Hwankyu Lee

Summary

Affiliation: Dankook University
Country: Korea

Publications

  1. doi Effect of polyelectrolyte size on multilayer conformation and dynamics at different temperatures and salt concentrations
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea Electronic address
    J Mol Graph Model 70:246-252. 2016
  2. doi Effects of temperature, salt concentration, and the protonation state on the dynamics and hydrogen-bond interactions of polyelectrolyte multilayers on lipid membranes
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 18:6691-700. 2016
  3. doi Effects of imidazolium-based ionic surfactants on the size and dynamics of phosphatidylcholine bilayers with saturated and unsaturated chains
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin 448 701, South Korea Electronic address
    J Mol Graph Model 60:162-8. 2015
  4. doi Effects of imidazolium-based ionic liquids on the stability and dynamics of gramicidin A and lipid bilayers at different salt concentrations
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin 448 701, South Korea Electronic address
    J Mol Graph Model 61:53-60. 2015
  5. doi The binding and insertion of imidazolium-based ionic surfactants into lipid bilayers: the effects of the surfactant size and salt concentration
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 17:5725-33. 2015
  6. doi Dynamics and stability of lipid bilayers modulated by thermosensitive polypeptides, cholesterols, and PEGylated lipids
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 16:3763-70. 2014
  7. doi Effect of the structural difference between Bax-α5 and Bcl-xL-α5 on their interactions with lipid bilayers
    Eol Han
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 16:981-8. 2014
  8. doi Membrane penetration and curvature induced by single-walled carbon nanotubes: the effect of diameter, length, and concentration
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 15:16334-40. 2013
  9. doi Interparticle dispersion, membrane curvature, and penetration induced by single-walled carbon nanotubes wrapped with lipids and PEGylated lipids
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    J Phys Chem B 117:1337-44. 2013
  10. pmc Coarse-grained model for PEGylated lipids: effect of PEGylation on the size and shape of self-assembled structures
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    J Phys Chem B 115:7830-7. 2011

Collaborators

  • Eol Han
  • Sun Young Woo
  • Sun Min Park
  • Hyun Ryoung Kim
  • Minwoo Kim
  • Sang Jun Park
  • Jungyong Nam
  • Eun Sung Park
  • Jae Min Cha
  • Min Sang Kim
  • Ronald G Larson
  • Jae Chan Park
  • Su Young Chae

Detail Information

Publications16

  1. doi Effect of polyelectrolyte size on multilayer conformation and dynamics at different temperatures and salt concentrations
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea Electronic address
    J Mol Graph Model 70:246-252. 2016
    ....
  2. doi Effects of temperature, salt concentration, and the protonation state on the dynamics and hydrogen-bond interactions of polyelectrolyte multilayers on lipid membranes
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 18:6691-700. 2016
    ....
  3. doi Effects of imidazolium-based ionic surfactants on the size and dynamics of phosphatidylcholine bilayers with saturated and unsaturated chains
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin 448 701, South Korea Electronic address
    J Mol Graph Model 60:162-8. 2015
    ....
  4. doi Effects of imidazolium-based ionic liquids on the stability and dynamics of gramicidin A and lipid bilayers at different salt concentrations
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin 448 701, South Korea Electronic address
    J Mol Graph Model 61:53-60. 2015
    ..15M NaCl, ILs do not only stabilize the curved bilayer but also significantly increase the lateral mobility of gA dimers and lipids, which can reduce gA-induced pore formation, leading to the decreased ion permeability. ..
  5. doi The binding and insertion of imidazolium-based ionic surfactants into lipid bilayers: the effects of the surfactant size and salt concentration
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 17:5725-33. 2015
    ....
  6. doi Dynamics and stability of lipid bilayers modulated by thermosensitive polypeptides, cholesterols, and PEGylated lipids
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 16:3763-70. 2014
    ....
  7. doi Effect of the structural difference between Bax-α5 and Bcl-xL-α5 on their interactions with lipid bilayers
    Eol Han
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 16:981-8. 2014
    ..Our findings help explain the experimental observation that showed that Bax-α5 disorders lipids and induces pore formation, but Bcl-xL-α5 does not. ..
  8. doi Membrane penetration and curvature induced by single-walled carbon nanotubes: the effect of diameter, length, and concentration
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Phys Chem Chem Phys 15:16334-40. 2013
    ..These findings imply that the SWNT-induced membrane penetration and curvature are modulated by a combination of SWNT length, diameter, and concentration. ..
  9. doi Interparticle dispersion, membrane curvature, and penetration induced by single-walled carbon nanotubes wrapped with lipids and PEGylated lipids
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    J Phys Chem B 117:1337-44. 2013
    ..Our findings indicate that interparticle aggregation, SWNT penetration, and membrane curvature can be modulated by the SWNT-lipid structure and the PEG length...
  10. pmc Coarse-grained model for PEGylated lipids: effect of PEGylation on the size and shape of self-assembled structures
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    J Phys Chem B 115:7830-7. 2011
    ..The ability of PEGylated lipids to induce the membrane curvature by the bulky headgroup with larger PEG, and thereby modulate the phase behavior and size of lipid assemblies, arises from their relative concentration...
  11. doi Effects of PEGylation on the binding interaction of magainin 2 and tachyplesin I with lipid bilayer surface
    Eol Han
    Department of Chemical Engineering, Dankook University, Yongin 448 701, South Korea
    Langmuir 29:14214-21. 2013
    ..These simulation findings qualitatively support the experimental observation of the different extents of the reduced membrane-permeabilizing activity for PEGylated magainin 2 and tachyplesin I. ..
  12. pmc All-atom simulations and free-energy calculations of coiled-coil peptides with lipid bilayers: binding strength, structural transition, and effect on lipid dynamics
    Sun Young Woo
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Sci Rep 6:22299. 2016
    ..These findings help explain the experimentally observed or proposed differences in the insertion depth, binding strength, and structural transition of E and K peptides, and support the snorkeling effect. ..
  13. doi Adsorption of Plasma Proteins onto PEGylated Lipid Bilayers: The Effect of PEG Size and Grafting Density
    Hwankyu Lee
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    Biomacromolecules 17:1757-65. 2016
    ..This helps explain and clarify experiments that show much less adsorption of plasma proteins onto the particle or membrane surface when PEGs are in the brush rather than in the mushroom state. ..
  14. doi Structural effects of tachyplesin I and its linear derivative on their aggregation and mobility in lipid bilayers
    Eol Han
    Department of Chemical Engineering, Dankook University, Yongin, 448 701, South Korea
    J Mol Graph Model 59:123-8. 2015
    ....
  15. pmc Formulation optimization and in vivo proof-of-concept study of thermosensitive liposomes balanced by phospholipid, elastin-like polypeptide, and cholesterol
    Sun Min Park
    Drug Delivery System Group, Bio Research Center, Samsung Advanced Institute of Technology SAIT, Yongin, Gyeonggi Do, South Korea
    PLoS ONE 9:e103116. 2014
    ..Finally, we identified effective drug accumulation in tumor tissues and antitumor efficacy with our optimized e-TSL, while adjusting lag-times for systemic accumulation. ..
  16. doi Effect of arginine-rich peptide length on the structure and binding strength of siRNA-peptide complexes
    Minwoo Kim
    Bio Research Center, Samsung Advanced Institute of Technology SAIT, Samsung Electronics Co, Ltd, Yongin, 446 712, South Korea
    J Phys Chem B 117:6917-26. 2013
    ..5 peptides per siRNA, the longer 18-residue peptide has a charge ratio of roughly unity and also shows a tight complex, just as the 9-residue peptide does at a 5:1 mole ratio, where its charge ratio is also unity...