Tatsuhiko Sudo

Summary

Affiliation: RIKEN Brain Science Institute
Country: Japan

Publications

  1. doi request reprint Improvement of photoaffinity SPR imaging platform and determination of the binding site of p62/SQSTM1 to p38 MAP kinase
    Akiko Saito
    Antibiotics Laboratory, Chemical Biology Department, Advanced Research Institute, RIKEN, 2 1 Hirosawa, Wako, Saitama, 351 0198, Japan
    Chem Asian J 3:1607-12. 2008
  2. ncbi request reprint p38 mitogen-activated protein kinase plays a key role in regulating MAPKAPK2 expression
    Tatsuhiko Sudo
    Antibiotics Laboratory and Bioarchitect Research Group, DRI, RIKEN, Wako, Saitama, Japan
    Biochem Biophys Res Commun 337:415-21. 2005
  3. doi request reprint Specific regulation of cytokine-dependent p38 MAP kinase activation by p62/SQSTM1
    Kayoko Kawai
    Antibiotics Laboratory and Bioarchitect Research Group, DRI, RIKEN, 2 1 Hirosawa, Wako, Saitama, 351 0198, Japan
    J Biochem 143:765-72. 2008
  4. doi request reprint A p38 mitogen-activated protein kinase inhibitor screening method using growth recovery of Escherichia coli as an index
    Kayoko Kawai
    Antibiotics Laboratory and Bioarchitect Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351 0198, Japan
    Anal Biochem 388:128-33. 2009
  5. ncbi request reprint Oxidative stress-induced ubiquitination of RCAN1 mediated by SCFbeta-TrCP ubiquitin ligase
    Sachie Asada
    Kishi Initiative Research Unit, Frontier Research System, 2 1 Hirosawa, Wako, Saitama, Japan
    Int J Mol Med 22:95-104. 2008
  6. ncbi request reprint Exip, a splicing variant of p38alpha, participates in interleukin-1 receptor proximal complex and downregulates NF-kappaB pathway
    Yuki Yagasaki
    Antibiotics Laboratory and Bioarchitect Research Group, DRI, RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    FEBS Lett 575:136-40. 2004
  7. ncbi request reprint Involvement of apoptosis signal-regulating kinase-1 on angiotensin II-induced monocyte chemoattractant protein-1 expression
    Takashi Omura
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Arterioscler Thromb Vasc Biol 24:270-5. 2004
  8. ncbi request reprint Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1
    Sachie Asada
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, 1 1 1 Tennoudai, Tsukuba, Ibaraki 305 8577, Japan
    Cell Signal 19:519-27. 2007
  9. ncbi request reprint Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway
    Yoko Irukayama-Tomobe
    Cardiovascular Division, Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Circulation 109:904-10. 2004
  10. ncbi request reprint Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion
    Kinya Otsu
    Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 302:56-60. 2003

Collaborators

  • Hiroyuki Osada
  • Michael Karin
  • Takashi Omura
  • Yasuhiro Nakamura
  • Atsushi Utani
  • Yoshitoshi Kasuya
  • Kayoko Kawai
  • Sachie Asada
  • Akiko Saito
  • Sadao Kimura
  • Yoko Irukayama-Tomobe
  • Tsutomu Kishi
  • Akiyoshi Fukamizu
  • Hiroshi Hama
  • Kana Namiki
  • Yuji Matsuo
  • Kanako Sakurai
  • Yuki Yagasaki
  • Kinya Otsu
  • Katsutoshi Goto
  • Masumi Maruyama
  • Yoko Takanami-Ohnishi
  • Hiroshi Takayama
  • Rina Nagao
  • Akemi Ikeda
  • Hidehito Mukai
  • Satomi Mizuhashi
  • Tomoyuki Kuwaki
  • Hiroaki Daitoku
  • Koichiro Kako
  • Mitsuko Furuya
  • Naoki Tokuhara
  • Shingo Yano
  • Akira Nakamura
  • Shintaro Iwashita
  • Tomoko Saito
  • Hitomi Matsuzaki
  • Motoyuki Iemitsu
  • Takashi Miyauchi
  • Yoh Takuwa
  • Iwao Yamaguchi
  • Takehiro Ogata
  • Satoshi Sakai
  • Masakatsu Takanashi
  • Yasushi Matsumura
  • Yoshiharu Higuchi
  • Shinichi Hirotani
  • Masatsugu Hori
  • Osamu Yamaguchi
  • Kazuhiko Nishida
  • Nobushige Yamashita
  • Shungo Hikoso
  • Tetsuya Watanabe
  • Hajime Tsunoda
  • Shinya Amano

Detail Information

Publications13

  1. doi request reprint Improvement of photoaffinity SPR imaging platform and determination of the binding site of p62/SQSTM1 to p38 MAP kinase
    Akiko Saito
    Antibiotics Laboratory, Chemical Biology Department, Advanced Research Institute, RIKEN, 2 1 Hirosawa, Wako, Saitama, 351 0198, Japan
    Chem Asian J 3:1607-12. 2008
    ..These SPR analysis data and empirical biologic data reveal that the binding site of p62 to p38 is the domain corresponding to 173-182...
  2. ncbi request reprint p38 mitogen-activated protein kinase plays a key role in regulating MAPKAPK2 expression
    Tatsuhiko Sudo
    Antibiotics Laboratory and Bioarchitect Research Group, DRI, RIKEN, Wako, Saitama, Japan
    Biochem Biophys Res Commun 337:415-21. 2005
    ..Together, we have established cell lines that can be used in analyzing the functions of MAPKs, especially p38alpha, and show that p38 is indispensable for MAPKAPK2 expression...
  3. doi request reprint Specific regulation of cytokine-dependent p38 MAP kinase activation by p62/SQSTM1
    Kayoko Kawai
    Antibiotics Laboratory and Bioarchitect Research Group, DRI, RIKEN, 2 1 Hirosawa, Wako, Saitama, 351 0198, Japan
    J Biochem 143:765-72. 2008
    ..Cytokine mRNA is often stabilized via p38 pathway. In the absence of p62, IL-8 mRNA induced by IL-1beta became more fragile. These data show that p62 specifically regulates cytokine-dependent p38 signalling pathway...
  4. doi request reprint A p38 mitogen-activated protein kinase inhibitor screening method using growth recovery of Escherichia coli as an index
    Kayoko Kawai
    Antibiotics Laboratory and Bioarchitect Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351 0198, Japan
    Anal Biochem 388:128-33. 2009
    ..This study demonstrates that this is a promising and economical inhibitor screening method not only for p38 but also for other proteins...
  5. ncbi request reprint Oxidative stress-induced ubiquitination of RCAN1 mediated by SCFbeta-TrCP ubiquitin ligase
    Sachie Asada
    Kishi Initiative Research Unit, Frontier Research System, 2 1 Hirosawa, Wako, Saitama, Japan
    Int J Mol Med 22:95-104. 2008
    ..These results suggest that H2O2 induces SCF beta-TrCP-mediated ubiquitination of RCAN1, leading to a decrease in the protein level of RCAN1...
  6. ncbi request reprint Exip, a splicing variant of p38alpha, participates in interleukin-1 receptor proximal complex and downregulates NF-kappaB pathway
    Yuki Yagasaki
    Antibiotics Laboratory and Bioarchitect Research Group, DRI, RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    FEBS Lett 575:136-40. 2004
    ..Together, these results demonstrate that Exip can be a new component of NF-kappaB pathway, and contribute to a comprehensive understanding of the signal transduction pathway in the inflammatory responses...
  7. ncbi request reprint Involvement of apoptosis signal-regulating kinase-1 on angiotensin II-induced monocyte chemoattractant protein-1 expression
    Takashi Omura
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Arterioscler Thromb Vasc Biol 24:270-5. 2004
    ..To elucidate these molecular mechanisms, angiotensin II-induced expression of MCP-1 was examined in cultured rat neonatal ventricular cardiomyocytes and fibroblasts by adenovirus gene transfer...
  8. ncbi request reprint Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1
    Sachie Asada
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, 1 1 1 Tennoudai, Tsukuba, Ibaraki 305 8577, Japan
    Cell Signal 19:519-27. 2007
    ..These results suggest that Foxo1 is specifically phosphorylated by Erk and p38, and that this phosphorylation regulates the function of Foxo1 as a coactivator for Ets-1...
  9. ncbi request reprint Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway
    Yoko Irukayama-Tomobe
    Cardiovascular Division, Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Circulation 109:904-10. 2004
    ..However, the roles of PPAR-alpha activators in endothelin (ET)-1-induced cardiac hypertrophy are not yet known...
  10. ncbi request reprint Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion
    Kinya Otsu
    Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 302:56-60. 2003
    ..2+/-0.7% in the p38alpha(+/-) heart. These suggested that p38alpha plays a pivotal role in the signal transduction pathway mediating myocardial cell death caused by ischemia-reperfusion...
  11. ncbi request reprint Involvement of p38alpha in kainate-induced seizure and neuronal cell damage
    Kana Namiki
    Department of Biochemistry and Molecular Pharmacology, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    J Recept Signal Transduct Res 27:99-111. 2007
    ..These results suggest that p38alpha signaling pathway plays an important role in epileptic seizure and excitotoxicity...
  12. ncbi request reprint Role of p38 mitogen-activated protein kinase in thrombus formation
    Kanako Sakurai
    Department of Biochemistry and Molecular Pharmacology and Chiba University Graduate School of Medicine, Chiba, Japan
    J Recept Signal Transduct Res 24:283-96. 2004
    ..These results suggest that p38 plays an important role in thrombus formation by regulating platelet function and tissue factor activity...
  13. ncbi request reprint Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity
    Yoko Takanami-Ohnishi
    Department of Biochemistry and Molecular Pharmacology, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba, Japan
    J Biol Chem 277:37896-903. 2002
    ..These results suggest that p38 plays a key role in CHS and is an important target for the treatment of CHS...