University of Tokyo

Summary

Organization: University of Tokyo
Country: Japan

Top Publications

  1. doi What should we do to raise awareness on the issue of cancer in the global health agenda?
    Norie Kawahara
    Research Center for Advanced Science and Technology, The University of Tokyo, 4 6 1 Komaba, Meguro ku, Tokyo, 153 8904, Japan
    Jpn J Clin Oncol 40:i82-85. 2010
  2. doi Modular synthesis of benzo[b]phosphole derivatives via BuLi-mediated cyclization of (o-alkynylphenyl)phosphine
    Hayato Tsuji
    Department of Chemistry, School of Science, The University of Tokyo, Hongo, Tokyo, Japan
    Org Lett 10:2263-5. 2008
  3. ncbi The encoding process of nonconfigural information in contextual cuing
    Hirokazu Ogawa
    Cognitive Science Research Group, Research Center for Advanced Science and Technology, University of Tokyo, Japan
    Percept Psychophys 70:329-36. 2008
  4. ncbi Chemiluminescent-based method for heme determination by reconstitution with horseradish peroxidase apo-enzyme
    Tatsuru Masuda
    Graduate School of Arts and Sciences, University of Tokyo, Komaba, Meguro ku, Tokyo 153 8902, Japan
    Anal Biochem 355:307-9. 2006
  5. pmc Lepidopteran ortholog of Drosophila breathless is a receptor for the baculovirus fibroblast growth factor
    Susumu Katsuma
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    J Virol 80:5474-81. 2006
  6. ncbi Individual variation in feeding habitat use by adult female green sea turtles (Chelonia mydas): are they obligately neritic herbivores?
    Hideo Hatase
    Ocean Research Institute, University of Tokyo, Nakano, Tokyo 164 8639, Japan
    Oecologia 149:52-64. 2006
  7. ncbi Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kappaB and upregulation of BCL-2 and BCL-XL
    T Konishi
    Department of Surgical Oncology, The University of Tokyo, Hongo, Tokyo, Japan
    Oncogene 25:3160-9. 2006
  8. ncbi A novel culture system for porcine odontogenic epithelial cells using a feeder layer
    M J Honda
    Tooth Regeneration, Division of Stem Cell Engineering, The Institute of Medical Science, The University of Tokyo, 4 6 1 Shirokanedai, Tokyo, Japan
    Arch Oral Biol 51:282-90. 2006
  9. ncbi Expression of the floral B-function gene SLM2 in female flowers of Silene latifolia infected with the smut fungus Microbotryum violaceum
    Yusuke Kazama
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, FSB 601, 5 1 5 Kashiwanoha, Kashiwa, Chiba, 277 8562 Japan
    Plant Cell Physiol 46:806-11. 2005
  10. ncbi Computational strategies for analyzing data in gene expression microarray experiments
    Tero Aittokallio
    Department of Computational Biology, University of Tokyo, 5 1 5 Kashiwanoha, Kashiwa shi, Chiba 277 8562, Japan
    J Bioinform Comput Biol 1:541-86. 2003

Scientific Experts

Detail Information

Publications62

  1. doi What should we do to raise awareness on the issue of cancer in the global health agenda?
    Norie Kawahara
    Research Center for Advanced Science and Technology, The University of Tokyo, 4 6 1 Komaba, Meguro ku, Tokyo, 153 8904, Japan
    Jpn J Clin Oncol 40:i82-85. 2010
    ..Based on the challenges and outlook for placing cancer on the global health agenda, we conduct analysis that focuses on top-down mechanisms and bottom-up mechanisms...
  2. doi Modular synthesis of benzo[b]phosphole derivatives via BuLi-mediated cyclization of (o-alkynylphenyl)phosphine
    Hayato Tsuji
    Department of Chemistry, School of Science, The University of Tokyo, Hongo, Tokyo, Japan
    Org Lett 10:2263-5. 2008
    ..An example is given for the synthesis of a bis-benzo[b]phosphole, which can be further converted to the corresponding benzo[b]phosphole oxide possessing high electron affinity...
  3. ncbi The encoding process of nonconfigural information in contextual cuing
    Hirokazu Ogawa
    Cognitive Science Research Group, Research Center for Advanced Science and Technology, University of Tokyo, Japan
    Percept Psychophys 70:329-36. 2008
    ....
  4. ncbi Chemiluminescent-based method for heme determination by reconstitution with horseradish peroxidase apo-enzyme
    Tatsuru Masuda
    Graduate School of Arts and Sciences, University of Tokyo, Komaba, Meguro ku, Tokyo 153 8902, Japan
    Anal Biochem 355:307-9. 2006
  5. pmc Lepidopteran ortholog of Drosophila breathless is a receptor for the baculovirus fibroblast growth factor
    Susumu Katsuma
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    J Virol 80:5474-81. 2006
    ..In these cells, cell motility triggered by vFGF was markedly reduced. These results strongly suggest that the Btl orthologs, BmBtl and SfBtl, are the receptors for vFGF, which mediate vFGF-induced host cell chemotaxis...
  6. ncbi Individual variation in feeding habitat use by adult female green sea turtles (Chelonia mydas): are they obligately neritic herbivores?
    Hideo Hatase
    Ocean Research Institute, University of Tokyo, Nakano, Tokyo 164 8639, Japan
    Oecologia 149:52-64. 2006
    ..These results and previous findings suggest that ontogenetic habitat shifts by sea turtles are facultative, and consequently, their life histories are polymorphic...
  7. ncbi Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kappaB and upregulation of BCL-2 and BCL-XL
    T Konishi
    Department of Surgical Oncology, The University of Tokyo, Hongo, Tokyo, Japan
    Oncogene 25:3160-9. 2006
    ..hRFI might be a novel therapeutic target for gene therapy in colorectal cancer...
  8. ncbi A novel culture system for porcine odontogenic epithelial cells using a feeder layer
    M J Honda
    Tooth Regeneration, Division of Stem Cell Engineering, The Institute of Medical Science, The University of Tokyo, 4 6 1 Shirokanedai, Tokyo, Japan
    Arch Oral Biol 51:282-90. 2006
    ..These results show that the system is capable of sustaining the multiplication of odontogenic epithelial cells with the characteristics of ameloblasts...
  9. ncbi Expression of the floral B-function gene SLM2 in female flowers of Silene latifolia infected with the smut fungus Microbotryum violaceum
    Yusuke Kazama
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, FSB 601, 5 1 5 Kashiwanoha, Kashiwa, Chiba, 277 8562 Japan
    Plant Cell Physiol 46:806-11. 2005
    ..Smut-infected females provide a useful system for clarifying the relationship between the B-function gene and the sex determination factor...
  10. ncbi Computational strategies for analyzing data in gene expression microarray experiments
    Tero Aittokallio
    Department of Computational Biology, University of Tokyo, 5 1 5 Kashiwanoha, Kashiwa shi, Chiba 277 8562, Japan
    J Bioinform Comput Biol 1:541-86. 2003
    ..Solid knowledge of microarray informatics contributes to the implementation of more efficient computational protocols for the given data obtained through microarray experiments...
  11. ncbi Pseudomonas aeruginosa isolated from marine environments in Tokyo Bay
    N Kimata
    Ocean Research Institute, The University of Tokyo, Nakano, Tokyo 164 8639, Japan
    Microb Ecol 47:41-7. 2004
    ..The results confirmed that the majority of isolates from the bay were P. aeruginosa. Immuno-chemical analyses of the seawater results indicate that P. aeruginosa is commonly present in coastal marine environments and sheds OprP...
  12. ncbi Dibasic amino acid residues at the carboxy-terminal end of kinase homology domain participate in the plasma membrane localization and function of phosphatidylinositol 5-kinase gamma
    Manabu Arioka
    Department of Biotechnology, The University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Biochem Biophys Res Commun 319:456-63. 2004
    ....
  13. ncbi Ancestral loss of short wave-sensitive cone visual pigment in lorisiform prosimians, contrasting with its strict conservation in other prosimians
    Shoji Kawamura
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Seimeitou 502, 5 1 5 Kashiwanoha, Kashiwa, Chiba 277 8562, Japan
    J Mol Evol 58:314-21. 2004
    ....
  14. ncbi Influences of age and sex on abdominal muscle and subcutaneous fat thickness
    Hiroaki Kanehisa
    Department of Life Sciences Sports Sciences, University of Tokyo, Komaba 3 8 1, Meguro ku, 153 8902 Tokyo, Japan
    Eur J Appl Physiol 91:534-7. 2004
    ..subcutaneous fat rather than muscle thickness reflected waist circumference, regardless of age and gender...
  15. doi Anthropogenic lead inputs to the western Pacific during the 20th century
    Mayuri Inoue
    Ocean Research Institute, The University of Tokyo, 1 15 1 Minamidai Nakano ku, Tokyo 164 8639, Japan
    Sci Total Environ 406:123-30. 2008
    ....
  16. ncbi In-fiber microchannel device filled with a carbon nanotube dispersion for passive mode-lock lasing
    Amos Martinez
    Department of Electronic Engineering, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8656, Japan
    Opt Express 16:15425-30. 2008
    ..All-fiber high-energy, passive mode-locked lasing is demonstrated with an output power of 13.5 dBm. The key characteristics of the device are compactness and robustness against optical, mechanical and thermal damage...
  17. doi Cyanobacteriochromes: a new superfamily of tetrapyrrole-binding photoreceptors in cyanobacteria
    Masahiko Ikeuchi
    Department of Life Sciences, Biology, The University of Tokyo, Komaba, Meguro, Tokyo, 153 8902, Japan
    Photochem Photobiol Sci 7:1159-67. 2008
    ..We also discussed the functionality of the other candidate GAFs, structure and evolution...
  18. ncbi Development of structured ICD-10 and its application to computer-assisted ICD coding
    Takeshi Imai
    Graduate School of Medicine, The University of Tokyo, Japan
    Stud Health Technol Inform 160:1080-4. 2010
    ..These results not only demonstrate the basic feasibility of our coding framework but might also inform the development of the information model for formal description framework in the ICD11 revision...
  19. doi Relationship between muscle fiber type and tendon properties in young males
    Keitaro Kubo
    Department of Life Science Sports Sciences, University of Tokyo, Komaba 3 8 1, Meguro ku, Tokyo 153 8902, Japan
    Muscle Nerve 42:127-9. 2010
    ..TPT did not correlate significantly with the maximal elongation and stiffness of tendon. In conclusion, we found that the muscle fiber type was not related to the properties of tendons...
  20. doi Correlates of sharing injection equipment among male injecting drug users in Kathmandu, Nepal
    Krishna C Poudel
    Department of Community and Global Health, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Int J Drug Policy 21:507-10. 2010
    ..We explored the correlates of sharing injection equipment (having injected with a needle or syringe previously used by another) among male IDUs in Kathmandu, Nepal...
  21. doi Influence of polymorphism in dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related (DC-SIGNR) gene on HIV-1 trans-infection
    Dayong Zhu
    Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    Biochem Biophys Res Commun 393:598-602. 2010
    ..95). Thus, our results suggest that the variation of the tested DC-SIGNR genotypes affects the efficacy of trans-infection by affecting the amounts of the protein expressed on the cell surface...
  22. doi Permuted tRNA genes in the nuclear and nucleomorph genomes of photosynthetic eukaryotes
    Shinichiro Maruyama
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7 3 1 Hongo, Bunkyo, Tokyo 113 0033, Japan
    Mol Biol Evol 27:1070-6. 2010
    ..Taken together, our data demonstrate that permuted tRNA is an evolutionarily conserved and fundamental element in tiny eukaryotic genomes...
  23. doi Major orthopaedic surgeries for haemophilia with inhibitors using rFVIIa
    H Takedani
    Department of Joint Surgery, Research Hospital of the Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Haemophilia 16:290-5. 2010
    ..In addition, our data also concurs with the data of several previous reports which showed that orthopaedic surgery for haemophilia patients with inhibitors by means of rFVIIa is safe and effective...
  24. doi Subcellular distribution of urea transporter in the collecting tubule of shark kidney is dependent on environmental salinity
    Yoko Yamaguchi
    Laboratory of Physiology, Ocean Research Institute, University of Tokyo, 1 15 1 Minamidai, Nakano, Tokyo 164 8639, Japan
    J Exp Zool A Ecol Genet Physiol 311:705-18. 2009
    ..These results indicate that the accumulation of UT to the apical plasma membrane of the collecting tubule of Triakis is an important factor for regulating urea reabsorption in the kidney...
  25. pmc Inconsistencies of genome annotations in apicomplexan parasites revealed by 5'-end-one-pass and full-length sequences of oligo-capped cDNAs
    Hiroyuki Wakaguri
    Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwanoha, Kashiwa, Chiba, Japan
    BMC Genomics 10:312. 2009
    ..To improve upon the current genome annotations, as well as to validate the importance for physical cDNA clone resources, we generated a large-scale collection of full-length cDNAs for several apicomplexa parasites...
  26. doi Nucleation and growth of aragonite crystals at the growth front of nacres in pearl oyster, Pinctada fucata
    Kazuko Saruwatari
    Department of Earth and Planetary Science, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Biomaterials 30:3028-34. 2009
    ..These results indicate that the crystal growth of aragonite at the growth front results from not only biotic process but also inorganic ones such as geometrical selection and mineral bridges...
  27. pmc Nicastrin is dispensable for gamma-secretase protease activity in the presence of specific presenilin mutations
    Eugene Futai
    Department of Life Sciences, Graduate School of Arts and Sciences, University of Tokyo, Tokyo, Japan
    J Biol Chem 284:13013-22. 2009
    ..These results suggest that NCT is dispensable for the protease activity of gamma-secretase...
  28. doi Properties of cytochrome bd plastoquinol oxidase from the cyanobacterium Synechocystis sp. PCC 6803
    Tatsushi Mogi
    Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    J Biochem 145:395-401. 2009
    ....
  29. doi Regulatory molecules required for nucleotide-sensing Toll-like receptors
    Shin Ichiroh Saitoh
    Division of Infectious Genetics, Institute of Medical Science, University of Tokyo, Tokyo, Japan
    Immunol Rev 227:32-43. 2009
    ..These molecules are potential therapeutic targets for controlling dysregulated TLR7/9 responses in autoimmune diseases...
  30. doi Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice
    Hirotake Ichise
    Laboratory of Gene Expression and Regulation, Center for Experimental Medicine, Institute of Medical Science, University of Tokyo, Tokyo 108 8639, Japan
    Development 136:191-5. 2009
    ..These findings indicate that PLCgamma2 plays an essential role in initiating and maintaining the separation of the blood and lymphatic vasculature...
  31. ncbi CCLS96.1, a member of a multicopy gene family, may encode a non-coding RNA preferentially transcribed in reproductive organs of Silene latifolia
    Ryuji Sugiyama
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7 3 1 Hongo, Bunkyo, Tokyo 113 0033, Japan
    DNA Res 10:213-20. 2003
    ..Genomic Southern hybridization showed that the S. latifolia genome contains numerous CCLS96.1 homologs. These results suggest that the transcripts of CCLS96.1 play some role as multiple non-coding RNAs in S. latifolia...
  32. ncbi Molecular strategies to treat vascular diseases: circulating vascular progenitor cell as a potential target for prophylactic treatment of atherosclerosis
    Masataka Sata
    Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Tokyo and PRESTO, Japan Science and Technology Agency, Kawaguchi
    Circ J 67:983-91. 2003
    ....
  33. ncbi Analysis of dose distribution in gamma knife radiosurgery for multiple targets
    A Terahara
    Department of Radiology, Faculty of Medicine, University of Tokyo, Japan
    Int J Radiat Oncol Biol Phys 47:1431-4. 2000
    ..The aim of this study is to evaluate the actual effect of irradiation for other targets in dose planning for the treatment of multiple metastases with Gamma Knife...
  34. ncbi Adhesion formation can be reduced by the suppression of transforming growth factor-beta1 activity
    N Fukui
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Japan
    J Orthop Res 18:212-9. 2000
    ..Considering the various possible measures to control the activity of the growth factor, suppression of transforming growth factor-beta may be a novel, potent approach to preventing adhesions...
  35. ncbi The p44/42 mitogen-activated protein kinase cascade is involved in the induction and maintenance of astrocyte stellation mediated by protein kinase C
    K Abe
    Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan
    Neurosci Res 36:251-7. 2000
    ..These results suggest that the MEK/ERK cascade is involved in the induction and maintenance of astrocyte stellation mediated by PKC, but not by cyclic AMP signaling...
  36. ncbi Genetic alterations in pediatric medulloblastomas detected by comparative genomic hybridization
    T Nishizaki
    Department of Neurosurgery, Yamaguchi University School of Medicine, Yamaguchi, Japan
    Pediatr Neurosurg 31:27-32. 1999
    ..Our results may indicate that further acquisition of genetic alterations detected by comparative genomic hybridization are associated with unfavorable prognosis in patients with medulloblastomas...
  37. ncbi Pulmonary nodule mimicking lung cancer in a human immunodeficiency virus type-1 infected patient
    T Takahashi
    Department of Infectious Diseases, Institute of Medical Science, University of Tokyo, Japan
    J Med 30:93-9. 1999
    ....
  38. ncbi Cohesin Rec8 is required for reductional chromosome segregation at meiosis
    Y Watanabe
    Cell Cycle Laboratory, Imperial Cancer Research Fund, London, UK
    Nature 400:461-4. 1999
    ..This results in the reductional pattern of chromosome segregation necessary to reduce a diploid zygote to haploid gametes...
  39. ncbi Preparation and application of anti-idiotypic antibody against anti-gibberellin A4 antibody
    Y Suzuki
    Department of Applied Biological Chemistry, University of Tokyo, Japan
    Biosci Biotechnol Biochem 63:648-54. 1999
    ..These results suggest the possible application of anti-idiotypic antibody as a handy and stable source of an enzymatic tracer for ELISA by production of fusion protein of the scFv and an appropriate enzyme...
  40. ncbi Magnetic resonance imaging of acute cerebellar ataxia: report of a case with gadolinium enhancement and review of the literature
    Z Kato
    Department of Pediatrics, Gifu University School of Medicine, Japan
    Acta Paediatr Jpn 40:138-42. 1998
    ..This is the first report of an ACA case with positive gadolinium enhancement. Cases of ACA with MRI abnormalities are reviewed and the clinical entity of ACA is discussed in association with autoimmune encephalitis...
  41. ncbi Formation of lipofuscin-like autofluorescent materials in NG108-15 cells: involvement of lysosomal protein degradation
    Y Mochizuki
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo ku, Japan
    Gerontology 44:1-8. 1998
    ....
  42. ncbi Direct detection of Mycobacterium tuberculosis using polymerase chain reaction assay among patients with hepatic granuloma
    D E Alcantara-Payawal
    Department of Internal Medicine II, Faculty of Medicine, University of Tokyo, Japan
    J Hepatol 27:620-7. 1997
    ....
  43. ncbi Unfused C2C12 mouse skeletal muscle cells express neurofilament 140K protein
    R Matsuda
    Department of Life Sciences, University of Tokyo, Japan
    Cell Struct Funct 22:117-21. 1997
    ..NF140K and desmin double-positive cells were also found in a primary culture of adult mouse skeletal muscle cells. The results suggest that NF140K may be a unique marker for uncommitted myoblasts...
  44. ncbi Ca2+-dependent membrane bound protein fraction from rabbit gastric mucosa contains a protein whose histidyl residue is phosphorylated
    T Urushidani
    Department of Toxicology and Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo, Hongo, Japan
    Biochim Biophys Acta 1356:71-83. 1997
    ..These results suggest that p40 is extramitochondrial alpha subunit of succinyl-CoA synthetase or its homologue...
  45. pmc Linkage-disequilibrium mapping narrows the Fukuyama-type congenital muscular dystrophy (FCMD) candidate region to <100 kb
    T Toda
    Department of Human Genetics, University of Tokyo, Japan
    Am J Hum Genet 59:1313-20. 1996
    ..Thus, the FCMD gene is most likely to lie within a region of <100 kb containing D9S2107...
  46. pmc Multiple signaling pathways in gene expression during sugar starvation. Pharmacological analysis of din gene expression in suspension-cultured cells of Arabidopsis
    Y Fujiki
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo ku, Hongo, Tokyo 113 0033, Japan
    Plant Physiol 124:1139-48. 2000
    ..These results indicate that multiple signaling pathways, mediated by different types of protein phosphatases, regulate gene expression during sugar starvation...
  47. ncbi Redox regulation of the glucocorticoid receptor
    H Tanaka
    Department of Clinical Immunology and AIDS Research Center, Institute of Medical Science, University of Tokyo, Japan
    Antioxid Redox Signal 1:403-23. 1999
    ..Moreover, it is suggested that redox regulation of the receptor function is one of dynamic cellular responses to environmental stimuli and plays an important role in orchestrated crosstalk between central and peripheral stress responses...
  48. ncbi X-ray magnetic circular dichroism imaging with hard X-rays
    K Sato
    Department of Applied Physics, University of Tokyo, Hongo, Bunkyo ku, Tokyo 113 8656, Japan
    J Synchrotron Radiat 8:1021-6. 2001
    ..The observed contrast in the image was reversed by inversion of the magnetic field. Furthermore, the contrast was reversed again at a photon energy of 32 eV above the cobalt K-absorption edge...
  49. ncbi Identification of a novel adrenomedullin gene family in teleost fish
    Maho Ogoshi
    Ocean Research Institute, The University of Tokyo, Nakano, 164 8639, Tokyo, Japan
    Biochem Biophys Res Commun 311:1072-7. 2003
    ..The present study shows for the first time the presence of a novel AM family in teleost fish that is independent from CGRP and amylin, which further suggests the possible existence of multiple AMs in mammals...
  50. ncbi Age-related changes of Alzheimer's disease-associated proteins in cynomolgus monkey brains
    Nobuyuki Kimura
    Department of Biomedical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Biochem Biophys Res Commun 310:303-11. 2003
    ....
  51. ncbi Structural development of synthetic retinoids and thalidomide-related molecules
    Yuichi Hashimoto
    Institute of Molecular and Cellular Biosciences, University of Tokyo, 1 1 1 Yayoi, Bunkyo ku, 113 0032, Tokyo, Japan
    Cancer Chemother Pharmacol 52:S16-23. 2003
    ....
  52. ncbi Impaired liver regeneration after partial hepatectomy in db/db mice
    Hirofumi Yamauchi
    Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan
    Exp Toxicol Pathol 54:281-6. 2003
    ..This suggests that db/db mice may be valuable as one of the animal models for the investigation of the effects of steatosis on the liver regeneration...
  53. ncbi Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    Anesth Analg 96:1386-91, table of contents. 2003
    ..In conclusion, intrathecally administered midazolam and bupivacaine had synergistic analgesic effects on acute thermal- or inflammatory-induced pain, with decreased behavioral side effects...
  54. ncbi Coronary-coronary bypass and pulmonary artery reconstruction related to Wegener granulomatosis in a 22-year-old woman
    Arata Murakami
    Department of Cardiothoracic Surgery, Faculty of Medicine, University of Tokyo, Japan
    J Thorac Cardiovasc Surg 125:721-3. 2003
  55. pmc Analysis of the conformational energy landscape of human snRNA with a metric based on tree representation of RNA structures
    Junji Kitagawa
    Information Science Seminar, Graduate School of Engineering, University of Tokyo, Japan
    Nucleic Acids Res 31:2006-13. 2003
    ..This result reflects different biological functions of these snRNAs in the pre-mRNA splicing process. The results of analyzing tRNAs and rRNAs show that the conformational energy landscapes of these sequences have multi-valley profiles...
  56. ncbi The HAT2 gene, a member of the HD-Zip gene family, isolated as an auxin inducible gene by DNA microarray screening, affects auxin response in Arabidopsis
    Shinichiro Sawa
    Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1, Hongo, Tokyo 113 0033, Japan
    Plant J 32:1011-22. 2002
    ..Together with the results of RNA blotting and biochemical analyses, these findings suggest that HAT2 plays opposite roles in the shoot and root tissues in regulating auxin-mediated morphogenesis...
  57. ncbi Saphenous vein homograft containing a valve as a right ventricle-pulmonary artery conduit in the modified Norwood operation
    Arata Murakami
    Department of Cardiothoracic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Thorac Cardiovasc Surg 124:1041-2. 2002
  58. pmc Analysis of apoptotic and antiapoptotic signalling pathways induced by Helicobacter pylori
    S Maeda
    Department of Gastroenterology, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Gut 50:771-8. 2002
    ..Although it is reported that Helicobacter pylori induces apoptosis on gastric epithelial cells, the mechanism remains unknown. Antiapoptotic effects generated by H pylori have not yet been evaluated...
  59. ncbi Seasonal atopic dermatitis in dogs sensitive to a major allergen of Japanese cedar (Cryptomeria japonica) pollen
    Kenichi Masuda
    Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    Vet Dermatol 13:53-59. 2002
    ..These findings indicated that Cry j 1 was the major allergen recognized by IgE and lymphocytes and resulted in the development of type I hypersensitivity to CJ pollen allergen in these atopic dogs...
  60. ncbi Eradication of poliomyelitis
    Akio Nomoto
    Department of Microbiology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Nat Immunol 3:205-8. 2002
  61. ncbi Differential growth regulation in human melanoma cell lines by TIMP-1 and TIMP-2
    T Hoashi
    Department of Dermatology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Biochem Biophys Res Commun 288:371-9. 2001
    ..The growth of the primary melanoma cell lines was stimulated by TIMP-1 and inhibited by TIMP-2. In contrast, the growth of the visceral metastatic melanoma cell line was stimulated by TIMP-2...
  62. ncbi Isolation, characterization and chromosomal assignment of the human WNT7A gene
    S Ikegawa
    Laboratory of Molecular Medicine, University of Tokyo, Japan
    Cytogenet Cell Genet 74:149-52. 1996
    ..Furthermore, we have isolated a genomic clone of WNT7A and mapped it to chromosome 3p25 by fluorescent in situ hybridization...