Minoru Yoshiyama

Summary

Affiliation: Osaka City University
Country: Japan

Publications

  1. ncbi request reprint Left ventricular remodeling after myocardial infarction in antecedent hypertensive patients
    Minoru Yoshiyama
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Hypertens Res 28:293-9. 2005
  2. pmc Angiotensin converting enzyme inhibitor prevents left ventricular remodelling after myocardial infarction in angiotensin II type 1 receptor knockout mice
    M Yoshiyama
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Heart 91:1080-5. 2005
  3. ncbi request reprint Convalescent stage coronary flow reserve and late myocardial morphologic outcomes in patients with first anterior acute myocardial infarction
    Yoshihisa Shimada
    Division of Cardiology, Tsukazaki Memorial Hospital, Hyogo, Japan
    Circ J 68:208-13. 2004
  4. ncbi request reprint Additive improvement of left ventricular remodeling by aldosterone receptor blockade with eplerenone and angiotensin II type 1 receptor antagonist in rats with myocardial infarction
    Minoru Yoshiyama
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Graduate School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Nihon Yakurigaku Zasshi 124:83-9. 2004
  5. ncbi request reprint Cardioprotective effect of SEA0400, a selective inhibitor of the Na(+)/Ca(2+) exchanger, on myocardial ischemia-reperfusion injury in rats
    Minoru Yoshiyama
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    J Pharmacol Sci 95:196-202. 2004
  6. ncbi request reprint Angiotensin blockade inhibits increased JNKs, AP-1 and NF- kappa B DNA-binding activities in myocardial infarcted rats
    M Yoshiyama
    Department of Medicine, Division of Cardiology, Osaka City University Medical School, Osaka, 545 8585, Japan
    J Mol Cell Cardiol 33:799-810. 2001
  7. pmc A case of a lesion containing an intracoronary thrombus detected as hyperintense plaque on T1-weighted cardiovascular magnetic resonance in a patient with silent myocardial ischemia
    Kenji Matsumoto
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Cardiovasc Magn Reson 15:50. 2013
  8. ncbi request reprint Effects of aldosterone receptor antagonist and angiotensin II type I receptor blocker on cardiac transcriptional factors and mRNA expression in rats with myocardial infarction
    Ryo Matsumoto
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Japan
    Circ J 68:376-82. 2004
  9. ncbi request reprint The long-acting Ca2+-channel blocker azelnidipine prevents left ventricular remodeling after myocardial infarction
    Daisuke Nishiya
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Asahimachi, Osaka, Japan
    J Pharmacol Sci 103:391-7. 2007
  10. doi request reprint Relationship of thrombus characteristics to the incidence of angiographically visible distal embolization in patients with ST-segment elevation myocardial infarction treated with thrombus aspiration
    Kei Yunoki
    Department of Cardiology, Osaka City General Hospital, Osaka, Japan
    JACC Cardiovasc Interv 6:377-85. 2013

Collaborators

Detail Information

Publications76

  1. ncbi request reprint Left ventricular remodeling after myocardial infarction in antecedent hypertensive patients
    Minoru Yoshiyama
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Hypertens Res 28:293-9. 2005
    ..The results demonstrated that antecedent hypertension interacts with ventricular cavity dilatation after MI...
  2. pmc Angiotensin converting enzyme inhibitor prevents left ventricular remodelling after myocardial infarction in angiotensin II type 1 receptor knockout mice
    M Yoshiyama
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Heart 91:1080-5. 2005
    ..However, it is still not clear whether inhibition of the AT1 receptor is enough to prevent LV remodelling after MI...
  3. ncbi request reprint Convalescent stage coronary flow reserve and late myocardial morphologic outcomes in patients with first anterior acute myocardial infarction
    Yoshihisa Shimada
    Division of Cardiology, Tsukazaki Memorial Hospital, Hyogo, Japan
    Circ J 68:208-13. 2004
    ..However, its recovery may vary among individuals and the relationship between convalescent stage microvasculature and late myocardial morphologic change is unclear...
  4. ncbi request reprint Additive improvement of left ventricular remodeling by aldosterone receptor blockade with eplerenone and angiotensin II type 1 receptor antagonist in rats with myocardial infarction
    Minoru Yoshiyama
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Graduate School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Nihon Yakurigaku Zasshi 124:83-9. 2004
    ..Combination therapy with an candesartan substantially potentiates this effect by a complementary prevention of LV fibrosis, cardiac hypertrophy, and molecular alterations...
  5. ncbi request reprint Cardioprotective effect of SEA0400, a selective inhibitor of the Na(+)/Ca(2+) exchanger, on myocardial ischemia-reperfusion injury in rats
    Minoru Yoshiyama
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    J Pharmacol Sci 95:196-202. 2004
    ..This study demonstrates that the NCX is an important mechanism for cell death in myocardial ischemia and reperfusion in rats. SEA0400 may prove to be a promising new drug in the clinical treatment of myocardial ischemia and reperfusion...
  6. ncbi request reprint Angiotensin blockade inhibits increased JNKs, AP-1 and NF- kappa B DNA-binding activities in myocardial infarcted rats
    M Yoshiyama
    Department of Medicine, Division of Cardiology, Osaka City University Medical School, Osaka, 545 8585, Japan
    J Mol Cell Cardiol 33:799-810. 2001
    ..JNKs, AP-1 and NF- kappa B activation in myocardial infarcted rats could be responsible for left ventricular remodeling after myocardial infarction and angiotensin may be related to the activation of these signals...
  7. pmc A case of a lesion containing an intracoronary thrombus detected as hyperintense plaque on T1-weighted cardiovascular magnetic resonance in a patient with silent myocardial ischemia
    Kenji Matsumoto
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Cardiovasc Magn Reson 15:50. 2013
    ..This article reports the case of a lesion containing an intracoronary thrombus, detected as HIP on T1WI associated with the filter no-reflow phenomenon in a patient with silent myocardial ischemia...
  8. ncbi request reprint Effects of aldosterone receptor antagonist and angiotensin II type I receptor blocker on cardiac transcriptional factors and mRNA expression in rats with myocardial infarction
    Ryo Matsumoto
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Japan
    Circ J 68:376-82. 2004
    ....
  9. ncbi request reprint The long-acting Ca2+-channel blocker azelnidipine prevents left ventricular remodeling after myocardial infarction
    Daisuke Nishiya
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Asahimachi, Osaka, Japan
    J Pharmacol Sci 103:391-7. 2007
    ..3 +/- 0.8, respectively). In conclusion, azelnidipine can prevent LV remodeling and improve systolic and diastolic function after MI. Administration of long-acting Ca(2+)-channel blockers after MI is an effective strategy for treating MI...
  10. doi request reprint Relationship of thrombus characteristics to the incidence of angiographically visible distal embolization in patients with ST-segment elevation myocardial infarction treated with thrombus aspiration
    Kei Yunoki
    Department of Cardiology, Osaka City General Hospital, Osaka, Japan
    JACC Cardiovasc Interv 6:377-85. 2013
    ....
  11. ncbi request reprint Impaired coronary circulation in patients with apical hypertrophic cardiomyopathy: noninvasive analysis by transthoracic Doppler echocardiography
    Ken Yoshida
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Echocardiography 22:723-9. 2005
    ..We designed this study to examine the characteristics of coronary circulation in patients with apical hypertrophic cardiomyopathy (ApHCM) using noninvasive transthoracic Doppler echocardiography (TTDE)...
  12. ncbi request reprint Functional mitral regurgitation predicts prognosis independent of left ventricular systolic and diastolic indices in patients with ischemic heart disease
    Hiroyuki Okura
    Division of Cardiology, Bell Land General Hospital, Sakai, Japan
    J Am Soc Echocardiogr 21:355-60. 2008
    ....
  13. ncbi request reprint Core protein of hepatitis C virus induces cardiomyopathy
    Takashi Omura
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Circ Res 96:148-50. 2005
    ..These histological changes are just consistent with cardiomyopathy. In conclusion, the HCV-core protein directly plays an important role in the development of cardiomyopathy...
  14. doi request reprint A prospective, multicenter, randomized trial to assess efficacy of pioglitazone on in-stent neointimal suppression in type 2 diabetes: POPPS (Prevention of In-Stent Neointimal Proliferation by Pioglitazone Study)
    Tsutomu Takagi
    Division of Cardiology, Takagi Cardiology Clinic, Kyoto, Japan
    JACC Cardiovasc Interv 2:524-31. 2009
    ..The aim of this study was to clarify whether pioglitazone suppresses in-stent neointimal proliferation and reduces restenosis and target lesion revascularization (TLR) after percutaneous coronary intervention (PCI)...
  15. ncbi request reprint Involvement of c-Jun NH2 terminal kinase and p38MAPK in rapamycin-mediated inhibition of neointimal formation in rat carotid arteries
    Takashi Omura
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    J Cardiovasc Pharmacol 46:519-25. 2005
    ..Therefore, we examined the effects of rapamycin on MAPK and transcriptional factors in cultured human coronary artery smooth muscle cells (CASMC) and in balloon-injured rat carotid arteries...
  16. ncbi request reprint Quantitative intravenous myocardial contrast echocardiography predicts recovery of left ventricular function after revascularization in chronic coronary artery disease
    Shota Fukuda
    Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, Osaka, Japan
    Echocardiography 21:119-24. 2004
    ..Quantitative intravenous myocardial contrast echocardiography (MCE) has been shown to measure regional myocardial blood flow velocity noninvasively...
  17. ncbi request reprint Beneficial effects of combination of ACE inhibitor and angiotensin II type 1 receptor blocker on cardiac remodeling in rat myocardial infarction
    Yasuhiro Nakamura
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Cardiovasc Res 57:48-54. 2003
    ..In this study, we compared the effects of an ACE inhibitor (temocapril), an ARB (CS-866), and their combination on cardiac remodeling after MI...
  18. ncbi request reprint Acute hyperglycemia induced by oral glucose loading suppresses coronary microcirculation on transthoracic Doppler echocardiography in healthy young adults
    Kohei Fujimoto
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Echocardiography 23:829-34. 2006
    ..We sought to evaluate the effect of acute hyperglycemia on coronary microcirculation by noninvasive measurement of coronary flow velocity reserve (CFVR) using transthoracic Doppler echocardiography (TTDE)...
  19. ncbi request reprint Angiotensin blockade inhibits osteopontin expression in non-infarcted myocardium after myocardial infarction
    Takanori Kusuyama
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Japan
    J Pharmacol Sci 98:283-9. 2005
    ..Both ACEI and ARB significantly prevented cardiac fibrosis and osteopontin expression. In conclusion, angiotensin blockade inhibits osteopontin expression in non-infarcted myocardium and prevents cardiac remodeling after MI...
  20. ncbi request reprint Effects of granulocyte-colony stimulating factor on cardiac remodeling after myocardial infarction
    Yasuhiro Takagi
    Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, 1 4 3, Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Osaka City Med J 51:43-50. 2005
    ..However, the effects of G-CSF on MI are still controversial and the molecular mechanism of G-CSF treatment for repair of the infarcted heart is not fully understood...
  21. ncbi request reprint New noninvasive diagnosis of myocardial ischemia of the left circumflex coronary artery using coronary flow reserve measurement by transthoracic Doppler echocardiography: comparison with thallium-201 single photon emission computed tomography
    Kohei Fujimoto
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Asahimachi 1 4 3, Abeno Ku, Osaka 545 8585
    J Cardiol 43:109-16. 2004
    ....
  22. ncbi request reprint Involvement of apoptosis signal-regulating kinase-1 on angiotensin II-induced monocyte chemoattractant protein-1 expression
    Takashi Omura
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Arterioscler Thromb Vasc Biol 24:270-5. 2004
    ..To elucidate these molecular mechanisms, angiotensin II-induced expression of MCP-1 was examined in cultured rat neonatal ventricular cardiomyocytes and fibroblasts by adenovirus gene transfer...
  23. ncbi request reprint Effects of erythropoietin on cardiac remodeling after myocardial infarction
    Daisuke Nishiya
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Asahimachi, Japan
    J Pharmacol Sci 101:31-9. 2006
    ..In conclusion, when administered after MI, EPO prevents cardiac remodeling and improves ventricular function with enhanced angiogenesis and reduced apoptosis...
  24. doi request reprint Utility of myocardial fractional flow reserve for prediction of restenosis following sirolimus-eluting stent implantation
    Hideshi Ishii
    Department of Cardiology, Higashisumiyoshi Morimoto Hospital, Osaka, Japan
    Heart Vessels 26:572-81. 2011
    ..81 ± 0.12 vs. non-restenosis 0.92 ± 0.06, p = 0.029). SES patients with restenosis had a lower FFR post stent deployment, suggesting the decreased FFR may be a useful predictor for SES restenosis...
  25. ncbi request reprint Peri-atrial epicardial adipose tissue is associated with new-onset nonvalvular atrial fibrillation
    Koki Nakanishi
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Circ J 76:2748-54. 2012
    ..Multidetector computed tomography (MDCT) can accurately assess EAT's volume and distribution. This study used MDCT to investigate the effect of peri-atrial EAT on new-onset nonvalvular AF...
  26. ncbi request reprint Endothelin-converting enzyme expression in the neointima after percutaneous coronary intervention
    Nobuyuki Shirai
    Department of Pathology, Osaka City University, Graduate School of Medicine, Japan
    Osaka City Med J 52:29-37. 2006
    ..These findings suggest that ECE is upregulated in the neointima at early stages after PCI injury. ECE may be one of the mediators in the repair processes after PCI in humans...
  27. doi request reprint Effects of intravenous atrial natriuretic peptide and nitroglycerin on coronary vasodilation and flow velocity determined using 3 T magnetic resonance imaging in patients with nonischemic heart failure
    Shoichi Ehara
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Heart Vessels 28:596-605. 2013
    ..Using this method, we showed that the effects of ANP on the coronary artery vasodilation and flow velocity were not inferior to those of NTG, with no significant alteration in heart rate. ..
  28. doi request reprint Impact of concomitant coronary artery disease on atherosclerotic plaques in the aortic arch in patients with severe aortic stenosis
    Suwako Fujita
    Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Cardiol 36:352-7. 2013
    ..However, the influence of concomitant CAD on the presence of atherosclerotic complex plaques in the aortic arch, which is associated with increased stroke risk, has not been fully assessed in patients with severe AS...
  29. ncbi request reprint Cut-off value of coronary flow velocity reserve by transthoracic Doppler echocardiography for diagnosis of significant left anterior descending artery stenosis in patients with coronary risk factors
    Yoshiki Matsumura
    Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, Osaka, Japan
    Am J Cardiol 92:1389-93. 2003
    ..A cut-off value <2.0 of CFVR by transthoracic Doppler echocardiography was adequate for the diagnosis of significant LAD stenosis in a population that included patients with coronary risk factors...
  30. ncbi request reprint Beneficial effect of candesartan on rat diastolic heart failure
    Ryotaro Wake
    Department of Pharmacology, Osaka City University Graduate School of Medical Sciences, Osaka 545 8585, Japan
    J Pharmacol Sci 98:372-9. 2005
    ..These results indicate that candesartan can improve diastolic dysfunction and may slow the progression of cardiac remodelling in DS rats with established DHF...
  31. ncbi request reprint Transmitral inflow pattern assessed by Doppler echocardiography in angiotensin II type 1A receptor knockout mice with myocardial infarction
    Yasuhiro Nakamura
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Circ J 66:192-6. 2002
    ..05). mRNA expressions of ANP, BNP, collagen I and collagen III in the non-infarcted LV and RV of KO-MI were significantly lower than WT-MI. In conclusion, transmitral inflow abnormalities in KO-MI were attenuated compared with WT-MI...
  32. ncbi request reprint Role of c-Jun NH2-terminal kinase in G-protein-coupled receptor agonist-induced cardiac plasminogen activator inhibitor-1 expression
    Takashi Omura
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Mol Cell Cardiol 38:583-92. 2005
    ..In conclusion, G-protein-coupled receptor agonist-induced PAI-1 expression is partially mediated through JNK activation...
  33. ncbi request reprint Effects of treatment for diabetes mellitus on circulating vascular progenitor cells
    Takanori Kusuyama
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Japan
    J Pharmacol Sci 102:96-102. 2006
    ..DM reduces the number of circulating EPCs and SMPCs according to its severity, and treatment of DM significantly increases the number of EPCs and SMPCs, which may be involved in angiogenesis and atherosclerosis in diabetes...
  34. ncbi request reprint Relation of early improvement in coronary flow reserve to late recovery of left ventricular function after beta-blocker therapy in patients with idiopathic dilated cardiomyopathy
    Kenichi Sugioka
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am Heart J 153:1080.e1-6. 2007
    ....
  35. doi request reprint Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase
    Yasukatsu Izumi
    Department of Pharmacology, Osaka City University Medical School, Osaka 545 8585, Japan
    Hypertens Res 32:675-9. 2009
    ..Such phosphorylation results in eNOS activation and angiogenesis, which provide a novel explanation for one of the pleiotropic effects of statins that is beneficial for angiogenesis...
  36. ncbi request reprint Coronary flow velocity reserve measurement in three major coronary arteries using transthoracic Doppler echocardiography
    Eriko Murata
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Echocardiography 23:279-86. 2006
    ..The purpose of this study was to evaluate the value of this method in three major coronary arteries for detecting myocardial ischemia in the clinical setting...
  37. ncbi request reprint Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarction
    Ryo Matsumoto
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Arterioscler Thromb Vasc Biol 25:1168-73. 2005
    ..We hypothesized that transplantation of VEGF-expressing MSCs could effectively treat acute myocardial infarction (MI) by providing enhanced cardioprotection, followed by angiogenic effects in salvaging ischemic myocardium...
  38. doi request reprint Comprehensive evaluation of the apex beat using 64-slice computed tomography: Impact of left ventricular mass and distance to chest wall
    Shoichi Ehara
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Cardiol 55:256-65. 2010
    ..The aim of this study was to evaluate the relationships among presence, location, and sustained or double apical impulse of apex beat and LV function, volume, mass, and distance from heart to chest wall determined by MSCT...
  39. ncbi request reprint Impact of electrocardiographic left ventricular hypertrophy on the occurrence of cardiovascular events in elderly hypertensive patients. - The Japanese trial to assess optimal systolic blood pressure in elderly hypertensive patients (JATOS) -
    Satoshi Jissho
    Department of Internal Medicine and Cardiology, Osaka Ekisaikai Hospital, Osaka, Japan
    Circ J 74:938-45. 2010
    ..However, few studies have assessed risks associated with LVH in elderly hypertensive patients...
  40. ncbi request reprint Effect of azithromycin therapy on coronary circulation in patients with coronary artery disease
    Eiichi Hyodo
    Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, Osaka, Japan
    Am J Cardiol 94:1426-9. 2004
    ..0 +/- 0.7 vs 3.5 +/- 0.7, p <0.001). The changes in CFVR were negatively correlated with changes in high-sensitivity C-reactive protein levels in patients receiving azithromycin...
  41. doi request reprint The antifibrotic agent pirfenidone inhibits angiotensin II-induced cardiac hypertrophy in mice
    Takanori Yamazaki
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Hypertens Res 35:34-40. 2012
    ..Furthermore, the expression of mineralocorticoid receptors was attenuated by pirfenidone. These results indicate that pirfenidone might be effective as an antifibrotic drug in the treatment of cardiac hypertrophy induced by hypertension...
  42. ncbi request reprint Assessment of aortic atheromatous plaque and stiffness by 64-slice computed tomography is useful for identifying patients with coronary artery disease
    Takuhiro Okuyama
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Circ J 72:2021-7. 2008
    ..Using MSCT, atherosis and sclerosis of the descending thoracic aorta (DTA) were quantified and differences between patients with and without coronary artery disease (CAD) were analyzed...
  43. ncbi request reprint Elevated plasma levels of oxidized low-density lipoprotein relate to the presence of angiographically detected complex and thrombotic coronary artery lesion morphology in patients with unstable angina
    Hajime Yamashita
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Circ J 71:681-7. 2007
    ....
  44. ncbi request reprint Automated three-dimensional analysis of mitral annular dynamics in patients with myocardial infarction using automated mitral annular tracking method
    Yasuhiko Takemoto
    Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, Osaka, Japan
    Echocardiography 23:658-65. 2006
    ..A newly developed automated mitral annular tracking method (AMAT) has recently become available and enables us to perform automated analysis of mitral annular dynamics...
  45. ncbi request reprint Tolvaptan attenuates left ventricular fibrosis after acute myocardial infarction in rats
    Takanori Yamazaki
    Department of Cardiovascular Medicine, Osaka City University Medical School, Japan
    J Pharmacol Sci 123:58-66. 2013
    ..The combination treatment also repressed MI-induced mineralocorticoid receptor expression. Tolvaptan, or combination of furosemide and tolvaptan, may improve cardiac function in acute MI...
  46. ncbi request reprint Role of contrast-enhanced dobutamine stress echocardiography in predicting outcome in patients with known or suspected coronary artery disease
    Ryotaro Wake
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Echocardiography 23:642-9. 2006
    ..5 (P < 0.0001, HR: 6.65) and age > 70 years (P < 0.005, HR: 3.27). We conclude that contrast-enhanced DSE provides important prognostic information for future cardiac events...
  47. ncbi request reprint Cut-off value of coronary flow velocity reserve by transthoracic Doppler echocardiography for the assessment of significant donor left anterior descending artery stenosis in patients with spontaneously visible collaterals
    Shinichi Iwata
    The Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Am J Cardiol 98:298-302. 2006
    ..However, a cut-off value < 2.0 was appropriate for the diagnosis of significant donor left anterior descending artery stenosis in a population that included patients with collaterals...
  48. ncbi request reprint Clinical use of Doppler echocardiography and Doppler tissue imaging in the estimation of myocardial ischemia during dobutamine stress echocardiography
    Eiichi Hyodo
    Department of Internal Medicine, Division of Cardiology, Higashisumisyoshi Morimoto Hospital, Osaka, Japan
    J Am Soc Echocardiogr 21:331-6. 2008
    ..The ratio of mitral inflow early diastolic velocity (E) to annulus velocity (E') might be critical for the assessment of an abnormal filling pressure for patients with myocardial ischemia...
  49. doi request reprint Erythrocyte-rich thrombus aspirated from patients with ST-elevation myocardial infarction: association with oxidative stress and its impact on myocardial reperfusion
    Kei Yunoki
    Department of Cardiology, Osaka City General Hospital, Osaka, Japan
    Eur Heart J 33:1480-90. 2012
    ..The purpose of this study was to determine the associations of red blood cell (RBC) component of coronary thrombi with oxidative stress and myocardial reperfusion...
  50. ncbi request reprint Granulocyte-colony stimulating factor augments neovascularization induced by bone marrow transplantation in rat hindlimb ischemia
    Yasuhiro Takagi
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medical Sciences, Osaka, Japan
    J Pharmacol Sci 99:45-51. 2005
    ..In conclusion, G-CSF was found to augment neovascularization in rat hindlimb ischemia. Combined use of G-CSF treatment and BMT may be a useful strategy for therapeutic neovascularization in ischemic tissues...
  51. ncbi request reprint Noninvasive coronary flow velocity reserve measurement in the posterior descending coronary artery for detecting coronary stenosis in the right coronary artery using contrast-enhanced transthoracic Doppler echocardiography
    Hiroyuki Watanabe
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    Echocardiography 21:225-33. 2004
    ..However, this method has been restricted only for the LAD. The purpose of this study was to detect severe right coronary artery (RCA) stenosis by CFVR measurement using contrast-enhanced TTDE...
  52. doi request reprint Impact of lesion length on functional significance in intermediate coronary lesions
    Tomokazu Iguchi
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Clin Cardiol 36:172-7. 2013
    ..Myocardial fractional flow reserve (FFR) is useful in the evaluation of coronary lesion ischemia. However, the impact of lesion length on FFR has not been adequately assessed...
  53. doi request reprint Typical coronary appearance of dilated cardiomyopathy versus left ventricular concentric hypertrophy: coronary volumes measured by multislice computed tomography
    Shoichi Ehara
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Heart Vessels 28:188-98. 2013
    ..0005). This study showed that the increase in the coronary artery volume in patients with LVCH matched the increase in LV mass, but a decreased coronary volume with regard to LV mass was characteristic of patients with DCM...
  54. doi request reprint Gender-specific correlation between plasma myeloperoxidase levels and serum high-density lipoprotein-associated paraoxonase-1 levels in patients with stable and unstable coronary artery disease
    Kei Yunoki
    Department of Cardiology, Osaka City General Hospital, Osaka, Japan
    Atherosclerosis 231:308-14. 2013
    ..This study investigated the relationship between plasma MPO and serum PON-1 levels in patients with stable (SAP) and unstable angina pectoris (UAP)...
  55. ncbi request reprint Method analysis for optimal continuous imaging using intravascular optical coherence tomography
    Koichiro Asawa
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Asahimachi 1 4 3, Abeno Ku, Osaka 545 8585
    J Cardiol 47:133-41. 2006
    ..Continuous imaging methods have not been established. This study investigated optimal methods for continuous OCT imaging...
  56. ncbi request reprint Myeloperoxidase and progression of aortic valve stenosis in patients undergoing hemodialysis
    Satoko Wada
    Department of Pathology, City University Graduate School of Medicine, Osaka, Japan
    J Heart Valve Dis 22:640-7. 2013
    ..The study aim was to examine, immunohistochemically, the expression of MPO, using surgically resected aortic valve specimens from AS patients undergoing HD...
  57. ncbi request reprint Activation of apoptosis signal-regulating kinase 1 in injured artery and its critical role in neointimal hyperplasia
    Yasukatsu Izumi
    Department of Pharmacology, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno, Osaka 545 8585, Japan
    Circulation 108:2812-8. 2003
    ..Therefore, we first examined the role of ASK1 in vascular remodeling...
  58. doi request reprint Relation of elevated levels of plasma myeloperoxidase to impaired myocardial microcirculation after reperfusion in patients with acute myocardial infarction
    Kei Yunoki
    Department of Cardiology, Osaka City General Hospital, Osaka, Japan
    Am J Cardiol 105:922-9. 2010
    ..94, 95% confidence interval 2.10 to 22.9, p = 0.0015). In conclusion, elevated plasma MPO levels at admission were associated with impaired myocardial microcirculation after reperfusion in patients with acute myocardial infarction...
  59. ncbi request reprint Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration via oxidative stress
    Kaoru Yoshida
    Department of Pharmacology, Osaka City University Graduate School of Medical Science, Osaka, Japan
    Hypertens Res 28:447-55. 2005
    ..Aldosterone seems to induce cardiac inflammation and gene expression via oxidative stress that is inhibited by N-acetylcysteine but not by tempol...
  60. doi request reprint Napkin-ring sign on coronary CT angiography for the prediction of acute coronary syndrome
    Kenichiro Otsuka
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    JACC Cardiovasc Imaging 6:448-57. 2013
    ..The aim of this study was to determine the predictive value of the napkin-ring sign on coronary computed tomography angiography (CTA) for future acute coronary syndrome (ACS) events in patients with coronary artery disease...
  61. doi request reprint Elevated levels of neopterin are associated with carotid plaques with complex morphology in patients with stable angina pectoris
    Kenichi Sugioka
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Atherosclerosis 208:524-30. 2010
    ..We investigated the possible association between neopterin and complex carotid plaques which may be associated with the risk of ischemic stroke in patients with stable angina pectoris (SAP)...
  62. ncbi request reprint Incremental value of assessment of regional wall motion for detection of multivessel coronary artery disease in exercise (201)Tl gated myocardial perfusion imaging
    Naoya Shirai
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Nucl Med 43:443-50. 2002
    ....
  63. ncbi request reprint Effects of cellular cardiomyoplasty on ventricular remodeling assessed by Doppler echocardiography and topographic immunohistochemistry
    Minoru Yoshiyama
    Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Japan
    Circ J 68:580-6. 2004
    ....
  64. ncbi request reprint Spotty calcification typifies the culprit plaque in patients with acute myocardial infarction: an intravascular ultrasound study
    Shoichi Ehara
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Circulation 110:3424-9. 2004
    ....
  65. ncbi request reprint Antecedent hypertension interacts with adverse ventricular remodeling after myocardial infarction
    Kimio Kamimori
    Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, Japan
    Osaka City Med J 50:53-9. 2004
    ..The purpose of this study is to assess the relationship of antecedent hypertension to ventricular remodeling after MI...
  66. ncbi request reprint Comparison of levels of serum matrix metalloproteinase-9 in patients with acute myocardial infarction versus unstable angina pectoris versus stable angina pectoris
    Daiju Fukuda
    Department of Internal Medicine, Cardiology Graduate School of Medicine, Osaka City University Medical School, Osaka, Japan
    Am J Cardiol 97:175-80. 2006
    ..004). In conclusion, high levels of MMP-9 in patients who have AMI and UAP are related to the presence of plaque rupture in the culprit lesion...
  67. ncbi request reprint Acute myocardial infarction: clinical characteristics and plaque morphology between expansive remodeling and constrictive remodeling by intravascular ultrasound
    Takao Hasegawa
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am Heart J 151:332-7. 2006
    ..The purpose of this study is to investigate the difference between ER and CR at the culprit lesion in patients with acute myocardial infarction (AMI)...
  68. ncbi request reprint Comparison of clinical characteristics and arterial remodeling by intravascular ultrasonic imaging in three age groups (< or =55, 56 to 69 and > or =70 years) of Japanese patients with acute myocardial infarction
    Shoichi Ehara
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Cardiol 100:1713-7. 2007
    ..The differences in arterial remodeling of the culprit lesions between younger and older patients with AMIs may reflect different biologic mechanisms of plaque activation and destabilization...
  69. doi request reprint Usefulness of three-dimensional automated quantification of left ventricular mass, volume, and function by 64-slice computed tomography
    Takuhiro Okuyama
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Cardiol 52:276-84. 2008
    ..This study evaluated this new 3D automated method for measurement of LV mass, by comparison with a well-established 2D manual contour-drawing algorithm...
  70. doi request reprint Automated assessment of left atrial function from time-left atrial volume curves using a novel speckle tracking imaging method
    Keitaro Ogawa
    Department of Internal Medicine and Cardiology, Osaka City University Medical School, Osaka, Japan
    J Am Soc Echocardiogr 22:63-9. 2009
    ..Using a novel speckle-tracking imaging method, time-left atrial (LA) volume curves (TLAVCs) can be automatically obtained. The aim of this study was to evaluate whether this method can be used for the measurement of LA function with TLAVCs...
  71. doi request reprint Comparison of determinations of left atrial volume by the biplane area-length and Simpson's methods using 64-slice computed tomography
    Yasuhiro Takagi
    Department of Internal Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Cardiol 53:257-64. 2009
    ..The aim of this study was to determine whether there is a difference in results of quantification of LA volume by the area-length and Simpson's methods using multislice computed tomography (MSCT)...
  72. doi request reprint Circadian variation in coronary flow velocity reserve and its relation to α1-sympathetic activity in humans
    Shota Fukuda
    Department of Medicine, Osaka Ekisaikai Hospital, Osaka, Japan
    Int J Cardiol 157:216-20. 2012
    ..Recent advances in transthoracic Doppler echocardiography (TTDE) provide noninvasive, physiological assessment of coronary flow velocity reserve (CFVR)...
  73. ncbi request reprint Inadequate increase in the volume of major epicardial coronary arteries compared with that in left ventricular mass. Novel concept for characterization of coronary arteries using 64-slice computed tomography
    Shoichi Ehara
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Circ J 73:1448-53. 2009
    ..In the present study, measurements of CAV by 64-multislice computed tomography (MSCT) were validated and the relationship between CAV and LV mass was investigated...
  74. doi request reprint Transnasal transesophageal echocardiography in the detection of left atrial thrombus
    Shota Fukuda
    Department of Medicine, Cardiovascular Division, Osaka Ekisaikai Hospital, 2 1 10 Honden, Nishi ku, Osaka 550 0022, Japan
    J Cardiol 54:425-31. 2009
    ..We aimed to investigate the feasibility and safety of transnasal TEE in the detection of possible embolic sources in patients with atrial fibrillation (AF) and/or stroke, using an ultrathin TEE probe...
  75. ncbi request reprint Effects of gender on prognosis of patients with known or suspected coronary artery disease undergoing contrast-enhanced dobutamine stress echocardiography
    Ryotaro Wake
    Department of Cardiology and Internal Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Circ J 71:1060-6. 2007
    ..Gender differences in the predictors of outcome among patients with known or suspected coronary artery disease (CAD) undergoing contrast-enhanced dobutamine stress echocardiography (CE-DSE) have not been completely determined...
  76. ncbi request reprint Impaired coronary flow reserve as a marker of microvascular dysfunction to predict long-term cardiovascular outcomes, acute coronary syndrome and the development of heart failure
    Koki Nakanishi
    Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Circ J 76:1958-64. 2012
    ..This study aimed to assess the prognostic value of TTDE-derived CFR (as a marker of microvascular function) in predicting long-term cardiovascular events, acute coronary syndrome (ACS) events, and the development of heart failure (HF)...