Takeo Minematsu

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. doi request reprint Aging enhances maceration-induced ultrastructural alteration of the epidermis and impairment of skin barrier function
    Takeo Minematsu
    Department of Advanced Skin Care, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Dermatol Sci 62:160-8. 2011
  2. pmc The dual origin of the peripheral olfactory system: placode and neural crest
    Hiroyuki Katoh
    Department of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
    Mol Brain 4:34. 2011
  3. doi request reprint Aging-like skin changes in metabolic syndrome model mice are mediated by mineralocorticoid receptor signaling
    Takashi Nagase
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, 113 0033, Japan
    Aging Cell 12:50-7. 2013
  4. doi request reprint Novel models for bacterial colonization and infection of full-thickness wounds in rats
    Mayumi Asada
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Wound Repair Regen 20:601-10. 2012
  5. doi request reprint Novel biomarkers for the detection of wound infection by wound fluid RT-PCR in rats
    Mayumi Asada
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    Exp Dermatol 21:118-22. 2012
  6. doi request reprint Altered expression of matrix metalloproteinases and their tissue inhibitors in matured rat adipocytes in vitro
    Takeo Minematsu
    Department of Advanced Skin Care, The University of Tokyo, Tokyo, Japan
    Biol Res Nurs 14:242-9. 2012
  7. doi request reprint Impaired aquaporin 3 expression in reepithelialization of cutaneous wound healing in the diabetic rat
    Takashi Sugimoto
    Department of Gerontological Nursing Wound Care Management, Division of Health Science and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Biol Res Nurs 15:347-55. 2013
  8. doi request reprint Vibration inhibits deterioration in rat deep-tissue injury through HIF1-MMP axis
    Yunita Sari
    Department of Gerontological Nursing Wound Care Management, The University of Tokyo, Tokyo, Japan
    Wound Repair Regen 23:386-93. 2015
  9. doi request reprint Establishment of a novel rat model for deep tissue injury deterioration
    Yunita Sari
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Department of Nursing, Jenderal Soedirman University, Purwokerto, Indonesia
    Int Wound J 12:202-9. 2015
  10. doi request reprint Aging-like skin changes induced by ultraviolet irradiation in an animal model of metabolic syndrome
    Tomoko Akase
    Department of Gerontological Nursing Wound Care Management, Division of Health Science and Nursing, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Biol Res Nurs 14:180-7. 2012

Collaborators

Detail Information

Publications29

  1. doi request reprint Aging enhances maceration-induced ultrastructural alteration of the epidermis and impairment of skin barrier function
    Takeo Minematsu
    Department of Advanced Skin Care, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Dermatol Sci 62:160-8. 2011
    ..In health care settings, incontinence-associated skin maceration is highly prevalent in the elderly. However, the effect of senescence on maceration has not been fully elucidated...
  2. pmc The dual origin of the peripheral olfactory system: placode and neural crest
    Hiroyuki Katoh
    Department of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
    Mol Brain 4:34. 2011
    ....
  3. doi request reprint Aging-like skin changes in metabolic syndrome model mice are mediated by mineralocorticoid receptor signaling
    Takashi Nagase
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, 113 0033, Japan
    Aging Cell 12:50-7. 2013
    ..Our studies suggested an unexpected role of MR signaling in the skin aging in MetS status...
  4. doi request reprint Novel models for bacterial colonization and infection of full-thickness wounds in rats
    Mayumi Asada
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Wound Repair Regen 20:601-10. 2012
    ..Wounds were made 2 cm cranial to the greater trochanter. These clinically relevant and highly reproducible animal models can be used to investigate the mechanisms of wound infection and monitor the effect of therapeutic agents in vivo...
  5. doi request reprint Novel biomarkers for the detection of wound infection by wound fluid RT-PCR in rats
    Mayumi Asada
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    Exp Dermatol 21:118-22. 2012
    ..We anticipate that wound fluid RT-PCR could be applied in the future to diagnose wound infection...
  6. doi request reprint Altered expression of matrix metalloproteinases and their tissue inhibitors in matured rat adipocytes in vitro
    Takeo Minematsu
    Department of Advanced Skin Care, The University of Tokyo, Tokyo, Japan
    Biol Res Nurs 14:242-9. 2012
    ..Further studies to determine the effect of other obesity-related factors, such as insulin resistance, on MMPs and TIMPs are required...
  7. doi request reprint Impaired aquaporin 3 expression in reepithelialization of cutaneous wound healing in the diabetic rat
    Takashi Sugimoto
    Department of Gerontological Nursing Wound Care Management, Division of Health Science and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Biol Res Nurs 15:347-55. 2013
    ..In summary, these findings suggest that there may be a relationship between impaired AQP3 expression and diabetes-delayed reepithelialization. Thus, future nursing studies should focus on this mechanism in diabetic wound healing...
  8. doi request reprint Vibration inhibits deterioration in rat deep-tissue injury through HIF1-MMP axis
    Yunita Sari
    Department of Gerontological Nursing Wound Care Management, The University of Tokyo, Tokyo, Japan
    Wound Repair Regen 23:386-93. 2015
    ..These results suggest that vibration therapy can effectively attenuate deterioration of DTI. This report provides the first evidence for a therapeutic treatment for deteriorating DTI. ..
  9. doi request reprint Establishment of a novel rat model for deep tissue injury deterioration
    Yunita Sari
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Department of Nursing, Jenderal Soedirman University, Purwokerto, Indonesia
    Int Wound J 12:202-9. 2015
    ..This model will allow a better understanding of the mechanisms behind DTI deterioration and the development of preventative strategies. ..
  10. doi request reprint Aging-like skin changes induced by ultraviolet irradiation in an animal model of metabolic syndrome
    Tomoko Akase
    Department of Gerontological Nursing Wound Care Management, Division of Health Science and Nursing, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Biol Res Nurs 14:180-7. 2012
    ..These results suggest that UV-irradiated TSOD mice may provide a new model of skin aging and imply that skin from humans with MS is more susceptible to UV- or aging-related damage than normal human skin...
  11. doi request reprint Prediction of healing progress of pressure ulcers by distribution analysis of protein markers on necrotic tissue: A retrospective cohort study
    Aya Kitamura
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Wound Repair Regen 23:772-7. 2015
    ..087). There was no significant relationship between liquefaction and other markers. Peroxidase positivity predicts 1-week liquefaction of necrotic tissue, while a heterogeneous pattern indicates nonliquefaction. ..
  12. doi request reprint Pseudomonas aeruginosa quorum-sensing signaling molecule N-3-oxododecanoyl homoserine lactone induces matrix metalloproteinase 9 expression via the AP1 pathway in rat fibroblasts
    Gojiro Nakagami
    a Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Biosci Biotechnol Biochem 79:1719-24. 2015
    ..These results suggest that 3OC12-HSL can alter MMP9 gene expression in fibroblasts via the AP-1 signaling pathway. ..
  13. pmc Histopathology of Incontinence-Associated Skin Lesions: Inner Tissue Damage Due to Invasion of Proteolytic Enzymes and Bacteria in Macerated Rat Skin
    Yuko Mugita
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan
    PLoS ONE 10:e0138117. 2015
    ..The healing process of this lesion is similar to transepidermal elimination. ..
  14. doi request reprint Wound blotting: a convenient biochemical assessment tool for protein components in exudate of chronic wounds
    Takeo Minematsu
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Wound Repair Regen 21:329-34. 2013
    ..Our results indicate that wound blotting is a convenient method for biochemical analysis of exudate and a candidate tool with which to predict the healing/deterioration of chronic ulcers...
  15. doi request reprint The Pseudomonas aeruginosa quorum sensing signal molecule N-(3-oxododecanoyl) homoserine lactone enhances keratinocyte migration and induces Mmp13 gene expression in vitro
    Camila Paes
    University of Tokyo, Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, 7 3 1 Hongo, Tokyo 113 0033, Japan
    Biochem Biophys Res Commun 427:273-9. 2012
    ..Further investigation is needed to clarify the mechanism of action and molecular pathway of AHL on the keratinocyte migration process...
  16. doi request reprint Compression-induced HIF-1 enhances thrombosis and PAI-1 expression in mouse skin
    Maki Kaneko
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Wound Repair Regen 23:657-63. 2015
    ..These findings may suggest new strategies in pressure ulcer management. ..
  17. pmc Biological responses of three-dimensional cultured fibroblasts by sustained compressive loading include apoptosis and survival activity
    Toshiki Kanazawa
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    PLoS ONE 9:e104676. 2014
    ..These observations support that HSP90α, HA, and, PGE2 could be potential molecular markers for prediction of delayed wound healing due to pressure. ..
  18. pmc Hydrocellular foam dressing promotes wound healing along with increases in hyaluronan synthase 3 and PPARα gene expression in epidermis
    Takumi Yamane
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    PLoS ONE 8:e73988. 2013
    ..This study was aimed to reveal the effect of hydrocellular foam dressing on hyaluronan, which has been shown to have positive effects on wound healing, and examined its regulatory mechanisms in rat skin...
  19. doi request reprint Candidate biomarkers for deep tissue damage from molecular biological and biochemical aspects
    Takeo Minematsu
    Department of Advanced Skin Care, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Tissue Viability 19:77-83. 2010
    ..Our results using PU model rats suggested that exudate CPK could be a more sensitive biomarker than serum CPK for deep muscle tissue injury, and could be applicable for clinical diagnosis of DTI...
  20. doi request reprint Exploring the prevalence of skin tears and skin properties related to skin tears in elderly patients at a long-term medical facility in Japan
    Yuiko Koyano
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Int Wound J 13:189-97. 2016
    ....
  21. doi request reprint Hydrocellular foam dressings promote wound healing associated with decrease in inflammation in rat periwound skin and granulation tissue, compared with hydrocolloid dressings
    Takumi Yamane
    a Faculty of Applied Bioscience, Department of Nutritional Science and Food Safety, Tokyo University of Agriculture, Tokyo, Japan
    Biosci Biotechnol Biochem 79:185-9. 2015
    ..These findings suggest that HCF may promote wound healing along with decrease in inflammation by reducing gene expression levels of IL-1β, IL-6, and IL-10...
  22. doi request reprint Skin blotting: a noninvasive technique for evaluating physiological skin status
    Takeo Minematsu
    Takeo Minematsu, PhD, is a Project Lecturer, Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Japan Motoko Horii, MHS, is an Assistant Professor, Faculty of Nursing, Josai International University, Chiba, Japan Makoto Oe, PhD, is a Project Lecturer, Department of Advanced Nursing Technology, Graduate School of Medicine, The University of Tokyo Junko Sugama, PhD, is a Professor, Department of Clinical Nursing, Graduate School of Medical Science, Kanazawa University, Ishikawa, Japan Yuko Mugita, MHS, is a Doctoral Student Lijuan Huang, PhD, is a Project Researcher Gojiro Nakagami, PhD, is a Lecturer and Hiromi Sanada, PhD, is a Professor, all at the Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Japan
    Adv Skin Wound Care 27:272-9. 2014
    ..The applicability of this technique was further investigated in a clinical setting...
  23. doi request reprint The Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl) homoserine lactone can accelerate cutaneous wound healing through myofibroblast differentiation in rats
    Gojiro Nakagami
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, Faculty of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    FEMS Immunol Med Microbiol 62:157-63. 2011
    ....
  24. doi request reprint Hypo-osmotic shock-induced subclinical inflammation of skin in a rat model of disrupted skin barrier function
    Chihiro Kishi
    Department of Gerontological Nursing Wound Care Management, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Biol Res Nurs 17:135-41. 2015
    ..These results suggest that hypo-osmotic shock-induced inflammatory reactions promote hypersensitivity to pruritus in skin with disrupted barrier function. ..
  25. doi request reprint Telogen elongation in the hair cycle of ob/ob mice
    Natsumi Tasaki
    a Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Biosci Biotechnol Biochem 80:74-9. 2015
    ..These results suggests that ob/ob mice are a possible model animal for telogen effluvium...
  26. doi request reprint Skin fragility in obese diabetic mice: possible involvement of elevated oxidative stress and upregulation of matrix metalloproteinases
    Ai Ibuki
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Exp Dermatol 21:178-83. 2012
    ..These observations may contribute to novel clinical interventions, such as dietary supplementation with antioxidants or application of skin cream containing antioxidants, which may overcome skin fragility in obese patients with diabetes...
  27. doi request reprint Association Between Components of Exudates and Periwound Moisture-Associated Dermatitis in Breast Cancer Patients With Malignant Fungating Wounds
    Nao Tamai
    Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Biol Res Nurs 18:199-206. 2016
    ..016). Prospective studies are needed to clarify correlations and causal relationships between polyamines and erythema and identify therapeutic targets for preventing the development of MAD. ..
  28. doi request reprint Factors associated with deep foot fissures in diabetic patients: a cross-sectional observational study
    Makoto Oe
    Department of Gerontological Nursing, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Int J Nurs Stud 49:739-46. 2012
    ..However, distinctions between superficial and deep fissures have not been well described, and specific factors involved in their development are generally unknown...
  29. doi request reprint Do nutritional markers in wound fluid reflect pressure ulcer status?
    Shinji Iizaka
    Department of Gerontological Nursing Wound Care Management, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Wound Repair Regen 18:31-7. 2010
    ..61, p=0.028). Our results suggest that these traditional nutritional markers in wound fluid, especially wound fluid/serum ratio may be useful to evaluate local PU status...