Masao Shiozaki

Summary

Affiliation: RIKEN Brain Science Institute
Country: Japan

Publications

  1. doi request reprint Synthesis of RCAI-172 (C6 epimer of RCAI-147) and its biological activity
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan Electronic address
    Bioorg Med Chem 22:827-33. 2014
  2. doi request reprint Synthesis and biological activity of hydroxylated analogues of KRN7000 (α-galactosylceramide)
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Wako Shi, Saitama, Japan
    Carbohydr Res 370:46-66. 2013
  3. doi request reprint Synthesis and biological activity of ester and ether analogues of alpha-galactosylceramide (KRN7000)
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan
    Carbohydr Res 345:1663-84. 2010

Detail Information

Publications3

  1. doi request reprint Synthesis of RCAI-172 (C6 epimer of RCAI-147) and its biological activity
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan Electronic address
    Bioorg Med Chem 22:827-33. 2014
    ..There exist seven chiral centers in the aglycon part of RCAI-172, and even though the change of configuration is just one position (C6-OH), the effect on both Th1/Th2 response and EAE test is fairly large. ..
  2. doi request reprint Synthesis and biological activity of hydroxylated analogues of KRN7000 (α-galactosylceramide)
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Wako Shi, Saitama, Japan
    Carbohydr Res 370:46-66. 2013
    ..It was recognized that two compounds (†)RCAI-147/-160 showed good suppression of EAE symptoms...
  3. doi request reprint Synthesis and biological activity of ester and ether analogues of alpha-galactosylceramide (KRN7000)
    Masao Shiozaki
    Laboratory for Immune Regulation, Research Center for Allergy and Immunology, RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan
    Carbohydr Res 345:1663-84. 2010
    ..Ester analogues 30a, 31a, and 61 showed activity for IFNgamma and IL-4 production of iNKT cells, while ether (31b) and 4-methoxy ester (76) analogues of alpha-galactosylceramide were not active for iNKT cells...