Sara Kangaspeska

Summary

Publications

  1. pmc Reanalysis of RNA-sequencing data reveals several additional fusion genes with multiple isoforms
    Sara Kangaspeska
    Institute for Molecular Medicine Finland, Helsinki, Finland
    PLoS ONE 7:e48745. 2012
  2. pmc Identification of fusion genes in breast cancer by paired-end RNA-sequencing
    Henrik Edgren
    Institute for Molecular Medicine Finland, Tukholmankatu 8, Helsinki, 00290, Finland
    Genome Biol 12:R6. 2011
  3. pmc Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer
    Sara Kangaspeska
    Institute for Molecular Medicine Finland FIMM, Biomedicum 2U, Tukholmankatu 8, 00290, Helsinki, Finland
    BMC Cancer 16:378. 2016
  4. doi KRAS oncogene rearrangements and gene fusions: unexpected rare encounters in late-stage prostate cancers
    Henrik Edgren
    Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland
    Cancer Discov 1:12-3. 2011

Detail Information

Publications4

  1. pmc Reanalysis of RNA-sequencing data reveals several additional fusion genes with multiple isoforms
    Sara Kangaspeska
    Institute for Molecular Medicine Finland, Helsinki, Finland
    PLoS ONE 7:e48745. 2012
    ..This illustrates the importance of reanalyzing sequencing data as gene definitions change and bioinformatic methods improve, and highlights the previously unforeseen isoform diversity among fusion transcripts...
  2. pmc Identification of fusion genes in breast cancer by paired-end RNA-sequencing
    Henrik Edgren
    Institute for Molecular Medicine Finland, Tukholmankatu 8, Helsinki, 00290, Finland
    Genome Biol 12:R6. 2011
    ..Next-generation sequencing technologies provide an opportunity for systematic characterization of cancer cell transcriptomes, including the discovery of expressed fusion genes resulting from underlying genomic rearrangements...
  3. pmc Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer
    Sara Kangaspeska
    Institute for Molecular Medicine Finland FIMM, Biomedicum 2U, Tukholmankatu 8, 00290, Helsinki, Finland
    BMC Cancer 16:378. 2016
    ..Here, we report the generation and characterization of seven tamoxifen-resistant breast cancer cell lines from four parental strains...
  4. doi KRAS oncogene rearrangements and gene fusions: unexpected rare encounters in late-stage prostate cancers
    Henrik Edgren
    Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland
    Cancer Discov 1:12-3. 2011
    ..Wang and colleagues identify a fusion between UBE2L3 and KRAS in a subset of metastatic prostate cancers...