M Mori

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint Localization of platelet-activating factor receptor messenger RNA in the rat eye
    M Mori
    Department of Ophthalmology, Faculty of Medicine, University of Tokyo, Japan
    Invest Ophthalmol Vis Sci 38:2672-8. 1997
  2. ncbi request reprint The genetic contribution of the TNFa11 microsatellite allele and the TNFb + 252*2 allele in Japanese RA
    F Takeuchi
    Department of Internal Medicine Allergy and Rheumatology, Faculty of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
    Clin Exp Rheumatol 23:494-8. 2005
  3. ncbi request reprint Genetic contribution of the CD14 -159C/T dimorphism in the promoter region in Japanese RA
    F Takeuchi
    Department of Internal Medicine Allergy and Rheumatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Exp Rheumatol 26:337-9. 2008
  4. ncbi request reprint Genetic contribution of the tumour necrosis factor (TNF) B + 252*2/2 genotype, but not the TNFa,b microsatellite alleles, to systemic lupus erythematosus in Japanese patients
    F Takeuchi
    Department of Internal Medicine Allergy and Rheumatology, Faculty of Medicine, University of Tokyo, Hongo, Tokyo, Japan
    Int J Immunogenet 32:173-8. 2005
  5. ncbi request reprint A genetic epidemiological study of spinocerebellar ataxias in Tottori prefecture, Japan
    M Mori
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    Neuroepidemiology 20:144-9. 2001
  6. ncbi request reprint A novel isoform of human fibroblast growth factor 8 is induced by androgens and associated with progression of esophageal carcinoma
    S Tanaka
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Dig Dis Sci 46:1016-21. 2001
  7. ncbi request reprint Spinocerebellar ataxia type 6: founder effect in Western Japan
    M Mori
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, 36 1 Nishimachi, Yonago, Tottori 683 8504, Japan
    J Neurol Sci 185:43-7. 2001
  8. ncbi request reprint Association of CTLA-4 with systemic sclerosis in Japanese patients
    F Takeuchi
    Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Exp Rheumatol 20:823-8. 2002
  9. pmc A dominant negative mutation of transforming growth factor-beta receptor type II gene in microsatellite stable oesophageal carcinoma
    S Tanaka
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Br J Cancer 82:1557-60. 2000
  10. pmc Improvements in diagnosis have changed the incidence of histological types in advanced gastric cancer
    Y Ikeda
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Br J Cancer 72:424-6. 1995

Collaborators

Detail Information

Publications80

  1. ncbi request reprint Localization of platelet-activating factor receptor messenger RNA in the rat eye
    M Mori
    Department of Ophthalmology, Faculty of Medicine, University of Tokyo, Japan
    Invest Ophthalmol Vis Sci 38:2672-8. 1997
    ..To determine the distribution of platelet-activating factor (PAF) receptor in the rat eye...
  2. ncbi request reprint The genetic contribution of the TNFa11 microsatellite allele and the TNFb + 252*2 allele in Japanese RA
    F Takeuchi
    Department of Internal Medicine Allergy and Rheumatology, Faculty of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
    Clin Exp Rheumatol 23:494-8. 2005
    ..The contribution of the microsatellite polymorphisms of TNFa and TNFb, and the TNFB + 252 (TNFB) dimorphism to the pathogenesis of rheumatoid arthritis (RA) was studied among Japanese patients...
  3. ncbi request reprint Genetic contribution of the CD14 -159C/T dimorphism in the promoter region in Japanese RA
    F Takeuchi
    Department of Internal Medicine Allergy and Rheumatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Exp Rheumatol 26:337-9. 2008
    ..To study the contribution of the CD14 gene to the pathogenesis of rheumatoid arthritis (RA) in Japanese patients...
  4. ncbi request reprint Genetic contribution of the tumour necrosis factor (TNF) B + 252*2/2 genotype, but not the TNFa,b microsatellite alleles, to systemic lupus erythematosus in Japanese patients
    F Takeuchi
    Department of Internal Medicine Allergy and Rheumatology, Faculty of Medicine, University of Tokyo, Hongo, Tokyo, Japan
    Int J Immunogenet 32:173-8. 2005
    ..No association was observed between auto-antibodies and TNF. TNFB*2 is a genetic marker for SLE in Japanese patients, while TNFa and TNFb microsatellites are not associated with SLE...
  5. ncbi request reprint A genetic epidemiological study of spinocerebellar ataxias in Tottori prefecture, Japan
    M Mori
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    Neuroepidemiology 20:144-9. 2001
    ..Mutation at SCA6 was also the most common form of sporadic SCA at 11%. Prevalences per 100,000 individuals were as follows: SCA6, 2.40; SCA1, 0.48; DRPLA, 0.32, and SCA3, 0.16...
  6. ncbi request reprint A novel isoform of human fibroblast growth factor 8 is induced by androgens and associated with progression of esophageal carcinoma
    S Tanaka
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Dig Dis Sci 46:1016-21. 2001
    ..001). Our observations suggest that androgenic exposure will induce FGF isoforms in tumor cells, and expression of these growth factors is associated with the prevalence and prognosis of esophageal carcinoma in males...
  7. ncbi request reprint Spinocerebellar ataxia type 6: founder effect in Western Japan
    M Mori
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, 36 1 Nishimachi, Yonago, Tottori 683 8504, Japan
    J Neurol Sci 185:43-7. 2001
    ..The common haplotype of the shared (CAG)(22) repeat found in this study may indicate the meiotic stability of CAG repeats in SCA6 patients...
  8. ncbi request reprint Association of CTLA-4 with systemic sclerosis in Japanese patients
    F Takeuchi
    Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Exp Rheumatol 20:823-8. 2002
    ..The contribution of CTLA-4 alleles to the pathogenesis of systemic sclerosis (SSc) was studied in Japanese patients...
  9. pmc A dominant negative mutation of transforming growth factor-beta receptor type II gene in microsatellite stable oesophageal carcinoma
    S Tanaka
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Br J Cancer 82:1557-60. 2000
    ..This mutation of TGF-beta RII that is not associated with microsatellite instability might make a dominant negative effect on TGF-beta signal transduction in oesophageal carcinoma...
  10. pmc Improvements in diagnosis have changed the incidence of histological types in advanced gastric cancer
    Y Ikeda
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Br J Cancer 72:424-6. 1995
    ..These differences in the trends between early and advanced cancers are probably due to the different degrees of diagnostic accuracy for the early detection of histological types...
  11. ncbi request reprint Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and myocardial infarction in Japanese. An approach entailing melting curve analysis with specific fluorescent hybridization probes
    H Morita
    Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Japan
    Thromb Haemost 85:226-30. 2001
    ....
  12. ncbi request reprint Macrocystic type of serous cystadenoma with a communication between the cyst and pancreatic duct
    M Hashimoto
    Department of Digestive Surgery, Toranomon Hospital, Tokyo, Japan
    J Gastroenterol Hepatol 16:836-8. 2001
    ..This case illustrates the difficulty in the diagnosis of cystic lesions in the pancreas, and might support the single category of cystic lesions of the pancreas...
  13. ncbi request reprint Primary undifferentiated carcinoma arising from the retroperitoneum: a case report
    K Nagasaka
    Department of Obstetrics, Mitsui Memorial Hospital, Tokyo, Japan
    Int J Gynecol Cancer 15:1108-11. 2005
    ..Afterward, a new recurrent tumor appeared along the aorta up to the left supraclavicular node. The patient died 19 months after the first operation...
  14. ncbi request reprint Clinical and genetic epidemiological study of 16q22.1-linked autosomal dominant cerebellar ataxia in western Japan
    M Hayashi
    Department of Neurology, Faculty of Medicine, Institute of Neurological Sciences, Tottori University, Yonago, Japan
    Acta Neurol Scand 116:123-7. 2007
    ..1-linked ADCA showing pure cerebellar ataxia. We screened patients with spinocerebellar degeneration (SCD) to investigate the frequency and clinical features of 16q22.1-linked ADCA...
  15. ncbi request reprint Platelet-activating factor and somatostatin activate mitogen-activated protein kinase (MAP kinase) and arachidonate release
    T Shimizu
    Department of Biochemistry, Faculty of Medicine, University of Tokyo, Japan
    J Lipid Mediat Cell Signal 14:103-8. 1996
    ..Arachidonic acid or its derivatives, thus produced by the activation of these receptors may play some roles in synaptic transmission and synaptic plasticity...
  16. ncbi request reprint Mesenteric panniculitis of the colon. Review of the literature and report of two cases
    Y Adachi
    Second Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Dis Colon Rectum 30:962-6. 1987
    ..Mesenteric panniculitis of the colon seems to be a lesion more advanced than the same condition of the small intestine, and colostomy or bypass surgery may be needed for alleviation of severe symptoms...
  17. ncbi request reprint S100 protein positive human breast carcinomas: an immunohistochemical study
    S Matsushima
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    J Surg Oncol 55:108-13. 1994
    ..NSE, or actin staining. The nature of S100 protein positive carcinoma cells still remains unclear. The S100 protein positive carcinomas, however, exhibit relatively better characteristics...
  18. doi request reprint Pinguecula and contact lenses
    T Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Eye (Lond) 24:1685-91. 2010
    ..To assess the relationship between age and the incidence and severity (determined by a grading system) of pinguecula in contact lens (CL) wearers, and to compare the grade of pinguecula between CL wearers and non-wearers...
  19. ncbi request reprint Energy-dependent export of leukotriene B4 in Xenopus oocytes
    M Mori
    Department of Biochemistry, Faculty of Medicine, University of Tokyo, Japan
    Biochim Biophys Acta 1168:23-9. 1993
    ..It was thus shown that the two potent lipid mediators are exported from cells in a different manner and that oocytes are a good model for analyzing export systems for bioactive mediators...
  20. ncbi request reprint Blind loop syndrome: multiple ileal ulcers following side-to-side anastomosis
    Y Adachi
    Second Department of Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Pathology 25:402-4. 1993
    ..This feature is similar to that of ischemic enteritis. This case further supports the fact that when side-to-side anastomosis is performed as a bypass operation, multiple ulcers may develop in a bypassed loop after a long period of time...
  21. ncbi request reprint Mode of inheritance of HLA-DRB1 shared epitope in Japanese familial rheumatoid arthritis
    F Takeuchi
    Dept of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan
    Clin Exp Rheumatol 20:395-8. 2002
    ..To clarify the mode of genetic contribution of the HLA-DR shared epitope (SE) to the pathogenesis of familial cases of Japanese rheumatoid arthritis (RA)...
  22. pmc Immunohistochemical expression of tenascin in normal stomach tissue, gastric carcinomas and gastric carcinoma in lymph nodes
    Y Ikeda
    Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan
    Br J Cancer 72:189-92. 1995
    ..Tenascin appears during the process of either malignant transformation or tumour progression in gastric cancer, and the positive expression of tenascin may be useful as a stromal marker for the early detection of gastric cancer...
  23. ncbi request reprint p300/CBP acts as a coactivator of the cone-rod homeobox transcription factor
    Y Yanagi
    Department of Ophthalmology, University of Tokyo School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    Biochem Biophys Res Commun 269:410-4. 2000
    ..The C-terminal domain of CRX was mapped as a transactivation domain to associate with p300/CBP. Taken together, our results demonstrate that p300/CBP acts as one of the coactivators of CRX...
  24. pmc A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals
    S Tanaka
    Department of Surgery, Medical Institute of Bioregulation, and Department of Surgery II, Faculty of Medicine, Kyushu University, Japan
    Proc Natl Acad Sci U S A 95:10164-9. 1998
    ..These observations suggest that FzE3 gene expression may down-regulate APC function and enhance beta-catenin mediated signals in poorly differentiated human esophageal carcinomas...
  25. ncbi request reprint Esophageal smooth muscle tumor in a 25-year-old woman with congenital malformations
    H Maekawa
    First Department of Internal Medicine, University of Tokyo, School of Medicine, Japan
    J Gastroenterol 36:700-3. 2001
    ..These congenital malformations cannot be explained by any reported syndromes...
  26. ncbi request reprint Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones
    M Yasue
    Institute of Laboratory Animals, Faculty of Medicine, Kyoto University, Japan
    Genomics 12:659-64. 1992
    ..Syntenic conservation of the genes among rats, mice, and humans is discussed...
  27. ncbi request reprint Isolation of cDNA clones of human argininosuccinate lyase and corrected amino acid sequence
    S Matuo
    Department of Biochemistry, Faculty of Medicine, Kagoshima Univeristy, Japan
    FEBS Lett 234:395-9. 1988
    ..Amino acid sequencing of peptides prepared from purified human liver ASL showed our predicted amino acid sequence to be correct...
  28. ncbi request reprint Chromosome 13 locus, Pbd2, regulates bone density in mice
    M Shimizu
    Department of Orthopedic Surgery, Faculty of Medicine, Kyoto University, Japan
    J Bone Miner Res 16:1972-82. 2001
    ..These results confirmed the existence of a Pbd2 locus regulating bone density in the SAM strains...
  29. ncbi request reprint Localization of the rat insulin I gene (INS1) to chromosome 1q55 by fluorescence in situ hybridization
    M Mori
    Institute of Laboratory Animals, Faculty of Medicine, Kyoto University, Japan
    Cytogenet Cell Genet 59:31-3. 1992
    ..The rat insulin I gene (INS1) was assigned to chromosome 1q55 using fluorescent in situ hybridization. In addition, several RFLPs were detected among 11 inbred rat strains...
  30. ncbi request reprint Leukotriene A4 hydrolase, a bifunctional enzyme. Distinction of leukotriene A4 hydrolase and aminopeptidase activities by site-directed mutagenesis at Glu-297
    M Minami
    Department of Biochemistry, Faculty of Medicine, University of Tokyo, Japan
    FEBS Lett 309:353-7. 1992
    ..It is thus proposed that either a glutamic or glutamine moiety at 297 is required for full LTA4 hydrolase activity, while the free carboxylic acid of glutamic acid is essential for aminopeptidase...
  31. ncbi request reprint CTLA-4 dimorphisms in Japanese patients with systemic lupus erythematosus
    F Takeuchi
    Clin Exp Rheumatol 21:527-8. 2003
  32. pmc Allelic losses on chromosome 3p are accumulated in relation to morphological changes of lung adenocarcinoma
    H Iijima
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3 39 15 Showa Machi, Maebashi, Gunma 371 8511, Japan
    Br J Cancer 91:1143-8. 2004
    ..031 and four out of 12, 33%; P = 0.057). These results indicated that allelic losses at 3p14.2 and telomeric region of 3p21.3 are related to pattern of the proliferation of lung adenocarcinoma...
  33. ncbi request reprint Genetic polymorphism of N-acetyltransferase 2 in patients with esophageal cancer
    J Shibuta
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Am J Gastroenterol 96:3419-24. 2001
    ..However, there remains a controversy and no consensus concerning whether there is a true association between esophageal cancer and N-acetylation polymorphism...
  34. ncbi request reprint [Behavior of drinking alcoholic beverages among junior and senior high school students in the area covered with Wakkanai Health Center of Hokkaido, Japan]
    K Takeida
    Hokkaido Wakkanai Public Health Center, 4-2-27 Suehiro, Wakkanai-City, Hokkaido 097-8558, Japan
    Nihon Arukoru Yakubutsu Igakkai Zasshi 36:491-503. 2001
    ..We think that it is indispensable to communicate or educate harmfulness of drinking during adolescence for students as well as for their parents, especially, in this area...
  35. ncbi request reprint Deletion mapping of chromosome 2 in human lung carcinoma
    T Otsuka
    Biology Division, National Cancer Center Research Institute, Tokyo, Japan
    Genes Chromosomes Cancer 16:113-9. 1996
    ..046). These results suggested that inactivation of tumor suppressor genes on chromosome 2 is involved in the phenotypic alterations of NSCLC cells into more aggressive ones...
  36. ncbi request reprint The genetic contribution of CTLA-4 dimorphisms in promoter and exon 1 regions in Japanese patients with rheumatoid arthritis
    F Takeuchi
    Scand J Rheumatol 35:154-5. 2006
  37. ncbi request reprint Intrapericardial instillation of mitomycin C in recurrent cardiac tamponade due to malignant pericardial effusion
    K Kaira
    Clin Oncol (R Coll Radiol) 18:506. 2006
  38. ncbi request reprint Depression among caregivers of the frail elderly in Japan before and after the introduction of the Public Long-Term Care Insurance System
    A Oura
    Department of Public Health, School of Medicine, Sapporo Medical University, Sapporo, Hokkaido, 060 8556, Japan
    Z Gerontol Geriatr 40:112-8. 2007
    ..Even after the introduction of LTCIS, half of the caregivers were depressive. It is suggested that a government agency should be created to support not only the frail elderly but also their caregivers...
  39. ncbi request reprint Association between reflux oesophagitis and features of the metabolic syndrome in Japan
    F Moki
    Gunma Health Foundation, Maebashi, Japan
    Aliment Pharmacol Ther 26:1069-75. 2007
    ..There have been many reports about the relationship between reflux oesophagitis and obesity, but not the metabolic syndrome...
  40. doi request reprint Age-stratified serum levels of isoflavones and proportion of equol producers in Japanese and Korean healthy men
    K Fujimoto
    Department of Urology, Nara Medical University, Kashihara, Japan
    Prostate Cancer Prostatic Dis 11:252-7. 2008
    ..Elucidating the mechanism of equol production may be promising in developing strategies for chemoprevention against prostate cancer...
  41. ncbi request reprint Granulomas in hepatocellular carcinoma induced by lipiodolized SMANCS, a polymer-conjugated derivative of neocarzinostatin
    T Ichikawa
    Histopathology 40:579-80. 2002
  42. ncbi request reprint A comparison of body perceptions in relation to measured body composition in young Japanese males and females
    M Kagawa
    School of Public Health, Curtin University of Technology, Australia
    Body Image 4:372-80. 2007
    ..The results confirmed distinct gender differences in body perception in relation to actual body composition and attitudes to weight management. Further promotion of "healthy" body image is recommended for the Japanese population...
  43. ncbi request reprint Characterization of 'adult-type' mast cells derived from human bone marrow CD34(+) cells cultured in the presence of stem cell factor and interleukin-6. Interleukin-4 is not required for constitutive expression of CD54, Fc epsilon RI alpha and chymase, an
    Y Shimizu
    Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Clin Exp Allergy 32:872-80. 2002
    ..In vitro-derived human mast cells exhibit different properties, depending in part on the source of progenitor cells. Most investigations have used fetal liver, cord blood or peripheral blood. Few have used adult bone marrow...
  44. ncbi request reprint Expectoration of bronchogenic tumour tissue
    K Kaira
    Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Intern Med J 37:340-2. 2007
  45. ncbi request reprint Allelic imbalance and microsatellite instability in plasma DNA released from polyclonal pancreatic adenocarcinoma
    H Moriyama
    Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Int J Oncol 21:949-56. 2002
    ..Analysis of plasma DNA could become one of the diagnostic or therapeutic measures for this type of pancreatic adenocarcinoma...
  46. ncbi request reprint High frequency of mutations in the HNF-1alpha gene in non-obese patients with diabetes of youth in Japanese and identification of a case of digenic inheritance
    N Tonooka
    First Department of Internal Medicine, Gunma University, Japan
    Diabetologia 45:1709-12. 2002
    ..Since approximately 20% of Caucasian patients with HNF-1alpha mutations have been shown to be obese or overweight, we also examined the association of genetic variations in TCF1 with body weight in Japanese subjects...
  47. pmc Identification of the high-risk group for metastasis of gastric cancer cases by vascular endothelial growth factor receptor-1 overexpression in peripheral blood
    Y Kosaka
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, 4546, Tsurumihara, Beppu 874 0838, Japan
    Br J Cancer 96:1723-8. 2007
    ..Our data suggest that the amount of positive cells may provide information on the clinical features of gastric cancer, especially in regard to gastric cancer metastasis...
  48. ncbi request reprint Sodium channels SCN1A, SCN2A and SCN3A in familial autism
    L A Weiss
    Department of Human Genetics, University of Michigan, 4708 Medical Science II, Ann Arbor, MI 48109 0618, USA
    Mol Psychiatry 8:186-94. 2003
    ..SNP density was 1/kb in the genomic sequence screened. We report 38 sodium channel SNPs that will be useful in future association and linkage studies...
  49. ncbi request reprint Identification of EGFR mutations in esophageal cancer
    T Sudo
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumihara, Beppu 874 0838, Japan
    Eur J Surg Oncol 33:44-8. 2007
    ....
  50. pmc Molecular cloning and nucleotide sequence of cDNA for human liver arginase
    Y Haraguchi
    Proc Natl Acad Sci U S A 84:412-5. 1987
    ..The predicted amino acid sequence of human liver arginase is 87% and 41% identical with those of the rat liver and yeast enzymes, respectively. There are several highly conserved segments among the human, rat, and yeast enzymes...
  51. ncbi request reprint Does Campylobacter jejuni infection elicit "demyelinating" Guillain-Barre syndrome?
    S Kuwabara
    Department of Neurology, Chiba University School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba, 260 8670, Japan
    Neurology 63:529-33. 2004
    ..C. jejuni-related GBS is usually acute motor axonal neuropathy (AMAN), but previous reports described many cases of the demyelinating subtype of GBS (acute inflammatory demyelinating polyneuropathy [AIDP]) after C. jejuni infection...
  52. ncbi request reprint Mapping QTLs for grain dormancy on wheat chromosome 3A and the group 4 chromosomes, and their combined effect
    M Mori
    Department of Crop Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, 080 8555, Hokkaido, Japan
    Theor Appl Genet 110:1315-23. 2005
    ..ocs-3A.1 and QPhs.ocs-4A.1 and the CS allele at QPhs.ocs-4B1. This demonstrated a combined effect of the desirable alleles on accelerating grain dormancy, with their total effect being superior to that of Zen...
  53. pmc A ligand for peroxisome proliferator activated receptor gamma inhibits cell growth and induces apoptosis in human liver cancer cells
    M Toyoda
    First Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Gunma, Japan
    Gut 50:563-7. 2002
    ..Recently, one of the NHRs, peroxisome proliferator activated receptor gamma (PPARgamma), has been shown to influence cell growth in certain cancer cells although its effect on hepatocellular carcinoma (HCC) has not been analysed...
  54. pmc Distribution patterns of demyelination correlate with clinical profiles in chronic inflammatory demyelinating polyneuropathy
    S Kuwabara
    Department of Neurology, Chiba University School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    J Neurol Neurosurg Psychiatry 72:37-42. 2002
    ....
  55. ncbi request reprint Raised plasma concentrations of parathyroid hormone related peptide in hypercalcemic multiple myeloma
    T Horiuchi
    Section of Endocrinology, Tokyo Metropolitan Geriatric Hospital, Japan
    Horm Metab Res 29:469-71. 1997
    ..Therefore, further studies are necessary to elucidate the pathogenesis of hypercalcemia in multiple myeloma...
  56. ncbi request reprint The murine DNA-PKcs gene consists of 86 exons dispersed in more than 250 kb
    A Fujimori
    Division of Biology and Oncology, National Institute of Radiological Sciences, Chiba, Japan
    Genomics 45:194-9. 1997
    ..The SCID mutation site (Tyr4046) has been identified in exon 85. The genomic structure of the DNA-PKcs gene provides clues for the study of various functional domains in this macromolecule...
  57. ncbi request reprint [Analysis of children with tuberculosis in the past 20 years]
    M Ibe
    Department of Pediatrics, Yokohama City University School of Medicine
    Kansenshogaku Zasshi 71:513-21. 1997
    ....
  58. ncbi request reprint Cloning of the mouse hypothalamic preprothyrotropin-releasing hormone (TRH) cDNA and tissue distribution of its mRNA
    T Satoh
    First Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Brain Res Mol Brain Res 14:131-5. 1992
    ..Moreover, it was noteworthy to find that the degree of homology to the region containing the sixth TRH-coding sequence of the human preproTRH was higher in the mouse preproTRH than the rat counterpart.(ABSTRACT TRUNCATED AT 250 WORDS)..
  59. ncbi request reprint Genomic organization and promoter function of the human thyrotropin-releasing hormone receptor gene
    T Iwasaki
    First Department of Internal Medicine, Gunma University School of Medicine, Maebashi 371 Japan
    J Biol Chem 271:22183-8. 1996
    ....
  60. ncbi request reprint Pituitary adenomas of patients with acromegaly express thyrotropin-releasing hormone receptor messenger RNA: cloning and functional expression of the human thyrotropin-releasing hormone receptor gene
    M Yamada
    First Department of Internal Medicine, Gunma University School of Medicine, Japan
    Biochem Biophys Res Commun 195:737-45. 1993
    ....
  61. ncbi request reprint [Analysis of children with tuberculosis in recent 10 years]
    M Mori
    Department of Pediatrics, Yokohama City University School of Medicine
    Kansenshogaku Zasshi 68:887-93. 1994
    ..Thus, in children with tuberculosis the detection of serum IgM levels as well as family history, tuberculin reaction, and chest X-ray findings may be helpful for the early diagnosis and prompt decision of hospitalization...
  62. ncbi request reprint Assignment of CD38, the gene encoding human leukocyte antigen CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase), to chromosome 4p15
    K Nakagawara
    Department of Biochemistry, Tohoku University School of Medicine, Miyagi, Japan
    Cytogenet Cell Genet 69:38-9. 1995
    ..We have mapped the CD38 gene to human chromosome 4p15 by fluorescence in situ hybridization...
  63. pmc cDNA-derived amino acid sequence of rat mitochondrial 3-oxoacyl-CoA thiolase with no transient presequence: structural relationship with peroxisomal isozyme
    H Arakawa
    EMBO J 6:1361-6. 1987
    ..Two portions in the mitochondrial thiolase that may serve as a mitochondrial targeting signal are presented...
  64. pmc Molecular basis of argininemia. Identification of two discrete frame-shift deletions in the liver-type arginase gene
    Y Haraguchi
    Department of Pediatrics, Kumamoto University Medical School, Japan
    J Clin Invest 86:347-50. 1990
    ..These data seem to be the first evidence of a case of argininemia caused by two different deletion mutations...
  65. ncbi request reprint [Prevalence of the antibody against human polyoma viruses (JCV and BKV) in aged persons]
    M Tajima
    Division of Virology, Teikyo University School of Medicine
    Kansenshogaku Zasshi 64:1507-13. 1990
    ..4) The average antibody titers of HSV and CMV, tended to increase as the age advanced until 60 and to decrease with age over 70. These results indicate that JCV is reactivated in a high rate in the aged (70 less than) persons...
  66. ncbi request reprint Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer
    K Shibata
    Department of Surgery, Kyushu University, Beppu, Japan
    Biochem Biophys Res Commun 246:205-9. 1998
    ..The findings demonstrated that the reduced or suppressed expression of human G-protein gamma 7 may play an important role in pancreatic carcinogenesis...
  67. ncbi request reprint Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor
    M Mori
    Discovery Research Laboratories I, Pharmaceutical Research Division, Takeda Chemical Industries, Ltd, Wadai 10, Tsukuba, Ibaraki, 300 4293, Japan
    Biochem Biophys Res Commun 283:1013-8. 2001
    ..The distribution of the SLT nearly overlapped that of SLC-1, suggesting that some of the neural functions of MCH may be mediated by both of these receptor subtypes...
  68. ncbi request reprint Spontaneous loss-of-function mutations of the 8-oxoguanine DNA glycosylase gene in mice and exploration of the possible implication of the gene in senescence
    M Mori
    Department of Aging Angiology, Research Center on Aging and Adaptation, Shinshu University School of Medicine, Matsumoto, Japan
    Free Radic Biol Med 30:1130-6. 2001
    ..Mutant OGG1 may be associated with pathologic conditions in other mouse strains...
  69. ncbi request reprint Molecular characterization of ionizing radiation-hypersensitive mutant M10 cells
    M Mori
    Radiation Hazard Research Group, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba 263 8555, Japan
    Mutat Res 487:85-92. 2001
    ..Transfection of M10 cells with the murine Xrcc4 cDNA completely rescued X-ray sensitivity of the mutant cells. M10 is a novel Xrcc4-deficient cell line...
  70. ncbi request reprint CAM-cytarabine, aclarubicin plus macrophage colony-stimulating factor in the treatment of acute myelogenous leukemia with trilineage dysplasia: usefulness of in vitro apoptosis in leukemic cells
    M Mori
    Department of Hematology, Jichi Medical School, 3311-1 Yakushiji, Minamikawachi, Kawachi, Tochigi 329-0498, Japan
    Leuk Lymphoma 42:387-91. 2001
    ..This case confirms an earlier report that an effect of M-CSF inducible by differentiation with apoptotic phenomena, against human leukemic cells was shown both in vitro and in vivo when achieving complete remission...
  71. ncbi request reprint Transforming growth factor beta and activin tonically inhibit DNA synthesis in the rat liver
    T Ichikawa
    First Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan
    Hepatology 34:918-25. 2001
    ..TGF-beta and activin tonically inhibit hepatocyte growth even in intact liver and may play a critical role in the maintenance of constant liver mass...
  72. ncbi request reprint Brain natriuretic polypeptide in type 2 NIDDM patients with albuminuria
    T Nagai
    The Department of Internal Medicine, Public Tomioka General Hospital, Gunma, Japan
    J Med 32:169-80. 2001
    ..Elevated plasm BNP may play a pathophysiological role in the development of diabetic nephropathy...
  73. ncbi request reprint Unique mutations in mitochondrial DNA of senescence-accelerated mouse (SAM) strains
    J Mizutani
    Department of Aging Angiology, Research Center on Aging and Adaptation, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan
    J Hered 92:352-5. 2001
    ..The polymorphism in mtDNA could be used to ascertain the genealogy of other mouse strains as well...
  74. ncbi request reprint [Tuberculosis of the elderly (above the age of 75) in national hospitals]
    M Mori
    National Tokyo Hospital
    Kekkaku 76:533-43. 2001
    ..Because tuberculosis, once the disease of the young, is becoming rapidly the disease of the elderly, it is imperative for us to make necessary adjustments to meet this inevitable trend...
  75. ncbi request reprint Quantitative trait loci for body weight in the intercross between SM/J and A/J mice
    R V Anunciado
    Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8601, Japan
    Exp Anim 50:319-24. 2001
    ..These suggestive QTLs explained 5-6% of the phenotypic variance and all the SM/J alleles decreased body weight...
  76. pmc Cytokeratins 8 and 19 in the mouse placental development
    Y Tamai
    Banyu Tsukuba Research Institute Merck, Tsukuba, Ibaraki 300 2611, Japan
    J Cell Biol 151:563-72. 2000
    ..These results indicate that K19 and K8 cooperate in ensuring the normal development of placental tissues...
  77. ncbi request reprint Identification of myelodysplastic syndrome-specific genes by DNA microarray analysis with purified hematopoietic stem cell fraction
    A Miyazato
    Divisions of Functional Genomics, Hematology, Cardiology, and Molecular Immunology, Jichi Medical School, Kawachi-gun, Tochigi, Japan
    Blood 98:422-7. 2001
    ..The proposal is made that microarray analysis with the Blast Bank samples is an efficient approach to extract transcriptome data of clinical relevance for a wide range of hematologic disorders...
  78. ncbi request reprint Co-induction of argininosuccinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells
    K Kawahara
    Department of Biofunctional Chemistry, Faculty of Pharmaceutical Sciences, Kumamoto University, 5-1 Ohe-Honmachi, 862-0973, Kumamoto, Japan
    Brain Res Mol Brain Res 90:165-73. 2001
    ..These results strongly suggest that both arginine transport by CAT-2 and citrulline-arginine recycling are important for high-output production of NO in activated microglial cells...
  79. ncbi request reprint Mutational analysis of the BMP-1 gene in patients with gastroschisis
    H Komuro
    Department of Surgery, Jichi Medical School, Tochigi, Japan
    J Pediatr Surg 36:885-7. 2001
    ..CONCLUSION: Although heterogeneous etiologies might be proposed for gastroschisis, our results provide further evidence of a nongenetic etiology for gastroschisis. J Pediatr Surg 36:885-887...
  80. pmc Three novel mutations in the liver-type arginase gene in three unrelated Japanese patients with argininemia
    T Uchino
    Department of Pediatrics, Kumamoto University School of Medicine, Japan
    Am J Hum Genet 51:1406-12. 1992
    ..There was no evidence of activity of the three mutant arginases expressed in E. coli. We tentatively conclude that argininemia is heterogeneous, at the molecular level...