Affiliation: Shiseido Research Center
- Stress and the skinJ Hosoi
Life Science Research Center, Shiseido, Kanazawa, Yokohama, Japan
Int J Cosmet Sci 28:243-6. 2006..Skin is also a target organ of the stress reaction. What the effects of stress are and how stress affects the skin are summarized in this review. Possible use of fragrance for the regulation of the stress reaction is also introduced...
- Regulation of cutaneous allergic reaction by odorant inhalationJ Hosoi
Life Science Research Center, Shiseido, Yokohama, Japan
J Invest Dermatol 114:541-4. 2000..Serum interleukin-12 was downregulated by exposure to citralva or lyral/lilial. These data demonstrate that olfactory stimuli regulate the cutaneous immune system...
- Mitigation of stress-induced suppression of contact hypersensitivity by odorant inhalationJ Hosoi
Shiseido Life Science Research Center, 2 12 1 Fukuura, Kanazawa, Yokohama 236 8643, Japan
Br J Dermatol 145:716-9. 2001..Various skin functions are affected by stress. We have previously shown that odorant inhalation can regulate skin immune reactions...
- Regulation of plasma substance P and skin mast cells by odorantsJunichi Hosoi
Shiseido Life Science Research Center, Yokohama 236 8643, Japan
J Cutan Med Surg 7:287-91. 2003..Stress exacerbates some skin diseases. We have reported that inhalation of certain odorants modulates immune reactions in the skin...
- Stress augmented ultraviolet-irradiation-induced pigmentationKaori Inoue
Shiseido Research Center, Yokohama, Japan
J Invest Dermatol 121:165-71. 2003..These results suggest that adrenocorticotropic hormone is at least partly responsible for the sensitivity of the pigmentary response after ultraviolet irradiation under stressful conditions...
- Extracellular ATP has stimulatory effects on the expression and release of IL-6 via purinergic receptors in normal human epidermal keratinocytesKaori Inoue
Shiseido Research Center, Kanazawa Ku, Yokohama, Japan
J Invest Dermatol 127:362-71. 2007..Furthermore, in UVB-radiated cells, we note the possibility that P2 receptor antagonists may reduce skin inflammation...
- Glucocorticoids enhance Toll-like receptor 2 expression in human keratinocytes stimulated with Propionibacterium acnes or proinflammatory cytokinesMichio Shibata
Shiseido Research Center, Yokohama, Japan
J Invest Dermatol 129:375-82. 2009..acnes existing as normal resident flora plays an important role in the exacerbation of acne vulgaris as well as in possible induction of corticosteroid-induced acne or in that of rosacea-like dermatitis...
- Neuropeptides concentrations in the skin of a murine (NC/Nga mice) model of atopic dermatitisMasako Katsuno
Department of Environmental Immuno Dermatology, Yokohama City University Graduate School of Medicine, 3 9 Fukuura, Kanazawa, Yokohama, Japan
J Dermatol Sci 33:55-65. 2003..It has been reported that the expression of neuropeptides (NPs), and the density and structure of peripheral nerves in atopic dermatitis (AD) are different from those in normal skin...
- Functional characteristics of the skin surface of children approaching puberty: age and seasonal influencesNobuko Akutsu
Shiseido Life Science Research Center, Yokohama, Japan
Acta Derm Venereol 89:21-7. 2009..We conclude that, until puberty, most functional characteristics of the skin of children remain distinct from those of adults...
- Neuropeptide control mechanisms in cutaneous biology: physiological and clinical significanceEva M J Peters
Department of Internal Medicine, Psychosomatics, Biomedical Research Center, Universitätsmedizin Charité, Campus Virchow Klinikum, Berlin, Germany
J Invest Dermatol 126:1937-47. 2006..Progress in this field will likely result in novel therapies for the management of diseases characterized by deregulated inflammation, tissue remodeling, angiogenesis, and neoplasm...
- Catecholamines inhibit the antigen-presenting capability of epidermal Langerhans cellsKristina Seiffert
Department of Dermatology and Neurology, Joan and Sanford I Weill Medical College of Cornell University, New York, NY 10021, USA
J Immunol 168:6128-35. 2002..Thus, catecholamines may have both local and systemic effects. We conclude that specific ARs are expressed on LC and that signaling through these receptors can decrease epidermal immune reactions...