Hee Jeong Kong

Summary

Publications

  1. ncbi request reprint Molecular cloning and characterization of LPS-binding protein/bactericidal permeability-increasing protein (LBP/BPI) from olive flounder, Paralichthys olivaceus
    Bo Hye Nam
    Biotechnology Research Division, Aquaculture Industry Department, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 902, Republic of Korea
    Vet Immunol Immunopathol 133:256-63. 2010
  2. ncbi request reprint Molecular and functional characterizations of a Kunitz-type serine protease inhibitor FcKuSPI of the shrimp Fenneropenaeus chinensis
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 216 Gijanghaean ro, Gijang eup, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 35:1025-9. 2013
  3. pmc Molecular and functional analyses of the fast skeletal myosin light chain2 gene of the Korean oily bitterling, Acheilognathus koreensis
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, Busan 619 705, Korea
    Int J Mol Sci 14:16672-84. 2013
  4. ncbi request reprint PoCRIP1, Paralichthys olivaceus cysteine-rich intestinal protein 1: molecular characterization, expression analysis upon Edwardsiella tarda challenge and a possible role in the immune regulation
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 30:917-22. 2011
  5. ncbi request reprint Characterization of the flounder IL-6 promoter and its regulation by the p65 NF-kappaB subunit
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute NFRDI, 408 1 Sirang ri, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 28:961-4. 2010
  6. ncbi request reprint Molecular characterization of the autophagy-related gene Beclin-1 from the olive flounder (Paralichthys olivaceus)
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 31:189-95. 2011
  7. ncbi request reprint Molecular cloning and mRNA expression of the liver-specific cathepsin L1 gene of the olive flounder, Paralichthys olivaceus
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute, Gijang, Busan, Republic of Korea
    Biosci Biotechnol Biochem 75:1214-8. 2011
  8. ncbi request reprint Molecular characterization and transcriptional analysis of the olive flounder (Paralichthys olivaceus) YGHL1 gene in response to hypoxia and infection
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1, Sirang ri, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    Mol Cell Biochem 357:305-12. 2011
  9. ncbi request reprint Genetic organization of two types of flounder warm-temperature acclimation-associated 65-kDa protein and their gene expression profiles
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute
    Biosci Biotechnol Biochem 77:2065-72. 2013
  10. ncbi request reprint Molecular cloning of Kazal-type proteinase inhibitor of the shrimp Fenneropenaeus chinensis
    Hee Jeong Kong
    Biotechnology Research Institute, National Fisheries Research and Development Institute, Gijang gun, Busan, South Korea
    Fish Shellfish Immunol 26:109-14. 2009

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Molecular cloning and characterization of LPS-binding protein/bactericidal permeability-increasing protein (LBP/BPI) from olive flounder, Paralichthys olivaceus
    Bo Hye Nam
    Biotechnology Research Division, Aquaculture Industry Department, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 902, Republic of Korea
    Vet Immunol Immunopathol 133:256-63. 2010
    ..This expression pattern profile corresponded to that of acute inflammatory cytokines, suggesting that it plays a role in the innate immune response, in particular, the acute phase response...
  2. ncbi request reprint Molecular and functional characterizations of a Kunitz-type serine protease inhibitor FcKuSPI of the shrimp Fenneropenaeus chinensis
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 216 Gijanghaean ro, Gijang eup, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 35:1025-9. 2013
    ..Recombinant FcKuSPI protein demonstrated anti-protease activity against trypsin and anticoagulant activity against citrated human plasma in a dose-dependent manner in in vitro assays...
  3. pmc Molecular and functional analyses of the fast skeletal myosin light chain2 gene of the Korean oily bitterling, Acheilognathus koreensis
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, Busan 619 705, Korea
    Int J Mol Sci 14:16672-84. 2013
    ..Although the detailed mechanism underlying the expression of Akmlc2f remains unknown, these results suggest the muscle-specific expression of Akmlc2f transcript and the functional activation of Akmlc2f promoter by C/EBPβ. ..
  4. ncbi request reprint PoCRIP1, Paralichthys olivaceus cysteine-rich intestinal protein 1: molecular characterization, expression analysis upon Edwardsiella tarda challenge and a possible role in the immune regulation
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 30:917-22. 2011
    ..Over-expression of PoCRIP1 augmented p65-driven flounder IL-6 promoter activity in HINAE cells. These results suggest that PoCRIP1 may function in the immune response of the flounder through the regulation of cytokine expression...
  5. ncbi request reprint Characterization of the flounder IL-6 promoter and its regulation by the p65 NF-kappaB subunit
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute NFRDI, 408 1 Sirang ri, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 28:961-4. 2010
    ..These results give us new insight into the regulation of flounder IL-6 transcription by the p65 NF-kappaB subunit...
  6. ncbi request reprint Molecular characterization of the autophagy-related gene Beclin-1 from the olive flounder (Paralichthys olivaceus)
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 31:189-95. 2011
    ..Taken together, these results suggest that PoBeclin-1 may play a role in the innate immune response to viral infection in the flounder...
  7. ncbi request reprint Molecular cloning and mRNA expression of the liver-specific cathepsin L1 gene of the olive flounder, Paralichthys olivaceus
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute, Gijang, Busan, Republic of Korea
    Biosci Biotechnol Biochem 75:1214-8. 2011
    ..RT-PCR analysis revealed that cathepsin L1 transcripts were expressed only in the liver. They were detected from 28 d post-hatching. Under starvation conditions, cathepsin L1 expression was decreased at 30 d...
  8. ncbi request reprint Molecular characterization and transcriptional analysis of the olive flounder (Paralichthys olivaceus) YGHL1 gene in response to hypoxia and infection
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1, Sirang ri, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    Mol Cell Biochem 357:305-12. 2011
    ..Taken together, these results suggest that fYGHL1 is a hypoxia-related gene with potential roles in the hypoxia response mechanism as well as in defense, immune responses, growth, and regulation of reproduction...
  9. ncbi request reprint Genetic organization of two types of flounder warm-temperature acclimation-associated 65-kDa protein and their gene expression profiles
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute
    Biosci Biotechnol Biochem 77:2065-72. 2013
    ..Pathogen challenge induced PoWap65-2 expression in the liver whereas PoWap65-1 was downregulated. Hypoxia induced the expression of both PoWap65s in the liver of juvenile fish. ..
  10. ncbi request reprint Molecular cloning of Kazal-type proteinase inhibitor of the shrimp Fenneropenaeus chinensis
    Hee Jeong Kong
    Biotechnology Research Institute, National Fisheries Research and Development Institute, Gijang gun, Busan, South Korea
    Fish Shellfish Immunol 26:109-14. 2009
    ....
  11. ncbi request reprint Molecular characterization of a tandem-repeat galectin-9 (RuGlec9) from Korean rose bitterling (Rhodeus uyekii)
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, Gijang gun, Busan, Republic of Korea
    Fish Shellfish Immunol 32:939-44. 2012
    ..RuGlec9 mRNA expression in the spleen was increased by lipopolysaccharide. These results suggest that RuGlec9 plays a role in innate immunity in Korean rose bitterling...
  12. ncbi request reprint Gene cloning and characterization of a cold-adapted esterase from Acinetobacter venetianus V28
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute, Busan, Korea
    J Microbiol Biotechnol 22:1245-52. 2012
    ..This cold-adapted esterase will be applicable as catalysts for reaction in the presence of organic solvents and detergents...
  13. ncbi request reprint Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus)
    Bo Hye Nam
    Biotechnology Research Division, National Fisheries Research and Development Institute, Gijang eup, Gijang gun, Busan, Republic of Korea
    Comp Biochem Physiol B Biochem Mol Biol 164:18-28. 2013
    ..These results suggest that the expression ratio of PRP and PACAP is regulated at the transcriptional level depending on the tissues and conditions, and that the unique biological roles of PRP and PACAP differ from that of mammalian PRP...
  14. ncbi request reprint Cloning and expression analysis of cathepsin D in the olive flounder Paralichthys olivaceus
    Eun Mi Park
    Biotechnology Research Institute, National Fisheries Research and Development Institute, Busan, Republic of Korea
    Biosci Biotechnol Biochem 73:1856-9. 2009
    ..The accumulation of cathepsin D mRNA after bacterial infection, as determined by RT-PCR, was constitutive and increased greatly after bacterial infection...
  15. ncbi request reprint Identification of two differentially expressed forms of progranulin mRNA in the teleost fish Paralichthys olivaceus
    Bo Hye Nam
    Biotechnology Research Institute, National Fisheries Research and Development Institute, Gijang gun, Busan, Republic of Korea
    Fish Shellfish Immunol 26:177-82. 2009
    ..These results suggest that type I and type II f-pgrn mRNA are translated into different proteins with different activities in the immune system of flounder...
  16. ncbi request reprint Cloning and characterization of hypusine-containing protein eIF5A from the olive flounder Paralichthys olivaceus
    Hee Jeong Kong
    Biotechnology Research Institute, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    Comp Biochem Physiol B Biochem Mol Biol 153:281-7. 2009
    ....
  17. ncbi request reprint Molecular and functional analyses of growth hormone-releasing hormone (GHRH) from olive flounder (Paralichthys olivaceus)
    Bo Hye Nam
    Biotechnology Research Division, National Fisheries Research and Development Institute, Gijang eup, Gijang gun, Republic of Korea
    Comp Biochem Physiol B Biochem Mol Biol 159:84-91. 2011
    ..These results suggest that the flounder GHRH plays roles in the bidirectional communication network between growth and immunity in fish...
  18. ncbi request reprint Identification and molecular characterization of two hepcidin genes from black rockfish (Sebastes schlegelii)
    Young Ok Kim
    National Fisheries Research and Development Institute, Biotechnology Research Institute, 408 1 Sirang ri, Gijang up, Gijang gun, Busan, Republic of Korea
    Mol Cell Biochem 315:131-6. 2008
    ..Hepcidin I and II dramatically increased at 24 h post-injection, then gradually declined at 3 days in hepcidin II, while hepcidin I expression continued at 3 days after challenge...
  19. ncbi request reprint Cloning and expression analysis of a small HSP26 gene of Pacific abalone (Haliotis discus hannai)
    Eun Mi Park
    Biotechnology Research Institute, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 902, Republic of Korea
    J Environ Biol 29:577-80. 2008
    ..The abalone sHSP26 transcript was induced by heat shock treatment, but not by cold shock treatment...
  20. ncbi request reprint Molecular characterization of tripartite motif protein 25 (TRIM25) involved in ERα-mediated transcription in the Korean rose bitterling Rhodeus uyekii
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, Busan 619 705, Republic of Korea
    Comp Biochem Physiol B Biochem Mol Biol 163:147-53. 2012
    ..Together, these results suggest that the RuTRIM25 regulates the ER-mediated transcription in fish similarly to its mammalian counterpart...
  21. ncbi request reprint An immune responsive complement factor D/adipsin and kallikrein-like serine protease (PoDAK) from the olive flounder Paralichthys olivaceus
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 27:486-92. 2009
    ..In situ hybridization confirmed that PoDAK mRNA is localized in the kidney and heart of individuals infected with VHSV. Further investigations are needed to clarify the function of PoDAK in vivo and in vitro...
  22. ncbi request reprint Hypoxia induces the PDZ domain-containing syntenin in the marine teleost Paralichthys olivaceus
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    Comp Biochem Physiol C Toxicol Pharmacol 152:195-201. 2010
    ..Taken together, these results suggest that PoSyntenin is a hypoxia target gene that has a potential role in the hypoxia response mechanism of fish...
  23. ncbi request reprint Maximal transcriptional activation of piscine soluble Toll-like receptor 5 by the NF-κB subunit p65 and flagellin
    Ji Young Moon
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 902, Republic of Korea
    Fish Shellfish Immunol 31:881-6. 2011
    ..These results suggest that NF-κB and flagellin are essential components that act as a transcription factor and ligand, respectively, for maximal induction of the TLR5S promoter...
  24. ncbi request reprint Cloning and functional characterization of the p65 subunit of NF-κB from olive flounder (Paralichthys olivaceus)
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 705, Republic of Korea
    Fish Shellfish Immunol 30:406-11. 2011
    ..Together, these results suggest that Po-p65 is evolutionarily and functionally conserved in flounder and mammals and may provide clues to the detailed molecular mechanism(s) underlying immune response regulation in flounder...
  25. pmc Genome sequence of Acinetobacter sp. strain P8-3-8, isolated from Fistularia commersonii in Vietnam
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute, 152 1 Haeanro, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    J Bacteriol 193:4288-9. 2011
    ..P8-3-8 (3,905,565 bp, with a G+C content of 37.6%) containing 3,621 putative coding sequences. The genome data reveal a high density of genes encoding transcriptional regulators involved in anaerobic respiration...
  26. ncbi request reprint A C-type lectin like-domain (CTLD)-containing protein (PtLP) from the swimming crab Portunus trituberculatus
    Hee Jeong Kong
    Biotechnology Research Institute, National Fisheries Research and Development Institute, Gijang up, Gijang gun, Busan, South Korea
    Fish Shellfish Immunol 25:311-4. 2008
    ..Quantitative RT-PCR analysis showed that the PtLP mRNA was expressed highly in hepatopancreas and moderately in gills, hemocytes, and ovary of normal swimming crabs...
  27. doi request reprint Development of 52 new polymorphic microsatellite markers for the olive flounder, Paralichthys olivaceus
    Woo Jin Kim
    Biotechnology Research Institute, National Fisheries Research and Development Institute, Busan 619 705, South Korea Genetics and Breeding Research Center, National Fisheries Research and Development Institute, Geoje 656 842, South Korea Department of Microbiology, Pukyung National University, Busan 608 737, South Korea Department of Molecular Biology, Pusan National University, Busan 609 735, South Korea
    Mol Ecol Resour 9:839-42. 2009
    ..0. Segregation analysis within a mapping family revealed non-amplifying null alleles at six loci. These results indicate that these new microsatellite markers will be useful for population genetic, parentage, and genome mapping studies...
  28. ncbi request reprint Roseovarius halocynthiae sp. nov., isolated from the sea squirt Halocynthia roretzi
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute NFRDI, Gijang, Busan 619 705, Republic of Korea
    Int J Syst Evol Microbiol 62:931-6. 2012
    ..nov. is proposed; the type strain is MA1-10T (=KCTC 23462T=CCUG 60745T)...
  29. ncbi request reprint Molecular characterization and expression analysis of a peroxiredoxin 1 cDNA from Korean rose bitterling (Rhodeus uyekii)
    Hyun Kook Cho
    Biotechnology Research Division, National Fisheries Research and Development Institute, 216 Gijanghaean ro, Gijang eup, Gijang gun, Busan, 619 705, Republic of Korea
    Mol Biol Rep 41:2363-70. 2014
    ..These results suggest that RuPrx 1 is conserved through evolution and may play roles similar to its mammalian counterparts...
  30. ncbi request reprint Cloning, characterization and expression analysis of the gene for a putative lipopolysaccharide-induced TNF-alpha factor of the Pacific oyster, Crassostrea gigas
    Eun Mi Park
    National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Busan 619 902, South Korea
    Fish Shellfish Immunol 24:11-7. 2008
    ..This expression pattern suggests that Cg-LITAF is a potent factor in the regulation of genes that are involved in innate defence mechanisms...
  31. ncbi request reprint Identification and characterization of the prepro-vasoactive intestinal peptide gene from the teleost Paralichthys olivaceus
    Bo Hye Nam
    Biotechnology Research Institute, National Fisheries Research and Development Institute, 408 1, Sirang ri, Gijang eup, Gijang gun, Busan 619 902, South Korea
    Vet Immunol Immunopathol 127:249-58. 2009
    ....
  32. ncbi request reprint Antimicrobial activity of peptides derived from olive flounder lipopolysaccharide binding protein/bactericidal permeability-increasing protein (LBP/BPI)
    Bo Hye Nam
    Biotechnology Research Division, National Fisheries Research and Development Institute, Haean ro 216, Gijang eup, Gijang gun, Busan 619 705, Korea
    Mar Drugs 12:5240-57. 2014
    ..These results suggested that the ofLBP-derived peptide bactericidal mechanism may be related to the interaction with intracellular components such as DNA or polymerase. ..
  33. ncbi request reprint N-terminal pI determines the solubility of a recombinant protein lacking an internal transmembrane-like domain in E. coli
    Sang Jun Lee
    Biotechnology Research Division, National Fisheries Research and Development Institute, Pusan 619 902, Korea
    Mol Cells 30:127-35. 2010
    ....
  34. ncbi request reprint A cDNA microarray analysis to identify genes involved in the acute-phase response pathway of the olive flounder after infection with Edwardsiella tarda
    Ji Young Moon
    Biotechnology Research Division, National Fisheries Research and Development Institute, 408 Sirang ri, Gijang eup, Gijang gun, Busan 619 902, Republic of Korea
    Vet Immunol Immunopathol 161:49-56. 2014
    ..tarda infection. These results suggest that the APR mechanism of fish may be regulated differently from that of mammals. The data described here contribute toward our collective understanding of APR, especially in fish. ..
  35. pmc Novel GFP expression using a short N-terminal polypeptide through the defined twin-arginine translocation (Tat) pathway
    Sang Jun Lee
    Biotechnology Research Division, National Fisheries Research and Development Institute, Busan 619 902, Korea
    Mol Cells 32:349-58. 2011
    ..These results show that the short N-terminal polypeptide could substitute for the Tat signal sequence with improved efficiency...
  36. ncbi request reprint Multiple beta-defensin isoforms identified in early developmental stages of the teleost Paralichthys olivaceus
    Bo Hye Nam
    Biotechnology Research Division, Aquaculture Industry Department, National Fisheries Research and Development Institute, 408 1 Sirang ri, Gijang eup, Gijang gun, Busan 619 902, Republic of Korea
    Fish Shellfish Immunol 28:267-74. 2010
    ..We also produced a recombinant fBDI peptide (smfBD) using the expression plasmid pET32 and examined its bioactivity toward Escherichia coli...
  37. ncbi request reprint Characterization, expression profile, and promoter analysis of the Rhodeus uyekii vitellogenin Ao1 gene
    Hee Jeong Kong
    Biotechnology Research Division, National Fisheries Research and Development Institute, Busan 619 705, Korea
    Int J Mol Sci 15:18804-18. 2014
    ..These results suggest that R. uyekii and the Ru-Vg gene may be useful as biomarkers for exposure to E2 or EE2. ..
  38. pmc Draft genome sequence of Kocuria rhizophila P7-4
    Woo Jin Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute, 152 1 Haeanro, Gijang up, Gijang gun, Busan 619 705, Republic of Korea
    J Bacteriol 193:4286-7. 2011
    ..The 2.83-Mb genome sequence consists of 75 large contigs (>100 bp in size) and contains 2,462 predicted protein-coding genes...
  39. ncbi request reprint Paracoccus fistulariae sp. nov., a lipolytic bacterium isolated from bluespotted cornetfish, Fistularia commersonii
    Young Ok Kim
    Biotechnology Research Division, National Fisheries Research and Development Institute, Gijang, Busan 619 705, Republic of Korea
    Int J Syst Evol Microbiol 60:2908-12. 2010
    ..nov. is proposed. The type strain is 22-5(T) (=KCTC 22803(T) =CCUG 58401(T))...