M Tanaka

Summary

Affiliation: Tokyo Metropolitan Institute of Gerontology
Country: Japan

Publications

  1. pmc Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan
    Erhan Bilal
    BioMaPS Institute, Rutgers University, Piscataway, New Jersey, United States of America
    PLoS ONE 3:e2421. 2008
  2. pmc Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes
    Kumpei Tanisawa
    Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, 35 2 Sakae cho, Tokyo, Itabashi, Japan
    BMC Genomics 14:248. 2013
  3. pmc Establishment of a new method for precisely determining the functions of individual mitochondrial genes, using Dictyostelium cells
    Junji Chida
    Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Aoba, Sendai 980 8578, Japan
    BMC Genet 9:25. 2008
  4. ncbi request reprint Information integration about object-object relationships by chimpanzees (Pan troglodytes)
    M Tanaka
    Department of Behavioral and Brain Sciences, Primate Research Institute, Kyoto University, Japan
    J Comp Psychol 110:323-35. 1996
  5. ncbi request reprint Women with mitochondrial haplogroup N9a are protected against metabolic syndrome
    Masashi Tanaka
    Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology Tokyo, 35 2 Sakae cho, Itabashi ku, Tokyo 173 0015, Japan
    Diabetes 56:518-21. 2007
  6. ncbi request reprint Polymorphisms in the control region of mitochondrial DNA associated with elite Japanese athlete status
    E Mikami
    Graduate School of Sport Sciences, Waseda University, Saitama, Japan Japan Society for the Promotion of Science, Tokyo, Japan Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
    Scand J Med Sci Sports 23:593-9. 2013
  7. doi request reprint Mitochondrial macrohaplogroup associated with muscle power in healthy adults
    N Fuku
    Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
    Int J Sports Med 33:410-4. 2012
  8. ncbi request reprint Relation between myoglobin and cardiac dysfunction in myocarditis--immunohistochemical study of endomyocardial biopsy specimens
    K Horike
    Department of Internal Medicine, Faculty of Medicine, Kyoto University, Japan
    Jpn Circ J 55:24-32. 1991
  9. ncbi request reprint Genetic risk for metabolic syndrome: examination of candidate gene polymorphisms related to lipid metabolism in Japanese people
    Y Yamada
    Department of Human Functional Genomics, Life Science Research Center, Mie University, 1577 Kurima machiya, Tsu, Mie 514 8507, Japan
    J Med Genet 45:22-8. 2008
  10. ncbi request reprint Long-term results of tacrolimus therapy for renal transplantation in patients with diabetic nephropathy in Japan
    A Sugitani
    Department of Surgery and Oncology, Kyushu University School of Medicine, Maidashi, Fukuoka, Japan
    Transplant Proc 37:1767-8. 2005

Collaborators

Detail Information

Publications47

  1. pmc Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan
    Erhan Bilal
    BioMaPS Institute, Rutgers University, Piscataway, New Jersey, United States of America
    PLoS ONE 3:e2421. 2008
    ..The fact that the correlations are from the population structure suggests that hitch-hiking on autosomal events is a possible explanation for the observed correlations...
  2. pmc Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes
    Kumpei Tanisawa
    Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, 35 2 Sakae cho, Tokyo, Itabashi, Japan
    BMC Genomics 14:248. 2013
    ....
  3. pmc Establishment of a new method for precisely determining the functions of individual mitochondrial genes, using Dictyostelium cells
    Junji Chida
    Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Aoba, Sendai 980 8578, Japan
    BMC Genet 9:25. 2008
    ..This is the reason why we tried to establish a novel method for disrupting a certain mitochondrial gene (rps4), using Dictyostelium cells...
  4. ncbi request reprint Information integration about object-object relationships by chimpanzees (Pan troglodytes)
    M Tanaka
    Department of Behavioral and Brain Sciences, Primate Research Institute, Kyoto University, Japan
    J Comp Psychol 110:323-35. 1996
    ..The results suggest that the subject might integrate information about relationships acquired in Experiment 1 and organize it to make networks of related items...
  5. ncbi request reprint Women with mitochondrial haplogroup N9a are protected against metabolic syndrome
    Masashi Tanaka
    Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology Tokyo, 35 2 Sakae cho, Itabashi ku, Tokyo 173 0015, Japan
    Diabetes 56:518-21. 2007
    ..22 (0.06-0.68, P = 0.0129) for G1 and with an OR of 0.32 (0.10-0.96, P = 0.0469) for D5, respectively. These results indicate that mitochondrial haplogroup N9a may be a protective factor against metabolic syndrome in Japanese women...
  6. ncbi request reprint Polymorphisms in the control region of mitochondrial DNA associated with elite Japanese athlete status
    E Mikami
    Graduate School of Sport Sciences, Waseda University, Saitama, Japan Japan Society for the Promotion of Science, Tokyo, Japan Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
    Scand J Med Sci Sports 23:593-9. 2013
    ..3% and 10.0%, respectively. These findings imply that several polymorphisms detected in the control region of mtDNA may influence physical performance probably in a functional manner...
  7. doi request reprint Mitochondrial macrohaplogroup associated with muscle power in healthy adults
    N Fuku
    Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
    Int J Sports Med 33:410-4. 2012
    ..In conclusion, mitochondrial macrohaplogroup N may be one of the determinant factors of anaerobic physical performance phenotype such as muscle power...
  8. ncbi request reprint Relation between myoglobin and cardiac dysfunction in myocarditis--immunohistochemical study of endomyocardial biopsy specimens
    K Horike
    Department of Internal Medicine, Faculty of Medicine, Kyoto University, Japan
    Jpn Circ J 55:24-32. 1991
    ..These results indicate that myoglobin staining reflects the intensity of myocarditis and a decrease of myoglobin may be important as one of the pathogenetic factors of cardiac dysfunction in myocarditis...
  9. ncbi request reprint Genetic risk for metabolic syndrome: examination of candidate gene polymorphisms related to lipid metabolism in Japanese people
    Y Yamada
    Department of Human Functional Genomics, Life Science Research Center, Mie University, 1577 Kurima machiya, Tsu, Mie 514 8507, Japan
    J Med Genet 45:22-8. 2008
    ..The aim of this study was to identify genetic polymorphisms that confer susceptibility to metabolic syndrome, to allow prediction of genetic risk for this condition...
  10. ncbi request reprint Long-term results of tacrolimus therapy for renal transplantation in patients with diabetic nephropathy in Japan
    A Sugitani
    Department of Surgery and Oncology, Kyushu University School of Medicine, Maidashi, Fukuoka, Japan
    Transplant Proc 37:1767-8. 2005
    ..Tacrolimus was also beneficial in association with simultaneous pancreas and kidney transplantation. These data encourage us to perform kidney transplantation in patients with diabetic nephropathy...
  11. ncbi request reprint A new congenital form of X-linked autophagic vacuolar myopathy
    C Yan
    Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187 8502, Japan
    Neurology 65:1132-4. 2005
    ..Haplotype analysis suggests that this new AVM and XMEA may be allelic despite different clinical presentations...
  12. ncbi request reprint Aleukaemic leukaemia cutis as an initial manifestation of myeloid/NK cell precursor acute leukaemia
    I Dekio
    Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
    J Eur Acad Dermatol Venereol 20:453-6. 2006
    ..This is the first case report of myeloid/NK cell precursor acute leukaemia presenting as aleukaemic leukaemia cutis in the English literature, and awareness of this clinical presentation may be important to reach the correct diagnosis...
  13. ncbi request reprint Anti-aquaporin 4 antibody in selected Japanese multiple sclerosis patients with long spinal cord lesions
    K Tanaka
    Department of Neurology, Brain Research Institute, Niigata University, Niigata Japan
    Mult Scler 13:850-5. 2007
    ..Patients with OSMS without LCL and those with CMS were negative for this antibody. Our results accorded with those of Lennon et al. suggest that Japanese OSMS with LCL may have an underlying pathogenesis in common with NMO...
  14. ncbi request reprint Clinical assessment of oral malodor by the electronic nose system
    M Tanaka
    Department of Preventive Dentistry, Graduate School of Dentistry, Osaka University, 1 8, Yamadaoka, Suita, Osaka 565 0871, Japan
    J Dent Res 83:317-21. 2004
    ..Our findings suggest that the top-note score from an electronic nose examination may be useful for the clinical evaluation of oral malodor...
  15. ncbi request reprint Characteristics of pancreas transplantation currently performed in japan
    M Ishibashi
    Department of Urology, Nara Medical University, Kashihara, Japan
    Transplant Proc 36:1086-9. 2004
    ..The revascularization of gastroduodenal artery to the pancreatic graft was performed in eight cases to minimize the risk of ischemic injury to the pancreatic graft and technical failure in cases of marginal donor...
  16. ncbi request reprint Characteriation of clinical data packages using foreign data in new drug applications in Japan
    M Tanaka
    Japan Pharmaceutical Manufacturers Association, Drug Evaluation Committee, Tokyo, Japan
    Clin Pharmacol Ther 84:340-6. 2008
    ..Given the differences in approval requirements among regions, the acceptability of foreign clinical data to Japanese approval is limited...
  17. ncbi request reprint Development of a broadband telemedical network based on internet protocol in the Asia-Pacific region
    N Nakashima
    Department of Medical Informatics, Kyushu University Faculty of Medicine, Maidashi 3 1 1, Higashi ku, Fukuoka 812 8582, Japan
    Methods Inf Med 46:709-15. 2007
    ..To promote the exchange of knowledge and standardization of medical procedures and medical systems in the Asia-Pacific region, we established a medical network with high-quality moving images over broadband Internet lines in February 2003...
  18. ncbi request reprint Coexistence of familial Mediterranean fever and Sjögren's syndrome in a Japanese patient
    M Tanaka
    Clin Exp Rheumatol 25:792. 2007
  19. ncbi request reprint Age-stratified serum levels of isoflavones and proportion of equol producers in Japanese and Korean healthy men
    K Fujimoto
    Department of Urology, Nara Medical University, Kashihara, Japan
    Prostate Cancer Prostatic Dis 11:252-7. 2008
    ..Elucidating the mechanism of equol production may be promising in developing strategies for chemoprevention against prostate cancer...
  20. ncbi request reprint [Multidisciplinary treatment of lung cancer in 21st century]
    Hirokazu Aikawa
    Department of Thoracic Surgery, Kanazawa Medical University, Kanazawa, Japan
    Kyobu Geka 61:51-4. 2008
    ..In this paper, we introduce The 21st Century Multidisciplinary Center in Kanazawa Medical University, and the Hokuriku Training Program for Making Specialists in Cancer Treatment...
  21. pmc Genetic features of clinical isolates of Streptococcus dysgalactiae subsp. equisimilis possessing Lancefield's group A antigen
    Daisuke Tanaka
    Graduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama 930 8555, Japan
    J Clin Microbiol 46:1526-9. 2008
    ..The results indicate that a conserved clone has persisted and spread within Japan, and two different emm types were observed within members of this clone...
  22. ncbi request reprint [Prevalence rate of severely mentally and physically handicapped children in school age in Yokohama]
    T Miyakawa
    Department of Child Neurology, Kanagawa Children's Medical Center, Yokohama
    No To Hattatsu 24:50-3. 1992
    ..8%) lived with their families. 2) eighty-eight percent of the children attended school for retarded children. 3) about twenty percent of the children who attended school needed tube feeding...
  23. doi request reprint Novel mutations in Myoclonin1/EFHC1 in sporadic and familial juvenile myoclonic epilepsy
    M T Medina
    Neurology Training Program, National Autonomous University of Honduras, Tegucigalpa, Honduras
    Neurology 70:2137-44. 2008
    ..Juvenile myoclonic epilepsy (JME) accounts for 3 to 12% of all epilepsies. In 2004, the GENESS Consortium demonstrated four missense mutations in Myoclonin1/EFHC1 of chromosome 6p12.1 segregating in 20% of Hispanic families with JME...
  24. ncbi request reprint Genetic risk for myocardial infarction determined by polymorphisms of candidate genes in a Japanese population
    Y Yamada
    Department of Human Functional Genomics, Life Science Research Center, Mie University, 1577 Kurima machiya, Tsu, Mie 514 8507, Japan
    J Med Genet 45:216-21. 2008
    ..Although several environmental factors influence the development of myocardial infarction (MI), genetic factors have been shown to contribute to individual susceptibility to this condition...
  25. ncbi request reprint Pancreas-kidney transplantation in Japan: impact of cyclosporine on the development of immunosuppressive therapy
    A Sugitani
    Central Pancreas Transplantation Committee, Graduate College of Medical Sciences, Kyushu University, Fukuoka, Japan
    Transplant Proc 36:356S-361S. 2004
    ..This investigation presents the results of pancreas-kidney transplantation in Japan, in comparison with those worldwide, and describes a recent case in Japan...
  26. ncbi request reprint Association of ALDH(2) genotypes and alcohol consumption with periodontitis
    N Nishida
    Department of Preventive Dentistry, Osaka University Graduate School of Dentistry, 1 8, Yamadaoka, Suita, Osaka 565 0871, Japan
    J Dent Res 83:161-5. 2004
    ..Our results suggest that alcohol consumption may be a risk indicator for periodontitis in ALDH(2)*1/*2 subjects who consume larger amounts of alcohol...
  27. ncbi request reprint Analysis of 168 short tandem repeat loci in the Japanese population, using a screening set for human genetic mapping
    M Mizutani
    Department of Legal Medicine and Bioethics, Graduate School of Medicine, Nagoya University, Japan
    J Hum Genet 46:448-55. 2001
    ..The present basic study of allele frequency databases of these STRs will contribute to further applications in forensic science and human genetics...
  28. ncbi request reprint Association of a G994 --> T (Val279 --> Phe) polymorphism of the plasma platelet-activating factor acetylhydrolase gene with myocardial damage in Japanese patients with nonfamilial hypertrophic cardiomyopathy
    Y Yamada
    Department of Gene Therapy, Gifu International Institute of Biotechnology, Yagi Memorial Park, Kani gun, Japan
    J Hum Genet 46:436-41. 2001
    ....
  29. ncbi request reprint Association of the C-509-->T polymorphism, alone of in combination with the T869-->C polymorphism, of the transforming growth factor-beta1 gene with bone mineral density and genetic susceptibility to osteoporosis in Japanese women
    Y Yamada
    Department of Gene Therapy, Gifu International Institute of Biotechnology, Mitake, Japan
    J Mol Med (Berl) 79:149-56. 2001
    ....
  30. ncbi request reprint Surgical treatment of patients with T2 gallbladder carcinoma invading the subserosal layer
    K Chijiiwa
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Am Coll Surg 192:600-7. 2001
    ..The presence of lymph node metastasis, perineural invasion, or both suggests the necessity of additional treatment after radical surgery...
  31. ncbi request reprint Exon 3 of tyrosine hydroxylase gene: lack of association with Japanese schizophrenic patients
    M Ota
    Department of Neuropsychiatry, Tosei General Hospital, Seto 489 8642, Japan
    Mol Psychiatry 6:315-9. 2001
    ..These results indicate that exon 3 of the human TH gene lacks association with schizophrenia in Japanese patients...
  32. ncbi request reprint Antiatherogenic mitochondrial genotype in patients with type 2 diabetes
    H Matsunaga
    Department of Medicine, Metabolism and Endocrinology, Juntendo University, Tokyo, Japan
    Diabetes Care 24:500-3. 2001
    ..CONCLUSIONS: The Mt5178A genotype may be unrelated to the etiology of type 2 diabetes. However, Mt5178A seems to have an antiatherogenic effect, at least in type 2 diabetic individuals...
  33. ncbi request reprint Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease
    N Hattori
    Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan
    Genomics 49:52-8. 1998
    ..40 (95% CI: 1.18-4.88). NDUFV2 constitutes one genetic risk factor for PD, and the mutation may well be a cause of complex I deficiency in this disease...
  34. ncbi request reprint Antigenic protein specific for C3H strain mouse is a mitochondrial stress-70 protein
    Y Michikawa
    Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan
    Biochem Biophys Res Commun 196:223-32. 1993
    ..Thus, it is interesting that a genetic marker sequence in mice is located on the gene encoding a mitochondrial stress-70 protein...
  35. ncbi request reprint [Mortality patterns of children with epilepsies in a children's medical center]
    S Miyake
    Division of Neurology, Kanagawa Children's Medical Center, Yokohama
    No To Hattatsu 23:329-35. 1991
    ..About a half of them (7 cases) died at home. Adequate managements appeared necessary to prevent accidental deaths of children with epilepsies...
  36. pmc Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study
    H J Andreyev
    Department of Medicine and Therapeutics, Imperial College School of Medicine, Chelsea and Westminster Hospital, 369 Fulham Road, London, SW10 9NH, UK
    Br J Cancer 85:692-6. 2001
    ....
  37. ncbi request reprint Unique mutations in mitochondrial DNA of senescence-accelerated mouse (SAM) strains
    J Mizutani
    Department of Aging Angiology, Research Center on Aging and Adaptation, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan
    J Hered 92:352-5. 2001
    ..The polymorphism in mtDNA could be used to ascertain the genealogy of other mouse strains as well...
  38. ncbi request reprint Laparoscopic pancreatic surgery: current indications and surgical results
    S Shimizu
    Department of Endoscopic Diagnostics and Therapeutics, Kyushu University Faculty of Medicine, Fukuoka 812 8582, Japan
    Surg Endosc 18:402-6. 2004
    ..The purpose of this study was to evaluate the outcomes and feasibility of laparoscopic pancreatic surgery...
  39. ncbi request reprint Reliability of clinical parameters for predicting the outcome of oral malodor treatment
    M Tanaka
    Department of Preventive Dentistry, Graduate School of Dentistry, Osaka University, 1 8, Yamadaoka, Suita, Osaka 565 0871, Japan
    J Dent Res 82:518-22. 2003
    ..These results suggest that malodor- and periodontal-disease-related parameters and self-estimation of malodor at baseline are effective for prediction of outcome...
  40. ncbi request reprint Association between adult-onset Still's disease and interleukin-18 gene polymorphisms
    T Sugiura
    Institute of Rheumatology, Tokyo Women s Medical University School of Medicine, Tokyo, Japan
    Genes Immun 3:394-9. 2002
    ..65) and the RA patients (P=0.015, Fischer's exact probability test, OR=4.0, 95% CI=1.39-11.54). We therefore conclude that possession of the diplotype configuration of S01/S01 is a major genetic risk factor for susceptibility to AOSD...
  41. ncbi request reprint Abnormal expression of E-cadherin and beta-catenin may be a molecular marker of submucosal invasion and lymph node metastasis in early gastric cancer
    M Tanaka
    Department of Surgery, Saga Medical School, 5 1 1 Nabeshima, Saga, 849 8501, Japan
    Br J Surg 89:236-44. 2002
    ....
  42. ncbi request reprint Biopsy pathology predicts patients with ulcerative colitis subsequently requiring surgery
    M Tanaka
    Dept of Pathology, Hirosaki University School of Medicine, Japan
    Scand J Gastroenterol 37:200-5. 2002
    ..The aim of this study was to elucidate comprehensive criteria consisting of specific histologic features enabling the prediction of failure to medical treatment...
  43. ncbi request reprint Association between proline-requiring auxotype and fluoroquinolone resistance in Neisseria gonorrhoeae isolated in Japan
    H Tsunoe
    Department of Urology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
    J Infect Chemother 7:218-23. 2001
    ..gonorrhoeae isolates with GyrA and ParC substitutions may be mainly caused by the dissemination of a single clone in the community...
  44. ncbi request reprint Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells
    T Yamamoto
    Research Centre of Health, Physical Fitness and Sports, Nagoya University, Chikusa ku, Nagoya, Japan
    J Neural Transm 109:1-13. 2002
    ..These results suggest that ONOO- may induce mitochondrial dysfunction and cell death in neurons through nitration of mitochondrial complex I subunits...
  45. ncbi request reprint Postoperative pancreatic exocrine function influences body weight maintenance after pylorus-preserving pancreatoduodenectomy
    T Ohtsuka
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, Japan
    Am J Surg 182:524-9. 2001
    ..23). CONCLUSIONS: In patients refractory to an ordinary amount of medicine, a large dosage of enzymes may be necessary to gain weight after PPPD...
  46. ncbi request reprint Assessment of air pollution in Nagasaki City: determination of polycyclic aromatic hydrocarbons and their nitrated derivatives, and some metals
    M Wada
    School of Pharmaceutical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan
    Environ Pollut 115:139-47. 2001
    ..The correlation coefficients between total PAHs or NPAHs and traffic volume were 0.781 and 0.818, respectively. These results suggested that one of the main sources for NPAHs and PAHs in a city area might be motor vehicles...
  47. ncbi request reprint Clinical application of the ventricular assist devices in Japan
    S Nitta
    Department of Medical Engineering and Cardiology, Tohoku University, Sendai, Japan
    Sci Rep Res Inst Tohoku Univ Med 38:5-10. 1991
    ..Original diseases were 50% ischemic heart disease and 37% valvular disease. Duration of assistance ranged from one hour to 70 days. Thirty-one cases weaned from ventricular assistance and 11 cases became long-time survivors...