Abbas E Kitabchi

Summary

Publications

  1. pmc Effects of high-protein versus high-carbohydrate diets on markers of β-cell function, oxidative stress, lipid peroxidation, proinflammatory cytokines, and adipokines in obese, premenopausal women without diabetes: a randomized controlled trial
    Abbas E Kitabchi
    Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Diabetes Care 36:1919-25. 2013
  2. doi request reprint Safety of rapid-acting insulin analogs versus regular human insulin
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, 38163, USA
    Am J Med Sci 344:136-41. 2012
  3. ncbi request reprint Hyperglycemia-induced activation of human T-lymphocytes with de novo emergence of insulin receptors and generation of reactive oxygen species
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 335:491-5. 2005
  4. pmc Effects of intravenous glucose load on insulin secretion in patients with ketosis-prone diabetes during near-normoglycemia remission
    Aidar R Gosmanov
    Department of Medicine, Emory University, Atlanta, Georgia, USA
    Diabetes Care 33:854-60. 2010
  5. pmc Thirty years of personal experience in hyperglycemic crises: diabetic ketoacidosis and hyperglycemic hyperosmolar state
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes, and Metabolism, University of Tennessee Health Science Center, 920 Madison Avenue 909, Memphis, TN 38163, USA
    J Clin Endocrinol Metab 93:1541-52. 2008
  6. pmc Lack of lipotoxicity effect on {beta}-cell dysfunction in ketosis-prone type 2 diabetes
    Guillermo E Umpierrez
    Department of Medicine, Emory University, Atlanta, Georgia, USA
    Diabetes Care 33:626-31. 2010
  7. ncbi request reprint Diabetic ketoacidosis induces in vivo activation of human T-lymphocytes
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 315:404-7. 2004
  8. pmc Is a priming dose of insulin necessary in a low-dose insulin protocol for the treatment of diabetic ketoacidosis?
    Abbas E Kitabchi
    Department of Medicine and Molecular Sciences, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Diabetes Care 31:2081-5. 2008
  9. ncbi request reprint Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation
    Frankie B Stentz
    Division of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 346:721-6. 2006
  10. ncbi request reprint Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Diabetes 53:2079-86. 2004

Detail Information

Publications35

  1. pmc Effects of high-protein versus high-carbohydrate diets on markers of β-cell function, oxidative stress, lipid peroxidation, proinflammatory cytokines, and adipokines in obese, premenopausal women without diabetes: a randomized controlled trial
    Abbas E Kitabchi
    Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Diabetes Care 36:1919-25. 2013
    ....
  2. doi request reprint Safety of rapid-acting insulin analogs versus regular human insulin
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, 38163, USA
    Am J Med Sci 344:136-41. 2012
    ..This review will describe the similarities and differences between the safety profiles of rapid-acting insulin analogs...
  3. ncbi request reprint Hyperglycemia-induced activation of human T-lymphocytes with de novo emergence of insulin receptors and generation of reactive oxygen species
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 335:491-5. 2005
    ..We propose that activation of T-cells with development of insulin receptors in hyperglycemic conditions may serve as a mechanism for control of glucose entry into these cells, thus, protecting them against glucose toxicity...
  4. pmc Effects of intravenous glucose load on insulin secretion in patients with ketosis-prone diabetes during near-normoglycemia remission
    Aidar R Gosmanov
    Department of Medicine, Emory University, Atlanta, Georgia, USA
    Diabetes Care 33:854-60. 2010
    ..The aim of this study was to determine the effect of glucotoxicity on beta-cell function during remission in obese patients with KPD...
  5. pmc Thirty years of personal experience in hyperglycemic crises: diabetic ketoacidosis and hyperglycemic hyperosmolar state
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes, and Metabolism, University of Tennessee Health Science Center, 920 Madison Avenue 909, Memphis, TN 38163, USA
    J Clin Endocrinol Metab 93:1541-52. 2008
    ..This paper summarizes the results of these prospective studies on the management and pathophysiology of DKA...
  6. pmc Lack of lipotoxicity effect on {beta}-cell dysfunction in ketosis-prone type 2 diabetes
    Guillermo E Umpierrez
    Department of Medicine, Emory University, Atlanta, Georgia, USA
    Diabetes Care 33:626-31. 2010
    ..A high FFA level by intralipid infusion for 48 h was not associated with beta-cell decompensation (lipotoxicity) in KPDM patients...
  7. ncbi request reprint Diabetic ketoacidosis induces in vivo activation of human T-lymphocytes
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 315:404-7. 2004
    ..We propose DKA changes the T-lymphocytes to insulin sensitive tissues as a compensatory mechanism...
  8. pmc Is a priming dose of insulin necessary in a low-dose insulin protocol for the treatment of diabetic ketoacidosis?
    Abbas E Kitabchi
    Department of Medicine and Molecular Sciences, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Diabetes Care 31:2081-5. 2008
    ..The purpose of this study was to assess the efficacy of an insulin priming dose with a continuous insulin infusion versus two continuous infusions without a priming dose...
  9. ncbi request reprint Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation
    Frankie B Stentz
    Division of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Biochem Biophys Res Commun 346:721-6. 2006
    ..We hypothesize that these events may serve as protective defense mechanisms against acute effects of glucotoxicity and lipotoxicity in these cells...
  10. ncbi request reprint Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Diabetes 53:2079-86. 2004
    ..Return of these values to normal levels with insulin therapy demonstrates a robust anti-inflammatory effect of insulin...
  11. ncbi request reprint Transcriptome and proteome expression in activated human CD4 and CD8 T-lymphocytes
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN, USA
    Biochem Biophys Res Commun 324:692-6. 2004
    ..To our knowledge this is the first report of an hitherto unreported event. Possible implications of these processes are discussed in the light of their physiological significance...
  12. ncbi request reprint Active use of cocaine: an independent risk factor for recurrent diabetic ketoacidosis in a city hospital
    Ebenezer A Nyenwe
    Department of Medicine, Bronx Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, New York, USA
    Endocr Pract 13:22-9. 2007
    ..To identify the risk factors for recurrent diabetic ketoacidosis (DKA) in a city hospital...
  13. pmc Transcriptome and proteome expressions involved in insulin resistance in muscle and activated T-lymphocytes of patients with type 2 diabetes
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Genomics Proteomics Bioinformatics 5:216-35. 2007
    ..These alterations in transcriptomes and proteomes in T2DM may be involved in insulin resistance...
  14. ncbi request reprint De novo emergence of growth factor receptors in activated human CD4+ and CD8+ T lymphocytes
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Tennessee Health Science Center, Memphis 38163, USA
    Metabolism 53:117-22. 2004
    ....
  15. ncbi request reprint Hyperglycemic crises in adult patients with diabetes: a consensus statement from the American Diabetes Association
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, 956 Court Ave, Suite D334, Memphis, Tennessee 38163, USA
    Diabetes Care 29:2739-48. 2006
  16. ncbi request reprint Hyperglycemic crises in diabetes mellitus: diabetic ketoacidosis and hyperglycemic hyperosmolar state
    Abbas E Kitabchi
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Endocrinol Metab Clin North Am 35:725-51, viii. 2006
    ..DKA and HHS also are economically burdensome; therefore, any resources invested in their prevention would be rewarding...
  17. ncbi request reprint De novo emergence of insulin-stimulated glucose uptake in human aortic endothelial cells incubated with high glucose
    Aidar R Gosmanov
    Department of Medicine, The University of Tennessee Health Science Center, 956 Court Ave, Suite D334, Memphis, TN 38163, USA
    Am J Physiol Endocrinol Metab 290:E516-22. 2006
    ....
  18. pmc A comparison study of continuous insulin infusion protocols in the medical intensive care unit: computer-guided vs. standard column-based algorithms
    Christopher A Newton
    Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
    J Hosp Med 5:432-7. 2010
    ..To compare the safety and efficacy of continuous insulin infusion (CII) via a computer-guided and a standard paper form protocol in a medical intensive care unit (ICU)...
  19. pmc Menopause and risk of diabetes in the Diabetes Prevention Program
    Catherine Kim
    Department of Medicine, University of Michigan, Ann Arbor, MI, USA
    Menopause 18:857-68. 2011
    ..The study objectives were to examine the association between menopause status and diabetes risk among women with glucose intolerance and to determine if menopause status modifies response to diabetes prevention interventions...
  20. pmc Intravenous intralipid-induced blood pressure elevation and endothelial dysfunction in obese African-Americans with type 2 diabetes
    Guillermo E Umpierrez
    Department of Medicine, General Clinical Research Center, Emory University School of Medicine, 49 Jesse Hill Jr Drive, Atlanta, Georgia 30303, USA
    J Clin Endocrinol Metab 94:609-14. 2009
    ..We evaluated the effect of sustained elevations of FFA on blood pressure, endothelial function, insulin secretion, inflammatory markers, and renin-angiotensin system...
  21. doi request reprint Proinflammatory cytokines in response to insulin-induced hypoglycemic stress in healthy subjects
    Laleh Razavi Nematollahi
    The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Metabolism 58:443-8. 2009
    ..Elevations of NE, EP, corticotropin, and cortisol in hypoglycaemia are associated with the elevation of the proinflammatory cytokines and leukocytosis...
  22. ncbi request reprint Treatment of diabetic ketoacidosis with subcutaneous insulin aspart
    Guillermo E Umpierrez
    Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
    Diabetes Care 27:1873-8. 2004
    ....
  23. ncbi request reprint Evidence for strict inpatient blood glucose control: time to revise glycemic goals in hospitalized patients
    Abbas E Kitabchi
    University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Metabolism 57:116-20. 2008
    ..We propose a more conservative approach of glycemic control than current American Association of Clinical Endocrinology recommendations until results of prospective, multicenter, randomized studies become available...
  24. pmc Management of type 2 diabetes: evolving strategies for the treatment of patients with type 2 diabetes
    Ebenezer A Nyenwe
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Metabolism 60:1-23. 2011
    ..A review of the evidence supporting the efficacy of the different preventive measures is also provided...
  25. ncbi request reprint Risk of new-onset diabetes mellitus and worsening glycaemic variables for established diabetes in men undergoing androgen-deprivation therapy for prostate cancer
    Ithaar H Derweesh
    Department of Urology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    BJU Int 100:1060-5. 2007
    ....
  26. ncbi request reprint Admission hyperglycemia and other risk factors as predictors of hospital mortality in a medical ICU population
    Amado X Freire
    Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, University of Tennessee Health Science Center, Memphis, 38163, USA
    Chest 128:3109-16. 2005
    ..Tight glycemic control is recommended for patients in the ICU, as hyperglycemia is associated with increased morbidity and mortality...
  27. pmc Acidosis: the prime determinant of depressed sensorium in diabetic ketoacidosis
    Ebenezer A Nyenwe
    Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Diabetes Care 33:1837-9. 2010
    ..The etiology of altered sensorium in diabetic ketoacidosis (DKA) remains unclear. Therefore, we sought to determine the origin of depressed consciousness in DKA...
  28. doi request reprint Evidence-based management of hyperglycemic emergencies in diabetes mellitus
    Ebenezer A Nyenwe
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Diabetes Res Clin Pract 94:340-51. 2011
    ..The evidence for the role of preventive measures in DKA and HHS is also discussed. The unanswered questions and future research needs are also highlighted...
  29. ncbi request reprint Diabetic ketoacidosis: risk factors and management strategies
    Guillermo E Umpierrez
    Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Treat Endocrinol 2:95-108. 2003
    ..Novel approaches to patient education incorporating a variety of healthcare beliefs and socioeconomic issues are critical to an effective prevention program...
  30. doi request reprint Venous serum bicarbonate concentration predicts arterial PH in adults with diabetic ketoacidosis
    Ebenezer A Nyenwe
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee
    Endocr Pract 20:201-6. 2014
    ..Therefore, we investigated the utility of venous bicarbonate concentration obtained from a basic metabolic panel in predicting arterial pH in adults with DKA...
  31. pmc Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program
    Allan F Moore
    Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    Diabetes 57:2503-10. 2008
    ....
  32. doi request reprint The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and management
    Ebenezer A Nyenwe
    Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, 920 Madison Ave, Suite 300A, Memphis, TN 38163 Electronic address
    Metabolism 65:507-21. 2016
    ..A brief review of ketosis-prone type 2 diabetes, an update relating to the diagnosis of DKA and a future perspective are also provided. ..
  33. ncbi request reprint Activated T lymphocytes in Type 2 diabetes: implications from in vitro studies
    Frankie B Stentz
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Curr Drug Targets 4:493-503. 2003
    ..Due to the accessibility of obtaining these cells from patients, activated T-lymphocytes offer the potential of studying diabetes and other disease in human subjects...
  34. ncbi request reprint Changes in serum leptin in lean and obese subjects with acute hyperglycemic crises
    Abbas E Kitabchi
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Clin Endocrinol Metab 88:2593-6. 2003
    ..The low serum leptin level on admission in subjects with hyperglycemic crises may be the result of impaired adipocyte glucose utilization due to insulin deficiency and/or to increased catecholamine levels...
  35. pmc Antidepressant medicine use and risk of developing diabetes during the diabetes prevention program and diabetes prevention program outcomes study
    Richard R Rubin
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Diabetes Care 33:2549-51. 2010
    ..To assess the association between antidepressant medicine use and risk of developing diabetes during the Diabetes Prevention Program (DPP) and Diabetes Prevention Program Outcomes Study (DPPOS)...