Kazutaka Saito

Summary

Affiliation: Tokyo Medical and Dental University
Country: Japan

Publications

  1. ncbi request reprint The impact of preoperative serum C-reactive protein on the prognosis of patients with upper urinary tract urothelial carcinoma treated surgically
    Kazutaka Saito
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    BJU Int 100:269-73. 2007
  2. ncbi request reprint External validation of TNM-C score in three community hospital cohorts for clear cell renal cell carcinoma
    Takayuki Nakayama
    Department of Urology, Tokyo Medical and Dental University Graduate School, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Anticancer Res 34:921-6. 2014
  3. doi request reprint Role of C-reactive protein in urological cancers: a useful biomarker for predicting outcomes
    Kazutaka Saito
    Department of Urology, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 20:161-71. 2013
  4. doi request reprint Impact of C-reactive protein kinetics on survival of patients with advanced urothelial carcinoma treated by second-line chemotherapy with gemcitabine, etoposide and cisplatin
    Kazutaka Saito
    Department of Urology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan
    BJU Int 110:1478-84. 2012
  5. doi request reprint C-reactive protein as a biomarker for urological cancers
    Kazutaka Saito
    Department of Urology, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Nat Rev Urol 8:659-66. 2011
  6. ncbi request reprint Spatial and isoform specific p63 expression in the male human urogenital tract
    Kazutaka Saito
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 176:2268-73. 2006
  7. doi request reprint Role of C-reactive protein as a biomarker for renal cell carcinoma
    Kazutaka Saito
    Department of Urology, Tokyo Medical and Dental University, Bunkyo ku, Japan
    Expert Rev Anticancer Ther 10:1979-89. 2010
  8. doi request reprint Impact of C-reactive protein kinetics on survival of patients with metastatic renal cell carcinoma
    Kazutaka Saito
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    Eur Urol 55:1145-53. 2009
  9. doi request reprint External validation of the Mayo Clinic cancer specific survival score in a Japanese series of clear cell renal cell carcinoma
    Yasuhisa Fujii
    Department of Urology and Human Pathology, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 180:1290-5; discussion 1295-6. 2008
  10. doi request reprint Diabetes mellitus with obesity is a predictor of recurrence in patients with non-metastatic renal cell carcinoma
    Hiroshi Fukushima
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Jpn J Clin Oncol 43:740-6. 2013

Detail Information

Publications82

  1. ncbi request reprint The impact of preoperative serum C-reactive protein on the prognosis of patients with upper urinary tract urothelial carcinoma treated surgically
    Kazutaka Saito
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    BJU Int 100:269-73. 2007
    ....
  2. ncbi request reprint External validation of TNM-C score in three community hospital cohorts for clear cell renal cell carcinoma
    Takayuki Nakayama
    Department of Urology, Tokyo Medical and Dental University Graduate School, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Anticancer Res 34:921-6. 2014
    ....
  3. doi request reprint Role of C-reactive protein in urological cancers: a useful biomarker for predicting outcomes
    Kazutaka Saito
    Department of Urology, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 20:161-71. 2013
    ..This review discusses the importance of C-reactive protein as a prognostic biomarker in urological cancers on the basis of the currently available evidence...
  4. doi request reprint Impact of C-reactive protein kinetics on survival of patients with advanced urothelial carcinoma treated by second-line chemotherapy with gemcitabine, etoposide and cisplatin
    Kazutaka Saito
    Department of Urology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan
    BJU Int 110:1478-84. 2012
    ....
  5. doi request reprint C-reactive protein as a biomarker for urological cancers
    Kazutaka Saito
    Department of Urology, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Nat Rev Urol 8:659-66. 2011
    ..CRP could, therefore, be an important biomarker for urological cancers...
  6. ncbi request reprint Spatial and isoform specific p63 expression in the male human urogenital tract
    Kazutaka Saito
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 176:2268-73. 2006
    ..To determine the possible roles of p63 in the male human urogenital tract its expression was systematically examined...
  7. doi request reprint Role of C-reactive protein as a biomarker for renal cell carcinoma
    Kazutaka Saito
    Department of Urology, Tokyo Medical and Dental University, Bunkyo ku, Japan
    Expert Rev Anticancer Ther 10:1979-89. 2010
    ..Therefore, dynamic changes of CRP concentration could indicate clinical pharmacologic response to therapeutic intervention. Taken together, we could conclude that CRP is a significant biomarker for renal cell carcinoma...
  8. doi request reprint Impact of C-reactive protein kinetics on survival of patients with metastatic renal cell carcinoma
    Kazutaka Saito
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    Eur Urol 55:1145-53. 2009
    ..Pretreatment C-reactive protein (CRP) level has been shown to be prognostic for metastatic renal cell carcinoma (mRCC)...
  9. doi request reprint External validation of the Mayo Clinic cancer specific survival score in a Japanese series of clear cell renal cell carcinoma
    Yasuhisa Fujii
    Department of Urology and Human Pathology, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 180:1290-5; discussion 1295-6. 2008
    ..We validated the Mayo Clinic SSIGN (stage, size, grade and necrosis) score in an independent Japanese sample of patients...
  10. doi request reprint Diabetes mellitus with obesity is a predictor of recurrence in patients with non-metastatic renal cell carcinoma
    Hiroshi Fukushima
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Jpn J Clin Oncol 43:740-6. 2013
    ..To investigate the associations of diabetes mellitus with recurrence and prognosis after surgery for non-metastatic renal cell carcinoma and the effect modification of obesity on the above relationships...
  11. doi request reprint Role of diffusion-weighted magnetic resonance imaging in predicting sensitivity to chemoradiotherapy in muscle-invasive bladder cancer
    Soichiro Yoshida
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Int J Radiat Oncol Biol Phys 83:e21-7. 2012
    ..Diffusion-weighted MRI (DW-MRI) is a functional imaging technique that quantifies the diffusion of water molecules in a noninvasive manner. We investigated whether DW-MRI predicts CRT sensitivity of MIBC...
  12. doi request reprint Apparent diffusion coefficient as a prognostic biomarker of upper urinary tract cancer: a preliminary report
    Soichiro Yoshida
    Department of Urology, Tokyo Medical and Dental University Graduate School, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Eur Radiol 23:2206-14. 2013
    ..To investigate the role of apparent diffusion coefficient (ADC) as a biomarker reflecting the aggressiveness of upper urinary tract urothelial cell carcinoma (UUT-UCC)...
  13. doi request reprint Development, validation, and head-to-head comparison of logistic regression-based nomograms and artificial neural network models predicting prostate cancer on initial extended biopsy
    Satoru Kawakami
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Eur Urol 54:601-11. 2008
    ..Using cohorts examined by extended biopsy, we developed and validated multivariate models predicting prostate cancer on initial biopsy and examined whether these extended biopsy-based models outperform previously established models...
  14. ncbi request reprint Loss of uroplakin III expression is associated with a poor prognosis in patients with urothelial carcinoma of the upper urinary tract
    Yukihiro Ohtsuka
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    BJU Int 97:1322-6. 2006
    ....
  15. doi request reprint Impact of lower urinary tract symptoms on prostate cancer risk among Japanese men with prostate-specific antigen <10 ng/mL and non-suspicious digital rectal examination
    Masaya Ito
    Department of Urology, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 20:1163-8. 2013
    ..To investigate the association between lower urinary tract symptoms status and prostate cancer risk at initial extended biopsy...
  16. doi request reprint Combination of diffusion-weighted magnetic resonance imaging and extended prostate biopsy predicts lobes without significant cancer: application in patient selection for hemiablative focal therapy
    Yoh Matsuoka
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan Electronic address
    Eur Urol 65:186-92. 2014
    ..However, extended PBx, a common diagnostic procedure, has a limited predictive ability for lobes without significant cancer...
  17. ncbi request reprint Lymphovascular invasion is independently associated with poor prognosis in patients with localized upper urinary tract urothelial carcinoma treated surgically
    Kazutaka Saito
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 178:2291-6; discussion 2296. 2007
    ..We explored the prognostic impact of lymphovascular invasion in patients with localized upper urinary tract urothelial carcinoma...
  18. doi request reprint Performance of prostate-specific antigen mass in estimation of prostate volume in Japanese men with benign prostate hyperplasia
    Hitoshi Masuda
    Department of Urology, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 19:929-35. 2012
    ....
  19. doi request reprint History of malignancy is a predictor of prostate cancer detection: incorporation into a pre-biopsy nomogram
    Satoru Kawakami
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 15:1055-60. 2008
    ....
  20. ncbi request reprint [Successful long-term management of hepatic and lymph nodes metastases of ureteral cancer by multimodal treatment including radiofrequency ablation]
    Yosuke Yasuda
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo
    Nihon Hinyokika Gakkai Zasshi 101:758-63. 2010
    ..The patient underwent RFA again followed by GC chemotherapy and then all hepatic metastases have not revealed enlargement. More than three years after surgery, the patient has achieved a high quality of life...
  21. doi request reprint C-reactive protein level predicts prognosis in patients with muscle-invasive bladder cancer treated with chemoradiotherapy
    Soichiro Yoshida
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    BJU Int 101:978-81. 2008
    ....
  22. doi request reprint High diagnostic ability of multiparametric magnetic resonance imaging to detect anterior prostate cancer missed by transrectal 12-core biopsy
    Yoshinobu Komai
    Department of Urology, Graduate School, Tokyo Medical and Dental University and Department of Radiology, Ochanomizu Surugadai Clinic CI, Tokyo, Japan
    J Urol 190:867-73. 2013
    ....
  23. doi request reprint Impact of advanced age on biochemical recurrence after radical prostatectomy in Japanese men according to pathological stage
    Hitoshi Masuda
    Department of Urology, Tokyo Medical and Dental University Graduate School, Bunkyo ku, Tokyo, Japan
    Jpn J Clin Oncol 43:410-6. 2013
    ..To determine the impact of advanced age as a predictor of biochemical recurrence after radical prostatectomy in Japanese patients with regard to pathological stage...
  24. doi request reprint Extended biopsy based criteria incorporating cumulative cancer length for predicting clinically insignificant prostate cancer
    Yoshinobu Komai
    Department of Urology, Tokyo Medical and Dental University Graduate, Tokyo, Japan
    BJU Int 110:E564-9. 2012
    ..The present study has added new criteria for predicting insignificant prostate cancer, which would lead to a better selection of candidates for AS...
  25. doi request reprint Antimicrobial prophylaxis is not necessary in clean category minimally invasive surgery for renal and adrenal tumors: a prospective study of 373 consecutive patients
    Toshiki Kijima
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Urology 80:570-5. 2012
    ..To assess the feasibility of the nonuse of antimicrobial prophylaxis (AMP) on the incidence of infectious complications after clean category minimally invasive surgery for renal and adrenal tumors...
  26. doi request reprint Favourable outcomes of patients with clinical stage T3N0M0 bladder cancer treated with induction low-dose chemo-radiotherapy plus partial or radical cystectomy vs immediate radical cystectomy: a single-institutional retrospective comparative study
    Fumitaka Koga
    Department of Urology, Tokyo Medical and Dental University, Graduate School, Tokyo, Japan
    BJU Int 104:189-94. 2009
    ....
  27. doi request reprint Prognostic impact of postoperative C-reactive protein level in patients with metastatic renal cell carcinoma undergoing cytoreductive nephrectomy
    Manabu Tatokoro
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 180:515-9. 2008
    ..We explored the prognostic impact of C-reactive protein status in patients with metastatic renal cell carcinoma undergoing cytoreductive nephrectomy...
  28. doi request reprint Sensitivity to chemoradiation predicts development of metastasis in muscle-invasive bladder cancer patients
    Fumitaka Koga
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan Electronic address
    Urol Oncol 31:1270-5. 2013
    ..Since metastatic disease accounts for most bladder cancer deaths, we hypothesized that tumor sensitivity to chemoradiation may reflect metastatic potential in MIBC...
  29. pmc Successful reduction of hospital-acquired methicillin-resistant Staphylococcus aureus in a urology ward: a 10-year study
    Manabu Tatokoro
    Department of Urology, Tokyo Medical and Dental University Graduate School, 1 5 45 Yushima, Bunkyo, Tokyo 113 8519, Japan
    BMC Urol 13:35. 2013
    ....
  30. pmc A novel equation and nomogram including body weight for estimating prostate volumes in men with biopsy-proven benign prostatic hyperplasia
    Yasukazu Nakanishi
    Department of Urology, Tokyo Medical and Dental University, Tokyo 113 8519, Japan
    Asian J Androl 14:703-7. 2012
    ..764. Calibration plots showed good agreement between predicted probability and observed proportion. In conclusion, TPV can be easily estimated using these four independent predictors...
  31. ncbi request reprint Favorable outcome of preoperative low dose chemoradiotherapy against muscle-invasive bladder cancer
    Yukio Kageyama
    Department of Urology and Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Am J Clin Oncol 26:504-7. 2003
    ..Low-dose chemoradiotherapy is as effective as other neoadjuvant protocols and is applicable to high-risk patients. The bladder can be preserved by partial cystectomy in selected cases with clinical complete regression...
  32. ncbi request reprint [Use of diffusion-weighted MRI in monitoring response of lymph node metastatic bladder cancer treated with chemotherary]
    Takayuki Nakayama
    The Department of Urology, Graduate School, Tokyo Medical and Dental University
    Nihon Hinyokika Gakkai Zasshi 99:737-41. 2008
    ..These signal changes were consistent with the change of morphological images (CT, MRI (T1-W, T2-W)), 18F-FDG PET and tumor markers. This case suggests that DW-MRI is useful in monitoring treatment response of metastatic bladder cancer...
  33. doi request reprint Diagnostic performance of diffusion-weighted magnetic resonance imaging in bladder cancer: potential utility of apparent diffusion coefficient values as a biomarker to predict clinical aggressiveness
    Shuichiro Kobayashi
    Department of Urology, Tokyo Medical and Dental University Graduate School, Bunkyo ku, Tokyo, 113 8519, Japan
    Eur Radiol 21:2178-86. 2011
    ....
  34. doi request reprint Prostate-specific antigen response to deferred combined androgen blockade therapy using bicalutamide predicts survival after subsequent oestrogen and docetaxel therapies in patients with castration-resistant prostate cancer
    Toshiki Kijima
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    BJU Int 110:1149-55. 2012
    ..We propose that PSA response to deferred CAB be used for planning individualized treatment that includes secondary hormonal therapy and chemotherapy...
  35. doi request reprint Selective bladder-sparing protocol consisting of induction low-dose chemoradiotherapy plus partial cystectomy with pelvic lymph node dissection against muscle-invasive bladder cancer: oncological outcomes of the initial 46 patients
    Fumitaka Koga
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    BJU Int 109:860-6. 2012
    ....
  36. ncbi request reprint [Successful treatment with multidisciplinary therapy including low-dose chemoradiotherapy against metastatic recurrences of small cell carcinoma of the renal pelvis: a case report]
    Hiroshi Fukushima
    Department of Urology, Tokyo Medical and Dental University, Graduate School, Tokyo, Japan
    Nihon Hinyokika Gakkai Zasshi 102:638-43. 2011
    ..Low-dose chemoradiotherapy (sigma 40 Gy/20 Fr/29 d + cisplatin 10 mg/d for 2 d x 2) to these lesions successfully brought CR. She is alive without any evidence of disease at 3 years after total nephroureterectomy...
  37. doi request reprint Development and external validation of a new outcome prediction model for patients with clear cell renal cell carcinoma treated with nephrectomy based on preoperative serum C-reactive protein and TNM classification: the TNM-C score
    Yasumasa Iimura
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 181:1004-12; discussion 1012. 2009
    ..C-reactive protein has been shown to be a prognostic factor for renal cell carcinoma. We developed a new prediction model including C-reactive protein in patients with clear cell renal cell carcinoma...
  38. doi request reprint Low-dose chemoradiotherapy followed by partial or radical cystectomy against muscle-invasive bladder cancer: an intent-to-treat survival analysis
    Fumitaka Koga
    Department of Urology, Tokyo Medical and Dental University, Graduate School, Tokyo, Japan
    Urology 72:384-8. 2008
    ..To evaluate the clinical outcomes of patients with muscle-invasive bladder cancer treated with a prospective institutional protocol composed of induction low-dose chemoradiotherapy (LCRT) plus partial or radical cystectomy...
  39. ncbi request reprint Increased preoperative serum C-reactive protein level predicts a poor prognosis in patients with localized renal cell carcinoma
    Yoshinobu Komai
    Department of Urology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan
    BJU Int 99:77-80. 2007
    ..To evaluate the value of the preoperative serum C-reactive protein (CRP) level in the prognosis of patients with localized renal cell carcinoma (RCC)...
  40. doi request reprint Diagnostic performance of initial transperineal 14-core prostate biopsy to detect significant cancer
    Hideki Takeshita
    Department of Urology, Tokyo Medical and Dental University Graduate School, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Int Urol Nephrol 45:645-52. 2013
    ..To investigate cancers missed by extended transperineal (TP) 14-core biopsy (TP14PBx) and examined its diagnostic performance...
  41. doi request reprint Usefulness of pre-biopsy multiparametric magnetic resonance imaging and clinical variables to reduce initial prostate biopsy in men with suspected clinically localized prostate cancer
    Noboru Numao
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    J Urol 190:502-8. 2013
    ..We evaluated the usefulness of pre-biopsy multiparametric magnetic resonance imaging and clinical variables to decrease initial prostate biopsies...
  42. doi request reprint Incidence of benign pathologic lesions at partial nephrectomy for presumed RCC renal masses: Japanese dual-center experience with 176 consecutive patients
    Yasuhisa Fujii
    Department of Urology and Pathology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan
    Urology 72:598-602. 2008
    ..To determine the incidence of benign pathologic findings at elective partial nephrectomy for renal masses thought to be renal cell carcinoma (RCC) on preoperative imaging in Japanese patients...
  43. doi request reprint Effect of diabetes mellitus on high-grade prostate cancer detection among Japanese obese patients with prostate-specific antigen less than 10 ng/mL
    Hiroshi Fukushima
    Department of Urology, Tokyo Medical and Dental University, Graduate School, Tokyo, Japan
    Urology 79:1329-34. 2012
    ..To investigate the association of diabetes mellitus (DM) with prostate cancer (PCa) risk and grade among Japanese patients undergoing extended biopsy and to investigate how obesity modifies these relationships...
  44. doi request reprint Pathology-based risk stratification of muscle-invasive bladder cancer patients undergoing cystectomy for persistent disease after induction chemoradiotherapy in bladder-sparing approaches
    Fumitaka Koga
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    BJU Int 110:E203-8. 2012
    ....
  45. doi request reprint Perioperative complications of radical cystectomy after induction chemoradiotherapy in bladder-sparing protocol against muscle-invasive bladder cancer: a single institutional retrospective comparative study with primary radical cystectomy
    Aki Iwai
    Department of Urology, Tokyo Medical and Dental University Graduate School, Yushima, Tokyo 113 8519, Japan
    Jpn J Clin Oncol 41:1373-9. 2011
    ..To compare rates of early morbidity after radical cystectomy in patients treated with or without induction chemoradiotherapy (CRT) using a standardized reporting methodology...
  46. doi request reprint Diffusion-weighted magnetic resonance imaging in the differentiation of angiomyolipoma with minimal fat from clear cell renal cell carcinoma
    Hajime Tanaka
    Department of Urology, Tokyo Medical and Dental University Graduate School, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Int J Urol 18:727-30. 2011
    ..The standard deviations of the ADC values were significantly smaller for MFAML than for CCRCC (P = 0.0015). In conclusion, DW-MRI can be considered a useful and noninvasive addition to the preoperative differentiation of CCRCC and MFAML...
  47. doi request reprint Young age as favorable prognostic factor for cancer-specific survival in localized renal cell carcinoma
    Yoshinobu Komai
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Urology 77:842-7. 2011
    ..To evaluate the prognostic effect of age in patients with localized renal cell carcinoma (RCC) and investigate the incidence of Xp11 translocation RCC in young patients who developed recurrence...
  48. doi request reprint Oncological outcome of minimum incision endoscopic radical nephrectomy for pathologically organ confined renal cell carcinoma
    Yasumasa Iimura
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 15:44-7. 2008
    ..To evaluate the oncological outcome of the patients with pathologically organ confined (pT1-2N0M0) RCC treated with this operation, the results in those patients were analyzed...
  49. ncbi request reprint Endoscopic minilaparotomy partial nephrectomy for solitary renal cell carcinoma smaller than 4 cm
    Yukio Kageyama
    Department of Urology and Reproductive Medicine, Graduate School Tokyo Medical and Dental University, Tokyo, Japan
    Jpn J Clin Oncol 32:417-21. 2002
    ..For small, incidentally discovered renal cell carcinoma, partial nephrectomy is becoming more widely accepted as an alternative to radical nephrectomy and the need for minimally invasive approach is increasing...
  50. ncbi request reprint Prognostic significance of endothelial Per-Arnt-sim domain protein 1/hypoxia-inducible factor-2alpha expression in a subset of tumor associated macrophages in invasive bladder cancer
    Fumitaka Koga
    Department of Urology and Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 171:1080-4. 2004
    ..Recent studies showed that EPAS1 is expressed in tumor associated macrophages (TAMs), which have multifaceted roles in tumor progression. We hypothesized that EPAS1 expressed in TAMs may contribute to bladder cancer progression...
  51. doi request reprint Phase-II trial of combination treatment of interferon-α, cimetidine, cyclooxygenase-2 inhibitor and renin-angiotensin-system inhibitor (I-CCA therapy) for advanced renal cell carcinoma
    Manabu Tatokoro
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Cancer Sci 102:137-43. 2011
    ..Grade 3/4 toxicities were never observed. The I-CCA therapy, providing favorable responses and low toxicity profiles, is worthy of further consideration as a first-line therapy for metastatic RCC...
  52. doi request reprint Initial experience of diffusion-weighted magnetic resonance imaging to assess therapeutic response to induction chemoradiotherapy against muscle-invasive bladder cancer
    Soichiro Yoshida
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Urology 75:387-91. 2010
    ..However, conventional imaging studies are not useful in evaluating therapeutic response because of their inability to distinguish residual cancer from changes secondary to the treatment...
  53. doi request reprint A novel repeat biopsy nomogram based on three-dimensional extended biopsy
    Mizuaki Sakura
    Department of Urology, Tokyo Medical and Dental University, Graduate School, Tokyo, Japan
    Urology 77:915-20. 2011
    ..To develop a nomogram based on a cohort examined with 3-dimensional (3D) protocol for diagnosis of prostate cancer on repeat biopsy...
  54. doi request reprint Three-dimensional 26-core biopsy-based patient selection criteria for nerve-sparing radical prostatectomy
    Noboru Numao
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 15:1061-6. 2008
    ..In the current study, we developed patient selection criteria for nerve-sparing RP based on the three-dimensional 26-core (3D26) biopsy-derived variables...
  55. ncbi request reprint Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder
    Fumitaka Koga
    Department of Urology and Reproductive Medicine, Tokyo Medical and Dental University, Tokyo, Japan
    Clin Cancer Res 9:5501-7. 2003
    ..Uroplakin (UP) III expression was also evaluated to investigate a possible association between loss of p63 expression and terminal urothelial differentiation...
  56. ncbi request reprint [Primary adenocarcinoma of the female urethra treated by multimodal therapy]
    Hajime Tanaka
    Department of Urology, Tokyo Medical and Dental University
    Hinyokika Kiyo 55:43-6. 2009
    ..No metastasis was found in the lymph nodes. The final diagnosis was urethral adenocarcinoma, pT4N0, Stage IV. Five months after surgery, local recurrence and distant metastases appeared, and she died 14 months after surgery...
  57. doi request reprint Discarding antimicrobial prophylaxis for transurethral resection of bladder tumor: a feasibility study
    Minato Yokoyama
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 16:61-3. 2009
    ..To evaluate the feasibility of discarding antimicrobial prophylaxis (AMP) for transurethral resection of bladder tumor (TURBT)...
  58. doi request reprint Favorable response to combination treatment of cimetidine, cyclooxygenase-2 inhibitor and renin-angiotensin system inhibitor in metastatic renal cell carcinoma: Report of three cases
    Manabu Tatokoro
    Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 15:848-50. 2008
    ..Pulmonary metastases showed partial remission for 31 months. The CCA therapy could be an alternative treatment for metastatic RCC patients unfit for cytokine therapy...
  59. doi request reprint Prognostic impact of pretreatment C-reactive protein for patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors
    Yosuke Yasuda
    Department of Urology, Cancer Institute Hospital of Japanese Foundation For Cancer Research, 3 8 31 Ariake, Koto ku, Tokyo, 135 8550, Japan
    Int J Clin Oncol 18:884-9. 2013
    ..Therefore, we further evaluated the prognostic impact of CRP for patients with metastatic renal cell carcinoma treated with molecular-targeted agents of tyrosine kinase inhibitors...
  60. doi request reprint Prognostic impact of C-reactive protein for determining overall survival of patients with castration-resistant prostate cancer treated with docetaxel
    Masaya Ito
    Department of Urology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan
    Urology 78:1131-5. 2011
    ..To verify the prognostic impact of C-reactive protein (CRP) for patients with castration-resistant prostate cancer (CRPC) treated with docetaxel in a single institution...
  61. doi request reprint Characteristics and clinical significance of prostate cancers missed by initial transrectal 12-core biopsy
    Noboru Numao
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    BJU Int 109:665-71. 2012
    ..To characterize prostate cancers missed by initial transrectal 12-core biopsy...
  62. doi request reprint Female urethral diverticular abscess clearly depicted by diffusion-weighted magnetic resonance imaging
    Soichiro Yoshida
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 15:460-1. 2008
    ..The low apparent diffusion coefficient value of the diverticulum indicated high viscosity restricting water diffusion. DW MRI could depict urethral diverticular abscess clearly and easily in a non-invasive manner...
  63. ncbi request reprint Increased expression of sialyl-Lewis A correlates with poor survival in upper urinary tract urothelial cancer patients
    Kazutaka Saito
    Department of Urology and Reproductive Medicine, Tokyo Medical and Dental University Graduate School, 1 5 45, Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Anticancer Res 23:3441-6. 2003
    ..The present study was undertaken to determine whether these antigens could serve as prognostic parameters...
  64. doi request reprint Longitudinal change in renal function after radical nephrectomy in Japanese patients with renal cortical tumors
    Minato Yokoyama
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    J Urol 185:2066-71. 2011
    ..We investigated the longitudinal change in renal function after radical nephrectomy in Japanese patients with renal cortical tumors and compared it with that after partial nephrectomy...
  65. doi request reprint Impact of bladder neck involvement on progression in patients with primary non-muscle invasive bladder cancer: a prospective validation study
    Shuichiro Kobayashi
    Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan
    Urol Oncol 32:38.e29-36. 2014
    ..We prospectively validated BNI as a significant predictor for progression using a new cohort of patients with primary NMIBC...
  66. doi request reprint Collecting duct carcinoma with acquired cystic disease of the kidney in a long-term hemodialysis patient
    Mizuaki Sakura
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 15:93-5. 2008
    ..Three months later, left nephrectomy was performed because left RCC was suspected during CT. The histological diagnosis was multiple clear cell carcinomas. Peritonitis carcinomatosa appeared and the patient died 13 months later...
  67. doi request reprint Safety of transperineal 14-core systematic prostate biopsy in diabetic men
    Masahito Suzuki
    Department of Urology, Tokyo Medical and Dental University, Graduate School, Tokyo, Japan
    Int J Urol 16:930-5. 2009
    ..To examine whether the transrectal ultrasound-guided transperineal 14-core prostate biopsy can be carried out safely in diabetic men and to determine adequate antimicrobial prophylaxis protocol in this setting...
  68. ncbi request reprint [A case of fibroepithelial ureteral polyp in an adult patient]
    Shuichiro Kobayashi
    Department of Urology and Reproductive Medicine, Graduate School, Tokyo Medical and Dental University
    Hinyokika Kiyo 49:161-3. 2003
    ..Histological examination revealed that the villous tumor in the ureter was a fibroepithelial polyp...
  69. doi request reprint Treatment outcome and prognostic factors in renal cell cancer patients with bone metastasis
    Takeshi Yuasa
    Department of Urology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake, Koto ku, Tokyo, Japan
    Clin Exp Metastasis 28:405-11. 2011
    ..In this population, MSKCC scores were valid predictors of survival. With increased treatment options, RCC patients with bone metastasis may benefit further from subsequent modalities and/or agents...
  70. ncbi request reprint [Case of infective endocarditis diagnosed with renal infarction]
    Takayuki Nakayama
    The Department of Urology, Graduate School, Tokyo Medical and Dental University
    Nihon Hinyokika Gakkai Zasshi 100:504-7. 2009
    ..Therefore, the appropriate diagnosis of infective endocarditis is needed for patients with renal infarction without any other disorder causing renal infarction...
  71. doi request reprint New three-dimensional head-mounted display system, TMDU-S-3D system, for minimally invasive surgery application: procedures for gasless single-port radical nephrectomy
    Kazunori Kihara
    Department of Urology, Graduate School, School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 19:886-9. 2012
    ..Because of the potential benefits that this system offers, it deserves further refinements of its role in various minimally invasive surgeries...
  72. doi request reprint Interactions between inducible nitric oxide synthase and cyclooxygenase-2 in response to ischaemia-reperfusion of rabbit bladder
    Hitoshi Masuda
    Department of Urology, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan
    BJU Int 106:716-22. 2010
    ..To investigate the interactions between inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in response to ischaemia-reperfusion (I/R) of rabbit bladder...
  73. doi request reprint Initial experience of functional imaging of upper urinary tract neoplasm by diffusion-weighted magnetic resonance imaging
    Soichiro Yoshida
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 15:140-3. 2008
    ..We reported our initial experience of this imaging technique of upper urinary tract (UUT) urothelial carcinoma (UC)...
  74. ncbi request reprint Endoscope-assisted minilaparotomy (endoscopic minilaparotomy) for retroperitoneal Schwannoma: experience with three cases
    Yukio Kageyama
    Department of Urology and Reproductive Medicine, Graduate School Tokyo Medical and Dental University, Tokyo, Japan
    Jpn J Clin Oncol 32:177-80. 2002
    ..Wound pain was mild and full oral feeding and walk were resumed the day following operation. It is concluded that endoscopic minilaparotomy is applicable to retroperitoneal Schwannoma with excellent postoperative recovery...
  75. ncbi request reprint [A case of primary leiomyosarcoma of the spermatic cord]
    Soichiro Yoshida
    Department of Urology, Graduate School, Tokyo Medical and Dental University
    Nihon Hinyokika Gakkai Zasshi 95:718-21. 2004
    ..The pathological examination revealed leiomyosarcoma (3.6 x 2.7 x 1.0 cm, pT1bN0M0; 5th TNM, Stage IA; 5th AJCC). He is free of disease 3 year postoperatively...
  76. ncbi request reprint IFN gamma-induced up-regulation of PD-ECGF/TP enhances the cytotoxicity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in bladder cancer cells
    Gang Li
    Department of Urology and Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Yushima 1 5 45, Bunkyo ku, Tokyo 113 8519, Japan
    Anticancer Res 22:2607-12. 2002
    ..PD-ECGF/TP is an essential enzyme in converting 5'DFUR and 5FU to their active metabolites and can be up-regulated by some cytokines...
  77. ncbi request reprint [A comparative study assessing clinical effects of naftopidil and tamsulosin hydrochloride on benign prostatic hyperplasia]
    Tetsuo Hayashi
    Department of Urology and Reproductive Medicine, Graduate School, Tokyo Medical and Dental University
    Hinyokika Kiyo 48:7-11. 2002
    ..Tamsulosin hydrochloride was superior to naftopidil for the symptoms of urine flow and naftopidil was superior to tamsulosin hydrochloride for the symptom of nocturia...
  78. ncbi request reprint Localization of aquaporin-7 in human testis and ejaculated sperm: possible involvement in maintenance of sperm quality
    Kazutaka Saito
    Department of Urology and Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Urol 172:2073-6. 2004
    ..However, to our knowledge the spatial expression pattern and biological roles of AQP7 remain to be elucidated in humans...
  79. ncbi request reprint Malignant clear cell "sugar" tumor of the kidney: clear cell variant of epithelioid angiomyolipoma
    Kazutaka Saito
    Department of Urology, Nakano General Hospital, Japan
    J Urol 168:2533-4. 2002
  80. ncbi request reprint Reactive oxygen species mediate detrusor overactivity via sensitization of afferent pathway in the bladder of anaesthetized rats
    Hitoshi Masuda
    Department of Urology and Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    BJU Int 101:775-80. 2008
    ..g. ischaemia/reperfusion and inflammation) are characterized by the formation of ROS...
  81. ncbi request reprint Possible involvement of bone morphogenetic protein 2 in heterotopic ossification in metastatic lesion from urothelial carcinoma of bladder
    Yoshinobu Komai
    Department of Urology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan
    Int J Urol 13:1126-8. 2006
    ..The heterotopic ossification may result from the metaplasia of pluripotent stem cells into osteoblast cells induced by BMP-2 in a paracrine fashion...
  82. ncbi request reprint [Clinical study of surgical site infection following portless endoscopic urological surgery (PLES)]
    Manabu Tadokoro
    Department of Urology and Reproductive Medicine, Graduate School Tokyo Medical and Dental University
    Hinyokika Kiyo 49:721-5. 2003
    ....