Keisuke Mori

Summary

Affiliation: Saitama Medical School
Country: Japan

Publications

  1. ncbi request reprint Photodynamic therapy of experimental choroidal neovascularization with a hydrophilic photosensitizer: mono-L-aspartyl chlorin e6
    K Mori
    Department of Ophthalmology, Saitama Medical School, Japan
    Retina 21:499-508. 2001
  2. doi request reprint Posterior vitreous mobility delineated by tracking of optical coherence tomography images in eyes with idiopathic macular holes
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan Electronic address
    Am J Ophthalmol 159:1132-1141.e1. 2015
  3. pmc Five-year results of photodynamic therapy with verteporfin for Japanese patients with neovascular age-related macular degeneration
    Takashi Tsuchihashi
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Clin Ophthalmol 7:615-20. 2013
  4. doi request reprint Montage images of spectral-domain optical coherence tomography in eyes with idiopathic macular holes
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Ophthalmology 119:2600-8. 2012
  5. ncbi request reprint Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Faculty of Medicine, 38 Morohongo, Moroyama, Iruma, Saitama, 350 0495, Japan
    J Hum Genet 52:636-41. 2007
  6. ncbi request reprint Comparison of epiretinal membranes of differing pathogenesis using optical coherence tomography
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, 38 Morohongo, Moroyama, Iruma, Saitama 350 0495, Japan
    Retina 24:57-62. 2004
  7. ncbi request reprint Treatment of stage 2 macular hole by intravitreous injection of expansile gas and induction of posterior vitreous detachment
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University Faculty of Medicine, Iruma, Japan
    Ophthalmology 114:127-33. 2007
  8. ncbi request reprint Coding and noncoding variants in the CFH gene and cigarette smoking influence the risk of age-related macular degeneration in a Japanese population
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, Moroyama, Iruma, Saitama, Japan
    Invest Ophthalmol Vis Sci 48:5315-9. 2007
  9. ncbi request reprint The ultra-late phase of indocyanine green angiography for healthy subjects and patients with age-related macular degeneration
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, Saitama, Japan
    Retina 22:309-16. 2002
  10. ncbi request reprint Asymmetry of choroidal venous vascular patterns in the human eye
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, 38 Morohongo, Moroyama, Iruma, Saitama 350 0495, Japan
    Ophthalmology 111:507-12. 2004

Collaborators

Detail Information

Publications49

  1. ncbi request reprint Photodynamic therapy of experimental choroidal neovascularization with a hydrophilic photosensitizer: mono-L-aspartyl chlorin e6
    K Mori
    Department of Ophthalmology, Saitama Medical School, Japan
    Retina 21:499-508. 2001
    ..To demonstrate the selective localization of the hydrophilic photosensitizer mono-L-aspartyl chlorin e6 (NPe6) in experimental choroidal neovascularization in nonhuman primate eyes...
  2. doi request reprint Posterior vitreous mobility delineated by tracking of optical coherence tomography images in eyes with idiopathic macular holes
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan Electronic address
    Am J Ophthalmol 159:1132-1141.e1. 2015
    ..To demonstrate the posterior vitreous mobility following eye movements in patients forming macular holes, using an optical coherence tomography (OCT) eye-tracking system...
  3. pmc Five-year results of photodynamic therapy with verteporfin for Japanese patients with neovascular age-related macular degeneration
    Takashi Tsuchihashi
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Clin Ophthalmol 7:615-20. 2013
    ..To describe the treatment outcome of photodynamic therapy (PDT) in Japanese patients with age-related macular degeneration (AMD) followed for 5 years...
  4. doi request reprint Montage images of spectral-domain optical coherence tomography in eyes with idiopathic macular holes
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Ophthalmology 119:2600-8. 2012
    ..Montaged images of posterior and peripheral spectral-domain (SD) optical coherence tomography (OCT) studies were used to describe the anatomic vitreoretinal relationships...
  5. ncbi request reprint Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Faculty of Medicine, 38 Morohongo, Moroyama, Iruma, Saitama, 350 0495, Japan
    J Hum Genet 52:636-41. 2007
    ....
  6. ncbi request reprint Comparison of epiretinal membranes of differing pathogenesis using optical coherence tomography
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, 38 Morohongo, Moroyama, Iruma, Saitama 350 0495, Japan
    Retina 24:57-62. 2004
    ..To compare optical coherence tomography (OCT) images of idiopathic epiretinal membranes (ERMs) with those of secondary ERMs...
  7. ncbi request reprint Treatment of stage 2 macular hole by intravitreous injection of expansile gas and induction of posterior vitreous detachment
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University Faculty of Medicine, Iruma, Japan
    Ophthalmology 114:127-33. 2007
    ..To demonstrate the morphological and functional outcomes of intravitreous injection of an expansile gas bubble for the treatment of stage 2 macular holes...
  8. ncbi request reprint Coding and noncoding variants in the CFH gene and cigarette smoking influence the risk of age-related macular degeneration in a Japanese population
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, Moroyama, Iruma, Saitama, Japan
    Invest Ophthalmol Vis Sci 48:5315-9. 2007
    ..The present study was undertaken to investigate whether four coding and noncoding variants of the CFH gene, including rs1410996, are associated with AMD in native, unrelated Japanese patients...
  9. ncbi request reprint The ultra-late phase of indocyanine green angiography for healthy subjects and patients with age-related macular degeneration
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, Saitama, Japan
    Retina 22:309-16. 2002
    ..To compare the characteristics of residual fundus fluorescence observed in the ultra-late phase of indocyanine green (ICG) angiography, in normal subjects and in patients with age-related macular degeneration (ARMD)...
  10. ncbi request reprint Asymmetry of choroidal venous vascular patterns in the human eye
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, 38 Morohongo, Moroyama, Iruma, Saitama 350 0495, Japan
    Ophthalmology 111:507-12. 2004
    ..To describe the angioarchitecture of choroidal veins in normal subjects using indocyanine green (ICG) angiography...
  11. doi request reprint Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Ophthalmology 117:928-38. 2010
    ..To describe phenotype and genotype characteristics of age-related macular degeneration (AMD) in Japanese patients...
  12. ncbi request reprint Decreased arterial dye-filling and venous dilation in the macular choroid associated with age-related macular degeneration
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, Iruma, Saitama, Japan
    Retina 25:430-7. 2005
    ..To compare the angioarchitecture of choroidal arteries and veins in patients with age-related macular degeneration (AMD) to the angioarchitecture of age-matched normal subjects using indocyanine green (ICG) angiography...
  13. doi request reprint Complement factor H and high-temperature requirement A-1 genotypes and treatment response of age-related macular degeneration
    Takashi Tsuchihashi
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Ophthalmology 118:93-100. 2011
    ....
  14. ncbi request reprint Promoter polymorphisms of the pigment epithelium-derived factor gene are associated with diabetic retinopathy
    Hiroyuki Iizuka
    Division of RI Laboratory, Biomedical Research Center, Saitama Medical University, Saitama, Japan
    Biochem Biophys Res Commun 361:421-6. 2007
    ..These results demonstrate that the PEDF gene, in cooperation with the VEGF gene, may contribute to the development of DR...
  15. ncbi request reprint Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes
    Takuya Awata
    Division of Endocrinology and Diabetes, Department of Medicine, Saitama Medical School, Saitama, Japan
    Biochem Biophys Res Commun 333:679-85. 2005
    ..These results demonstrate that the VEGF C-634G polymorphism is a genetic risk factor for ME as well as DR...
  16. ncbi request reprint Intraocular gene transfer of pigment epithelium-derived factor rescues photoreceptors from light-induced cell death
    Daisuke Imai
    Department of Ophthalmology, Saitama Medical School, Iruma, Saitama, Japan
    J Cell Physiol 202:570-8. 2005
    ....
  17. doi request reprint Photodynamic effects on retinal oxygen saturation, blood flow, and electrophysiological function in patients with neovascular age-related macular degeneration
    Takashi Tsuchihashi
    Department of Ophthalmology, Saitama Medical University School of Medicine, Iruma, Saitama, Japan
    Retina 29:1450-6. 2009
    ....
  18. ncbi request reprint Laser photocoagulation and, to a lesser extent, photodynamic therapy target and enhance adenovirus vector-mediated gene transfer in the rat retina
    Kaname Anzai
    Department of Ophthalmology, Saitama Medical School, Japan
    Invest Ophthalmol Vis Sci 46:3883-91. 2005
    ..To evaluate the transduction efficiency and localization of a reporter gene after intravitreous injection of adenovirus vector in laser photocoagulation (PC)- and photodynamic therapy (PDT)-treated eyes...
  19. ncbi request reprint Transpupillary thermotherapy-induced modification of angiogenesis- and coagulation-related gene expression in the rat posterior fundus
    Yoko N Ito
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Mol Vis 12:802-10. 2006
    ....
  20. doi request reprint Retinal adaptability loss in serous retinal detachment with central serous chorioretinopathy
    Yoshiaki Shimada
    Department of Ophthalmology, Fujita Health University Banbuntane Hotokukai Hospital, Aichi, Japan
    Invest Ophthalmol Vis Sci 51:3210-5. 2010
    ..To investigate the functional characteristics of the detached retina on a serous retinal detachment (SRD) in eyes with central serous chorioretinopathy (CSC) with spared visual acuity...
  21. ncbi request reprint [Current and future trends in gene therapy for diabetic retinopathies]
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School
    Nihon Rinsho 63:250-5. 2005
  22. ncbi request reprint Intraocular biodistribution of mono-L-aspartyl chlorin e6 in a primate choroidal neovascularization model
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Ophthalmic Surg Lasers Imaging 38:142-7. 2007
    ..To describe the biodistribution of a hydrophilic sensitizer, mono-L-aspartyl chlorin e6 (NPe6), in a primate model of choroidal neovascularization (CNV)...
  23. doi request reprint Associations of cigarette smoking but not serum fatty acids with age-related macular degeneration in a Japanese population
    Sho Kabasawa
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan
    Ophthalmology 118:1082-8. 2011
    ..To assess modifiable environmental risk factors and protective factors for age-related macular degeneration (AMD) in a native Japanese population...
  24. ncbi request reprint Transpupillary thermotherapy: effect of wavelength on normal primate retina
    Yoko Ito
    Department of Ophthalmology, Saitama Medical School, Saitama, Japan
    Retina 25:1046-53. 2005
    ..To correlate changes in primate fundus after transpupillary thermotherapy (TTT) at two wavelengths...
  25. pmc A genome-wide association study for diabetic retinopathy in a Japanese population: potential association with a long intergenic non-coding RNA
    Takuya Awata
    Department of Endocrinology and Diabetes, Faculty of Medicine, Saitama Medical University, Saitama, Japan
    PLoS ONE 9:e111715. 2014
    ..The present study raises the possibility that the dysregulation of ciliary-associated genes plays a role in susceptibility to DR...
  26. doi request reprint Association of elastin gene polymorphism to age-related macular degeneration and polypoidal choroidal vasculopathy
    Kenji Yamashiro
    Department of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    Invest Ophthalmol Vis Sci 52:8780-4. 2011
    ..To see if there is an association in Japanese between elastin gene (ELN) polymorphisms and neovascular age-related macular degeneration (AMD) or its subtypes, typical AMD (tAMD) and polypoidal choroidal vasculopathy (PCV)...
  27. ncbi request reprint Retinal neuroprotection against ischemic injury mediated by intraocular gene transfer of pigment epithelium-derived factor
    Hiroyasu Takita
    Department of Ophthalmology, Saitama Medical School, Saitama, Japan
    Invest Ophthalmol Vis Sci 44:4497-504. 2003
    ..To determine whether intraocular gene transfer of pigment epithelium-derived factor (PEDF) protects the retina from ischemia-reperfusion injury...
  28. ncbi request reprint [Corneal subepithelial infiltrates that developed following intravitreous injection of bevacizumab]
    Fumi Yamato
    Department of Ophthalmology, Saitama Medical University, 38 Morohongo, Moroyama, Iruma gun, Saitama ken 350 0495, Japan
    Nippon Ganka Gakkai Zasshi 117:558-60. 2013
    ..Reports of adverse reactions derived from bevacizumab itself are rare. We report a case in which corneal subepithelial infiltrates developed following IVB...
  29. ncbi request reprint [Quantitative analysis of indocyanine green angiography in multifocal posterior pigment epitheliopathy and its related diseases]
    Akemi Sano
    Department of Ophthalmology, Saitama Medical School, 38 Morohongo, Moroyama machi, Iruma gun, Saitama 350 0495, Japan
    Nihon Ganka Gakkai Zasshi 106:221-8. 2002
    ..To clarify the indocyanine green(ICG) angiographic features in multifocal posterior pigment epitheliopathy(MPPE), we measured the maximum diameter of the choroidal vein and mean fluorescence intensity within the vascular arcade...
  30. ncbi request reprint Endothelial nitric oxide synthase gene is associated with diabetic macular edema in type 2 diabetes
    Takuya Awata
    The Fourth Department of Medicine, Saitama Medical School, 38 Morohongo, Moroyama, Iruma gun, Saitama, 350 0495, Japan
    Diabetes Care 27:2184-90. 2004
    ..We examined the endothelial nitric oxide (eNOS) gene polymorphisms to assess its possible association with diabetic retinopathy and macular edema...
  31. ncbi request reprint [Outcome of photodynamic therapy for exudative age-related macular degeneration with good visual acuity]
    Takashi Tsuchihashi
    Department of Ophthalmology, Saitama Medical School, Saitama Ken, Japan
    Nippon Ganka Gakkai Zasshi 114:7-13. 2010
    ..To evaluate visual outcome one year after photodynamic therapy (PDT) in patients with exudative age-related macular degeneration (AMD) showing good visual acuity (VA)...
  32. pmc Ocular localization and transduction by adenoviral vectors are serotype-dependent and can be modified by inclusion of RGD fiber modifications
    Kazuhiro Ueyama
    Department of Ophthalmology, Saitama Medical University, Moroyama, Iruma, Saitama, Japan
    PLoS ONE 9:e108071. 2014
    ..To evaluate localization and transgene expression from adenoviral vector of serotypes 5, 35, and 28, ± an RGD motif in the fiber following intravitreal or subretinal administration...
  33. ncbi request reprint Enhanced documentation of slit-lamp images of the human vitreous stained with fluorescein sodium
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical School, Iruma, Saitama, Japan
    Ophthalmic Surg Lasers Imaging 35:233-8. 2004
    ..To develop a new method to document the slit-lamp image of the vitreous body as stained with fluorescein sodium...
  34. ncbi request reprint [Ultra-late phase of indocyanine green angiography in a case with metastatic choroidal tumor]
    Yuriko Tochitani
    Department of Ophthalmology, Saitama Medical School, 38 Morohongo, Moroyama, Iruma gun, Saitama 350 0495, Japan
    Nihon Ganka Gakkai Zasshi 110:205-10. 2006
    ..To report a case with metastatic choroidal tumor evaluated with ultra-late phase of indocyanine green (ICG) angiography...
  35. pmc RETINOCHOROIDAL MORPHOLOGY DESCRIBED BY WIDE-FIELD MONTAGE IMAGING OF SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY
    Keisuke Mori
    Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan Department of Ophthalmology, International University of Health and Welfare, Nasu Shiobara, Tochigi, Japan and The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland
    Retina 36:375-84. 2016
    ..To present baseline images of the vitreous, retina, and choroid from the macula to the periphery in normal patients using a novel montaging technique of spectral domain optical coherence tomography...
  36. ncbi request reprint Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor
    Keisuke Mori
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 9277, USA
    Invest Ophthalmol Vis Sci 43:2428-34. 2002
    ....
  37. ncbi request reprint Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth
    Elia J Duh
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Maumenee 809, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Invest Ophthalmol Vis Sci 43:821-9. 2002
    ....
  38. ncbi request reprint Optical coherence tomography of enucleated human eye specimens with histological correlation: origin of the outer "red line"
    Nicola G Ghazi
    University of Virginia Health System, Charlottesville, Virginia, USA
    Am J Ophthalmol 141:719-26. 2006
    ..To further define the origin of the "outer red line" (ORL) present in retinal optical coherence tomograms...
  39. ncbi request reprint Retina-specific expression of PDGF-B versus PDGF-A: vascular versus nonvascular proliferative retinopathy
    Keisuke Mori
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 9277, USA
    Invest Ophthalmol Vis Sci 43:2001-6. 2002
    ..This study was undertaken to determine whether higher levels of endogenously produced PDGF-A in the retinas of mice result in retinal detachment...
  40. ncbi request reprint Clinicopathological correlation of a retinal angiomatous proliferation-like lesion in a case of radiation retinopathy
    Kaname Anzai
    Jpn J Ophthalmol 50:291-3. 2006
  41. ncbi request reprint Nitric oxide is proangiogenic in the retina and choroid
    Akira Ando
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Maumenee, N Wolfe Street, Baltimore, Maryland 21287 9277, USA
    J Cell Physiol 191:116-24. 2002
    ..A broad spectrum NOS inhibitor may have therapeutic potential for treatment of both retinal and choroidal neovascularization...
  42. ncbi request reprint Diagnostic and theraputic challenges
    Izume Kawasaki
    Retina 27:253-8. 2007
  43. ncbi request reprint Optical coherence tomography of peripheral retinal lesions in enucleated human eye specimens with histologic correlation
    Nicola G Ghazi
    University of Virginia Health System, Charlottesville, Virginia, USA
    Am J Ophthalmol 141:740-2. 2006
    ..To report optical coherence tomography (OCT) histologic correlations of three common peripheral retinal lesions and to explore the feasibility of the use of OCT to image retinal pathologic conditions in fixed tissue specimens...
  44. ncbi request reprint Topical nepafenac inhibits ocular neovascularization
    Kyoichi Takahashi
    Departments of Ophthalmology and Neuroscience, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287 9277, USA
    Invest Ophthalmol Vis Sci 44:409-15. 2003
    ..In this study, we tested the effect of topical nepafenac in three murine models of ocular neovascularization (NV)...
  45. doi request reprint Periocular triamcinolone enhances intraocular gene expression after delivery by adenovirus
    Choul Yong Park
    Department of Ophthalmology, Johns Hopkins University School of Medicine, 1550 Orleans Street, Baltimore, MD 21287, USA
    Invest Ophthalmol Vis Sci 49:399-406. 2008
    ..The optical signal was then used as a bioassay to determine whether periocular immune modulation affects intraocular transgene expression...
  46. ncbi request reprint Intraocular adenoviral vector-mediated gene transfer in proliferative retinopathies
    Keisuke Mori
    Departments of Ophthalmology and Neuroscience, The Johns Hopkins University School of Medicine, Maumenee 719, 600 N Wolfe Street, Baltimore, MD 21287 9277, USA
    Invest Ophthalmol Vis Sci 43:1610-5. 2002
    ....
  47. ncbi request reprint AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization
    Keisuke Mori
    Departments of Ophthalmology and Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 9277, USA
    Invest Ophthalmol Vis Sci 43:1994-2000. 2002
    ..The purpose of this study was to determine whether AAV-mediated intraocular gene transfer of pigment epithelium-derived factor (PEDF) inhibits the development of choroidal neovascularization (CNV) in a murine model...
  48. ncbi request reprint Quantitative assessment of the integrity of the blood-retinal barrier in mice
    Nancy L Derevjanik
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 9277, USA
    Invest Ophthalmol Vis Sci 43:2462-7. 2002
    ..The purpose of this study was to develop and characterize a quantitative assay of blood-retinal barrier (BRB) function in mice and to determine the effect of several purported vasopermeability factors on the BRB...