Joo Hung Park

Summary

Affiliation: Changwon National University
Country: Korea

Publications

  1. ncbi request reprint Hypertonicity induction of melanoma antigen, a tumor-associated antigen
    Joo Hung Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 13:288-95. 2002
  2. ncbi request reprint Up-regulation of the expression of major histocompatibility complex class I antigens by plasmid DNA transfection in non-hematopoietic cells
    J H Park
    Department of Biology, Changwon National University, Kyungnam, South Korea
    FEBS Lett 436:55-60. 1998
  3. ncbi request reprint Effective immunotherapy of cancer by DNA vaccination
    J H Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 9:384-91. 1999
  4. ncbi request reprint Functional characterization of the rat gamma-glutamyl transpeptidase promoter that is expressed in transformed rat liver epithelial cells
    J H Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 10:361-6. 2000
  5. ncbi request reprint TCDD-up-regulation of IGFBP-6 and IL-5R alpha subunit genes in vivo and in vitro
    J H Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 12:372-9. 2001
  6. ncbi request reprint Up-regulated expression of genes encoding Hrk and IL-3R beta subunit by TCDD in vivo and in vitro
    Joo Hung Park
    Department of Biology, Changwon National University, 9 Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 129:1-11. 2002
  7. ncbi request reprint hMAGE-A1 overexpression reduces TNF-alpha cytotoxicity in ME-180 cells
    Joo Hung Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 14:122-9. 2002
  8. ncbi request reprint TCDD-induced apoptosis in EL-4 cells deficient of the aryl hydrocarbon receptor and down-regulation of IGFBP-6 prevented the apoptotic cell death
    Joo Hung Park
    Department of Biology, Changwon National University, 9, Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 145:55-68. 2003
  9. ncbi request reprint Benzo(a)pyrene inhibits growth and functional differentiation of mouse bone marrow-derived dendritic cells. Downregulation of RelB and eIF3 p170 by benzo(a)pyrene
    Ju Ae Hwang
    Department of Biology, Changwon National University, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 169:82-90. 2007
  10. ncbi request reprint 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates functional differentiation of mouse bone marrow-derived dendritic cells Downregulation of RelB by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Jin Ah Lee
    Department of Biology, Changwon National University, 9 Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 173:31-40. 2007

Collaborators

  • Seung Hun Lee
  • Sung Joo Kim
  • J K Kim
  • C J Kim
  • J H Lee
  • Ju Ae Hwang
  • Kyu Tae Jeong
  • Sung Jun Hwang
  • Dong Min Lee
  • Chun Sik Yoon
  • Hye Rin Kim
  • Chang Hwan Jeon
  • You Jung Hwang
  • Seon Woo Cheong
  • Dah Won Gin
  • Ha Na Sung
  • Byoung Chul Gill
  • Mi Ok Yun
  • Gap Soo Oh
  • Ah Reum Seong
  • Yong Uk Park
  • Hye Lin Kim
  • Hyun Jin Cho
  • Jung Hyo Jin
  • Hyun Joo Youn
  • Alexander J Lazar
  • Raphael E Pollock
  • Heung Mo Yang
  • Sung Yeon Joo
  • Doo Pyo Hong
  • Dina Lev
  • Yoon La Choi
  • Sun Woo Cheong
  • Dah Won Jin
  • Sung Jin Hong
  • Yong Gi Hwang
  • Chang Yeol Yeo
  • Hye Ryun Pak
  • Eun Jin Hahn
  • Min Sun Hong

Detail Information

Publications28

  1. ncbi request reprint Hypertonicity induction of melanoma antigen, a tumor-associated antigen
    Joo Hung Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 13:288-95. 2002
    ..This is the first report that the MAGE expression is regulated by means other than the genome-wide demethylation of CpG dinucleotides...
  2. ncbi request reprint Up-regulation of the expression of major histocompatibility complex class I antigens by plasmid DNA transfection in non-hematopoietic cells
    J H Park
    Department of Biology, Changwon National University, Kyungnam, South Korea
    FEBS Lett 436:55-60. 1998
    ..In contrast, the expression of the MHC class II and beta-actin genes was not affected, suggesting that the up-regulation of MHC class I expression by plasmid DNA works in a gene-specific manner...
  3. ncbi request reprint Effective immunotherapy of cancer by DNA vaccination
    J H Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 9:384-91. 1999
    ..This suggests that intradermal DNA vaccination could provide a novel immunotherapy of cancer...
  4. ncbi request reprint Functional characterization of the rat gamma-glutamyl transpeptidase promoter that is expressed in transformed rat liver epithelial cells
    J H Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 10:361-6. 2000
    ....
  5. ncbi request reprint TCDD-up-regulation of IGFBP-6 and IL-5R alpha subunit genes in vivo and in vitro
    J H Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 12:372-9. 2001
    ..This suggests that IGFBP-6 may be involved in thymic atrophy, and EL4 cells may be used as an in vitro model for studying molecular mechanisms of thymic atrophy...
  6. ncbi request reprint Up-regulated expression of genes encoding Hrk and IL-3R beta subunit by TCDD in vivo and in vitro
    Joo Hung Park
    Department of Biology, Changwon National University, 9 Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 129:1-11. 2002
    ..Finally, Hrk was up-regulated by TCDD in Jurkat T cells, suggesting the potential role of Hrk in thymic atrophy and the possibility of exploiting Jurkat T cells as a suitable in vitro model for studying mechanisms of thymic atrophy...
  7. ncbi request reprint hMAGE-A1 overexpression reduces TNF-alpha cytotoxicity in ME-180 cells
    Joo Hung Park
    Department of Biology, Changwon National University, Korea
    Mol Cells 14:122-9. 2002
    ..These clones displayed a diminished sensitivity to the cytotoxicity that was mediated by TNF, indicating that MAGE-A1 is a protective protein...
  8. ncbi request reprint TCDD-induced apoptosis in EL-4 cells deficient of the aryl hydrocarbon receptor and down-regulation of IGFBP-6 prevented the apoptotic cell death
    Joo Hung Park
    Department of Biology, Changwon National University, 9, Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 145:55-68. 2003
    ..Interestingly, the effects of TCDD were exerted without aromatic hydrocarbon (Ah) receptor (AhR). Taken together, the results have shown that IGFBP-6 mediates the immunotoxic effects of TCDD in EL-4 cells in an AhR-independent pathway...
  9. ncbi request reprint Benzo(a)pyrene inhibits growth and functional differentiation of mouse bone marrow-derived dendritic cells. Downregulation of RelB and eIF3 p170 by benzo(a)pyrene
    Ju Ae Hwang
    Department of Biology, Changwon National University, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 169:82-90. 2007
    ..Expression of RelB, a transcription factor necessary for DC differentiation and function, and eIF3 p170, a subunit of eukaryotic translation initiation factor (eIF)3, was reduced upon BP treatment...
  10. ncbi request reprint 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates functional differentiation of mouse bone marrow-derived dendritic cells Downregulation of RelB by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Jin Ah Lee
    Department of Biology, Changwon National University, 9 Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 173:31-40. 2007
    ..Taken together, although benzo(a)pyrene and TCDD exert their effects via binding to AhR, their effects on the growth and functional differentiation of bone marrow-derived DCs are different...
  11. ncbi request reprint A carbohydrate fraction, AIP1 from Artemisia iwayomogi suppresses pulmonary eosinophilia and Th2-type cytokine production in an ovalbumin-induced allergic asthma. Down-regulation of TNF-alpha expression in the lung
    Jin Ah Lee
    Department of Biology, Changwon National University, Changwon, Kyungnam 641 773, South Korea
    Int Immunopharmacol 8:117-25. 2008
    ....
  12. doi request reprint 2,3,7,8-Tetrachlorodibenzo-p-dioxin up-regulates stathmin 1 in the eye: suggestive evidence for the involvement of stathmin 1 in accelerated eye opening in mice induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Dah Won Gin
    Department of Biology, Changwon National University, 9, Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 196:87-94. 2010
    ....
  13. doi request reprint 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates the expression of cKrox and Runx3, transcription regulatory factors controlling the lineage commitment of CD4+CD8+ into CD4 and CD8 thymocytes, respectively
    Byoung Chul Gill
    Department of Biology, Changwon National University, 9 Sarim dong, Changwon 641 773, Kyungnam, South Korea
    Toxicol Lett 180:189-95. 2008
    ..Our findings could help in understanding the regulatory mechanisms of TCDD on thymocyte development, in particular on the skewed differentiation of DP into CD8 SP thymocytes...
  14. doi request reprint Uremic toxin indoxyl 3-sulfate regulates the differentiation of Th2 but not of Th1 cells to lessen allergic asthma
    You Jung Hwang
    Department of Biology, Changwon National University, Kyungnam, Changwon, 641 773, South Korea
    Toxicol Lett 225:130-8. 2014
    ..Effects of I3S on Th2 differentiation were suppressed by α-naphtoflavone, an AhR antagonist, indicating that I3S regulates Th2 differentiation AhR-dependently...
  15. doi request reprint Chlorogenic acid suppresses pulmonary eosinophilia, IgE production, and Th2-type cytokine production in an ovalbumin-induced allergic asthma: activation of STAT-6 and JNK is inhibited by chlorogenic acid
    Hye Rin Kim
    Department of Biology, Changwon National University, 9, Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Int Immunopharmacol 10:1242-8. 2010
    ..Among the molecules, which were activated by IL-4/LPS, activation of STAT-6 and JNK was inhibited by CGA...
  16. doi request reprint SDS3 interacts with ARNT in an AhR ligand-specific manner regulating expression of cKrox and S100A4 in CD4+CD8+ DPK thymocytes differentiation
    Dong Min Lee
    Department of Biology, Changwon National University, Changwon, Kyungnam 641 773, South Korea
    Environ Toxicol Pharmacol 34:858-68. 2012
    ....
  17. ncbi request reprint The fungicide benomyl inhibits differentiation of neural tissue in the Xenopus embryo and animal cap explants
    Chun Sik Yoon
    Institute of Genetic Engineering, Changwon National University, Changwon, Kyungnam 641 773 Korea
    Environ Toxicol 18:327-37. 2003
    ..This inhibition of neural development may have been caused by the inhibition of the assembly of neural microtubules and by the effect of benomyl on neuronal proliferation and migration...
  18. ncbi request reprint Enhanced expression of plasma glutathione peroxidase in the thymus of mice treated with TCDD and its implication for TCDD-induced thymic atrophy
    Hyun Jin Cho
    Department of Biology, Changwon National University, Changwon 641 773, Korea
    Mol Cells 21:276-83. 2006
    ..pGPx is expressed in various tissues in contact with body fluids, and detoxifies hydrogen peroxides and lipid hydroperoxides. It will be of interest to assess the role of pGPx in TCDD-induced thymic atrophy...
  19. doi request reprint FICZ, a tryptophan photoproduct, suppresses pulmonary eosinophilia and Th2-type cytokine production in a mouse model of ovalbumin-induced allergic asthma
    Kyu Tae Jeong
    Department of Biology, Changwon National University, Changwon, Kyungnam 641 773, Korea
    Int Immunopharmacol 13:377-85. 2012
    ..FICZ inhibited both Th2 differentiation and the expression of GATA-3. Finally, activation of STAT6, which is necessary for Th2 differentiation, was inhibited by FICZ...
  20. doi request reprint AIP1, a carbohydrate fraction from Artemisia iwayomogi, modulates the functional differentiation of bone marrow-derived dendritic cells
    Jin Ah Lee
    Department of Biology, Changwon National University, 9, Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Int Immunopharmacol 8:534-41. 2008
    ....
  21. doi request reprint Indoxyl 3-sulfate stimulates Th17 differentiation enhancing phosphorylation of c-Src and STAT3 to worsen experimental autoimmune encephalomyelitis
    Sung Jun Hwang
    Department of Biology, Changwon National University, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 220:109-17. 2013
    ..Finally, we found that I3S worsened experimental autoimmune encephalomyelitis (EAE), which is primarily mediated by Th17 cells, enhancing the frequency of IL-17-producing cells in draining lymph nodes...
  22. doi request reprint Enhancement of ovalbumin-induced pulmonary eosinophilia by intranasal administration of alpha1-proteinase inhibitor type 2 antisense oligonucleotides
    Ha Na Sung
    Department of Biology, Changwon National University, Changwon, Kyungnam, South Korea
    Immunol Lett 122:76-83. 2009
    ....
  23. doi request reprint Toxic effects of carbendazim and n-butyl isocyanate, metabolites of the fungicide benomyl, on early development in the African clawed frog, Xenopus laevis
    Chun Sik Yoon
    Department of Biology, College of Natural Sciences, Changwon National University, Changwon, Kyungnam, Korea
    Environ Toxicol 23:131-44. 2008
    ....
  24. doi request reprint Numerical variations and spontaneous malformations in the early embryos of the Korean salamander, Hynobius leechii, in the farmlands of Korea
    Yong Uk Park
    Department of Biology, College of Natural Sciences, Changwon National University, Changwon, Gyeongnam 641 773, Korea
    Environ Toxicol 25:533-44. 2010
    ..These results indicate that various agricultural chemicals and other unknown factors may cause the aforementioned forms of spontaneous malformations in the embryos of Hynobius leechii...
  25. doi request reprint Induction of S100A4, S100A6, and galectin-1 during the lineage commitment of CD4+CD8+ thymocyte cell line is suppressed by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Chang Hwan Jeon
    Department of Biology, Changwon National University, 9 Sarim dong, Changwon, Kyungnam 641 773, South Korea
    Toxicol Lett 187:157-63. 2009
    ....
  26. ncbi request reprint Identification, expression, and nuclear location of murine Mage-b2 protein, a tumor-associated antigen
    J H Lee
    Department of Biology, Changwon National University, Korea
    Mol Cells 10:647-53. 2000
    ..Immunohistochemistry showed that Mage-b2 is located in the nucleus of Mage-b2 mRNA-positive sarcoma cells. These results should contribute to understanding the biological functions of Mage...
  27. doi request reprint AhR activation by 6-formylindolo[3,2-b]carbazole and 2,3,7,8-tetrachlorodibenzo-p-dioxin inhibit the development of mouse intestinal epithelial cells
    Joo Hung Park
    Department of Biology, Changwon National University, Changwon, Kyungnam, 641 773, Korea Electronic address
    Environ Toxicol Pharmacol 43:44-53. 2016
    ..FICZ inhibited Wnt signaling lowering the level of β-catenin protein. Gene expression analyses demonstrated that FICZ increased expression of Lgr5, Math1, BMP4, and Indian Hedgehog while inhibiting that of Lgr4. ..
  28. pmc Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma
    Ju Ae Hwang
    Transplantation Research Center, Samsung Biomedical Research Institute, Seoul, Republic of Korea Department of Biology, Changwon National University, Changwon, Kyungnam, Republic of Korea
    Oncotarget 5:9065-78. 2014
    ..This study identifies gankyrin, for the first time, as new potential predictive and oncogenic factor of WDLPS and DDLPS, suggesting the potential for service as a future LPS therapeutic approach. ..