Keisuke Nakamura

Summary

Affiliation: Tohoku University
Country: Japan

Publications

  1. ncbi request reprint Zirconia as a dental implant abutment material: a systematic review
    Keisuke Nakamura
    New Industry Creation Hatchery Center, Tohoku University, Aoba ku, Sendai, Japan
    Int J Prosthodont 23:299-309. 2010
  2. doi request reprint A novel analytical method to evaluate directly catalase activity of microorganisms and mammalian cells by ESR oximetry
    Keisuke Nakamura
    New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan
    Free Radic Res 44:1036-43. 2010
  3. pmc Photo-irradiation of proanthocyanidin as a new disinfection technique via reactive oxygen species formation
    Keisuke Nakamura
    Laboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, Sendai, Japan
    PLoS ONE 8:e60053. 2013
  4. ncbi request reprint Novel denture-cleaning system based on hydroxyl radical disinfection
    Taro Kanno
    Tohoku University Graduate School of Dentistry, Sendai, Japan
    Int J Prosthodont 25:376-80. 2012
  5. pmc In vitro evaluation of the risk of inducing bacterial resistance to disinfection treatment with photolysis of hydrogen peroxide
    Hiroyo Ikai
    Tohoku University Graduate School of Dentistry, Aoba ku, Sendai, Japan
    PLoS ONE 8:e81316. 2013
  6. doi request reprint In vitro and in vivo anti-Staphylococcus aureus activities of a new disinfection system utilizing photolysis of hydrogen peroxide
    Eisei Hayashi
    Tohoku University Graduate School of Dentistry, Aoba ku, Sendai, Japan
    J Biosci Bioeng 114:193-7. 2012
  7. pmc Synergistic effect of thermal energy on bactericidal action of photolysis of H₂O₂ in relation to acceleration of hydroxyl radical generation
    Midori Shirato
    Division of Fixed Prosthodontics, Department of Restorative Dentistry, Tohoku University Graduate School of Dentistry, Seiryou 4 1, Aoba ku, Sendai 980 8575, Japan
    Antimicrob Agents Chemother 56:295-301. 2012
  8. ncbi request reprint Corrosive effect of disinfection solution containing hydroxyl radicals generated by photolysis of H(2)O(2) on dental metals
    Keisuke Nakamura
    Laboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, 4 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Dent Mater J 31:941-6. 2012
  9. doi request reprint Microbial resistance in relation to catalase activity to oxidative stress induced by photolysis of hydrogen peroxide
    Keisuke Nakamura
    New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan
    Microbiol Immunol 56:48-55. 2012
  10. ncbi request reprint In vitro bactericidal activity of photo-irradiated oxydol products via hydroxyl radical generation
    Akira Oyamada
    Tohoku University Graduate School of Dentistry, 4 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Biocontrol Sci 18:83-8. 2013

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Zirconia as a dental implant abutment material: a systematic review
    Keisuke Nakamura
    New Industry Creation Hatchery Center, Tohoku University, Aoba ku, Sendai, Japan
    Int J Prosthodont 23:299-309. 2010
    ..The focus of this systematic review was to assess the published data concerning zirconia dental implant abutments from various aspects...
  2. doi request reprint A novel analytical method to evaluate directly catalase activity of microorganisms and mammalian cells by ESR oximetry
    Keisuke Nakamura
    New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan
    Free Radic Res 44:1036-43. 2010
    ..The present study indicates that it is possible to evaluate directly the catalase activity of various micro-organisms and mammalian cells by using an ESR oximetry technique...
  3. pmc Photo-irradiation of proanthocyanidin as a new disinfection technique via reactive oxygen species formation
    Keisuke Nakamura
    Laboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, Sendai, Japan
    PLoS ONE 8:e60053. 2013
    ..The present study suggests that photo-irradiated proanthocyanidin whenever used in an optimal concentration range can be a new disinfection technique...
  4. ncbi request reprint Novel denture-cleaning system based on hydroxyl radical disinfection
    Taro Kanno
    Tohoku University Graduate School of Dentistry, Sendai, Japan
    Int J Prosthodont 25:376-80. 2012
    ..The clinical test demonstrated that the device could effectively reduce microorganisms in denture plaque by approximately 7-log order within 20 minutes...
  5. pmc In vitro evaluation of the risk of inducing bacterial resistance to disinfection treatment with photolysis of hydrogen peroxide
    Hiroyo Ikai
    Tohoku University Graduate School of Dentistry, Aoba ku, Sendai, Japan
    PLoS ONE 8:e81316. 2013
    ..In conclusion, disinfection treatment with photolysis of H2O2 appears to be a potential alternative for existing antimicrobial agents in terms of a low risk of inducing bacterial resistance. ..
  6. doi request reprint In vitro and in vivo anti-Staphylococcus aureus activities of a new disinfection system utilizing photolysis of hydrogen peroxide
    Eisei Hayashi
    Tohoku University Graduate School of Dentistry, Aoba ku, Sendai, Japan
    J Biosci Bioeng 114:193-7. 2012
    ..aureus was obtained, it is expected that in vitro antibacterial effect attributable to hydroxyl radicals generated by photolysis of H(2)O(2) could be well reflected in in vivo superficial bacterial infection...
  7. pmc Synergistic effect of thermal energy on bactericidal action of photolysis of H₂O₂ in relation to acceleration of hydroxyl radical generation
    Midori Shirato
    Division of Fixed Prosthodontics, Department of Restorative Dentistry, Tohoku University Graduate School of Dentistry, Seiryou 4 1, Aoba ku, Sendai 980 8575, Japan
    Antimicrob Agents Chemother 56:295-301. 2012
    ..These findings suggest that the thermal energy accelerates the generation of hydroxyl radical by photolysis of H(2)O(2), which in turn results in a synergistic bactericidal effect of hydroxyl radical and thermal energy...
  8. ncbi request reprint Corrosive effect of disinfection solution containing hydroxyl radicals generated by photolysis of H(2)O(2) on dental metals
    Keisuke Nakamura
    Laboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, 4 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Dent Mater J 31:941-6. 2012
    ....
  9. doi request reprint Microbial resistance in relation to catalase activity to oxidative stress induced by photolysis of hydrogen peroxide
    Keisuke Nakamura
    New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan
    Microbiol Immunol 56:48-55. 2012
    ..The results of the present study suggest that the microbicidal effects of hydroxyl radicals generated by photolysis of H(2)O(2) can be alleviated by decomposition of H(2)O(2) by catalase in microorganisms...
  10. ncbi request reprint In vitro bactericidal activity of photo-irradiated oxydol products via hydroxyl radical generation
    Akira Oyamada
    Tohoku University Graduate School of Dentistry, 4 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Biocontrol Sci 18:83-8. 2013
    ..The results strongly suggest that any of the oxydol products tested in the present study can be used as a source of hydroxyl radicals for the disinfection technique developed in our laboratory...
  11. pmc Presence of hydrogen peroxide, a source of hydroxyl radicals, in acid electrolyzed water
    Takayuki Mokudai
    Tohoku University Graduate School of Dentistry, Sendai, Japan
    PLoS ONE 7:e46392. 2012
    ..The hydroxyl radical, an oxygen radical species, is often suggested as a putative active ingredient for AEW antimicrobial activity...
  12. ncbi request reprint Topical treatment of oral cavity and wounded skin with a new disinfection system utilizing photolysis of hydrogen peroxide in rats
    Yasutomo Yamada
    Tohoku University Graduate School of Dentistry, Sendai, Japan
    J Toxicol Sci 37:329-35. 2012
    ....
  13. doi request reprint Bactericidal action of photoirradiated gallic acid via reactive oxygen species formation
    Keisuke Nakamura
    Laboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, 4 1 Seiryo, Aoba ku, Sendai 980 8575, Japan
    J Agric Food Chem 60:10048-54. 2012
    ..Thus, the present study suggests that the photo-oxidation can enhance the antimicrobial activity of gallic acid via hydroxyl radical formation. ..
  14. doi request reprint Fracture resistance of computer-aided design/computer-aided manufacturing-generated composite resin-based molar crowns
    Akio Harada
    Division of Molecular and Regenerative Prosthodontics, Tohoku University Graduate School of Dentistry, Sendai, Japan
    Eur J Oral Sci 123:122-9. 2015
    ..Therefore, CAD/CAM-generated crowns, without internal defects, may be applied to molar regions with sufficient fracture resistance...
  15. doi request reprint Synergistic interaction between wavelength of light and concentration of H₂O₂ in bactericidal activity of photolysis of H₂O₂
    Toshihide Toki
    Tohoku University Graduate School of Dentistry, 4 1 Seiryo, Aoba ku, Sendai 980 8575, Japan
    J Biosci Bioeng 119:358-62. 2015
    ....
  16. pmc Bactericidal action of photogenerated singlet oxygen from photosensitizers used in plaque disclosing agents
    Kirika Ishiyama
    Tohoku University Graduate School of Dentistry, Sendai, Japan
    PLoS ONE 7:e37871. 2012
    ..In PDT, once the photosensitizer is irradiated with light of a specific wavelength, it transfers the excitation energy to molecular oxygen, which gives rise to singlet oxygen...
  17. pmc Cytoprotective effects of grape seed extract on human gingival fibroblasts in relation to its antioxidant potential
    Yusuke Katsuda
    Tohoku University Graduate School of Dentistry, Sendai, Japan
    PLoS ONE 10:e0134704. 2015
    ..These results suggest that the cytoprotective effects of GSE are likely exerted independently of its antioxidant potential. ..
  18. doi request reprint Bactericidal Activity and Mechanism of Photoirradiated Polyphenols against Gram-Positive and -Negative Bacteria
    Keisuke Nakamura
    Laboratory for Redox Regulation, Division of Molecular and Regenerative Prosthodontics, and Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, 4 1 Seiryo, Aoba ku, Sendai 980 8575, Japan
    J Agric Food Chem 63:7707-13. 2015
    ..The present study suggests that blue light irradiation of polyphenols could be a novel disinfection treatment. ..
  19. pmc Cytoprotective effect of short-term pretreatment with proanthocyanidin on human gingival fibroblasts exposed to harsh environmental conditions
    Michiko Kurauchi
    Tohoku University Graduate School of Dentistry, Aoba ku, Sendai, Japan
    PLoS ONE 9:e113403. 2014
    ..Thus, the results suggest that a short-term PA treatment exerts cytoprotective effects on HGFs exposed to harsh environmental conditions by improving the intracellular oxidative stress response. ..
  20. ncbi request reprint Influence of a new denture cleaning technique based on photolysis of H(2)O(2) the mechanical properties and color change of acrylic denture base resin
    Tatsuro Nakahara
    Division of Fixed Prosthodontics, Tohoku University Graduate School of Dentistry, 4 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
    Dent Mater J 32:529-36. 2013
    ..Nonetheless, the degraded flexural strength and altered color of acrylic resin after 500 times of cleaning in the disinfection system would be within clinically acceptable levels. ..
  21. doi request reprint Influence of grain size and veneer firing process on the flexural strength of zirconia ceramics
    Keisuke Nakamura
    Laboratory for Redox Regulation, Tohoku University Graduate School of Dentistry, Sendai, Japan
    Eur J Oral Sci 120:249-54. 2012
    ..The raw materials and the sintering process used should be selected appropriately to avoid grain coarsening because it was found that the strength was influenced by large grains...
  22. doi request reprint Determination of reactive oxygen species generated by phorbol 12-myristate 13-acetate-stimulated oral polymorphonuclear cells from healthy human volunteers without any dental problems
    Noriko Yaekashiwa
    PAX Co, Ltd, 6 6 3 Minamiyoshinari, Sendai, Miyagi 989 3204, Japan
    Arch Oral Biol 57:636-41. 2012
    ..The present study suggests that OPMNs in health individuals have an ability to generate free radicals, which consist mainly of O(2)(·-), (·)OH and possibly an intermediate ROS derived from O(2)(·-) and (·)OH...
  23. pmc Reevaluation of analytical methods for photogenerated singlet oxygen
    Keisuke Nakamura
    New Industry Creation Hatchery Center, Tohoku University, 6 6 10 Aoba, Aramaki, Aoba ku, Sendai 980 8579, Japan
    J Clin Biochem Nutr 49:87-95. 2011
    ..Therefore, in photodynamic therapy, it is suggested that the relative yield of singlet oxygen generated by various photosensitizers can be evaluated properly by electron spin resonance analysis...
  24. pmc Literature review of the role of hydroxyl radicals in chemically-induced mutagenicity and carcinogenicity for the risk assessment of a disinfection system utilizing photolysis of hydrogen peroxide
    Taro Kanno
    Tohoku University Graduate School of Dentistry, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    J Clin Biochem Nutr 51:9-14. 2012
    ..From these, we conclude that there would seem to be little to no risk in using the hydroxyl radical as a disinfectant for short-term treatment of the oral cavity...
  25. pmc Photolysis of hydrogen peroxide, an effective disinfection system via hydroxyl radical formation
    Hiroyo Ikai
    New Industry Creation Hatchery Center, Tohoku University, Aoba 6 6 10, Aramaki, Aoba ku, Sendai 980 8579, Japan
    Antimicrob Agents Chemother 54:5086-91. 2010
    ..Other results demonstrated that the bactericidal activity was dependent on the amount of hydroxyl radicals generated. Treatment of bacteria with 200 to 300 μM hydroxyl radicals would result in reductions of viable counts of >99.99%...
  26. ncbi request reprint [What prosthodontic therapy should we select for periodontally compromised patients? Part 2: Review of the literature focusing on conventional prosthodontic therapy for periodontally compromised patients and clinical implication (RPD vs FPD vs implant)]
    Taro Kanno
    Division of the Fixed Prosthodontics, Department of Restorative Dentistry, Tohoku University Graduate School of Dentistry
    Nihon Hotetsu Shika Gakkai Zasshi 52:143-9. 2008
    ..In addition, prosthodontic management in periodontitis-susceptible subjects was evaluated from the results of Part 1 and Part 2...
  27. ncbi request reprint [What prosthodontic therapy should we select for periodontally compromised patients? Part 1: Review of the literature focusing on implant therapy for periodontally compromised patients]
    Taro Kanno
    Division of Fixed Prosthodontics, Department of Restorative Dentistry, Tohoku University Graduate School of Dentistry
    Nihon Hotetsu Shika Gakkai Zasshi 52:135-42. 2008
    ..The aim of the present study was is to consider scientific evidence on implant treatment for periodontitis-susceptible subjects with partially edentulous dentate...
  28. pmc Bactericidal Effect of Photolysis of H2O2 in Combination with Sonolysis of Water via Hydroxyl Radical Generation
    Hong Sheng
    Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Miyagi, Japan
    PLoS ONE 10:e0132445. 2015
    ....
  29. doi request reprint Acceleration of proliferative response of mouse fibroblasts by short-time pretreatment with polyphenols
    Makoto Tsuruya
    Tohoku University Graduate School of Dentistry, 4 1 Seiryo machi, Aoba ku, Sendai, 980 8575, Japan
    Appl Biochem Biotechnol 174:2223-35. 2014
    ....