Kenji Kondo

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. doi request reprint Age-related changes in cell dynamics of the postnatal mouse olfactory neuroepithelium: cell proliferation, neuronal differentiation, and cell death
    Kenji Kondo
    Department of Otolaryngology Head and Neck Surgery, University of Tokyo Graduate School of Medicine, Tokyo 113 8655, Japan
    J Comp Neurol 518:1962-75. 2010
  2. doi request reprint + - Reconstruction of the intratemporal facial nerve using interposition nerve graft: time course of recovery in facial movement and electrophysiological findings
    Kenji Kondo
    Department of Otorhinolaryngology and Head and Neck Surgery, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Acta Otolaryngol Suppl . 2007
  3. ncbi request reprint Hair cell development in vivo and in vitro: analysis by using a monoclonal antibody specific to hair cells in the chick inner ear
    Kenji Kondo
    Department of Clinical Pathology, Kyorin University School of Medicine, Tokyo 181 8611, Japan
    J Comp Neurol 445:176-98. 2002
  4. doi request reprint Distribution and severity of spontaneous lesions in the neuroepithelium and Bowman's glands in mouse olfactory mucosa: age-related progression
    Kenji Kondo
    Department of Otolaryngology, Head and Neck Surgery, University of Tokyo Graduate School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Cell Tissue Res 335:489-503. 2009
  5. doi request reprint Age-related changes of the regeneration mode in the mouse peripheral olfactory system following olfactotoxic drug methimazole-induced damage
    Keigo Suzukawa
    Department of Otolaryngology Head and Neck Surgery, University of Tokyo Graduate School of Medicine, Tokyo 113 8655, Japan
    J Comp Neurol 519:2154-74. 2011
  6. ncbi request reprint Age-related changes in cell density and the proliferation rate of olfactory ensheathing cells in the lamina propria of postnatal mouse olfactory mucosa
    Kenta Watanabe
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Brain Res 1116:82-92. 2006
  7. doi request reprint Ocular vestibular-evoked myogenic potentials (oVEMPs) require extraocular muscles but not facial or cochlear nerve activity
    Yasuhiro Chihara
    Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, University of Tokyo, Hongo 7 3 1, Bunkyo ku, 113 8655 Tokyo, Japan
    Clin Neurophysiol 120:581-7. 2009
  8. doi request reprint Cigarette Smoke Delays Regeneration of the Olfactory Epithelium in Mice
    Rumi Ueha
    Department of Otolaryngology, The University of Tokyo, 7 3 1 Hongo Bunkyo ku, Tokyo, 113 8655, Japan
    Neurotox Res 30:213-24. 2016
  9. ncbi request reprint Supporting cell proliferation after hair cell injury in mature guinea pig cochlea in vivo
    Tatsuya Yamasoba
    Department of Otolaryngology and Head and Neck Surgery, University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 8655, Japan
    Cell Tissue Res 325:23-31. 2006
  10. doi request reprint Bell's palsy in children: relationship between electroneurography findings and prognosis in comparison with adults
    Shintaro Baba
    Department of Otolaryngology, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    Otol Neurotol 32:1554-8. 2011

Collaborators

Detail Information

Publications54

  1. doi request reprint Age-related changes in cell dynamics of the postnatal mouse olfactory neuroepithelium: cell proliferation, neuronal differentiation, and cell death
    Kenji Kondo
    Department of Otolaryngology Head and Neck Surgery, University of Tokyo Graduate School of Medicine, Tokyo 113 8655, Japan
    J Comp Neurol 518:1962-75. 2010
    ..This observation suggests that the turnover of mature ORNs is slower in the older neuroepithelium compared to the younger neuroepithelium...
  2. doi request reprint + - Reconstruction of the intratemporal facial nerve using interposition nerve graft: time course of recovery in facial movement and electrophysiological findings
    Kenji Kondo
    Department of Otorhinolaryngology and Head and Neck Surgery, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Acta Otolaryngol Suppl . 2007
    ..It would also enable them to obtain informed consent from the patients by preoperatively explaining the predicted outcome of the postoperative facial paralysis...
  3. ncbi request reprint Hair cell development in vivo and in vitro: analysis by using a monoclonal antibody specific to hair cells in the chick inner ear
    Kenji Kondo
    Department of Clinical Pathology, Kyorin University School of Medicine, Tokyo 181 8611, Japan
    J Comp Neurol 445:176-98. 2002
    ..All these results as presented here suggest that the 2A7 monoclonal antibody as a hair cell-specific marker together with the culture system could be a potential tool in analysis of mechanisms underlying hair cell development...
  4. doi request reprint Distribution and severity of spontaneous lesions in the neuroepithelium and Bowman's glands in mouse olfactory mucosa: age-related progression
    Kenji Kondo
    Department of Otolaryngology, Head and Neck Surgery, University of Tokyo Graduate School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Cell Tissue Res 335:489-503. 2009
    ..This information should prove useful in improving the understanding of the pathogenetic mechanisms underlying age-related changes in the peripheral olfactory system...
  5. doi request reprint Age-related changes of the regeneration mode in the mouse peripheral olfactory system following olfactotoxic drug methimazole-induced damage
    Keigo Suzukawa
    Department of Otolaryngology Head and Neck Surgery, University of Tokyo Graduate School of Medicine, Tokyo 113 8655, Japan
    J Comp Neurol 519:2154-74. 2011
    ....
  6. ncbi request reprint Age-related changes in cell density and the proliferation rate of olfactory ensheathing cells in the lamina propria of postnatal mouse olfactory mucosa
    Kenta Watanabe
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Brain Res 1116:82-92. 2006
    ....
  7. doi request reprint Ocular vestibular-evoked myogenic potentials (oVEMPs) require extraocular muscles but not facial or cochlear nerve activity
    Yasuhiro Chihara
    Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, University of Tokyo, Hongo 7 3 1, Bunkyo ku, 113 8655 Tokyo, Japan
    Clin Neurophysiol 120:581-7. 2009
    ..The purpose of the present study was to clarify the origin of oVEMPs by examining these possibilities using clinical findings...
  8. doi request reprint Cigarette Smoke Delays Regeneration of the Olfactory Epithelium in Mice
    Rumi Ueha
    Department of Otolaryngology, The University of Tokyo, 7 3 1 Hongo Bunkyo ku, Tokyo, 113 8655, Japan
    Neurotox Res 30:213-24. 2016
    ..These results suggest that CSS impairs regeneration of ORNs by suppressing the development of immature ORNs from ORN progenitors, at least partly by reducing IGF-1 in the nasal mucosa. ..
  9. ncbi request reprint Supporting cell proliferation after hair cell injury in mature guinea pig cochlea in vivo
    Tatsuya Yamasoba
    Department of Otolaryngology and Head and Neck Surgery, University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 8655, Japan
    Cell Tissue Res 325:23-31. 2006
    ..These findings indicate that Deiters cells in the mature mammalian cochlea maintain a limited competence to re-enter the cell cycle and proliferate after hair cell injury, and that they can survive at least for 1 month...
  10. doi request reprint Bell's palsy in children: relationship between electroneurography findings and prognosis in comparison with adults
    Shintaro Baba
    Department of Otolaryngology, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    Otol Neurotol 32:1554-8. 2011
    ..To investigate the correlation between electroneurography (ENoG) findings and the prognosis of Bell's palsy in children compared with adults...
  11. doi request reprint Recovery of facial movement and facial synkinesis in Bell's palsy patients
    Kaori Kanaya
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Otol Neurotol 30:640-4. 2009
    ..We examined the relationship between the time course of development of facial synkinesis in patients with Bell's palsy and the severity of facial nerve damage...
  12. ncbi request reprint Musashi-1 expression in postnatal mouse olfactory epithelium
    Kenta Watanabe
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Neuroreport 18:641-4. 2007
    ..These findings are consistent with the fact that globose basal cells are proliferating olfactory precursor cells and that their ability to generate new neurons decreases with aging...
  13. doi request reprint Association of the upregulated expression of focal adhesion kinase with poor prognosis and tumor dissemination in hypopharyngeal cancer
    Go Omura
    Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    Head Neck 38:1164-9. 2016
    ..Focal adhesion kinase (FAK) plays an important role in tumor metastasis. The purpose of this study was to evaluate the significance of FAK expression in surgically treated patients with hypopharyngeal cancer...
  14. doi request reprint Expression of IL-33 and its receptor ST2 in chronic rhinosinusitis with nasal polyps
    Shintaro Baba
    Department of Otolaryngology, Faculty of Medicine, The University of Tokyo, Bunkyo ku
    Laryngoscope 124:E115-22. 2014
    ..However, the role of IL-33 and its receptor ST2 in chronic rhinosinusitis remains unclear...
  15. pmc Developmental changes in the responsiveness of rat spiral ganglion neurons to neurotrophic factors in dissociated culture: differential responses for survival, neuritogenesis and neuronal morphology
    Yulian Jin
    Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo ku, Tokyo, Japan
    Cell Tissue Res 351:15-27. 2013
    ..These findings suggest that NT-3, BDNF, LIF and their combinations predominantly support different ontogenetic events at different developmental stages in the innervation of the inner ear...
  16. doi request reprint Denervation of nasal mucosa induced by posterior nasal neurectomy suppresses nasal secretion, not hypersensitivity, in an allergic rhinitis rat model
    Hironobu Nishijima
    Department of Otolaryngology, University of Tokyo, Tokyo, Japan
    Lab Invest 96:981-93. 2016
    ..Posterior nasal neurectomy may be a therapeutic option for the treatment of hyperrhinorrhea, but not allergic rhinitis hypersensitivity. ..
  17. doi request reprint Responsiveness of rat vestibular ganglion neurons to exogenous neurotrophic factors during postnatal development in dissociated cultures
    Yasuhiro Chihara
    Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Brain Res 1408:1-7. 2011
    ..Developmental changes of VGNs in their responsiveness to exogenous neurotrophic factors should be considered in treating or preventing neuronal degeneration caused by peripheral vestibular lesions...
  18. doi request reprint Amblyopia Associated with Congenital Facial Nerve Paralysis
    Hitoshi Iwamura
    Department of Otolaryngology Head and Neck Surgery, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
    ORL J Otorhinolaryngol Relat Spec 78:105-10. 2016
    ....
  19. doi request reprint Transcription factor early growth response 3 is associated with the TGF-β1 expression and the regulatory activity of CD4-positive T cells in vivo
    Shuji Sumitomo
    Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo 113 8655, Japan
    J Immunol 191:2351-9. 2013
    ..Our results suggest that Egr-3 is a transcription factor associated with TGF-β1 expression and in vivo regulatory activity in both mice and humans...
  20. doi request reprint Prediction of the prognosis of Bell's palsy using multivariate analyses
    Munetaka Ushio
    Department of Otolaryngology, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
    Otol Neurotol 29:69-72. 2008
    ..This study aimed to establish more reliable formulae for predicting the prognosis for patients with Bell's palsy at initial examination...
  21. doi request reprint Modified nasal specula and flexible holder for endoscopic nasal surgery
    Munetaka Ushio
    Department of Otolaryngology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Laryngoscope 118:1293-4. 2008
    ..Our modified nasal specula are readily applicable to resolve the problems such as unstable endoscope and narrow working space in septal surgery under endoscopic view...
  22. doi request reprint Sensory deprivation disrupts homeostatic regeneration of newly generated olfactory sensory neurons after injury in adult mice
    Shu Kikuta
    Department of Otolaryngology and Department of Physiology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Neurosci 35:2657-73. 2015
    ..These results indicate that, in the adult OE, sensory deprivation disrupts compensatory OSN regeneration after injury and that newly generated OSNs have a critical time window for sensory-input-dependent survival 7-14 d after injury. ..
  23. ncbi request reprint Correlation between microtia and temporal bone malformation evaluated using grading systems
    Shin Ichi Ishimoto
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Arch Otolaryngol Head Neck Surg 131:326-9. 2005
    ..To evaluate the relationships between temporal bone abnormalities and the severity of microtia in Japanese patients using objective grading systems...
  24. ncbi request reprint Methimazole-induced cell death in rat olfactory receptor neurons occurs via apoptosis triggered through mitochondrial cytochrome c-mediated caspase-3 activation pathway
    Takashi Sakamoto
    Department of Otolaryngology, Mutual Aid Association for Tokyo Metropolitan Teachers and Officials, Sanraku Hospital, Tokyo, Japan
    J Neurosci Res 85:548-57. 2007
    ....
  25. doi request reprint Identification of tonsillar CD4+CD25-LAG3+ T cells as naturally occurring IL-10-producing regulatory T cells in human lymphoid tissue
    Shuji Sumitomo
    Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Autoimmun 76:75-84. 2017
    ..Our study reveals the existence of naturally occurring IL-10-producing Tregs in human secondary lymphoid tissue and their function in immune regulation...
  26. doi request reprint Damage to Olfactory Progenitor Cells Is Involved in Cigarette Smoke-Induced Olfactory Dysfunction in Mice
    Rumi Ueha
    Department of Otolaryngology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Electronic address
    Am J Pathol 186:579-86. 2016
    ....
  27. pmc Current concepts in age-related hearing loss: epidemiology and mechanistic pathways
    Tatsuya Yamasoba
    Department of Otolaryngology and Head and Neck Surgery, University of Tokyo, Tokyo, Japan
    Hear Res 303:30-8. 2013
    ..These may explain the large variations of the onset and extent of AHL among elderly subjects. This article is part of a Special Issue entitled "Annual Reviews 2013". ..
  28. ncbi request reprint Cyclooxygenase-2 regulates the degree of apoptosis by modulating bcl-2 protein in pleomorphic adenoma and mucoepidermoid carcinoma of the parotid gland
    Takashi Sakamoto
    Department of Otorhinolaryngology, Mutual Aid Association for Tokyo Metropolitan Teachers and Officials, Sanraku Hospital, Tokyo, Japan
    Acta Otolaryngol 125:191-5. 2005
    ..These results suggest that COX-2 and bcl-2 protein were overexpressed and that apoptosis was reduced in MEC compared to PMA, and that COX-2 may regulate the degree of apoptosis by modulating bcl-2 protein in PMA and MEC...
  29. ncbi request reprint Overexpression of ErbB-2 protein in human middle ear cholesteatomas
    Takashi Sakamoto
    Department of Otorhinolaryngology, Mutual Aid Association for Tokyo Metropolitan Teachers and Officials, Sanraku Hospital, Tokyo, Japan
    Laryngoscope 114:1988-91. 2004
    ..The purpose of this study is to verify the hypothesis that ErbB-2 protein is overexpressed in human middle ear cholesteatomas and to elucidate the relationship between overexpression of ErbB-2 protein, cell proliferation, and apoptosis...
  30. pmc Innate immune responses and neuroepithelial degeneration and regeneration in the mouse olfactory mucosa induced by intranasal administration of Poly(I:C)
    Kaori Kanaya
    Department of Otolaryngology Head and Neck Surgery, The University of Tokyo Graduate School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    Cell Tissue Res 357:279-99. 2014
    ..These findings suggest that the secondary damage caused by the neutrophil-mediated innate immune response plays an important role in the pathogenesis of PVOD. ..
  31. ncbi request reprint Transgene expression in mature guinea pig cochlear cells in vitro
    Tatsuya Yamasoba
    Department of Otolaryngology, University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 8655, Japan
    Neurosci Lett 335:13-6. 2002
    ..These findings indicate that adenovirus vectors can be transfected into mature guinea pig hair cells and supporting cells in culture...
  32. doi request reprint Age-related change in the axonal diameter of the olfactory nerve in mouse lamina propria
    Kenta Watanabe
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Acta Otolaryngol Suppl . 2007
    ..The present study demonstrated the age-related decrease in the axonal diameter of the olfactory nerve. This finding may represent the maturational change of the olfactory receptor neurons...
  33. ncbi request reprint Temporal bone pathological study on maxillary sinus carcinoma with bilateral temporal bone metastasis
    Peijen Su
    Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine, Graduate School of Medicine, University of Tokyo, Japan
    Acta Otolaryngol 127:1338-44. 2007
    ..Our observations revealed that tumor cells dispersed to the same side through different routes, whereas early metastasis to the contralateral side was mainly through hematogenous and subarachnoid spread...
  34. ncbi request reprint Actions of subtype-specific purinergic ligands on rat spiral ganglion neurons
    Ken Ito
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Acta Otolaryngol Suppl . 2004
    ..These results suggest that, in SGNs, ATP acts via two different receptor subtypes, ionotropic P2Z receptors and metabotropic P2Y receptors, and that these two receptor subtypes can assume different physiological roles...
  35. ncbi request reprint The role of the external auditory canal in the development of the malleal manubrium in humans
    Shin Ichi Ishimoto
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Arch Otolaryngol Head Neck Surg 130:913-6. 2004
    ..To determine if the external auditory canal (EAC) plays a role in the induction and proper positioning of the malleal manubrium in humans...
  36. doi request reprint Establishment of mice expressing EGFP in the placode-derived inner ear sensory cell lineage and FACS-array analysis focused on the regional specificity of the otocyst
    Chisato Fujimoto
    Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Comp Neurol 518:4702-22. 2010
    ....
  37. doi request reprint Facial paralysis after superselective intra-arterial chemotherapy via the middle meningeal artery in maxillary cancer
    Taro Takanami
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo 113 8655, Japan
    Auris Nasus Larynx 36:479-81. 2009
    ..However, in case 2, his facial movement remained at House-Brackmann (H-B) grade IV with severe synkinesis. We must be careful that SSIAC via the MMA may potentially increase the risk of facial paralysis...
  38. pmc Longer latency of sensory response to intravenous odor injection predicts olfactory neural disorder
    Shu Kikuta
    Departments of Otolaryngology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Sci Rep 6:35361. 2016
    ..Moreover, the increase in onset latency correlated with the decrease in mature OSN numbers. Longer onset latency to intravenous odor injection is a useful biomarker for presence and severity of olfactory disorders with neural etiology...
  39. doi request reprint Immunohistochemical study of m1-m5 muscarinic receptors and nNOS in human inferior turbinate mucosa
    Muneo Nakaya
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Acta Otolaryngol Suppl . 2007
    ..This study suggested that nitric oxide (NO) takes part in the parasympathetic nerve control functions mainly through m3 receptors and subsequently through m1 receptors...
  40. doi request reprint Effects of nasal septum perforation repair surgery on three-dimensional airflow: an evaluation using computational fluid dynamics
    Tsutomu Nomura
    Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Eur Arch Otorhinolaryngol 272:3327-33. 2015
    ..Following the surgery, crossflows disappeared, and WS, PG and SSR rate were decreased. A high WS.PG and SSR were suspected as causes of nasal perforation symptoms. ..
  41. doi request reprint Nerve Growth Factor Signals as Possible Pathogenic Biomarkers for Perineural Invasion in Adenoid Cystic Carcinoma
    Kenya Kobayashi
    Department of Otolaryngology, Head and Neck Surgery, The University of Tokyo Hospital, Tokyo, Japan Department of Head and Neck Oncology, National Cancer Center Hospital, Tokyo, Japan
    Otolaryngol Head Neck Surg 153:218-24. 2015
    ..The aim of this study was to examine the expression of NGF together with its receptors, tropomyosin receptor kinase A (TrkA) and p75NRT, and Myb in ACC and assess their relationship with perineural invasion and survival...
  42. doi request reprint Commercially available high-speed system for recording and monitoring vocal fold vibrations
    Sotaro Sekimoto
    Department of Otolaryngology, University of Tokyo, Tokyo, Japan
    Acta Otolaryngol 129:1524-6. 2009
    ..Therefore the system is both cost-effective and useful in the outpatient clinic or casualty setting, on house calls, and for the purpose of student or patient education...
  43. ncbi request reprint Loss of FHIT expression in squamous cell carcinoma and premalignant lesions of the larynx
    Tadashi Yuge
    Department of Otolaryngology, International Medical Center of Japan, Toyama 1 21 1, Shinjuku, Tokyo 162 8655, Japan
    Ann Otol Rhinol Laryngol 114:127-31. 2005
    ..These findings of loss of FHIT protein expression, not only in squamous cell carcinoma, but also in premalignant lesions, indicate that FHIT alterations play an important role in the early events of carcinogenesis...
  44. doi request reprint Complication rates after functional endoscopic sinus surgery: analysis of 50,734 Japanese patients
    Sayaka Suzuki
    Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    Laryngoscope 125:1785-91. 2015
    ..The complication rates associated with different types of functional endoscopic sinus surgery (FESS) remain to be fully examined...
  45. ncbi request reprint Immunohistochemical localization of histamine receptor subtypes in human inferior turbinates
    Muneo Nakaya
    Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Ann Otol Rhinol Laryngol 113:552-7. 2004
    ..This result indicates that H1R, H3R, and H4R adjoin and regulate each other in the same nerves. All histamine receptor subtypes may play some role in patients with allergic rhinitis...
  46. ncbi request reprint Changes in cell proliferation in rat and guinea pig cochlea after aminoglycoside-induced damage
    Tatsuya Yamasoba
    Department of Otolaryngology and Head and Neck Surgery, University of Tokyo, 113 8665, Tokyo, Japan
    Neurosci Lett 347:171-4. 2003
    ..These findings suggest that in the mature mammalian cochlea cell proliferation increases in nonsensory regions after ototoxic damage but may not occur in the auditory sensory epithelium...
  47. ncbi request reprint Neuroendoscopic transnasal surgery for skull base tumors: basic approaches, avoidance of pitfalls, and recent innovations
    Masahiro Shin
    Department of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan
    Neurol Med Chir (Tokyo) 52:697-703. 2012
    ..We believe this article will contribute to the development of safe and effective surgical procedures, and to the benefit of the patients suffering with intractable skull base lesions...
  48. doi request reprint Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles
    Miyuki Baba
    Laboratory of Clinical Biotechnology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Control Release 201:41-8. 2015
    ..These results indicate the feasibility and safety of using mRNA, and provide a novel strategy of mRNA-based therapy. ..
  49. pmc Effects of adacolumn selective leukocytapheresis on plasma cytokines during active disease in patients with active ulcerative colitis
    Hiroyuki Hanai
    Hamamatsu South Hospital, Center for Gastroenterology and IBD Research, Japan
    World J Gastroenterol 12:3393-9. 2006
    ..To investigate the relationship between ulcerative colitis (UC) clinical activity index (CAI) and circulating levels of IL-1ra, IL-10, IL-6 and IL-18...
  50. ncbi request reprint Cholesteatoma of the petrous bone: the crucial role of diffusion-weighted MRI
    Tsuyoshi Yoshida
    Eur Arch Otorhinolaryngol 262:440-1. 2005
  51. ncbi request reprint [A case of gastric GIST treated preoperatively by imatinib mesylate]
    Yoshihiro Hiramatsu
    Second Dept of Surgery, Hamamatsu University School of Medicine
    Gan To Kagaku Ryoho 31:1219-23. 2004
    ..The postoperative course was uneventful and no sign of recurrence was observed 3 months after surgery. Neoadjuvant therapy with IM may become a useful strategy for GIST, as it reduces the tumor size and decreases the recurrence rate...
  52. ncbi request reprint Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information
    Kenji Kondo
    Botanical Raw Materials Research Dept, Tsumura and Co, Ibaraki, Japan
    Biol Pharm Bull 30:1271-7. 2007
    ..However, since 6% of licorice examined and hybrids were exceptions to the rule, their genetic information is necessary for the accurate species identification of licorice...
  53. ncbi request reprint Species identification of licorice using nrDNA and cpDNA genetic markers
    Kenji Kondo
    Botanical Raw Materials Research Department, Tsumura and Co, Ibaraki 300 1192, Japan
    Biol Pharm Bull 30:1497-502. 2007
    ....