Antonia Kolokythas

Summary

Publications

  1. doi request reprint Renal Cell Carcinoma: Delayed Metachronous Metastases to Parotid and Cerebellum
    Antonia Kolokythas
    Associate Professor, Program Director, Director of Research, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL Electronic address
    J Oral Maxillofac Surg 73:1296-303. 2015
  2. doi request reprint Salivary Biomarkers Associated With Bone Deterioration in Patients With Medication-Related Osteonecrosis of the Jaws
    Antonia Kolokythas
    Associate Professor, Program Director, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, College of Dentistry and the University of Illinois Hospitals and Health Science Center, Chicago, IL Electronic address
    J Oral Maxillofac Surg 73:1741-7. 2015
  3. doi request reprint Does cytokine profiling of aspirate from jaw cysts and tumors have a role in diagnosis?
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Oral Maxillofac Surg 70:1070-80. 2012
  4. ncbi request reprint A non-lip-splitting double mandibular osteotomy technique applied for resection of tumors in the parapharyngeal and pterygomandibular spaces
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, University of Maryland, Baltimore, MD 21201 1754, USA
    J Oral Maxillofac Surg 65:566-9. 2007
  5. ncbi request reprint Odontogenic keratocyst: to decompress or not to decompress? A comparative study of decompression and enucleation versus resection/peripheral ostectomy
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, University of Maryland, Baltimore, MD 21201 1754, USA
    J Oral Maxillofac Surg 65:640-4. 2007
  6. pmc MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma
    Xiqiang Liu
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA
    FEBS Lett 584:4115-20. 2010
  7. doi request reprint Does decompression of odontogenic cysts and cystlike lesions change the histologic diagnosis?
    Thomas Schlieve
    Clinical Assistant Professor, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL
    J Oral Maxillofac Surg 72:1094-105. 2014
  8. pmc Polycomb group protein EZH2-mediated E-cadherin repression promotes metastasis of oral tongue squamous cell carcinoma
    Cheng Wang
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Mol Carcinog 52:229-36. 2013
  9. pmc Identification and experimental validation of G protein alpha inhibiting activity polypeptide 2 (GNAI2) as a microRNA-138 target in tongue squamous cell carcinoma
    Lu Jiang
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, 801 S Paulina Street, Room 530C, Chicago, IL 60612, USA
    Hum Genet 129:189-97. 2011
  10. pmc MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells
    Lu Jiang
    Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, 60612, USA
    Biochem J 432:199-205. 2010

Collaborators

Detail Information

Publications37

  1. doi request reprint Renal Cell Carcinoma: Delayed Metachronous Metastases to Parotid and Cerebellum
    Antonia Kolokythas
    Associate Professor, Program Director, Director of Research, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL Electronic address
    J Oral Maxillofac Surg 73:1296-303. 2015
    ..The metastases occurred more than a decade after treatment of the primary tumor without any other systemic involvement. In addition, the potential differential diagnosis of the parotid mass based on presentation and imaging is discussed...
  2. doi request reprint Salivary Biomarkers Associated With Bone Deterioration in Patients With Medication-Related Osteonecrosis of the Jaws
    Antonia Kolokythas
    Associate Professor, Program Director, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, College of Dentistry and the University of Illinois Hospitals and Health Science Center, Chicago, IL Electronic address
    J Oral Maxillofac Surg 73:1741-7. 2015
    ..They further hypothesized that there would be a difference between these biomarkers in the saliva of patients with medication-relation osteonecrosis of the jaws (MRONJ) and those who have no risk factors for the development of MRONJ...
  3. doi request reprint Does cytokine profiling of aspirate from jaw cysts and tumors have a role in diagnosis?
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Oral Maxillofac Surg 70:1070-80. 2012
    ..The objective of the present study was twofold: first, to assess aspirates for use in cytokine profiling and second, to initiate pilot analyses to determine whether the cytokine profiling can serve as an aid in the diagnosis of jaw lesions...
  4. ncbi request reprint A non-lip-splitting double mandibular osteotomy technique applied for resection of tumors in the parapharyngeal and pterygomandibular spaces
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, University of Maryland, Baltimore, MD 21201 1754, USA
    J Oral Maxillofac Surg 65:566-9. 2007
  5. ncbi request reprint Odontogenic keratocyst: to decompress or not to decompress? A comparative study of decompression and enucleation versus resection/peripheral ostectomy
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, University of Maryland, Baltimore, MD 21201 1754, USA
    J Oral Maxillofac Surg 65:640-4. 2007
    ....
  6. pmc MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma
    Xiqiang Liu
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA
    FEBS Lett 584:4115-20. 2010
    ..Furthermore, the miR-24-mediated change in DND1 expression suppressed the expression of cyclin-dependent kinase inhibitor 1B (CDKN1B), and also led to enhanced proliferation and reduced apoptosis in TSCC cells...
  7. doi request reprint Does decompression of odontogenic cysts and cystlike lesions change the histologic diagnosis?
    Thomas Schlieve
    Clinical Assistant Professor, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL
    J Oral Maxillofac Surg 72:1094-105. 2014
    ..definitive treatment of odontogenic cystlike lesions and determine whether the diagnosis was consistent with the pretreatment diagnosis, thereby answering the clinical question: does decompression change the histologic diagnosis?..
  8. pmc Polycomb group protein EZH2-mediated E-cadherin repression promotes metastasis of oral tongue squamous cell carcinoma
    Cheng Wang
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Mol Carcinog 52:229-36. 2013
    ..Taken together, these data suggest that EZH2 plays major roles in the progression of OTSCC, and may serve as a biomarker or therapeutic target for patients at risk of metastasis...
  9. pmc Identification and experimental validation of G protein alpha inhibiting activity polypeptide 2 (GNAI2) as a microRNA-138 target in tongue squamous cell carcinoma
    Lu Jiang
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, 801 S Paulina Street, Room 530C, Chicago, IL 60612, USA
    Hum Genet 129:189-97. 2011
    ..In summary, we identified a number of high-confident miR-138 target genes, including proto-oncogene GNAI2, which may play an important role in TSCC initiation and progression...
  10. pmc MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells
    Lu Jiang
    Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, 60612, USA
    Biochem J 432:199-205. 2010
    ..Our results indicate that miR-7 plays an important role in TSCC and may serve as a novel therapeutic target for TSCC patients...
  11. pmc MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines
    Xiqiang Liu
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA
    Biochem J 440:23-31. 2011
    ....
  12. doi request reprint Does a difference exist in inferior alveolar canal displacement caused by commonly encountered pathologic entities? An observational study
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL 60612 7210, USA
    J Oral Maxillofac Surg 69:1944-51. 2011
    ..This information would assist the surgical team in treatment planning, diagnostic biopsy, and resection, especially in cases of intraosseous vascular pathologic findings...
  13. pmc Deregulation of manganese superoxide dismutase (SOD2) expression and lymph node metastasis in tongue squamous cell carcinoma
    Xiqiang Liu
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, IL, USA
    BMC Cancer 10:365. 2010
    ..The purpose of this study is to further evaluate whether the expression level of SOD2 is correlated with the metastatic status in TSCC patients...
  14. pmc A prototype tobacco-associated oral squamous cell carcinoma classifier using RNA from brush cytology
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA
    J Oral Pathol Med 42:663-9. 2013
    ..We sought to determine whether the identified mRNAs could be used as markers by a non-invasive detection system for OSCC using RNA from brush cytology...
  15. pmc Effect of postradiotherapy neck dissection on nonregional disease sites
    Mark C Ranck
    Department of Radiation and Cellular Oncology, University of Chicago Medical Center, Chicago, Illinois2Department of Radiation Oncology, University of Illinois at Chicago Medical Center, Chicago
    JAMA Otolaryngol Head Neck Surg 140:12-21. 2014
    ..Because several groups have reported that lymph node involvement also predicts failure at both the primary and distant sites, the extent to which PRND affects nonregional sites of disease remains unclear...
  16. pmc microRNA from brush biopsy to characterize oral squamous cell carcinoma epithelium
    Yalu Zhou
    Department of Oral Medicine and Oral Diagnostics, Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, 801 South Paulina Street, Chicago, Illinois, 60610
    Cancer Med . 2016
    ..This highlights the utility of brush biopsy of oral mucosa to allow simple acquisition of cancer relevant miRNA information from tumor epithelium...
  17. doi request reprint A Loss of Profilin-1 in Late Stage Oral Squamous Cell Carcinoma
    Guy R Adami
    Department of Oral Medicine and Diagnostics, Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, Chicago, IL
    J Oral Pathol Med . 2016
    ..The genes for PFN1 and TMSB4 are both highly expressed in oral tissue and both encode actin monomer binding proteins thought to play a role in cell motility and possibly other crucial parts of tumor progression...
  18. doi request reprint Gene expression based evidence of innate immune response activation in the epithelium with oral lichen planus
    Guy R Adami
    Department of Oral Medicine and Oral Diagnostics, Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, 801 South Paulina Street, Chicago, IL 60612, USA Electronic address
    Arch Oral Biol 59:354-61. 2014
    ..We performed gene expression analysis of the oral epithelium of lesions in subjects with OLP and its sister disease, oral lichenoid reaction (OLR), in order to better understand the role of the keratinocytes in these diseases...
  19. doi request reprint Nerve growth factor and tyrosine kinase A receptor in oral squamous cell carcinoma: is there an association with perineural invasion?
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago College of Dentistry, Chicago, IL, USA
    J Oral Maxillofac Surg 68:1290-5. 2010
    ..We investigated the hypothesis that NGF and its high-affinity receptor tyrosine kinase A (TrkA) are highly expressed in cases of oral SCC that have histologic evidence of PNI...
  20. doi request reprint How do general dentists and orthodontists determine where to refer patients requiring oral and maxillofacial surgical procedures?
    Thomas Schlieve
    Clinical Assistant Professor, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL
    J Oral Maxillofac Surg 73:509-13. 2015
    ..This study investigated the influence of specific criteria on referral selection among general dentists and orthodontists in deciding referrals to oral and maxillofacial surgeons...
  21. doi request reprint Metastatic pancreatic adenocarcinoma to the mandibular condyle: a rare clinical presentation
    Antonia Kolokythas
    Assistant Professor, Department of Oral and Maxillofacial Surgery, and member, Cancer Center, University of Illinois at Chicago, Chicago, IL Electronic address
    J Oral Maxillofac Surg 72:83-8. 2014
    ..Additionally, in approximately 33% of cases, the oral metastatic lesion may be the first indication of an undiscovered distant primary tumor, making timely evaluation and treatment critical from an oncologic perspective. ..
  22. doi request reprint Use of virtual surgery and stereolithography-guided osteotomy for mandibular reconstruction with the free fibula
    Anuja K Antony
    Division of Plastic and Reconstructive Surgery and the Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, and Virtual Surgical Planning Services, Medical Modeling, Inc, Chicago, IL 60612, USA
    Plast Reconstr Surg 128:1080-4. 2011
    ..The authors feel this technology facilitates realization of technical accuracy, aesthetic contour, and functional outcomes and may be particularly useful if free fibular mandibular reconstruction is performed less frequently...
  23. ncbi request reprint Surgical salvage for local and regional recurrence in oral cancer
    Robert A Ord
    Department of Oral and Maxillofacial Surgery, University of Maryland, Greenbaum Cancer Center, Baltimore, MD 21201 1754, USA
    J Oral Maxillofac Surg 64:1409-14. 2006
    ..To evaluate local and regional recurrence and the outcomes for salvage surgery in patients for oral cancer...
  24. doi request reprint Mandibular osteotomies for access to select parapharyngeal space neoplasms
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, University of California, San Francisco, California, USA
    Head Neck 31:102-10. 2009
    ..Tumors involving the parapharyngeal space present a challenge of surgical access...
  25. doi request reprint Does Restriction of Public Health Care Dental Benefits Affect the Volume, Severity, or Cost of Dental-Related Hospital Visits?
    David Salomon
    Resident, Department of Oral and Maxillofacial Surgery, University of Illinois, Chicago, IL
    J Oral Maxillofac Surg . 2016
    ..The purpose of this study was to measure the effect of this restriction on the volume, severity, and treatment costs of odontogenic infections in an urban hospital...
  26. doi request reprint Outcomes of Immediate Allograft Reconstruction of Long-Span Defects of the Inferior Alveolar Nerve
    David Salomon
    Resident, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL
    J Oral Maxillofac Surg 74:2507-2514. 2016
    ..The goal of this study was to determine the outcomes of immediate reconstruction of long-span defects (≥50 mm) of the inferior alveolar nerve (IAN) after ablative mandibular resection using allogeneic nerve grafts...
  27. pmc Similar Squamous Cell Carcinoma Epithelium microRNA Expression in Never Smokers and Ever Smokers
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Illinois at Chicago, 801 South Paulina Street, Chicago, Illinois, 60610, United States of America
    PLoS ONE 10:e0141695. 2015
    ..It implies that there may be great similarity in etiology of OSCC in never and ever smokers and that classifying OSCC based on tobacco exposure may not be helpful in the clinic. ..
  28. doi request reprint Is immediate reconstruction of the mandible with nonvascularized bone graft following resection of benign pathology a viable treatment option?
    Thomas Schlieve
    Clinical Assistant Professor, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL Electronic address
    J Oral Maxillofac Surg 73:541-9. 2015
    ....
  29. doi request reprint Streptococci-human papilloma virus interaction with ethanol exposure leads to keratinocyte damage
    Joel Schwartz
    Department of Oral Medicine and Diagnostic Sciences, and member, University of Illinois Cancer Center, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Oral Maxillofac Surg 70:1867-79. 2012
    ..This cell study examines whether Streptococci sp and HPV-16 with exposure to ethyl alcohol (ETOH) can act as cofactors in the malignant transformation of oral keratinocytes...
  30. ncbi request reprint Primary intraosseous odontogenic carcinoma arising in an odontogenic cyst or de novo: a clinicopathologic study of six new cases
    Risa Chaisuparat
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore, MD, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:194-200. 2006
    ..Knowledge of the clinical, radiographic, and histopathologic features of PIOC allows accurate diagnosis and appropriate treatment of this rare malignancy...
  31. doi request reprint Cervical necrotizing fasciitis with descending mediastinitis: literature review and case report
    Thomas Sarna
    Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Oral Maxillofac Surg 70:1342-50. 2012
    ..Despite the technologic advances in diagnosis and treatment, CNF complicated by DNM mediastinitis and sepsis still results in astoundingly high mortality...
  32. doi request reprint Lingual Nerve Repair: To Graft or Not to Graft?
    Michael Miloro
    Professor and Head, Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago College of Dentistry, Chicago, IL Electronic address
    J Oral Maxillofac Surg 73:1844-50. 2015
    ....
  33. doi request reprint Inferior alveolar and lingual nerve imaging
    Michael Miloro
    Department of Oral and Maxillofacial Surgery, University of Illinois at Chicago, 801 South Paulina Street, Chicago, IL 60612, USA
    Atlas Oral Maxillofac Surg Clin North Am 19:35-46. 2011
    ....
  34. pmc Alveolar osteitis: a comprehensive review of concepts and controversies
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Illinois at Chicago, 801 South Paulina Street, MC 835, Chicago, IL 60016, USA
    Int J Dent 2010:249073. 2010
    ..We aim to assist the dental health care professional with patient preparation and management of this commonly encountered postoperative condition should be encountered...
  35. pmc Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma
    Lu Jiang
    Center for Molecular Biology of Oral Diseases, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA
    Int J Cancer 127:505-12. 2010
    ....
  36. doi request reprint Analysis of RNA from brush cytology detects changes in B2M, CYP1B1 and KRT17 levels with OSCC in tobacco users
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, College of Dentistry, and University of Illinois at Chicago, 801 South Paulina Street, Chicago, IL 60610, USA
    Oral Oncol 47:532-6. 2011
    ....
  37. pmc Validation of the University of California San Francisco Oral Cancer Pain Questionnaire
    Antonia Kolokythas
    Department of Oral and Maxillofacial Surgery, University of California San Francisco, California 94143 0440, USA
    J Pain 8:950-3. 2007
    ..PERSPECTIVE: The study validates an oral cancer pain questionnaire. The questionnaire can be used to reliably measure pain levels before and after surgical resection in patients with oral cancer...