Graeme Jones

Summary

Publications

  1. ncbi request reprint A randomized controlled trial of phytoestrogen supplementation, growth and bone turnover in adolescent males
    G Jones
    Menzies Centre for Population Health Research, Hobart, Tasmania, Australia
    Eur J Clin Nutr 57:324-7. 2003
  2. ncbi request reprint Bone density interpretation and relevance in Caucasian children aged 9-17 years of age: insights from a population-based fracture study
    Graeme Jones
    Menzies Research Institute, Hobart, Tasmania, Australia
    J Clin Densitom 9:202-9. 2006
  3. pmc Familial, structural, and environmental correlates of MRI-defined bone marrow lesions: a sibpair study
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Level 2, Surrey House, 199 Macquarie Street, Hobart, TAS 7000, Australia
    Arthritis Res Ther 8:R137. 2006
  4. ncbi request reprint Meniscal tear as an osteoarthritis risk factor in a largely non-osteoarthritic cohort: a cross-sectional study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Rheumatol 34:776-84. 2007
  5. doi request reprint The association between objectively measured physical activity and knee structural change using MRI
    Dawn A Doré
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Ann Rheum Dis 72:1170-5. 2013
  6. ncbi request reprint The genetic contribution and relevance of knee cartilage defects: case-control and sib-pair studies
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7000, Australia
    J Rheumatol 32:1937-42. 2005
  7. doi request reprint Subchondral bone and cartilage damage: a prospective study in older adults
    Dawn Dore
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 62:1967-73. 2010
  8. ncbi request reprint Natural history of knee cartilage defects and factors affecting change
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart
    Arch Intern Med 166:651-8. 2006
  9. ncbi request reprint Correlates of knee pain in younger subjects
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, 7001, Australia
    Clin Rheumatol 26:75-80. 2007
  10. doi request reprint Associations between serum levels of inflammatory markers and change in knee pain over 5 years in older adults: a prospective cohort study
    Oliver P Stannus
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Ann Rheum Dis 72:535-40. 2013

Detail Information

Publications108 found, 100 shown here

  1. ncbi request reprint A randomized controlled trial of phytoestrogen supplementation, growth and bone turnover in adolescent males
    G Jones
    Menzies Centre for Population Health Research, Hobart, Tasmania, Australia
    Eur J Clin Nutr 57:324-7. 2003
    ..To assess the effect of phytoestrogens on bone turnover and growth in adolescent boys...
  2. ncbi request reprint Bone density interpretation and relevance in Caucasian children aged 9-17 years of age: insights from a population-based fracture study
    Graeme Jones
    Menzies Research Institute, Hobart, Tasmania, Australia
    J Clin Densitom 9:202-9. 2006
    ..Five-yr wrist and forearm fracture risk has potential as a clinical endpoint of immediate relevance...
  3. pmc Familial, structural, and environmental correlates of MRI-defined bone marrow lesions: a sibpair study
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Level 2, Surrey House, 199 Macquarie Street, Hobart, TAS 7000, Australia
    Arthritis Res Ther 8:R137. 2006
    ..They commonly coexist with chondral defects and ROA but only share common genetic mechanisms to a limited degree. They are also more common with increasing age, male sex, and increasing BMI...
  4. ncbi request reprint Meniscal tear as an osteoarthritis risk factor in a largely non-osteoarthritic cohort: a cross-sectional study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Rheumatol 34:776-84. 2007
    ..To examine the associations between meniscal tear, knee structure, osteoarthritis (OA) risk factors, radiographic change, and symptoms in a largely non-osteoarthritic cohort...
  5. doi request reprint The association between objectively measured physical activity and knee structural change using MRI
    Dawn A Doré
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Ann Rheum Dis 72:1170-5. 2013
    ..This study describes the longitudinal association between objectively assessed physical activity (PA) and knee structural change measured using MRI...
  6. ncbi request reprint The genetic contribution and relevance of knee cartilage defects: case-control and sib-pair studies
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7000, Australia
    J Rheumatol 32:1937-42. 2005
    ....
  7. doi request reprint Subchondral bone and cartilage damage: a prospective study in older adults
    Dawn Dore
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 62:1967-73. 2010
    ..The aim of this study was to describe the association between baseline tibial bone area and tibial subchondral bone mineral density (BMD) with tibial cartilage defect development and cartilage volume loss...
  8. ncbi request reprint Natural history of knee cartilage defects and factors affecting change
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart
    Arch Intern Med 166:651-8. 2006
    ..Knee cartilage defects may play an important role in early osteoarthritis, but little is known about their natural history...
  9. ncbi request reprint Correlates of knee pain in younger subjects
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, 7001, Australia
    Clin Rheumatol 26:75-80. 2007
    ..MRI and biochemical measures can add to radiographs in defining unexplained knee pain in younger subjects...
  10. doi request reprint Associations between serum levels of inflammatory markers and change in knee pain over 5 years in older adults: a prospective cohort study
    Oliver P Stannus
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Ann Rheum Dis 72:535-40. 2013
    ..To determine the association between inflammatory markers and change in knee pain over 5 years...
  11. pmc The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study
    Oliver P Stannus
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Arthritis Res Ther 12:R95. 2010
    ..The aim of this study was to describe the associations between leptin, IL-6, and hip radiographic osteoarthritis (ROA) in older adults...
  12. ncbi request reprint Association of prevalent and incident knee cartilage defects with loss of tibial and patellar cartilage: a longitudinal study
    Changhai Ding
    University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 52:3918-27. 2005
    ..To describe the association between prevalent and incident knee cartilage defects and loss of knee cartilage in male and female adults...
  13. doi request reprint Moderate vitamin D deficiency is associated with changes in knee and hip pain in older adults: a 5-year longitudinal study
    Laura L Laslett
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Ann Rheum Dis 73:697-703. 2014
    ..Vitamin D is important for bone, cartilage and muscle function but there are few studies on its association with joint pain...
  14. doi request reprint Prospective study of self-reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community-dwelling older adults
    David Scott
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Arthritis Care Res (Hoboken) 64:30-7. 2012
    ..To examine the potential role of self-reported joint pain, stiffness, and dysfunction, and radiographic osteoarthritis (ROA), in sarcopenia progression and falls risk in older adults...
  15. doi request reprint Serum levels of vitamin D, sunlight exposure, and knee cartilage loss in older adults: the Tasmanian older adult cohort study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania
    Arthritis Rheum 60:1381-9. 2009
    ..To determine the associations between serum levels of vitamin D, sunlight exposure, and knee cartilage loss cross-sectionally and longitudinally in older adults...
  16. ncbi request reprint Determinants of skeletal age deviation in a cross-sectional study
    Sandi Powell
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    J Clin Endocrinol Metab 93:521-6. 2008
    ..Skeletal age deviation (SAD) is associated with bone mass and fracture risk in children, but factors determining this are unknown. The aim of this population-based cross-sectional study was to describe the factors associated with SAD...
  17. ncbi request reprint A prospective study of urinary electrolytes and bone turnover in adolescent males
    Graeme Jones
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Clin Nutr 26:619-23. 2007
    ..The aim of this 6-week prospective study was to describe the association between urinary electrolytes and bone turnover markers in a convenience sample of adolescent boys (N = 136, mean age 16 yr)...
  18. pmc Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults
    Dawn Dore
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, 7000, Australia
    Arthritis Res Ther 12:R222. 2010
    ....
  19. ncbi request reprint The genetic contribution to longitudinal changes in knee structure and muscle strength: a sibpair study
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Tasmania, Australia
    Arthritis Rheum 52:2830-4. 2005
    ..To estimate the heritability of longitudinal changes in knee cartilage volume, chondral defects, subchondral bone size, and lower limb muscle strength...
  20. pmc A prospective study of the impact of musculoskeletal pain and radiographic osteoarthritis on health related quality of life in community dwelling older people
    Laura L Laslett
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, TAS, Australia
    BMC Musculoskelet Disord 13:168. 2012
    ..Pain and radiographic changes are common in persons with osteoarthritis, but their relative contributions to quality of life are unknown...
  21. doi request reprint The association between jockey experience and race-day falls in flat racing in Australia
    Peta L Hitchens
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Inj Prev 18:385-91. 2012
    ..The authors describe rates of occurrence and investigate risk factors for falls among less-experienced thoroughbred flat racing jockeys in Australia who commenced their race riding career between August 2002 and July 2009...
  22. pmc Bone density testing: an under-utilised and under-researched health education tool for osteoporosis prevention?
    Tania Winzenberg
    Menzies Research Institute, Private Bag 23, Hobart TAS 7001, Australia
    Nutrients 2:985-96. 2010
    ..2, 3.3). Fracture risk feedback based on BMD could potentially make an important contribution to osteoporosis prevention but confirmation of long-term benefits and cost effectiveness is needed before implementation can be recommended...
  23. ncbi request reprint Knee structural alteration and BMI: a cross-sectional study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Obes Res 13:350-61. 2005
    ..To describe the associations among BMI, knee cartilage morphology, and bone size in adults...
  24. ncbi request reprint Smoking interacts with family history with regard to change in knee cartilage volume and cartilage defect development
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 56:1521-8. 2007
    ..To describe the effects of smoking on change in knee cartilage volume and increases in knee cartilage defects, and to test for interaction between smoking and family history of osteoarthritis (OA)...
  25. pmc Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults
    Dawn Dore
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, 7000, Australia
    Arthritis Res Ther 12:R223. 2010
    ....
  26. ncbi request reprint A longitudinal study of the association between knee alignment and change in cartilage volume and chondral defects in a largely non-osteoarthritic population
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Rheumatol 34:181-6. 2007
    ..We investigated whether baseline malalignment of the knee predicts subsequent change in knee cartilage volume and chondral defects in subjects with and without radiographic knee osteoarthritis (OA)...
  27. doi request reprint Knee and hip radiographic osteoarthritis predict total hip bone loss in older adults: a prospective study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Bone Miner Res 25:858-65. 2010
    ..In conclusion, older subjects with radiographic hip and knee OA have higher total hip bone loss over 2.6 years regardless of symptoms, suggesting that consideration should be given to the monitoring of bone mass in these subjects...
  28. ncbi request reprint Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen breakdown
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Osteoarthritis Cartilage 13:198-205. 2005
    ..To generate hypotheses regarding the associations between knee cartilage defects and knee radiographic osteoarthritis (ROA), cartilage volume, bone size and type II collagen breakdown in adults...
  29. pmc A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee
    Dawn Dore
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, Tasmania, 7000, Australia
    Arthritis Res Ther 14:R13. 2012
    ..Bone marrow lesions (BMLs) play an important role in knee osteoarthritis, but their etiology is not well understood. The aim of this longitudinal study was to describe the association between dietary factors, serum lipids, and BMLs...
  30. ncbi request reprint Correlates of knee pain in older adults: Tasmanian Older Adult Cohort Study
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7001, Australia
    Arthritis Rheum 55:264-71. 2006
    ..To describe the association between chondral defects, bone marrow lesions, knee and hip radiographic osteoarthritis (OA), and knee pain...
  31. ncbi request reprint Calcium supplements in healthy children do not affect weight gain, height, or body composition
    Tania Winzenberg
    Menzies Research Institute, Private Bag 23, Hobart, TAS 7001 Australia
    Obesity (Silver Spring) 15:1789-98. 2007
    ..The aim of this study was to use data from randomized controlled trials to determine whether calcium supplementation in healthy children affects weight or body composition...
  32. ncbi request reprint A longitudinal study of the effect of sex and age on rate of change in knee cartilage volume in adults
    Changhai Ding
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Rheumatology (Oxford) 46:273-9. 2007
    ..To describe the association between sex, age and rate of change in knee cartilage volume in adults...
  33. doi request reprint Correlates of subchondral BMD: a cross-sectional study
    Dawn Dore
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Bone Miner Res 24:2007-15. 2009
    ..10, p < 0.01). In conclusion, this study identified a large number of factors associated with sBMD, of which the most novel is cartilage defects. Longitudinal studies are required to address causality...
  34. pmc Hypointense signals in the infrapatellar fat pad assessed by magnetic resonance imaging are associated with knee symptoms and structure in older adults: a cohort study
    Weiyu Han
    Menzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia
    Arthritis Res Ther 18:234. 2016
    ..This study aims to describe the associations between hypointense signals in the infrapatellar fat pad (IPFP) and knee structural change and symptoms in older adults...
  35. doi request reprint Association between MRI-detected osteophytes and changes in knee structures and pain in older adults: A cohort study
    Zhaohua Zhu
    Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia
    Osteoarthritis Cartilage . 2017
    ..To describe cross-sectional and longitudinal associations between magnetic resonance imaging (MRI)-detected osteophytes (OPs) and knee structural abnormalities and knee pain in older adults...
  36. doi request reprint Cross-Sectional and Longitudinal Associations Between Serum Levels of High-Sensitivity C-Reactive Protein, Knee Bone Marrow Lesions, and Knee Pain in Patients With Knee Osteoarthritis
    Zhaohua Zhu
    Zhaohua Zhu, MD Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia, and Arthritis Research Institute, Anhui Medical University, Hefei, Anhui, China
    Arthritis Care Res (Hoboken) 68:1471-7. 2016
    ..To describe associations between serum high-sensitivity C-reactive protein (hsCRP), knee bone marrow lesions (BMLs), and knee pain, cross-sectionally and longitudinally, in patients with knee osteoarthritis (OA)...
  37. doi request reprint Correlation Between Changes in Global Knee Structures Assessed by Magnetic Resonance Imaging and Radiographic Osteoarthritis Changes Over Ten Years in a Midlife Cohort
    Hussain Ijaz Khan
    Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Care Res (Hoboken) 68:958-64. 2016
    ..The aim of this study was to describe the correlation between changes in structural abnormalities assessed on magnetic resonance imaging (MRI) and change in radiographic osteoarthritis (OA) over 10 years in a midlife cohort...
  38. doi request reprint Signal intensity alteration in the infrapatellar fat pad at baseline for the prediction of knee symptoms and structure in older adults: a cohort study
    Weiyu Han
    Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia Department of Orthopaedics, 3rd Affiliated Hospital of Southern Medical University, Guangzhou, China
    Ann Rheum Dis 75:1783-8. 2016
    ..To describe the associations between infrapatellar fat pad (IPFP) signal intensity alteration at baseline and knee symptoms and structural changes in older adults...
  39. doi request reprint Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis: A Randomized Clinical Trial
    Xingzhong Jin
    Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia
    JAMA 315:1005-13. 2016
    ..Observational studies suggest that vitamin D supplementation is associated with benefits for knee osteoarthritis, but current trial evidence is contradictory...
  40. pmc Association of physical activity and physical performance with tibial cartilage volume and bone area in young adults
    Benny Antony
    Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
    Arthritis Res Ther 17:298. 2015
    ..The aim of this study was to describe the associations between physical activity and performance measured 5 years prior and tibial cartilage volume and bone area in young adults...
  41. pmc Correlates of knee bone marrow lesions in younger adults
    Benny Antony
    Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool Street, Hobart, TAS 7000, Australia
    Arthritis Res Ther 18:31. 2016
    ....
  42. doi request reprint Quantitative Assessment of Knee Effusion-Synovitis in Older Adults: Association With Knee Structural Abnormalities
    Xia Wang
    Menzies Institute for Medical Research and University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheumatol 68:837-44. 2016
    ....
  43. doi request reprint Childhood Physical Performance Measures and Adulthood Knee Cartilage Volume and Bone Area: A 25-Year Cohort Study
    Benny Antony
    University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Care Res (Hoboken) 67:1263-71. 2015
    ..We aimed to determine the associations between childhood physical performance measures and tibial cartilage volume and tibial bone area in adults 25 years later...
  44. doi request reprint Association of Body Composition and Hormonal and Inflammatory Factors With Tibial Cartilage Volume and Sex Difference in Cartilage Volume in Young Adults
    Benny Antony
    Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
    Arthritis Care Res (Hoboken) 68:517-25. 2016
    ....
  45. doi request reprint Association between childhood overweight measures and adulthood knee pain, stiffness and dysfunction: a 25-year cohort study
    Benny Antony
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia
    Ann Rheum Dis 74:711-7. 2015
    ..To describe the associations between overweight measures in childhood and knee pain, stiffness and dysfunction among adults 25 years later...
  46. doi request reprint Body fat predicts an increase and limb muscle strength predicts a decrease in leptin in older adults over 2·6 years
    Benny Antony
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Clin Endocrinol (Oxf) 79:652-60. 2013
    ..The aim of this study was to determine if body fat and muscle measures predict the natural increase in leptin over 2·6 years in older adults...
  47. doi request reprint Association between hip and knee cartilage measured using radiographs and magnetic resonance imaging: the Tasmanian Older Adult Cohort Study
    Hussain I Khan
    Musculoskeletal Unit, Menzies Research Institute, Medical Science 1 Building, Private Bag 23, 17 Liverpool Street, Hobart, Tasmania 7000, Australia
    Rheumatology (Oxford) 52:2009-15. 2013
    ..The aim of this study was to examine the association of hip and knee cartilage measured by both radiography and MRI...
  48. pmc Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial
    Yuelong Cao
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia
    Trials 13:131. 2012
    ....
  49. doi request reprint The association between parity and knee cartilage in young women
    Shuying Wei
    Menzies Research Institute Tasmania, 17 Liverpool Street, Hobart, Tasmania 7001, Australia
    Rheumatology (Oxford) 51:2039-45. 2012
    ..The aim of this study was to describe the association between parity, cartilage volume and cartilage defects in women aged 31-41 years...
  50. doi request reprint Association of baseline knee bone size, cartilage volume, and body mass index with knee cartilage loss over time: a longitudinal study in younger or middle-aged adults
    Benny Antony
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    J Rheumatol 38:1973-80. 2011
    ..To determine the association of knee bone size, cartilage volume, and body mass index (BMI) at baseline with knee cartilage loss over 2 years in younger or middle-aged adults...
  51. doi request reprint Do NSAIDs affect longitudinal changes in knee cartilage volume and knee cartilage defects in older adults?
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Am J Med 122:836-42. 2009
    ..The aim of this longitudinal study was to determine the associations between use of NSAIDs and changes in knee cartilage volume and knee cartilage defects over 2.9 years in older adults...
  52. ncbi request reprint Pharmacist-provided quantitative heel ultrasound screening for rural women at risk of osteoporosis
    Mark Naunton
    Faculty of Health Science, Tasmanian School of Pharmacy, University of Tasmania, Tasmania, Australia
    Ann Pharmacother 40:38-44. 2006
    ..Osteoporosis is underdiagnosed, and rural communities often have limited technical resources for the assessment of osteoporosis...
  53. doi request reprint Tracking of bone mass from childhood to adolescence and factors that predict deviation from tracking
    Stella Foley
    Menzies Research Institute, University of Tasmania Private Bag 23, Hobart, Tasmania, Australia
    Bone 44:752-7. 2009
    ..Body composition was the main predictor of altered tracking but environmental factors also appear important...
  54. pmc Genetic mechanisms of knee osteoarthritis: a population-based longitudinal study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Arthritis Res Ther 8:R8. 2006
    ..Importantly, the cartilage changes are largely dependent on baseline differences in cartilage volume, tibial bone area, BMI and knee pain, suggesting that these factors might have a role in their initiation...
  55. ncbi request reprint Physical activity and knee structural change: a longitudinal study using MRI
    Stella Foley
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Med Sci Sports Exerc 39:426-34. 2007
    ..Exercise therapy is effective in improving symptoms of knee osteoarthritis, but its effect on structural change remains unclear...
  56. pmc Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort
    Hussain Ijaz Khan
    Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Medical Science 1 Building, Private Bag 23, 17 Liverpool Street, Hobart, TAS, 7000, Australia
    BMC Musculoskelet Disord 17:4. 2016
    ..The aim of this study was to describe the natural history of meniscal tears over 8 years and the relationship with change in knee pain and structures...
  57. pmc Does cartilage volume measurement or radiographic osteoarthritis at baseline independently predict ten-year cartilage volume loss?
    Andrew McBride
    Menzies Institute for Medical Research, University of Tasmania, Medical Science 1 Building, Private Bag 23 17 Liverpool Street, Hobart, 7000, Australia
    BMC Musculoskelet Disord 17:54. 2016
    ..The aim of this study was to examine whether cartilage volume as measured by MRI and radiographic osteoarthritis (OA) at baseline predict cartilage volume loss over ten years independent of each other and other structural co-pathologies...
  58. doi request reprint Longitudinal associations between adiposity and change in knee pain: Tasmanian older adult cohort study
    Xingzhong Jin
    Menzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Semin Arthritis Rheum 45:564-9. 2016
    ..The aim of this study was to describe the longitudinal relationship between adiposity and change in knee pain...
  59. doi request reprint Association between MRI-detected knee joint regional effusion-synovitis and structural changes in older adults: a cohort study
    Xia Wang
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Ann Rheum Dis 75:519-25. 2016
    ..To describe the cross-sectional and longitudinal associations between knee regional effusion-synovitis and structural changes in older adults...
  60. doi request reprint Cross-sectional and longitudinal associations between circulating leptin and knee cartilage thickness in older adults
    Oliver P Stannus
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia
    Ann Rheum Dis 74:82-8. 2015
    ..To investigate cross-sectional and longitudinal associations between serum leptin levels and knee cartilage thickness in older adults...
  61. doi request reprint Association between serum levels of 25-hydroxyvitamin D and osteoarthritis: a systematic review
    Yuelong Cao
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Rheumatology (Oxford) 52:1323-34. 2013
    ..To systematically review the evidence for association between serum 25-hydroxyvitamin D (25-(OH)D) and OA and the effect of vitamin D therapy on OA...
  62. doi request reprint The association between oral contraceptive use, bone mineral density and fractures in women aged 50-80 years
    Shuying Wei
    Menzies Research Institute, University of Tasmania, Hobart, TAS 7001, Australia
    Contraception 84:357-62. 2011
    ..The associations between oral contraceptive (OC) use, bone mineral density (BMD) and the risk of fractures remain controversial...
  63. doi request reprint Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7000, Australia
    J Clin Endocrinol Metab 93:1952-8. 2008
    ..IL-1, IL-6, and TNF-alpha play an important role in the pathogenesis of osteoporosis in animals; however, evidence that these play a similar role in bone loss in human studies is limited...
  64. pmc Menstrual irregularity and bone mass in premenopausal women: cross-sectional associations with testosterone and SHBG
    Shuying Wei
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    BMC Musculoskelet Disord 11:288. 2010
    ..This study aimed to describe the associations between menstrual pattern, testosterone, sex hormone binding globulin (SHBG) and bone mass in a population-based sample of premenopausal women...
  65. pmc Optimal sampling of MRI slices for the assessment of knee cartilage volume for cross-sectional and longitudinal studies
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    BMC Musculoskelet Disord 6:10. 2005
    ..The aim of this study was to determine the optimal sampling of 1.5 mm thick slices of MRI scans to estimate knee cartilage volume in males and females for cross-sectional and longitudinal studies...
  66. ncbi request reprint Factors associated with hip cartilage volume measured by magnetic resonance imaging: the Tasmanian Older Adult Cohort Study
    Guangju Zhai
    University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 52:1069-76. 2005
    ....
  67. doi request reprint A prospective study of the associations between 25-hydroxy-vitamin D, sarcopenia progression and physical activity in older adults
    David Scott
    Menzies Research Institute, University of Tasmania, Hobart School of Human Life Sciences, University of Tasmania, Launceston, TAS, Australia
    Clin Endocrinol (Oxf) 73:581-7. 2010
    ..Our objective was to describe prospective associations between 25OHD, muscle parameters, and PA in community-dwelling older adults...
  68. pmc Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials
    Tania Winzenberg
    Menzies Research Institute, Private Bag 23, Hobart, TAS 7001, Australia
    BMJ 333:775. 2006
    ..To assess the effectiveness of calcium supplementation for improving bone mineral density in healthy children and to determine if any effect is modified by other factors and persists after supplementation stops...
  69. doi request reprint Cross-sectional and longitudinal associations between systemic, subchondral bone mineral density and knee cartilage thickness in older adults with or without radiographic osteoarthritis
    Yuelong Cao
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia Research Institute of Orthopaedics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Ann Rheum Dis 73:2003-9. 2014
    ..To investigate cross-sectional and longitudinal associations between systemic bone mineral density (BMD), subchondral BMD (sBMD) and knee cartilage thickness in older adults with or without radiographic osteoarthritis (ROA)...
  70. pmc The high prevalence of vitamin D insufficiency across Australian populations is only partly explained by season and latitude
    Ingrid A F van der Mei
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Environ Health Perspect 115:1132-9. 2007
    ..Inadequate sun exposure and dietary vitamin D intake can result in vitamin D insufficiency. However, limited data are available on actual vitamin D status and predictors in healthy individuals in different regions and by season...
  71. doi request reprint Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial
    Laura Louise Laslett
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Ann Rheum Dis 71:1322-8. 2012
    ..To compare the effect of a single infusion of zoledronic acid (ZA) with placebo on knee pain and bone marrow lesions (BMLs)...
  72. doi request reprint Physical activity and osteoarthritis of the knee: can MRI scans shed more light on this issue?
    Graeme Jones
    Menzies Research Institute Tasmania, Tasmania, Australia
    Phys Sportsmed 39:55-61. 2011
    ..In the meantime, it appears safe to prescribe exercise in later life without major concern for structural deterioration, although caution is appropriate in those with bone marrow lesions until more information becomes available...
  73. doi request reprint Ambulatory activity, body composition, and lower-limb muscle strength in older adults
    David Scott
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Med Sci Sports Exerc 41:383-9. 2009
    ..The aim of this study was to describe associations of pedometer-determined AA with body fat and leg muscle parameters in community-dwelling 50- to 79-yr-olds...
  74. ncbi request reprint The genetic contribution to muscle strength, knee pain, cartilage volume, bone size, and radiographic osteoarthritis: a sibpair study
    Guangju Zhai
    University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 50:805-10. 2004
    ..To estimate the heritability of muscle strength, knee pain, cartilage volume, bone size, and radiographic osteoarthritis (ROA), and to assess whether heritability of the knee structural components is independent of ROA...
  75. ncbi request reprint Can BMD assessed by DXA at age 8 predict fracture risk in boys and girls during puberty?: an eight-year prospective study
    Jennifer Flynn
    Menzies Research Institute, Hobart, Tasmania, Australia
    J Bone Miner Res 22:1463-7. 2007
    ..Bone densitometry at the total body and spine (but not hip) is a strong predictor of fracture (especially upper limb) during puberty...
  76. ncbi request reprint Risk-taking, coordination and upper limb fractures in children: a population based case-control study
    Deqiong Ma
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania, Australia 7000
    Osteoporos Int 15:633-8. 2004
    ..These results inform the development of fracture prevention strategies in children...
  77. doi request reprint Predictors of race-day jockey falls in flat racing in Australia
    Peta Lee Hitchens
    Menzies Research Institute, University of Tasmania, Hobart, TAS, Australia
    Occup Environ Med 67:693-8. 2010
    ..Riding thoroughbred racehorses is a hazardous occupation. In this study, we investigated risk factors associated with falls by licensed thoroughbred racing jockeys participating in flat races conducted in Australia...
  78. pmc Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume
    Changhai Ding
    Menzies Research Institute, University of Tasmania, 199 Macquarie Street, Hobart 7000, Australia
    Arthritis Res Ther 9:R21. 2007
    ....
  79. doi request reprint Oral contraceptive use and bone
    Shuying Wei
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Curr Osteoporos Rep 9:6-11. 2011
    ....
  80. ncbi request reprint Dual energy X-ray absorptiometry
    Tania Winzenberg
    Menzies Research Institute, University of Tasmania, Australia
    Aust Fam Physician 40:43-4. 2011
    ..The result - the bone mineral density (BMD) - can be reported at a number of sites. The most clinically useful are the lumbar spine, femoral neck and total hip (also termed the 'proximal femur')...
  81. pmc The effect on behavior and bone mineral density of individualized bone mineral density feedback and educational interventions in premenopausal women: a randomized controlled trial [NCT00273260]
    Tania Winzenberg
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    BMC Public Health 6:12. 2006
    ....
  82. doi request reprint Early life nutrition and bone development in children
    Graeme Jones
    Menzies Research Institute, University of Tasmania, Hobart, TAS, Australia
    Nestle Nutr Workshop Ser Pediatr Program 68:227-33; discussion 233-6. 2011
    ..All of these associations are statistically significant and independent of important confounders and later environmental exposures, suggesting that osteoporosis prevention programs need to start very early in the life cycle...
  83. ncbi request reprint Growth, children, and fractures
    Graeme Jones
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Curr Osteoporos Rep 2:75-8. 2004
    ..While prospective studies are required to confirm these risk factors, accumulating evidence now suggests that a substantial proportion of fractures in children are preventable...
  84. ncbi request reprint A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis
    Velandai K Srikanth
    The Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7001, Australia
    Osteoarthritis Cartilage 13:769-81. 2005
    ..To resolve uncertainty regarding sex differences in osteoarthritis (OA) by performing a meta-analysis of sex differences in OA prevalence, incidence and severity...
  85. doi request reprint Measures of childhood fitness and body mass index are associated with bone mass in adulthood: a 20-year prospective study
    Stella Foley
    Menzies Research Institute, University of Tasmania, Hobart, Hobart, Australia
    J Bone Miner Res 23:994-1001. 2008
    ..These results suggest that increased skeletal loading in childhood leads to an increase in peak bone mass independent of current loading...
  86. ncbi request reprint Anti-interleukin-6 receptor antibody treatment in inflammatory autoimmune diseases
    Changhai Ding
    Menzies Research Institute, Hobart, Tasmania, Australia
    Rev Recent Clin Trials 1:193-200. 2006
    ..Like other anti-cytokine immunotherapies, caution and close monitoring for the adverse events, especially infection, are necessary in subsequent clinical trials...
  87. pmc Effects of vitamin D supplementation on bone density in healthy children: systematic review and meta-analysis
    Tania Winzenberg
    Menzies Research Institute, University of Tasmania, Hobart, TAS, Australia
    BMJ 342:c7254. 2011
    ..To determine the effectiveness of vitamin D supplementation for improving bone mineral density in children and adolescents and if effects vary with factors such as vitamin D dose and vitamin D status...
  88. doi request reprint Associations between dietary nutrient intake and muscle mass and strength in community-dwelling older adults: the Tasmanian Older Adult Cohort Study
    David Scott
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Am Geriatr Soc 58:2129-34. 2010
    ..To describe associations between dietary nutrient intake and progression of sarcopenia, the age-related loss of muscle mass and strength...
  89. ncbi request reprint Television, computer, and video viewing; physical activity; and upper limb fracture risk in children: a population-based case control study
    Deqiong Ma
    Menzies Research Institute, Hobart, Tasmania, Australia
    J Bone Miner Res 18:1970-7. 2003
    ..Sports participation increased fracture risk in boys and decreased risk in girls. Television viewing had a deleterious dose response association with wrist and forearm fractures while light physical activity was protective...
  90. ncbi request reprint The AMBITION trial: tocilizumab monotherapy for rheumatoid arthritis
    Graeme Jones
    Musculoskeletal Unit, Menzies Research Institute, Private Bag 23, Hobart Tasmania 7001, Australia
    Expert Rev Clin Immunol 6:189-95. 2010
    ..Long-term efficacy and safety follow-up is ongoing. This trial supports the use of TCZ as monotherapy and suggests it should be regarded as a first-line biologic therapy...
  91. pmc A randomized single blind crossover trial comparing leather and commercial wrist splints for treating chronic wrist pain in adults
    Jill Thiele
    Occupational Therapy Department, Royal Hobart Hospital, Hobart, Australia
    BMC Musculoskelet Disord 10:129. 2009
    ..To compare the effectiveness of a custom-made leather wrist splint (LS) with a commercially available fabric splint (FS) in adults with chronic wrist pain...
  92. ncbi request reprint How important is MRI for detecting early osteoarthritis?
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Nat Clin Pract Rheumatol 4:4-5. 2008
  93. ncbi request reprint Skeletal age deviation assessed by the Tanner-Whitehouse 2 method is associated with bone mass and fracture risk in children
    Graeme Jones
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Bone 36:352-7. 2005
    ..SAD is simple to measure and gives additional information regarding bone health and fracture risk in children...
  94. ncbi request reprint Vitamin D insufficiency in adolescent males in Southern Tasmania: prevalence, determinants, and relationship to bone turnover markers
    Graeme Jones
    Menzies Research Institute, Private Bag 23, 7000, Hobart, Tasmania, Australia
    Osteoporos Int 16:636-41. 2005
    ..These data suggest that a 25(OH)D3 level of at least 43-55 nmol/l is required for optimal bone health in children...
  95. ncbi request reprint B-cell-targeted therapy for systemic lupus erythematosus: an update
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    BioDrugs 22:239-49. 2008
    ..g. ocrelizumab) and agents that interrupt B-cell/T-cell interactions also have potential, and the efficacy of these, along with rituximab, belimumab and epratuzumab, needs to be determined by randomized controlled trials...
  96. ncbi request reprint Osteoarthritis management of the knee--treatment options post the NSAID cardiotoxicity controversy
    Jan Gartlan
    Menzies Research Institute, University of Tasmania, Australia
    Aust Fam Physician 36:717-8. 2007
    ..This article considers treatment options for osteoarthritis management of the knee post the 'NSAID cardiotoxicity controversy'...
  97. ncbi request reprint The association between bone mineral density, metacarpal morphometry, and upper limb fractures in children: a population-based case-control study
    Deqiong Ma
    Menzies Research Institute, Hobart, Tasmania 7000, Australia
    J Clin Endocrinol Metab 88:1486-91. 2003
    ..The magnitude of this association is somewhat weaker than in adults but suggests that optimizing age-appropriate bone mass will lessen the risk of fracture in children...
  98. ncbi request reprint The association between hormonal and reproductive factors and hand osteoarthritis
    Helen M Cooley
    Menzies Centre for Population Health Research, GPO Box 252 23, Hobart, Tasmania 7000, Australia
    Maturitas 45:257-65. 2003
    ..To describe the association of reproductive and hormonal factors with the presence and severity of hand osteoarthritis (OA) in Tasmanian women...
  99. pmc Cardiovascular risks of calcium supplements in women
    Graeme Jones
    BMJ 336:226-7. 2008
  100. ncbi request reprint Multifaceted educational program increases prescribing of preventive medication for corticosteroid induced osteoporosis
    Mark Naunton
    Tasmanian School of Pharmacy and Menzies Research Institute, Faculty of Health Science, University of Tasmania, Tasmania, Australia
    J Rheumatol 31:550-6. 2004
    ..We performed a controlled trial of a comprehensive educational program aimed at increasing the use of osteoporosis preventive therapy in patients prescribed longterm oral corticosteroids...
  101. ncbi request reprint Oral cyclosporin plus topical corticosteroid therapy diminishes bone mass in children with eczema
    Clarissa C Pedreira
    Department of Endocrinology and Diabetes, Royal Children s Hospital, Parkville, Victoria, Australia
    Pediatr Dermatol 24:613-20. 2007
    ..This effect is likely to lead to a modest increase in the risk of wrist and forearm fractures in children using this agent...