T A John

Summary

Publications

  1. ncbi request reprint Conception of Pharmacological Knowledge and Needs Amongst Nigerian Medical Students at Lagos State University College of Medicine: Implication for Future Biomedical Science in Africa
    Luther Agbonyegbeni Agaga
    Department of Pharmacology, Lagos State University College of Medicine, 1 5, Oba Akinjobi Way, Ikeja, PMB 21266, Ikeja, GRA Lagos
    Niger J Physiol Sci 31:83-91. 2016
  2. ncbi request reprint Some Aspects of the State-of-the-Arts in Biomedical Science Research: A Perspective for Organizational Change in African Academia
    Theresa Adebola John
    Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos
    Niger J Physiol Sci 29:153-63. 2014
  3. ncbi request reprint Important techniques in today's biomedical science research that PhD candidates should be exposed to: a perspective from the FASEB journal
    Theresa Adebola John
    Department of Pharmacology, Lagos State University College of Medicine, Lagos
    Niger J Physiol Sci 28:1-8. 2013
  4. ncbi request reprint Morphologic multiplicity of smooth muscle cell monolayers from extreme lung parenchyma of high-altitude-hypoxia sheep
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, 1 Oba Akinjobi Way, GRA, Ikeja, Lagos, Nigeria
    Afr J Med Med Sci 41:307-12. 2012
  5. pmc Inhibitors caveolin-1 and protein kinase G show differential subcellular colocalization with Nitric oxide synthase
    T J Adebola
    Department of Pharmacology, Lagos State University College of Medicine 1 Oba Akinjobi Way, GRA, Ikeja, Lagos, P M B 21266, Ikeja, Lagos, Nigeria
    Afr Health Sci 11:526-34. 2011
  6. ncbi request reprint A comparison of basic and state-of-the-arts skills sets of biomedical science technical staff in Lagos public universities
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, 1 Oba Akinjobi St GRA, PMB 21266, Ikeja, Lagos, Nigeria
    Afr J Med Med Sci 40:327-37. 2011
  7. ncbi request reprint Protein kinase G may exert pro-degradation inhibition on nitric oxide synthase
    Theresa Adebola John
    Department of Pharmacology, Lagos State University College of Medicine, Lagos, Nigeria
    Niger J Physiol Sci 26:1-6. 2011
  8. pmc A fluorescence-activated cell sorter analysis of the relationship between protein kinase G and endothelial nitric oxide synthase
    Theresa A John
    Department of Pediatrics, Division of Neonatology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California, USA
    Anat Rec (Hoboken) 293:1755-65. 2010
  9. ncbi request reprint Protein kinase G inhibits basal and stimulated nitric oxide synthase activity in neonatal ovine lung microvascular endothelial cells
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
    Afr J Med Med Sci 39:89-98. 2010
  10. ncbi request reprint Effect of chronic high altitude hypoxia on foetal and maternal juxta-alveolar distal pulmonary smooth muscle cells actin and calponin organisation and growth profiles
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
    West Afr J Med 29:388-92. 2010

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Conception of Pharmacological Knowledge and Needs Amongst Nigerian Medical Students at Lagos State University College of Medicine: Implication for Future Biomedical Science in Africa
    Luther Agbonyegbeni Agaga
    Department of Pharmacology, Lagos State University College of Medicine, 1 5, Oba Akinjobi Way, Ikeja, PMB 21266, Ikeja, GRA Lagos
    Niger J Physiol Sci 31:83-91. 2016
    ..Medical students' conception and need for pharmacology werebased on MBBS degree requirements; they lacked knowledge/interest in pharmacology as a science and may not be thepotential trusts for Africa's future pharmacology. ..
  2. ncbi request reprint Some Aspects of the State-of-the-Arts in Biomedical Science Research: A Perspective for Organizational Change in African Academia
    Theresa Adebola John
    Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos
    Niger J Physiol Sci 29:153-63. 2014
    ..5%) grants. The collaborative and multidisciplinary nature and government support are characteristic of biomedical science in the US where research tends to result in solutions to problems and economic benefits. ..
  3. ncbi request reprint Important techniques in today's biomedical science research that PhD candidates should be exposed to: a perspective from the FASEB journal
    Theresa Adebola John
    Department of Pharmacology, Lagos State University College of Medicine, Lagos
    Niger J Physiol Sci 28:1-8. 2013
    ..The most popular statistics testing were various forms of student's t-tests at 0.05 confidence levels and ANOVAs. The GraphPad Prism software was the most frequently used statistic software. ..
  4. ncbi request reprint Morphologic multiplicity of smooth muscle cell monolayers from extreme lung parenchyma of high-altitude-hypoxia sheep
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, 1 Oba Akinjobi Way, GRA, Ikeja, Lagos, Nigeria
    Afr J Med Med Sci 41:307-12. 2012
    ..The cells were characterized by fluorescence immunohistochemistry using a monoclonal antibody against alpha-smooth muscle actin. The monolayer morphologies of the derived stable cell lines were compared...
  5. pmc Inhibitors caveolin-1 and protein kinase G show differential subcellular colocalization with Nitric oxide synthase
    T J Adebola
    Department of Pharmacology, Lagos State University College of Medicine 1 Oba Akinjobi Way, GRA, Ikeja, Lagos, P M B 21266, Ikeja, Lagos, Nigeria
    Afr Health Sci 11:526-34. 2011
    ..Smooth muscle protein kinase G (PKG) is a down-stream effector of NO signaling for relaxation of vascular smooth muscle cells (SMC). The PKG is also found in endothelial cells and it inhibits activated NOS within endothelial cells...
  6. ncbi request reprint A comparison of basic and state-of-the-arts skills sets of biomedical science technical staff in Lagos public universities
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, 1 Oba Akinjobi St GRA, PMB 21266, Ikeja, Lagos, Nigeria
    Afr J Med Med Sci 40:327-37. 2011
    ..In Nigeria, biomedical science has not thrived and the contribution from Nigerian universities, indeed African universities, to publications in global high impact journals is low...
  7. ncbi request reprint Protein kinase G may exert pro-degradation inhibition on nitric oxide synthase
    Theresa Adebola John
    Department of Pharmacology, Lagos State University College of Medicine, Lagos, Nigeria
    Niger J Physiol Sci 26:1-6. 2011
    ..PKG may be a post-activation inhibitor of NOS, possibly important for the degradation of the spent enzyme...
  8. pmc A fluorescence-activated cell sorter analysis of the relationship between protein kinase G and endothelial nitric oxide synthase
    Theresa A John
    Department of Pediatrics, Division of Neonatology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California, USA
    Anat Rec (Hoboken) 293:1755-65. 2010
    ..92 to 217.36 for serine 116 and decreased from 329.27 to 254.03 for threonine 495 phosphorylation. Data indicated that PKG caused both molecular and phosphorylation changes in NOS...
  9. ncbi request reprint Protein kinase G inhibits basal and stimulated nitric oxide synthase activity in neonatal ovine lung microvascular endothelial cells
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
    Afr J Med Med Sci 39:89-98. 2010
    ..Both basal and stimulated NO production is regulated by the downstream activation of PKG by NO-induced 8-Br-cGMP production in endothelial cells...
  10. ncbi request reprint Effect of chronic high altitude hypoxia on foetal and maternal juxta-alveolar distal pulmonary smooth muscle cells actin and calponin organisation and growth profiles
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
    West Afr J Med 29:388-92. 2010
    ..The effect of chronic high altitude hypoxia (CHAH) in the juxta-alveolar region near the air-blood interface is unknown because of the experimental inaccessibility of this region...
  11. ncbi request reprint Effect of the aqueous extract of entandrophragma utile bark on gastric acid secretion in ghosh and schild rat preparations
    Theresa A John
    Department of Pharmacology, Lagos State University College of Medicine, Lagos
    Niger Postgrad Med J 18:111-7. 2011
    ..We investigated the antisecretory effect of the aqueous bark extract of E. utile, a Nigerian traditional medicinal preparation used for ulcers...
  12. ncbi request reprint Driving forces of biomedical science education and research in state-of-the arts academic medical centres: the United States as example
    T A John
    Department of Pharmacology, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
    Afr J Med Med Sci 40:109-18. 2011
    ..However, there is lack of research on the educational process in the basic sciences including training of PhD's while there is ample research on medical education pertaining to training of medical doctors...
  13. ncbi request reprint Facilities available for biomedical science research in the public universities in Lagos, Nigeria
    T A John
    Department of Pharmacology, Lagos Sate University College of Medicine, Lagos
    Niger Postgrad Med J 17:6-14. 2010
    ..2 This work investigated facilities available for modern biomedical research in Lagos public universities to extract culprit factors...
  14. pmc Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung
    T A John
    Department of Pharmacology, University of Illinois College of Medicine and Division of Pulmonary and Critical Care Medicine, Northwestern University Medical School, Chicago, IL 60612, USA
    J Physiol 533:547-59. 2001
    ..Approximately 25 % of instilled (125)I-labelled albumin was cleared from the lung preparations per hour by the displacement-sensitive transport pathway. This component was blocked by filipin...
  15. ncbi request reprint Abrogation of thrombin-induced increase in pulmonary microvascular permeability in PAR-1 knockout mice
    S M Vogel
    Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois 60612, USA
    Physiol Genomics 4:137-145. 2000
    ..The results indicate that the PAR-1 receptor is critical in mediating the permeability-increasing and vasoconstrictor effects of thrombin in pulmonary microvessels...