K Lee

Summary

Affiliation: Ewha Womans University
Country: Korea

Publications

  1. ncbi request reprint Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar
    R Dacquin
    Baylor College of Medicine, Department of Molecular and Human Genetics and Bone Disease Program of Texas, Houston, Texas, USA
    Dev Dyn 229:826-34. 2004
  2. pmc Interaction of the alpha subunit of Na,K-ATPase with cofilin
    K Lee
    College of Pharmacy, Center for Cell Signaling Research and Division of Molecular Life Sciences, Ewha Woman s University, Seoul 120 750, Korea
    Biochem J 353:377-85. 2001
  3. ncbi request reprint Identification of the self-interaction of rat TCTP/IgE-dependent histamine-releasing factor using yeast two-hybrid system
    T Yoon
    College of Pharmacy, Center for Cell Signaling Research, Ewha Woman s University, Seoul, Korea
    Arch Biochem Biophys 384:379-82. 2000
  4. doi request reprint Translationally controlled tumor protein induces human breast epithelial cell transformation through the activation of Src
    J Jung
    College of Pharmacy, Center for Cell Signalling and Drug Discovery Research, Ewha Womans University, Seoul, Korea
    Oncogene 30:2264-74. 2011
  5. ncbi request reprint Identification of the calcium binding sites in translationally controlled tumor protein
    M Kim
    College of Pharmacy, Center for Cell Signaling Research and Division of Molecular Life Sciences, Ewha Womans University, Seoul, Korea
    Arch Pharm Res 23:633-6. 2000
  6. ncbi request reprint Nucleotide and deduced amino acid sequences of rat myosin binding protein H (MyBP-H)
    J Jung
    College of Pharmacy, Ewha Womans University, Seoul, Korea
    Arch Pharm Res 21:712-7. 1998
  7. pmc The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response
    W Tirasophon
    Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0650, USA
    Genes Dev 14:2725-36. 2000
  8. ncbi request reprint Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
    Z S Chen
    Medical Science Division, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Biol Chem 276:33747-54. 2001
  9. pmc Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle
    M S Spector
    Program in Molecular Biology, Sloan Kettering Cancer Center, New York, New York 10021, USA
    Mol Cell Biol 17:545-52. 1997
  10. ncbi request reprint Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440
    K E Nelson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Environ Microbiol 4:799-808. 2002

Collaborators

  • C Kim
  • T Yoon
  • Kenji Ueda
  • Jean Luc Thomas
  • E Schipani
  • Randal Kaufman
  • Lu Liu
  • I T Paulsen
  • Soohee Lee
  • C T Miller
  • A K Dixon
  • J Jung
  • R Nicholson
  • Z S Chen
  • M Kim
  • A M S El-Eragi
  • S Kang
  • P J Richardson
  • E B Stevens
  • R D Pinnock
  • J M Schumacher
  • D Spanswick
  • R Dacquin
  • S Edelhoff
  • S Acharjee
  • R E Braun
  • K E Nelson
  • H deSilva
  • K H Song
  • G D Kruh
  • J Y Park
  • S P Yusaf
  • H Y Kim
  • K Sohn
  • P J Cox
  • W Tirasophon
  • C A Holland-Staley
  • S Hsieh
  • K Morgan
  • C Disteche
  • M J Meagher
  • F W Buaas
  • N S Saeed
  • K Kang
  • M E Hamid
  • A H Ahmed
  • K Back
  • M M Mukhtar
  • Y H Kook
  • B Kauppi
  • P E Fields
  • K Kim
  • M A Osley
  • H Vaudry
  • J Verna
  • J Nichols
  • E A Olmsted-Davis
  • M A Razik
  • R S Ahn
  • J Kawaguchi
  • J S Moon
  • P J Mee
  • A Smith
  • J A Gallagher
  • H B Kwon
  • J L Do-Rego
  • D Y Oh
  • J Y Seong
  • M S Spector
  • G Karsenty
  • D G Bai
  • J Small
  • D Kosack
  • M J Skynner
  • S R Gill
  • J Lauber
  • M I Bell
  • A Düsterhöft
  • H Khouri
  • C M Fraser
  • S Heim
  • C Weinel
  • T Utterback
  • M Pop
  • E Holtzapple
  • M Rizzo
  • M Holmes
  • M Beanan
  • W Nelson
  • D Moestl

Detail Information

Publications51

  1. ncbi request reprint Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar
    R Dacquin
    Baylor College of Medicine, Department of Molecular and Human Genetics and Bone Disease Program of Texas, Houston, Texas, USA
    Dev Dyn 229:826-34. 2004
    ..The specificity of Ptprv expression in these cells may be a useful tool to elucidate their role in the transition of skeletal elements from cartilage template to bone...
  2. pmc Interaction of the alpha subunit of Na,K-ATPase with cofilin
    K Lee
    College of Pharmacy, Center for Cell Signaling Research and Division of Molecular Life Sciences, Ewha Woman s University, Seoul 120 750, Korea
    Biochem J 353:377-85. 2001
    ....
  3. ncbi request reprint Identification of the self-interaction of rat TCTP/IgE-dependent histamine-releasing factor using yeast two-hybrid system
    T Yoon
    College of Pharmacy, Center for Cell Signaling Research, Ewha Woman s University, Seoul, Korea
    Arch Biochem Biophys 384:379-82. 2000
    ..Our data suggests that TCTP/HRF may have a potential to self-interact through the C-terminal region, and the self-interaction property may be related to its biological function...
  4. doi request reprint Translationally controlled tumor protein induces human breast epithelial cell transformation through the activation of Src
    J Jung
    College of Pharmacy, Center for Cell Signalling and Drug Discovery Research, Ewha Womans University, Seoul, Korea
    Oncogene 30:2264-74. 2011
    ..These findings suggest that TCTP induces tumorigenesis through distinct multicellular signaling pathways involving Src-dependent EGFR transactivation, ROS generation and MMP expression...
  5. ncbi request reprint Identification of the calcium binding sites in translationally controlled tumor protein
    M Kim
    College of Pharmacy, Center for Cell Signaling Research and Division of Molecular Life Sciences, Ewha Womans University, Seoul, Korea
    Arch Pharm Res 23:633-6. 2000
    ..Thus, our data confirm that TCTP is a novel family of Ca2+ -binding protein...
  6. ncbi request reprint Nucleotide and deduced amino acid sequences of rat myosin binding protein H (MyBP-H)
    J Jung
    College of Pharmacy, Ewha Womans University, Seoul, Korea
    Arch Pharm Res 21:712-7. 1998
    ..Computer analysis of the primary sequence of rat MyBP-H predicted 11 protein kinase C (PKC) phosphorylation site, 7 casein kinase II (CK2) phosphorylation site and 4 N-myristoylation site...
  7. pmc The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response
    W Tirasophon
    Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0650, USA
    Genes Dev 14:2725-36. 2000
    ..Finally, the RNase activity of wild-type IRE1 alpha down-regulates hIre1 alpha mRNA expression by a novel mechanism involving cis-mediated IRE1 alpha-dependent cleavage at three specific sites within the 5' end of Ire1 alpha mRNA...
  8. ncbi request reprint Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
    Z S Chen
    Medical Science Division, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Biol Chem 276:33747-54. 2001
    ....
  9. pmc Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle
    M S Spector
    Program in Molecular Biology, Sloan Kettering Cancer Center, New York, New York 10021, USA
    Mol Cell Biol 17:545-52. 1997
    ..Thus, it represents the first example of a transcriptional corepressor with a direct role in cell cycle-regulated transcription...
  10. ncbi request reprint Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440
    K E Nelson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Environ Microbiol 4:799-808. 2002
    ..Analysis of the genome gives insight into the non-pathogenic nature of P. putida and points to potential new applications in agriculture, biocatalysis, bioremediation and bioplastic production...
  11. pmc Aerobic activity of Escherichia coli alcohol dehydrogenase is determined by a single amino acid
    C A Holland-Staley
    Infectious Disease Research, Henry Ford Hospital, Detroit, Michigan 48202, USA
    J Bacteriol 182:6049-54. 2000
    ..These findings suggest that adhE expression is also regulated posttranslationally and that strict regulation of alcohol dehydrogenase activity in E. coli is physiologically significant...
  12. ncbi request reprint Stage-dependent regulation of ovarian pituitary adenylate cyclase-activating polypeptide mRNA levels by GnRH in cultured rat granulosa cells
    J Y Park
    Hormone Research Center, Chonnam National University, Kwangju 500-757, Republic of Korea
    Endocrinology 142:3828-35. 2001
    ....
  13. ncbi request reprint Characterization of tryptamine 5-hydroxylase and serotonin synthesis in rice plants
    S Kang
    Department of Molecular Biotechnology, College of Agriculture and Life Sciences, Agricultural Plant Stress Research Center, Biotechnology Research Institute, Chonnam National University, Gwangju 500 757, South Korea
    Plant Cell Rep 26:2009-15. 2007
    ..However, no significant increase in serotonin was observed in rice tissues grown in the presence of tryptophan, suggesting that tryptamine is a bottleneck intermediate substrate for serotonin synthesis...
  14. ncbi request reprint Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter
    K Lee
    Division of Medical Sciences, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Cancer Res 58:2741-7. 1998
    ..These data indicate that MOAT-B is a ubiquitously expressed transporter that is closely related to MRP and cMOAT and raise the possibility that it may be an organic anion pump relevant to cellular detoxification...
  15. ncbi request reprint Comparative assays of the rpoB gene for identification of Mycobacterium tuberculosis isolated from patients in Sudan
    A M S El-Eragi
    Central Veterinary Research Laboratories, Soba, Khartoum, Sudan
    Int J Tuberc Lung Dis 11:671-5. 2007
    ..To characterise mycobacterial clinical isolates based on amplification of the rpoB gene...
  16. ncbi request reprint Tissue distribution and functional expression of the human voltage-gated sodium channel beta3 subunit
    E B Stevens
    Parke Davis Neuroscience Research Centre, Cambridge University, UK
    Pflugers Arch 441:481-8. 2001
    ..This is the first study demonstrating that beta3 is expressed in adult mammalian skeletal muscle and can functionally couple to the skeletal muscle alpha subunit, SkM1...
  17. ncbi request reprint Noradrenergic receptor mRNA expression in adult rat superficial dorsal horn and dorsal root ganglion neurons
    R Nicholson
    Department of Biological Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK
    Neurosci Lett 380:316-21. 2005
    ..The present study provides an insight into the modulation of sensory processing at the level of the spinal cord following adrenoceptor activation...
  18. ncbi request reprint Molecular cloning, pharmacological characterization, and histochemical distribution of frog vasotocin and mesotocin receptors
    S Acharjee
    Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 500 757, Korea
    J Mol Endocrinol 33:293-313. 2004
    ....
  19. ncbi request reprint Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function
    Z S Chen
    Department of Cancer Chemotherapy, Institute for Cancer Research, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
    Int J Cancer 93:107-13. 2001
    ..In addition, the capacity of AG-A to reduce cellular glutathione levels may contribute to the modulating activity of MRP1...
  20. ncbi request reprint Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications
    K Lee
    Molecular Recognition Section, LBC, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
    Bioorg Med Chem Lett 11:1333-7. 2001
    ..The 5'-uronamide modification preserved [N6-(3-iodobenzyl)] or enhanced (N6-methyl) affinity at A3ARs, while the 2'-deoxy modification reduced affinity and efficacy in a functional assay...
  21. ncbi request reprint Human mesenchymal stem cells maintain transgene expression during expansion and differentiation
    K Lee
    Osiris Therapeutics, Inc, 2001 Aliceanna Street, Baltimore, Maryland 21231-2001, USA
    Mol Ther 3:857-66. 2001
    ..These results illustrate the ability of hMSCs to express genes of therapeutic potential and demonstrate their potential clinical utility as cellular vehicles for systemic gene delivery...
  22. ncbi request reprint Serotonin receptor mRNA expression in rat dorsal root ganglion neurons
    R Nicholson
    Pfizer Global Research and Development, Cambridge University Forvie Site, Robinson Way, CB2 2QB, Cambridge, UK
    Neurosci Lett 337:119-22. 2003
    ..The present study provides an insight into the molecular profile of 5-HT receptor subtypes in neurons responsible for modulating sensory information...
  23. ncbi request reprint Expression of voltage-gated calcium channel subunits in rat dorsal root ganglion neurons
    S P Yusaf
    Pfizer Global Research and Development, Cambridge University Forvie Site, CB2 2QB, Cambridge, UK
    Neurosci Lett 311:137-41. 2001
    ..The present study provides an insight into the molecular profile of calcium channel alpha(1) and alpha(2)delta subunits in the neurons responsible for transmitting sensory information...
  24. ncbi request reprint G156A MGMT-transduced human mesenchymal stem cells can be selectively enriched by O6-benzylguanine and BCNU
    K Lee
    Department of Medicine, Case Western Reserve University, Ireland Cancer Center of University Hospitals of Cleveland, OH 44106, USA
    J Hematother Stem Cell Res 10:691-701. 2001
    ..G156A-MGMT is a powerful selectable gene for a second marker gene in hMSCs. Drug resistance gene transfer into hMSCs may allow in vivo enrichment of hMSCs when MSC homing and engraftment into target tissues is optimized...
  25. ncbi request reprint LH induces orphan nuclear receptor Nur77 gene expression in testicular Leydig cells
    K H Song
    Hormone Research Center, Chonnam National University, Kwangju 500-757, Republic of Korea
    Endocrinology 142:5116-23. 2001
    ..Taken together, these results demonstrate that LH induces Nur77 gene expression, and Nur77 may play an important role in the LH-mediated steroidogenesis in Leydig cells...
  26. ncbi request reprint Single cell expression analysis--pharmacogenomic potential
    A K Dixon
    Cambridge Biotechnology Ltd, Dept of Pharmacology, Tennis Court Road, UK
    Pharmacogenomics 3:809-22. 2002
    ..A clearer understanding of gene expression differences at such a discrete level provides an opportunity to develop drugs with more targeted pharmacologies or with decreased side effects...
  27. ncbi request reprint Transgenic mice expressing surface markers for IFN-gamma and IL-4 producing cells
    S Hsieh
    Department and Institute of Microbiology and Immunology, National Yang Ming University School of Medicine, 11221, Taipei, Taiwan, ROC
    Mol Immunol 37:281-93. 2000
    ..These surface markers should permit isolation of viable cells according to their T(H) type for adoptive transfer experiments, and may serve as a model system for tracing the development of T(H)1 and T(H)2-type cells in vivo...
  28. ncbi request reprint sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development
    C T Miller
    Institute of Neuroscience, Eugene, OR 97403 1254, USA
    Development 127:3815-28. 2000
    ..Collectively our results support a model for dorsoventral patterning of the gnathostome pharyngeal arches in which Et-1 in the environment of the postmigratory cranial neural crest specifies the lower jaw and other ventral arch fates...
  29. ncbi request reprint Identification of a developmentally regulated protein tyrosine phosphatase in embryonic stem cells that is a marker of pluripotential epiblast and early mesoderm
    K Lee
    Centre for Genome Research, University of Edinburgh, UK
    Mech Dev 59:153-64. 1996
    ..Transcripts are present transiently in newly formed embryonic mesoderm. These data suggest that this transmembrane signaling molecule is associated with developmental lability in early embryogenesis...
  30. ncbi request reprint Activity and autophosphorylation of LAMMER protein kinases
    K Lee
    Waksman Institute, Rutgers University, Piscataway, New Jersey 08855 0759, USA
    J Biol Chem 271:27299-303. 1996
    ....
  31. pmc A testis cytoplasmic RNA-binding protein that has the properties of a translational repressor
    K Lee
    Department of Genetics, University of Washington, Seattle 98195, USA
    Mol Cell Biol 16:3023-34. 1996
    ..While this protein lacks complete specificity for Prm-1-containing RNAs in vitro, the properties of Prbp are consistent with it acting as a general repressor of translation...
  32. ncbi request reprint Differential sensitivity of human and mouse alkyltransferase to O6-benzylguanine using a transgenic model
    L Liu
    Division of Hematology and Oncology, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4937
    Cancer Res 56:1880-5. 1996
    ..This may influence the therapeutic index of O6-bG-BCNU combinations observed in human tumor xenograft-bearing mice...
  33. pmc Mg(2+)-dependent inhibition of KATP by sulphonylureas in CRI-G1 insulin-secreting cells
    K Lee
    Department of Pharmacology, University of Cambridge
    Br J Pharmacol 111:632-40. 1994
    ....
  34. ncbi request reprint Linkage of phosphoribosylpyrophosphate synthetases 1 and 2, Prps1 and Prps2, on the mouse X chromosome
    K Lee
    Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, New York 14263
    Mamm Genome 5:612-5. 1994
    ....
  35. pmc Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules
    J M Schumacher
    Department of Genetics, University of Washington, Seattle 98195, USA
    J Cell Biol 129:1023-32. 1995
    ....
  36. ncbi request reprint Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain
    C T Bond
    Vollum Institute, Oregon Health Sciences University, Portland 97201, USA
    FEBS Lett 367:61-6. 1995
    ..However, pharmacological differences and the lack of ATP-sensitivity, suggest that if, this is the case, heterologous subunits must exert strong modulatory influences on the native channel...
  37. ncbi request reprint Distribution of Tenr, an RNA-binding protein, in a lattice-like network within the spermatid nucleus in the mouse
    J M Schumacher
    Department of Genetics, SK 50, University of Washington, Seattle 98195, USA
    Biol Reprod 52:1274-83. 1995
    ..We suggest that the Tenr protein may be involved in testis-specific nuclear posttranscriptional processes such as heterogeneous nuclear RNA (hnRNA) packaging, alternative splicing, or nuclear/cytoplasmic transport of mRNAs...
  38. ncbi request reprint A tactile sensory system of Myxococcus xanthus involves an extracellular NAD(P)(+)-containing protein
    B U Lee
    Department of Microbiology, University of Georgia, Athens 30602, USA
    Genes Dev 9:2964-73. 1995
    ..Furthermore, a MalE-CsgA protein containing CsgA S135T was not able to restore development to csgA cells. In conclusion, amino acids conserved in the coenzyme binding pocket and catalytic site are essential for C-signaling...
  39. ncbi request reprint Immunocytochemical localization of fodrin and ankyrin in bovine chromaffin cells in vitro
    T Fujimoto
    Department of Anatomy, Faculty of Medicine, Kyoto University, Japan
    J Histochem Cytochem 39:1485-93. 1991
    ..The existence of both proteins in the coated region implies that they are functionally related to exocytosis and/or to ensuing membrane retrieval in the chromaffin cell...
  40. ncbi request reprint Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region
    M A Razik
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Biol Chem 272:28237-46. 1997
    ....
  41. ncbi request reprint Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells
    K Lee
    Upstate Medical University, Pathology Department, Syracuse, New York 13210, USA
    Cancer Res 60:3631-7. 2000
    ..mirk is not mutated in colon carcinomas. Mirk may mediate tumor cell survival in mitogen-poor environments or early in colon cancer development before many autocrine growth factors have been induced...
  42. pmc beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics
    K Morgan
    Departments of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, United Kingdom CB2 1QW
    Proc Natl Acad Sci U S A 97:2308-13. 2000
    ..The expression of beta3 within the central nervous system differs significantly from beta1. Our results strongly suggest that beta3 performs a distinct neurophysiological function...
  43. ncbi request reprint Cloning and characterization of the mouse interleukin enhancer binding factor 3 (Ilf3) homolog in a screen for RNA binding proteins
    F W Buaas
    Department of Genetics, University of Washington, Seattle 98195, USA
    Mamm Genome 10:451-6. 1999
    ....
  44. ncbi request reprint Identification of ZFR, an ancient and highly conserved murine chromosome-associated zinc finger protein
    M J Meagher
    Department of Genetics, University of Washington, Seattle, WA 98195, USA
    Gene 228:197-211. 1999
    ..Using fluorescent in situ hybridization we mapped Zfr to chromosome 15 region A. ZFR appears to be an ancient protein, as apparent homologs exist in invertebrates (D. melanogaster) nematodes (C. elegans) and humans (H. sapiens)...
  45. ncbi request reprint B7.1 is a quantitatively stronger costimulus than B7.2 in the activation of naive CD8+ TCR-transgenic T cells
    P E Fields
    Department of Pathology, University of Chicago, IL 60637, USA
    J Immunol 161:5268-75. 1998
    ..2. Further, our results indicate that the activation state of the responding T cell may influence the efficiency with which the T cell can respond to a costimulatory signal provided by either B7.1 or B7.2...
  46. pmc Isolation and characterization of toluene-sensitive mutants from the toluene-resistant bacterium Pseudomonas putida GM73
    K Kim
    Department of Microbiology, Gyeongsang National University, Gazwadong 900, Chinju 660 701, Korea
    J Bacteriol 180:3692-6. 1998
    ..Characterization of these mutants and identification of mutant genes suggested that active efflux mechanism and efficient repair of damaged membranes were important in toluene resistance...
  47. ncbi request reprint Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase
    B Kauppi
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Structure 6:571-86. 1998
    ..The present study was conducted to provide essential structural information necessary for elucidating the mechanism of action of NDO...
  48. pmc Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor
    H deSilva
    Program in Molecular Biology, Sloan Kettering Cancer Center and Cornell University Graduate School of Medical Sciences, New York, New York 10021, USA
    Genetics 148:657-67. 1998
    ..It was additionally found that the Hir1p WD repeats functionally interacted with the SPT4, SPT5, and SPT6 gene products, suggesting that these repeats may direct Hir1p to different protein complexes...
  49. pmc A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae
    J Verna
    Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 94:13804-9. 1997
    ..The functional characteristics and cellular localization of WSC suggest that they may mediate intracellular responses to environmental stress in yeast...
  50. pmc Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide
    E Schipani
    Endocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 94:13689-94. 1997
    ..These findings suggest that rescued PTHrP-/- mice may gain considerable importance for studying the diverse, possibly tissue-specific role(s) of PTHrP in postnatal development...
  51. ncbi request reprint Identification of ecdysone response elements by analysis of the Drosophila Eip28/29 gene
    L Cherbas
    Institute for Molecular and Cellular Biology, Indiana University, Bloomington 47405
    Genes Dev 5:120-31. 1991
    ..The similarity of the EcRE sequence to response elements for estrogen, thyroid hormone, and retinoic acid receptors suggests that the steroid receptors and their signal transduction mechanisms have been strongly and broadly conserved...