinnamon water extract on monocyte-to-macrophage differentiation and scavenger receptor activity
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyunghee University, Yongin, South Korea
    BMC Complement Altern Med 14:90. 2014
  3. doi request reprint Upregulation of interferon-gamma and interleukin-4, Th cell-derived cytokines by So-Shi-Ho-Tang (Sho-Saiko-To) occurs at the level of antigen presenting cells, but not CD4 T cells
    Hee Kang
    Department of Oriental Medical Science, Graduate School of East West Medical Science, Kyunghee University, 1 Seochungdong, Yongin, South Korea
    J Ethnopharmacol 123:6-14. 2009
  4. doi request reprint Suppression of tumour necrosis factor-alpha by Schizonepeta tenuifolia water extract via inhibition of IkappaBalpha degradation and Jun N-terminal kinase/stress-activated protein kinase activation
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyung Hee University, Yongin si, Gyeonggi Do, South Korea
    J Pharm Pharmacol 62:1069-76. 2010
  5. doi request reprint Leuconostoc citreum HJ-P4 (KACC 91035) regulates immunoglobulin E in an ovalbumin-induced allergy model and induces interleukin-12 through nuclear factor-kappa B and p38/c-Jun N-terminal kinases signaling in macrophages
    Hee Kang
    Department of Oriental Medical Science, Graduate School of East West Medical Science, Kyunghee University, Yongin 446 701, South Korea
    Microbiol Immunol 53:331-9. 2009
  6. doi request reprint Immunomodulatory effect of Schizonepeta tenuifolia water extract on mouse Th1/Th2 cytokine production in-vivo and in-vitro
    Hee Kang
    Department of Pathology, College of Oriental Medicine, Kyunghee University, Seoul, 130 710, South Korea
    J Pharm Pharmacol 60:901-7. 2008
  7. doi request reprint Induction of Th1 cytokines by Leuconostoc mesenteroides subsp. mesenteroides (KCTC 3100) under Th2-type conditions and the requirement of NF-kappaB and p38/JNK
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyunghee University, Yongin, South Korea
    Cytokine 46:283-9. 2009
  8. ncbi request reprint Bronchoalveolar lavage eosinophil cationic protein and interleukin-8 levels in acute asthma and acute bronchiolitis
    Chang Keun Kim
    Department of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Korea
    Clin Exp Allergy 35:591-7. 2005
  9. doi request reprint Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation
    Beom Joon Lee
    Department of Internal Medicine, Kangnam Korean Hospital, Kyung Hee University, Seoul, South Korea
    Immunopharmacol Immunotoxicol 33:714-22. 2011
  10. ncbi request reprint Wheeze detection as a measure of bronchial challenge in young children with cough-variant asthma and with classic asthma
    Young Yull Koh
    Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
    Acta Paediatr 96:1223-7. 2007

Collaborators

  • Young Yoo
  • Chang Keun Kim
  • Ho Young Choi
  • Joung Woo Hong
  • Kyung Soo Lee
  • O Jung Kwon
  • Jongmin Lee
  • Choon Sik Park
  • Ji Eun Kim
  • Yun Hee Rhee
  • Young Yull Koh
  • Jinho Yu
  • Ji Hyun Shin
  • So Jung Park
  • Dong Hyung Cho
  • Xiangxue An
  • Dae Ok Kim
  • Jeong Moon Yun
  • Do Kyun Kim
  • Sung Mok Kim
  • Ho Yun Lee
  • Eunjoo H Lee
  • Beom Joon Lee
  • Hoon Ji Jung
  • Jee Hun Park
  • Kyoo Seok Ahn
  • Eu Soo Lim
  • Dae Jin Song
  • Kyu Min Nah
  • Youn Sup Cho
  • Sang Gil Lee
  • Ho Jin Heo
  • Yoon Bum Kim
  • Mahn Kwang Roh
  • Sung Bin Im
  • Sung Hyun Park
  • Kye Won Park
  • Han Al Kwon
  • In Hye Ham
  • In Young Song
  • Young Mog Shim
  • Eun Joo Lee
  • Ji Yun Jeong
  • Chin A Yi
  • Joungho Han
  • Byung Tae Kim
  • Myung Jin Chung
  • Hye Sun Hwang
  • Eun Sung Kim
  • Ji Ho Park
  • Yoon Kyung Jo
  • Nak Won Sohn
  • Min Sook Son
  • Youn Jung Kim
  • Jung Jin Hwang
  • Kyong Nyon Nam
  • Sung Hoon Jun
  • Seung Ha Lee
  • Se Na Kim
  • Jae Hoon You
  • Beom Sang Shim
  • Sung Hoon Kim
  • Hwa Seung Yoo
  • Min Kyu Park
  • Chul Hee Woo
  • Ji Tae Choung
  • Hyung Jin Kim

Detail Information

Publications35

  1. pmc Enzymatically-Processed Wheat Bran Enhances Macrophage Activity and Has in Vivo Anti-Inflammatory Effects in Mice
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyung Hee University, Yongin 17104, Korea
    Nutrients 8:188. 2016
    ..Enzymatically-processed wheat bran boosts macrophage phagocytic capacity possibly through up-regulation of scavenger receptors and confers anti-inflammatory effects, indicating its potential as an immuno-enhancing functional food. ..
  2. pmc Effect of cinnamon water extract on monocyte-to-macrophage differentiation and scavenger receptor activity
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyunghee University, Yongin, South Korea
    BMC Complement Altern Med 14:90. 2014
    ..Our present study investigated whether cinnamon water extract (CWE) may influence the differentiation of monocytes into macrophages and the activity of macrophage scavenger receptors, commonly observed in atherosclerotic lesions...
  3. doi request reprint Upregulation of interferon-gamma and interleukin-4, Th cell-derived cytokines by So-Shi-Ho-Tang (Sho-Saiko-To) occurs at the level of antigen presenting cells, but not CD4 T cells
    Hee Kang
    Department of Oriental Medical Science, Graduate School of East West Medical Science, Kyunghee University, 1 Seochungdong, Yongin, South Korea
    J Ethnopharmacol 123:6-14. 2009
    ..So-Shi-Ho-Tang (SSHT) or known as Sho-Saiko-To in Japanese and Xiao-Chai-Hu-Tang in Chinese has been used to treat chronic liver disease and other infections, and its hepatoprotective effects have been widely studied...
  4. doi request reprint Suppression of tumour necrosis factor-alpha by Schizonepeta tenuifolia water extract via inhibition of IkappaBalpha degradation and Jun N-terminal kinase/stress-activated protein kinase activation
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyung Hee University, Yongin si, Gyeonggi Do, South Korea
    J Pharm Pharmacol 62:1069-76. 2010
    ..The anti-inflammatory effects of an aqueous extract of Schizonepeta tenuifolia on lipopolysaccharide (LPS)-induced tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in vivo and in vitro have been investigated...
  5. doi request reprint Leuconostoc citreum HJ-P4 (KACC 91035) regulates immunoglobulin E in an ovalbumin-induced allergy model and induces interleukin-12 through nuclear factor-kappa B and p38/c-Jun N-terminal kinases signaling in macrophages
    Hee Kang
    Department of Oriental Medical Science, Graduate School of East West Medical Science, Kyunghee University, Yongin 446 701, South Korea
    Microbiol Immunol 53:331-9. 2009
    ..Taken together, the use of L. citreum can be useful in preventing the development and progression of IgE production...
  6. doi request reprint Immunomodulatory effect of Schizonepeta tenuifolia water extract on mouse Th1/Th2 cytokine production in-vivo and in-vitro
    Hee Kang
    Department of Pathology, College of Oriental Medicine, Kyunghee University, Seoul, 130 710, South Korea
    J Pharm Pharmacol 60:901-7. 2008
    ..Our study demonstrates that ST regulates inflammatory responses by reducing the release of Th1 and Th2 cytokines from T cells and prevents unprimed CD4 T cells from differentiating into Th1 and Th2 cells...
  7. doi request reprint Induction of Th1 cytokines by Leuconostoc mesenteroides subsp. mesenteroides (KCTC 3100) under Th2-type conditions and the requirement of NF-kappaB and p38/JNK
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyunghee University, Yongin, South Korea
    Cytokine 46:283-9. 2009
    ..These observations suggest that this microorganism can be a useful Th1-inducing agent in modulating the Th1/Th2 imbalance...
  8. ncbi request reprint Bronchoalveolar lavage eosinophil cationic protein and interleukin-8 levels in acute asthma and acute bronchiolitis
    Chang Keun Kim
    Department of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Korea
    Clin Exp Allergy 35:591-7. 2005
    ....
  9. doi request reprint Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation
    Beom Joon Lee
    Department of Internal Medicine, Kangnam Korean Hospital, Kyung Hee University, Seoul, South Korea
    Immunopharmacol Immunotoxicol 33:714-22. 2011
    ..Cinnamon bark is a very popular herb used in traditional medicine to treat various disorders such as chronic gastric symptoms, arthritis, and the common cold...
  10. ncbi request reprint Wheeze detection as a measure of bronchial challenge in young children with cough-variant asthma and with classic asthma
    Young Yull Koh
    Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
    Acta Paediatr 96:1223-7. 2007
    ....
  11. ncbi request reprint Bronchial responsiveness and serum eosinophil cationic protein levels in preschool children with recurrent wheezing
    Jinho Yu
    Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
    Ann Allergy Asthma Immunol 94:686-92. 2005
    ..Bronchial hyperresponsiveness is a universally recognized phenomenon of asthma, and increased levels of eosinophil cationic protein (ECP) have been identified in the serum of patients with asthma...
  12. ncbi request reprint Immunomodulatory effect of Astragali Radix extract on murine TH1/TH2 cell lineage development
    Hee Kang
    Department of Pathology, College of Oriental Medicine, Kyunghee University, Seoul, South Korea
    Biol Pharm Bull 27:1946-50. 2004
    ..Our data clearly indicates that AR selectively alters Th1/Th2 cytokine secretion patterns and provides the pharmacological basis for AR's clinical applications...
  13. ncbi request reprint Peak expiratory flow variability and exercise responsiveness in methacholine-hyperresponsive adolescents with asthma remission
    Young Yull Koh
    Department of Pediatrics and Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    J Asthma 42:17-23. 2005
    ..50%) of the symptomatic group, and similar to that (5.98 +/- 2.70%) of the control group. Methacholine hyperresponsiveness in asthma remission during adolescence is associated with increased PEF variability but not with increased BRE...
  14. pmc Anti-inflammatory activity of cinnamon water extract in vivo and in vitro LPS-induced models
    Joung Woo Hong
    Graduate School of East West Medical Science, Kyung Hee University, Yongin, Gyeonggi, 446 701, South Korea
    BMC Complement Altern Med 12:237. 2012
    ..The goal of this study is to investigate the in vivo and in vitro inhibitory effect of cinnamon water extract (CWE) on lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α and its underlying intracellular mechanisms...
  15. doi request reprint Regulation of interferon-gamma, interleukin-4 and interleukin-2 by Schizonepeta tenuifolia through differential effects on nuclear factor-kappaB, NFATc2 and STAT4/6
    Hee Kang
    Department of Oriental Medical Science, Graduate School of East West Medicine, Kyunghee University, Yongin, South Korea
    Exp Biol Med (Maywood) 235:230-6. 2010
    ..Further mechanistic work is required to investigate the role of STE on its modulation of anti-CD3-induced cytokines...
  16. pmc Protective effect of the methanol extract from Cryptotaenia japonica Hassk. against lipopolysaccharide-induced inflammation in vitro and in vivo
    Hee Kang
    Graduate School of East West Medical Science, Kyung Hee University, Yongin si, Gyeonggi Do 446 701, South Korea
    BMC Complement Altern Med 12:199. 2012
    ..In this paper, the in vitro and in vivo anti-inflammatory activity of CJ methanol extract was tested using lipopolysaccharide (LPS)-induced inflammatory models...
  17. pmc Distributions of antibody titers to Mycoplasma pneumoniae in Korean children in 2000-2003
    Jinho Yu
    Department of Pediatrics, Dongguk University Interna tional Hospital, Ilsan, Seoul, Korea
    J Korean Med Sci 20:542-7. 2005
    ..During the years 2000-2003, geometric mean antibody titers and the frequencies of high antibody titers varied with time. These changes suggest a cyclic pattern of M. pneumoniae infection, with two epidemic peaks separated by 3 yr...
  18. pmc Prunus yedoensis bark inhibits lipopolysaccharide-induced inflammatory cytokine synthesis by IκBα degradation and MAPK activation in macrophages
    Jeong Moon Yun
    1 Graduate School of East West Medical Science Kyung Hee University, Yongin, South Korea
    J Med Food 17:407-13. 2014
    ..The effects of PYE on inflammatory cytokine synthesis may involve modulation of NF-κB and MAPK activation...
  19. doi request reprint Suppression of autophagy exacerbates Mefloquine-mediated cell death
    Ji Hyun Shin
    Graduate School of East West Medical Science, Kyung Hee University, Gyeoggi Do, Republic of Korea
    Neurosci Lett 515:162-7. 2012
    ..Moreover, suppression of autophagy significantly intensified Mefloquine-mediated cytotoxicity in SH-SY5Y cells. Our findings suggest that suppression of autophagy may exacerbate Mefloquine toxicity in neuroblastoma cells...
  20. ncbi request reprint The chloroform fraction of Solanum nigrum suppresses nitric oxide and tumor necrosis factor-α in LPS-stimulated mouse peritoneal macrophages through inhibition of p38, JNK and ERK1/2
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyung Hee University, Yongin si, Gyeonggi Do, South Korea
    Am J Chin Med 39:1261-73. 2011
    ..The inhibition of iNOS, TNF-α and IL-6 by the chloroform fraction may be partly due to the suppression of p38, JNK and ERK1/2. Further study is required to identify the active compounds of S. nigrum...
  21. doi request reprint Inhibitory effect of Physalis alkekengi L. var. franchetii extract and its chloroform fraction on LPS or LPS/IFN-γ-stimulated inflammatory response in peritoneal macrophages
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyunghee University, Yongin si, Gyeonggi Do 446 701, South Korea
    J Ethnopharmacol 135:95-101. 2011
    ..franchetii (PA) are traditionally used in folk medicine to treat cough, middle ear infection, sore throat, abscesses, and urinary problems. However, the cellular mechanisms underlying PA's possible anti-inflammatory effects are unknown...
  22. doi request reprint Histopathology of lung adenocarcinoma based on new IASLC/ATS/ERS classification: prognostic stratification with functional and metabolic imaging biomarkers
    Ho Yun Lee
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Magn Reson Imaging 38:905-13. 2013
    ....
  23. ncbi request reprint Applicability of interrupter resistance measurements for evaluation of exercise-induced bronchoconstriction in children
    Dae Jin Song
    Department of Pediatrics, Korea University Medical College Hospital, Seoul, Korea
    Pediatr Pulmonol 41:228-33. 2006
    ..Considering that only minimal comprehension and coordination are needed without forced breathing technique, the Rint measurement can provide a useful alternative for assessment of EIB in children unable to perform reliable spirometry...
  24. ncbi request reprint Absence of association of peripheral blood eosinophilia or increased eosinophil cationic protein with bronchial hyperresponsiveness during asthma remission
    Young Yull Koh
    Department of Pediatrics and Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Ann Allergy Asthma Immunol 91:297-302. 2003
    ..The mechanisms responsible for persistent bronchial hyperresponsiveness (BHR) in adolescents with long-term asthma remission are poorly understood...
  25. ncbi request reprint DMNQ S-64 induces apoptosis via caspase activation and cyclooxygenase-2 inhibition in human nonsmall lung cancer cells
    Eu Soo Lim
    O Lab of Angiogenesis and Chemoprevention, College of Oriental Medicine, Kyunghee University, 1 Hoegi dong, Dongdaemun ku, Seoul 131 701, South Korea
    Ann N Y Acad Sci 1095:7-18. 2007
    ..Taken together, DMNQ S-64 may exhibit cytotoxicity against A549 cells via caspase activation and COX-2 inhibition...
  26. ncbi request reprint Exopolysaccharide-overproducing Lactobacillus paracasei KB28 induces cytokines in mouse peritoneal macrophages via modulation of NF-κβ and MAPKs
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyung Hee University, Yongin 446 701, Korea
    J Microbiol Biotechnol 21:1174-8. 2011
    ..paracasei KB28. Our results provide information for a better understanding of molecular mechanisms of the immunomodulatory effect of food-derived EPS-producing lactic acid bacteria...
  27. doi request reprint Indirubin-3'-oxime inhibits inflammatory activation of rat brain microglia
    Hoon Ji Jung
    Graduate School of East West Medical Science, Kyung Hee University, Yongin si 446 701, Republic of Korea
    Neurosci Lett 487:139-43. 2011
    ..These results suggest that indirubin-3'-oxime provides neuroprotection by reducing the productions of various neurotoxic molecules in activated microglia...
  28. doi request reprint Digital tomosynthesis of the thorax: the influence of respiratory motion artifacts on lung nodule detection
    Sung Mok Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Acta Radiol 54:634-9. 2013
    ..However, digital tomosynthesis requires a longer scan time compared with CXR, and thus may be vulnerable to motion artifacts...
  29. ncbi request reprint Bronchoalveolar lavage cytokine profiles in acute asthma and acute bronchiolitis
    Chang Keun Kim
    Department of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Korea
    J Allergy Clin Immunol 112:64-71. 2003
    ..The pathogenetic basis for the relationship between acute bronchiolitis and asthma has not yet been completely elucidated...
  30. ncbi request reprint Effect of an herbal mixture of Cinnamon Cortex, Persicae Semen, and Natril Sulfas on collagen-induced arthritis and lipopolysaccharides-induced nuclear factor-κ B signaling
    Ji Won Lee
    Department of East West Medicine, Graduate School of East West Medical Science, Kyung Hee University, Yongin, 17104, Republic of Korea
    Chin J Integr Med . 2016
    ..To investigate the anti-arthritic and anti-inflammatory effects of the mixture of three herbal agents, Cinnamon Cortex, Persica Semen, and Natril Sulfas (CPN), the major ingredients of Taoren Chengqi Decoction ()...
  31. doi request reprint Antioxidant and Anti-Inflammatory Effects of Various Cultivars of Kiwi Berry (Actinidia arguta) on Lipopolysaccharide-Stimulated RAW 264.7 Cells
    Xiangxue An
    Department of Food Science and Biotechnology, Kyung Hee University, Yongin 17104, Republic of Korea
    J Microbiol Biotechnol 26:1367-74. 2016
    ..Our findings suggest that kiwi berries are potential antioxidant and anti-inflammatory agents. ..
  32. ncbi request reprint Alteration of Energy Metabolism and Antioxidative Processing in the Hippocampus of Rats Reared in Long-Term Environmental Enrichment
    Hee Kang
    Department of East West Medical Science, Graduate School of East West Medical Science, Kyung Hee University, Yongin, South Korea
    Dev Neurosci 38:186-194. 2016
    ..We provide evidence that EE can be developed as a tool to protect the brain from oxidative stress-induced injury...
  33. doi request reprint Use of Gold Nanoparticle Fertilizer Enhances the Ginsenoside Contents and Anti-Inflammatory Effects of Red Ginseng
    Hee Kang
    Graduate School of East West Medical Science, Kyung Hee University, Yongin 17104, Republic of Korea
    J Microbiol Biotechnol 26:1668-1674. 2016
    ..Further research is required to elucidate the causal factors for the gold-induced change in ginsenoside synthesis and to determine the in vivo effect of gold nanoparticle-treated ginseng...
  34. ncbi request reprint Niclosamide induces mitochondria fragmentation and promotes both apoptotic and autophagic cell death
    So Jung Park
    Graduate School of East West Medical Science, Kyung Hee University, Yongin, Korea
    BMB Rep 44:517-22. 2011
    ..Inhibition of autophagy suppressed niclosamide-induced cell death. Therefore, our findings suggest that niclosamide induces mitochondria fragmentation and may contribute to apoptotic and autophagic cell death...
  35. ncbi request reprint Treatment with SI000413, a new herbal formula, ameliorates murine collagen-induced arthritis
    Jee Hun Park
    Life Science RD Center, Sinil Pharmaceutical Co Ltd, Chungju, Republic of Korea
    Biol Pharm Bull 31:1337-42. 2008
    ..These findings suggest that SI000413 is a potential new therapeutic herbal formula for the treatment of RA...