Hisashi Sakamaki

Summary

Affiliation: Tokyo Metropolitan Komagome Hospital
Country: Japan

Publications

  1. doi request reprint Allogeneic stem cell transplantation versus chemotherapy as post-remission therapy for intermediate or poor risk adult acute myeloid leukemia: results of the JALSG AML97 study
    Hisashi Sakamaki
    Division of Hematology, Tokyo Metropolitan Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo 113 8677, Japan
    Int J Hematol 91:284-92. 2010
  2. doi request reprint Prospective multicenter study of single-unit cord blood transplantation with myeloablative conditioning for adult patients with high-risk hematologic malignancies
    Takehiko Mori
    Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
    Biol Blood Marrow Transplant 19:486-91. 2013
  3. doi request reprint A high risk of life-threatening infectious complications in mycophenolate mofetil treatment for acute or chronic graft-versus-host disease
    Chie Onishi
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Int J Hematol 91:464-70. 2010
  4. ncbi request reprint Second allogeneic transplantation for relapsed acute leukemia after initial allogeneic hematopoietic stem cell transplantation
    Ryo Hanajiri
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Pathol Oncol Res 18:1003-8. 2012
  5. ncbi request reprint A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult L
    Shuichi Miyawaki
    Division of Hematology, Saiseikai Maebashi Hospital, Maebashi, Japan
    Cancer 104:2726-34. 2005
  6. doi request reprint Related transplantation with HLA-1 Ag mismatch in the GVH direction and HLA-8/8 allele-matched unrelated transplantation: a nationwide retrospective study
    Junya Kanda
    Division of Hematology, Saitama Medical Center, Jichi Medical University, Japan
    Blood 119:2409-16. 2012
  7. doi request reprint Leukemic infiltration of the lung following allogeneic hematopoietic stem cell transplantation
    Kazuhiko Kakihana
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Int J Hematol 89:118-22. 2009
  8. doi request reprint Clinical features of dasatinib-induced large granular lymphocytosis and pleural effusion
    Yasunobu Nagata
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Int J Hematol 91:799-807. 2010
  9. doi request reprint Intracranial hemorrhage following allogeneic hematopoietic stem cell transplantation
    Yuho Najima
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo 113 8677, Japan
    Am J Hematol 84:298-301. 2009
  10. doi request reprint Correlation between survival and number of mobilized CD34+ cells in patients with multiple myeloma or Waldenström macroglobulinemia
    Kazuhiko Kakihana
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Disease Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo 113 8677, Japan
    Pathol Oncol Res 16:583-7. 2010

Detail Information

Publications44

  1. doi request reprint Allogeneic stem cell transplantation versus chemotherapy as post-remission therapy for intermediate or poor risk adult acute myeloid leukemia: results of the JALSG AML97 study
    Hisashi Sakamaki
    Division of Hematology, Tokyo Metropolitan Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo 113 8677, Japan
    Int J Hematol 91:284-92. 2010
    ..088). The OS benefit was seen in the patients aged 36-50 years old (49 vs. 24%; p = 0.031), suggesting an advantage of allo-HSCT among older patients with leukemia that is more resistant to chemotherapy than that among younger patients...
  2. doi request reprint Prospective multicenter study of single-unit cord blood transplantation with myeloablative conditioning for adult patients with high-risk hematologic malignancies
    Takehiko Mori
    Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
    Biol Blood Marrow Transplant 19:486-91. 2013
    ..These results suggest that the IMSUT CBT procedures can safely provide a high disease-free survival rate in patients with high-risk hematologic malignancies...
  3. doi request reprint A high risk of life-threatening infectious complications in mycophenolate mofetil treatment for acute or chronic graft-versus-host disease
    Chie Onishi
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Int J Hematol 91:464-70. 2010
    ..5-67 months), 10 patients (39%) died. This small study demonstrates that MMF offers an alternative tool for rescuing steroid-refractory or steroid-dependent GVHD, but increases the risk of developing life-threatening infection...
  4. ncbi request reprint Second allogeneic transplantation for relapsed acute leukemia after initial allogeneic hematopoietic stem cell transplantation
    Ryo Hanajiri
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Pathol Oncol Res 18:1003-8. 2012
    ..45-13.2; P = 0.009). Although outcomes for patients with relapsed leukemia were generally poor, our results suggest that second HSCT could offer a survival advantage over other conventional salvage strategies...
  5. ncbi request reprint A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult L
    Shuichi Miyawaki
    Division of Hematology, Saiseikai Maebashi Hospital, Maebashi, Japan
    Cancer 104:2726-34. 2005
    ..Although intensive consolidation therapy has proven useful, the effectiveness of maintenance therapy remains controversial...
  6. doi request reprint Related transplantation with HLA-1 Ag mismatch in the GVH direction and HLA-8/8 allele-matched unrelated transplantation: a nationwide retrospective study
    Junya Kanda
    Division of Hematology, Saitama Medical Center, Jichi Medical University, Japan
    Blood 119:2409-16. 2012
    ..In particular, an HLA-B Ag mismatch in the GVH direction has an adverse effect on overall survival and treatment-related mortality in patients with standard-risk diseases...
  7. doi request reprint Leukemic infiltration of the lung following allogeneic hematopoietic stem cell transplantation
    Kazuhiko Kakihana
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Int J Hematol 89:118-22. 2009
    ..Thus, radiological and pathological corroborating assessment was important to reach the correct diagnosis...
  8. doi request reprint Clinical features of dasatinib-induced large granular lymphocytosis and pleural effusion
    Yasunobu Nagata
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Int J Hematol 91:799-807. 2010
    ..Moreover, the mean peak number of LGL was 9,215/microl, which was much higher than the mean peak number (4,635/microl) of LGL in patients without PE. These results may suggest possible association of both events in our cohorts...
  9. doi request reprint Intracranial hemorrhage following allogeneic hematopoietic stem cell transplantation
    Yuho Najima
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo 113 8677, Japan
    Am J Hematol 84:298-301. 2009
    ..A multivariate analysis with logistic regression identified acute GVHD as the only factor that significantly influenced ICH occurrence...
  10. doi request reprint Correlation between survival and number of mobilized CD34+ cells in patients with multiple myeloma or Waldenström macroglobulinemia
    Kazuhiko Kakihana
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Disease Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo 113 8677, Japan
    Pathol Oncol Res 16:583-7. 2010
    ..201) or survival after relapse (P = 0.330). In conclusion, our retrospective study could not find any correlation between survival and number of mobilized CD34+ cells, in contrast to previously reported results...
  11. ncbi request reprint Incapacitating lower limb pain syndrome in cord blood stem cell transplant recipients with calcineurin inhibitor
    Aiko Kida
    Hematology Division, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    Pathol Oncol Res 10:204-6. 2004
    ..We report herein two cases of lower limb pain syndrome, with some clinical features resembling CIPS, occurring during the early phase of cord blood stem cell transplantation for hematological malignancy...
  12. doi request reprint Cystatin C level as a marker of renal function in allogeneic hematopoietic stem cell transplantation
    Hideharu Muto
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo 113 8677, Japan
    Int J Hematol 91:471-7. 2010
    ..682, P < 0.001). Cystatin C measurement could provide a useful clinical tool to identify hematopoietic stem cell transplantation recipients at an increased risk for CKD...
  13. pmc Clinical utility of high-flow nasal cannula oxygen therapy for acute respiratory failure in patients with hematological disease
    Kaito Harada
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Disease Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677 Japan
    Springerplus 5:512. 2016
    ..Multivariate analysis showed that the cause of ARF (pneumonia, odds ratio 11.2, 95 % CI 1.76-71.5, p = 0.01) was the only risk factor for treatment failure. ..
  14. doi request reprint A case-control study of bronchiolitis obliterans syndrome following allogeneic hematopoietic stem cell transplantation
    Hideki Nakasone
    Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan
    Transpl Int 26:631-9. 2013
    ..53, P < 0.001). Prospective studies are required to elucidate the risk factors for the development of BOS, and future investigations should focus on finding a prophylactic approach against BOS based on these findings...
  15. doi request reprint Impact of hepatitis C virus infection on clinical outcome in recipients after allogeneic hematopoietic cell transplantation
    Hideki Nakasone
    Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan
    Am J Hematol 88:477-84. 2013
    ..Careful evaluation before embarking on HCT and intensive assessment against complications are warranted in HCV-infected recipients...
  16. doi request reprint Clinical impact of pre-transplant pulmonary impairment on survival after allogeneic hematopoietic stem cell transplantation
    Kazuhiko Kakihana
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Honkomagome, Bunkyo ku, Japan
    Pathol Oncol Res 18:11-6. 2012
    ..835). Our results suggest that allogeneic HSCT is safe for patients with pulmonary impairment. The lower frequency of fatal pulmonary complications after HSCT and the RIC regimen might contribute to favorable survival rates...
  17. ncbi request reprint Meningeal hematopoiesis following radiation myelitis in a hematopoietic stem-cell transplant recipient
    Miwa Sakai
    Hematology Division, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    Am J Hematol 79:291-3. 2005
    ..Because the patient was not in a disease state known to cause EMH, it is tempting to speculate that radiation-related neural injuries might cause donor cells to migrate to the central nervous system...
  18. ncbi request reprint Low-dose cyclosporin A with short-term methotrexate for graft-versus-host disease prophylaxis in allogeneic bone marrow transplantation from human leukocyte antigen-identical siblings: a prospective phase II study in Japanese patients
    Akio Kohno
    Division of Hematology, JA Aichi Showa Hospital, Konan, Aichi, Japan
    Int J Hematol 84:83-9. 2006
    ..A prospective randomized study is required to determine whether low-dose or standard-dose CSP in combination with MTX is optimal for Japanese patients who undergo allogeneic BMT from HLA-identical siblings...
  19. doi request reprint Central nervous system relapse of leukemia after allogeneic hematopoietic stem cell transplantation
    Kumi Oshima
    Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan
    Biol Blood Marrow Transplant 14:1100-7. 2008
    ..Although the outcome of patients with CNS relapse was generally poor, long-term disease-free survival could be achieved in some patients...
  20. doi request reprint Clinical impact of hematogones on outcomes of allogeneic hematopoietic stem cell transplantation
    Noriko Doki
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Ann Hematol 94:2055-60. 2015
    ..The emergence of HGs at day 30 among patients undergoing BMT may be a very useful indicator of subsequent survival outcomes or acute GVHD in common clinical practice. ..
  21. doi request reprint The predictive value for pulmonary infection by area over the neutrophil curve (D-index) in patients who underwent reduced intensity hematopoietic stem cell transplantation
    Jun Aoki
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Pathol Oncol Res 20:879-83. 2014
    ..11000) with comparable sensitivity and specificity. Our results demonstrate that the D21-index, as well as the D-index, are useful tools for the prediction of pulmonary infection in RIST...
  22. doi request reprint Mikulicz's disease with severe thrombocytopenia following autologous stem cell transplantation in a multiple myeloma patient
    Chihiro Sakurai
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo 113 8677, Japan
    Int J Hematol 90:532-6. 2009
    ..No apparent signs of MM recurrence were documented during these clinical events...
  23. doi request reprint Safe switching from dasatinib to nilotinib after a 1-month off-drug period for persistent pleural effusion in patients with chronic myelogenous leukemia in chronic phase
    Yasunobu Nagata
    Hematology Division, Tokyo Metropolitan Komagome Hospital, 3 18 22 Honkomagome, Bunkyo, Tokyo 113 8677, Japan
    Int J Hematol 91:539-41. 2010
    ..The lymphocytosis and increased large granular lymphocyte count observed during dasatinib treatment also subsided after switching medications...
  24. doi request reprint Clinical features of adult acute leukemia with 11q23 abnormalities in Japan: a co-operative multicenter study
    Hayato Tamai
    Department of Hematology, Nippon Medical School, Sendagi 1 1 5, Bunkyo ku, Tokyo, Japan
    Int J Hematol 87:195-202. 2008
    ..However, further studies involving a large number of cases are required to assess the effect of allo-HSCT on adult AL with 11q23 abnormalities...
  25. doi request reprint The clinical features of fatal cyclophosphamide-induced cardiotoxicity in a conditioning regimen for allogeneic hematopoietic stem cell transplantation (allo-HSCT)
    Shinya Ishida
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Ann Hematol 95:1145-50. 2016
    ..In summary, fatal CY cardiotoxicity with allo-HSCT is a rare complication, but it is associated with high mortality. The possibility of CY-induced cardiotoxicity must be considered early after the administration of CY. ..
  26. pmc Graft-versus-Host Disease after HLA-Matched Sibling Bone Marrow or Peripheral Blood Stem Cell Transplantation: Comparison of North American Caucasian and Japanese Populations
    Junya Kanda
    Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan
    Biol Blood Marrow Transplant 22:744-51. 2016
    ..In conclusion, our data indicate that irrespective of graft source, the risk of severe acute GVHD is lower in Japanese patients, resulting in a lower risk of nonrelapse mortality. ..
  27. doi request reprint Eight-year follow-up of patients with immune thrombocytopenic purpura related toH. pyloriinfection
    Taku Kikuchi
    Hematology Division, Tokyo Metropolitan Komagome Hospital, Komagome Hospital, Honkomagome, Bunkyo, Tokyo, Japan
    Platelets 22:61-4. 2011
    ..Two of 13 patients re-examined by UBIT showed positive results and one of these two patients continued to keep normal platelet count. Nonetheless, the prognosis of patients who responded to eradication was excellent...
  28. ncbi request reprint Frequent exacerbation of pulmonary nocardiosis during maintenance antibiotic therapies in a hematopoietic stem cell transplant recipient
    Kazuhiko Kakihana
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, Japan
    Int J Hematol 86:455-8. 2007
    ..Frequent exacerbation of PN was considered to have resulted from the low blood concentration of these antibiotics, and decreased gastrointestinal absorption, probably due to cGVHD, might have been the underlying problem...
  29. ncbi request reprint Renal dysfunction after total-body irradiation. Significance of selective renal shielding blocks
    Hiroshi Igaki
    Department of Radiation Oncology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    Strahlenther Onkol 181:704-8. 2005
    ..Also studied was the risk of renal dysfunction after TBI/BMT with or without the use of selective renal shielding blocks...
  30. doi request reprint Gastric Antral Vascular Ectasia during the Treatment of Chronic Myelogenous Leukemia with Imatinib Mesylate
    Kensuke Narukawa
    Division of Hematology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Japan
    Intern Med 55:69-72. 2016
    ..Although the precise mechanism of IM-GAVE is not understood, all patients took at least 400 mg/day of IM at the onset of GAVE. Thus, higher doses of IM (≥400 mg/day) may be a risk factor for IM-GAVE. ..
  31. doi request reprint Impact of prior azacitidine on the outcome of allogeneic hematopoietic transplantation for myelodysplastic syndrome
    Gaku Oshikawa
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Pathol Oncol Res 21:1037-43. 2015
    ..Acute graft-versus-host disease rates were similar between the two groups. These results should be reassuring to patients with high-risk MDS receiving AZA before allo-HSCT...
  32. doi request reprint Delayed hematological recovery following autologous transplantation utilizing peripheral blood stem cells harvested after treatment with arsenic trioxide
    Toshimitsu Ueki
    Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Bunkyo ku, Tokyo, 113 8677, Japan
    Pathol Oncol Res 14:387-90. 2008
    ..Our observations highlight the need for study of the real effects of As(2)O(3) on the kinetics of normal hematopoietic engraftment following auto-PBSCT...
  33. doi request reprint Erythrocytosis caused by erythropoietin-producing thymic carcinoma
    Wataru Munakata
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo 113 8677, Japan
    Int J Clin Oncol 15:220-3. 2010
    ..The existence of EPO was confirmed immunohistochemically using the tumor tissue. Postoperative clinical improvement of erythrocytosis and the decline of EPO suggest a paraneoplastic nature of erythrocytosis as seen in this patient...
  34. ncbi request reprint A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis
    Yujiro Kida
    Department of Internal Medicine, Division of Nephrology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    Ther Apher Dial 11:402-6. 2007
    ..The patient's clinical course would suggest that TTP post mini-alloPBSCT could be treated with PE in some cases, despite the development of dialysis-requiring severe ARF being a poor prognostic factor...
  35. ncbi request reprint Comparison of transplant outcomes and economic costs between biosimilar and originator filgrastim in allogeneic hematopoietic stem cell transplantation
    Kaito Harada
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Disease Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Int J Hematol 104:709-719. 2016
    ..Although BF significantly reduced filgrastim costs in both BMT and PBSCT, total hospitalization costs were not significantly different between BF and OF...
  36. doi request reprint Clinical outcome of hematopoietic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL): experience from a single institution
    Noriko Doki
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Pathol Oncol Res 20:61-6. 2014
    ..Imatinib administration given before allo-HSCT was not associated with favorable outcome. Second-generation tyrosine kinase inhibitors may be more suitable candidates for Ph + ALL before and after allo-HSCT...
  37. doi request reprint Serial monitoring of T315I BCR-ABL mutation by Invader assay combined with RT-PCR
    Masahide Yamamoto
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo 113 8677, Japan
    Int J Hematol 89:482-8. 2009
    ..8% at relapse). Thus, our new approach could be a useful tool to study the kinetics of mutant clones and the pharmacokinetics of drug resistance with regard to the T315I mutation...
  38. ncbi request reprint [Immunosuppressive-associated encephalopathy in bone marrow transplant recipients]
    Keiko Ohta
    Department of Neurology, Tokyo Metropolitan Komagome Hospital, 3 18 22 Honkomagome, Bunkyo, Tokyo 113 8677, Japan
    No To Shinkei 56:395-401. 2004
    ..5 of 7 cases in SAA and MDS had taken cyclosporine as treatment of the disease before bone marrow transplantation and that might influence the incidence of encephalopathy...
  39. doi request reprint Central Nervous System Involvement at the Time of Allogeneic Hematopoietic Stem Cell Transplantation Is Associated with a Poor Outcome in Patients with Acute Myeloid Leukemia
    Shuntaro Ikegawa
    Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3 18 22 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    Pathol Oncol Res . 2016
    ..27; 95% CI 0.53-2.07; p = 0.6). Early diagnosis and eradication of CNS+ at the time of allo-HSCT may be necessary to improve the outcome for patients with CNS+ AML...
  40. doi request reprint The role of hematopoietic stem cell transplantation for relapsed and refractory Hodgkin lymphoma
    Shinichi Kako
    Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan
    Am J Hematol 90:132-8. 2015
    ..Allogeneic HSCT might be beneficial even to relapsed HL after autologous HSCT, although establishing the role of allogeneic HSCT remains a challenge...
  41. ncbi request reprint [The role of gemtuzumab ozogamicin in the treatment of acute myeloid leukemia patients]
    Hisashi Sakamaki
    Tokyo Metropolitan Komagome Hospital, Bunkyo ku, Tokyo, Japan
    Gan To Kagaku Ryoho 35:1629-34. 2008
    ..In order to reduce toxicity and improve efficacy, its optimal dose and schedule should be defined by large clinical trials...
  42. doi request reprint Kinetics of peripheral hepatitis B virus-specific CD8+ T cells in patients with onset of viral reactivation
    Jun Aoki
    Division of Hematology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, 18 22 3 Honkomagome, Bunkyo ku, Tokyo, 113 8677, Japan
    J Gastroenterol 48:728-37. 2013
    ..However, it remains unclear how liver disease develops after HBV reactivation. To compare the host immune response against HBV, we performed immunological analyses of six HBV reactivation patients...
  43. ncbi request reprint Calcineurin-inhibitor pain syndrome following haematopoietic stem cell transplantation
    Aiko Kida
    Hematology Division, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    Br J Haematol 126:288. 2004
  44. doi request reprint Prognostic significance of WT1 mRNA and anti-WT1 antibody levels in peripheral blood in patients with myelodysplastic syndromes
    Hideto Tamura
    Division of Hematology, Department of Medicine, Nippon Medical School, 1 1 5, Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Leuk Res 34:986-90. 2010
    ..Moreover, high values of anti-WT1 antibody were an independent predictor of longer survival. These data may justify therapeutic strategies targeting WT1 molecules in MDS...