H Nakagawa

Summary

Affiliation: Toyama Medical and Pharmaceutical University
Country: Japan

Publications

  1. ncbi request reprint A 16-kDa fragment of collagen type XIV is a novel neutrophil chemotactic factor purified from rat granulation tissue
    H Nakagawa
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Toyama, Sugitani, 930 0194, Japan
    Biochem Biophys Res Commun 256:642-5. 1999
  2. ncbi request reprint Differential production of chemokines and their role in neutrophil infiltration in rat allergic inflammation
    H Nakagawa
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Sugitani, Japan
    Int Arch Allergy Immunol 115:137-43. 1998
  3. ncbi request reprint Cytokine-induced neutrophil chemoattractant (CINC)-2 alpha, a novel member of rat GRO/CINCs, is a predominant chemokine produced by lipopolysaccharide-stimulated rat macrophages in culture
    H Nakagawa
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyoma Medical and Pharmaceutical University, Japan
    Biochem Biophys Res Commun 220:945-8. 1996
  4. ncbi request reprint Identification of a common receptor for three types of rat cytokine-induced neutrophil chemoattractants (CINCs)
    F Shibata
    Department of Physiological Chemistry, Toyama Medical and Pharmaceutical University, Sugitani, Toyama 930 0194, Japan
    Cytokine 12:1368-73. 2000
  5. ncbi request reprint Differential changes in the concentrations of cytokine-induced neutrophil chemoattractant (CINC)-1 and CINC-2 in exudate during rat lipopolysaccharide-induced inflammation
    F Shibata
    Department of Physiological Chemistry, Toyama Medical and Pharmaceutical University, Sugitani, Toyana, Japan
    Cytokine 8:222-6. 1996
  6. ncbi request reprint Contribution of cytokine-induced neutrophil chemoattractant CINC-2 and CINC-3 to neutrophil recruitment in lipopolysaccharide-induced inflammation in rats
    K Takano
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Inflamm Res 50:503-8. 2001
  7. ncbi request reprint A 10-kda fragment of fibronectin type III domain is a neutrophil chemoattractant purified from conditioned medium of rat granulation tissue
    S Shiota
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Biol Pharm Bull 24:835-7. 2001
  8. pmc Identification of cytokine-induced neutrophil chemoattractants (CINC), rat GRO/CINC-2 alpha and CINC-2 beta, produced by granulation tissue in culture: purification, complete amino acid sequences and characterization
    H Nakagawa
    Department of Biochemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Biochem J 301:545-50. 1994
  9. ncbi request reprint Production of an interleukin-8-like chemokine by cytokine-stimulated rat NRK-49F fibroblasts and its suppression by anti-inflammatory steroids
    H Nakagawa
    Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Biochem Pharmacol 45:1425-30. 1993
  10. ncbi request reprint The expression of three types of CINCs by lipopolysaccharide-stimulated rat macrophages is inhibited similarly by anti-inflammatory steroids
    F Shibata
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Inflamm Res 49:80-5. 2000

Collaborators

Detail Information

Publications34

  1. ncbi request reprint A 16-kDa fragment of collagen type XIV is a novel neutrophil chemotactic factor purified from rat granulation tissue
    H Nakagawa
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Toyama, Sugitani, 930 0194, Japan
    Biochem Biophys Res Commun 256:642-5. 1999
    ..The results suggest that the novel chemoattractant plays a role in neutrophil recruitment in rat inflammation...
  2. ncbi request reprint Differential production of chemokines and their role in neutrophil infiltration in rat allergic inflammation
    H Nakagawa
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Sugitani, Japan
    Int Arch Allergy Immunol 115:137-43. 1998
    ....
  3. ncbi request reprint Cytokine-induced neutrophil chemoattractant (CINC)-2 alpha, a novel member of rat GRO/CINCs, is a predominant chemokine produced by lipopolysaccharide-stimulated rat macrophages in culture
    H Nakagawa
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyoma Medical and Pharmaceutical University, Japan
    Biochem Biophys Res Commun 220:945-8. 1996
    ..The results suggest that CINC-2alpha is produced by activated macrophages in vivo and plays an important role in the infiltration of neutrophils into inflammatory sites in rats..
  4. ncbi request reprint Identification of a common receptor for three types of rat cytokine-induced neutrophil chemoattractants (CINCs)
    F Shibata
    Department of Physiological Chemistry, Toyama Medical and Pharmaceutical University, Sugitani, Toyama 930 0194, Japan
    Cytokine 12:1368-73. 2000
    ..The results indicate that rat CXCR2 on neutrophils is the unique receptor for all three types of CINCs, and CINC-1/-2 and CINC-3 exert different biological activities through the common receptor...
  5. ncbi request reprint Differential changes in the concentrations of cytokine-induced neutrophil chemoattractant (CINC)-1 and CINC-2 in exudate during rat lipopolysaccharide-induced inflammation
    F Shibata
    Department of Physiological Chemistry, Toyama Medical and Pharmaceutical University, Sugitani, Toyana, Japan
    Cytokine 8:222-6. 1996
    ..The results suggest that CINC-2 as well as CINC-1 plays an important role in accumulation of neutrophils into the inflammatory lesion of LPS- induced inflammation in rats...
  6. ncbi request reprint Contribution of cytokine-induced neutrophil chemoattractant CINC-2 and CINC-3 to neutrophil recruitment in lipopolysaccharide-induced inflammation in rats
    K Takano
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Inflamm Res 50:503-8. 2001
    ....
  7. ncbi request reprint A 10-kda fragment of fibronectin type III domain is a neutrophil chemoattractant purified from conditioned medium of rat granulation tissue
    S Shiota
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Biol Pharm Bull 24:835-7. 2001
    ....
  8. pmc Identification of cytokine-induced neutrophil chemoattractants (CINC), rat GRO/CINC-2 alpha and CINC-2 beta, produced by granulation tissue in culture: purification, complete amino acid sequences and characterization
    H Nakagawa
    Department of Biochemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Biochem J 301:545-50. 1994
    ..Rat GRO/CINC-2 alpha is a major chemokine, and the four purified chemokines have similar chemotactic activity, suggesting that they contribute to neutrophil infiltration into inflammatory sites in rats...
  9. ncbi request reprint Production of an interleukin-8-like chemokine by cytokine-stimulated rat NRK-49F fibroblasts and its suppression by anti-inflammatory steroids
    H Nakagawa
    Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Biochem Pharmacol 45:1425-30. 1993
    ..On the other hand, the non-steroidal anti-inflammatory drugs (indomethacin and piroxicam) at 10(-7)-10(-5) M showed no apparent inhibitory effect on rat gro/CINC production by NRK-49F cells stimulated with IL-1 beta...
  10. ncbi request reprint The expression of three types of CINCs by lipopolysaccharide-stimulated rat macrophages is inhibited similarly by anti-inflammatory steroids
    F Shibata
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Inflamm Res 49:80-5. 2000
    ..We examined whether the expression of CINCs in lipopolysaccharide-stimulated rat macrophages is similarly inhibited by anti-inflammatory drugs...
  11. ncbi request reprint Rat macrophage inflammatory protein-1alpha, a CC chemokine, acts as a neutrophil chemoattractant in vitro and in vivo
    K Takano
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Inflammation 23:411-24. 1999
    ..Our results suggest that rMIP-1alpha acts as a neutrophil chemoattractant and, together with CINCs, plays an important role in infiltration of neutrophils into inflammatory sites in rats...
  12. ncbi request reprint Gene structure, cDNA cloning, and expression of the rat cytokine-induced neutrophil chemoattractant-2 (CINC-2) gene
    F Shibata
    Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    Cytokine 10:169-74. 1998
    ..However, the mRNA level of CINC-2 remained high 24 h after stimulation, in contrast to that of CINC-1 or CINC-3. These data indicate the expression of CINC-2 is regulated differently among the CINCs...
  13. ncbi request reprint The neutrophil chemoattractant produced by the rat kidney epithelioid cell line NRK-52E is a protein related to the KC/gro protein
    K Watanabe
    Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan
    J Biol Chem 264:19559-63. 1989
    ....
  14. pmc Social class difference in catch up growth in a national British cohort
    H Teranishi
    Department of Public Health, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama 930 0194, Japan
    Arch Dis Child 84:218-21. 2001
    ..To examine the influence of socioeconomic status on growth pattern in height from age 7 to 23 years...
  15. ncbi request reprint UT841 purified from sea urchin (Toxopneustes pileolus) venom inhibits time-dependent (45)Ca(2+) uptake in crude synaptosome fraction from chick brain
    Y Zhang
    Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Kinki University, Kowakae, 577-8502, Higashi-Osaka, Japan
    Toxicon 39:1223-9. 2001
    ..45)Ca(2+) uptake. These results suggest that UT841 purified from sea urchin venom may affect Time-dep. (45)Ca(2+) uptake through the metabolism of some lipids and nitric oxide...
  16. ncbi request reprint Ion-selective electrode for transmembrane pH difference measurements
    T Katsu
    Faculty of Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700 8530, Japan
    Anal Chem 73:1849-54. 2001
    ..The transmembrane pH differences in Escherichia coli cells and the light-induced pH differences across the envelope vesicles of Halobacterium halobium were successfully determined by the present method...
  17. ncbi request reprint Characteristic alterations of cutaneous neurogenic factors in photoaged skin
    M Toyoda
    Department of Dermatology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan uruoihifuka
    Br J Dermatol 153:13-22. 2005
    ..Although it has been recognized that photoageing and chronological ageing differ in various morphological and biological aspects, the characteristic alterations of cutaneous neurogenic factors in photoaged skin are poorly characterized...
  18. ncbi request reprint Intercellular localization of acid invertase in tomato fruit and molecular cloning of a cDNA for the enzyme
    T Sato
    Division of Bioproduction Science, Faculty of Horticulture, Chiba University, Japan
    Plant Cell Physiol 34:263-9. 1993
    ..RNA blot analysis indicated that the mRNA for the acid invertase was about 2.5 kb in length. The levels of the mRNA were low at the mature green stage but increased during ripening of fruit...
  19. ncbi request reprint Retinoic acid-inducible gene-I is induced by interleukin-1beta in cultured human gingival fibroblasts
    H Sakaki
    Department of Dentistry and Oral Surgery, Institute of Brain Science, Hirosaki University School of Medicine, Hirosaki, Japan
    Oral Microbiol Immunol 20:47-50. 2005
    ..In contrast, RIG-I overexpression did not alter the level of mRNA for monocyte chemoattractant protein-1. We conclude that IL-1beta stimulates RIG-I expression in human gingival fibroblasts...
  20. ncbi request reprint Expression profiling of cancer-related genes in human keratinocytes following non-lethal ultraviolet B irradiation
    T Murakami
    Department of Dermatology, Jichi Medical School, 3311 1 Yakushiji, Minamikawachi Machi, Kawachi gun, Tochigi 329 0498, Japan
    J Dermatol Sci 27:121-9. 2001
    ..Although the roles of these cellular genes after UVB-irradiation remain to be elucidated, microarray analysis may provide a new view of gene expression in epidermal keratinocytes following UVB exposure...
  21. ncbi request reprint Gene gun-mediated oral mucosal transfer of interleukin 12 cDNA coupled with an irradiated melanoma vaccine in a hamster model: successful treatment of oral melanoma and distant skin lesion
    J Wang
    Division of Organ Replacement Research, Center for Molecular Medicine, Jichi Medical School, Tochigi 329-0498, Japan
    Cancer Gene Ther 8:705-12. 2001
    ....
  22. ncbi request reprint Late infantile Hirschsprung disease-mental retardation syndrome with a 3-bp deletion in ZFHX1B
    M Yoneda
    Second Department of Internal Medicine, Fukui Medical University, Fukui, Japan
    Neurology 59:1637-40. 2002
    ..This suggests that screening for ZFHX1B mutations is warranted even in the absence of typical clinical features of the syndrome...
  23. ncbi request reprint Isolation of a novel gene on 8p21.3-22 whose expression is reduced significantly in human colorectal cancers with liver metastasis
    T Oyama
    Division of Clinical Genetics, Biomedical Research Center, Osaka University School of Medicine, Osaka, Japan
    Genes Chromosomes Cancer 29:9-15. 2000
    ..Furthermore, we identified somatic mutations of this gene in a colorectal cancer, a hepatocellular carcinoma, and a nonsmall lung cancer among 111 human tumors of various stages examined...
  24. ncbi request reprint Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src
    S Nada
    Division of Protein Metabolism, Osaka University, Japan
    Nature 351:69-72. 1991
    ..These results suggest that this protein-tyrosine kinase, which might negatively regulate p60c-src, represents a new type of tyrosine kinase...
  25. ncbi request reprint A high molecular mass protein isolated from chicken gizzard: its localization at the dense plaques and dense bodies of smooth muscle and the Z-disks of skeletal muscle
    A G Terasaki
    Department of Biology, Faculty of Science, Chiba University, Japan
    J Cell Sci 108:857-68. 1995
    ..abstract truncated at 250 words)..
  26. ncbi request reprint cDNA cloning and expression of a novel human desmocollin
    K Kawamura
    Institute of Cytosignal Research Inc, Tokyo, Japan
    J Biol Chem 269:26295-302. 1994
    ..These findings suggest that our clone might be a new member of the desmocollin family, and we have tentatively called this clone human desmocollin type 4...
  27. ncbi request reprint Differential expression of D type cyclins during neuronal maturation
    T Tamaru
    Division of Protein Metabolism, Osaka University, Japan
    Neurosci Lett 168:229-32. 1994
    ..These data suggest differential roles of the D type cyclins in the process of neuronal differentiation and/or function...
  28. ncbi request reprint Newly identified genes involved in the signal transduction of Escherichia coli K-12
    R Utsumi
    Department of Agricultural Chemistry, Kinki University, Nara, Japan
    Gene 140:73-7. 1994
    ..pertussis via BvgA and BvgS. These results indicate that the newly cloned genes were structurally and functionally similar to bvgA and bvgS, and we designated these genes evgA and evgS...
  29. ncbi request reprint Cloning of rat lysosomal acid lipase cDNA and identification of the mutation in the rat model of Wolman's disease
    H Nakagawa
    Third Department of Internal Medicine, Kagoshima University School of Medicine, Japan
    J Lipid Res 36:2212-8. 1995
    ..These results identify the molecular defect in the Wolman RLAL, and suggest that the C-terminus of RLAL is essential for the activity and/or stability of the enzyme...
  30. ncbi request reprint The targeting of the cyclin D1 oncogene by an Epstein-Barr virus promoter in transgenic mice causes dysplasia in the tongue, esophagus and forestomach
    H Nakagawa
    Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Oncogene 14:1185-90. 1997
    ..This transgenic model is useful in demonstrating cyclin D1 may be a tumor initiating event in aero-upper digestive squamous epithelial tissues...
  31. ncbi request reprint A 260-kDa filamin/ABP-related protein in chicken gizzard smooth muscle cells is a new component of the dense plaques and dense bodies of smooth muscle
    M Tachikawa
    Department of Biology, Faculty of Science, Chiba University
    J Biochem 122:314-21. 1997
    ..Its amino acid sequence, molecular size, immunological reactivity, and localization in smooth muscle thus indicated that cgABP260 is a new component of the dense plaques and dense bodies of smooth muscle cells...
  32. pmc Molecular cloning and expression of chicken C-terminal Src kinase: lack of stable association with c-Src protein
    H Sabe
    Laboratory of Molecular Oncology, Rockefeller University, New York, NY 10021 6399
    Proc Natl Acad Sci U S A 89:2190-4. 1992
    ..Although some portions of CSK were found in a membrane fraction, no complex formation between CSK and c-Src was observed, suggesting that the src homology 2 domain of CSK does not play a role in the direct interaction of c-Src...
  33. ncbi request reprint Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family
    N Hiraoka
    Glycobiology Program, Cancer Research Center, The Burnham Institute, La Jolla, California 92037, USA
    J Biol Chem 275:20188-96. 2000
    ..These results indicate C4ST-1 and C4ST-2 play complementary roles in chondroitin and dermatan sulfate synthesis in different tissues...
  34. ncbi request reprint Retinoic acid-inducible gene-I is induced in gingival fibroblasts by lipopolysaccharide or poly IC: possible roles in interleukin-1beta, -6 and -8 expression
    K Kubota
    Department of Dentistry and Oral Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Oral Microbiol Immunol 21:399-406. 2006
    ..RIG-I may have important roles in the innate immune response in the regulation of IL-1beta, IL-6 and IL-8 expression in gingival fibroblasts in response to LPS and dsRNA...