Shigekiyo Matsumoto

Summary

Affiliation: Oita University
Country: Japan

Publications

  1. doi request reprint The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury: an electron spin resonance study
    Shigekiyo Matsumoto
    Department of Anaesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Trauma 68:796-801. 2010
  2. doi request reprint An electron spin resonance study for real-time detection of ascorbyl free radicals after addition of dimethyl sulfoxide in murine hippocampus or plasma during kainic acid-induced seizures
    Shigekiyo Matsumoto
    Department of Anaesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi Yufu, City Oita, 879 5593, Japan
    Neurochem Res 35:1010-6. 2010
  3. doi request reprint EPCK1, a vitamin C and E analogue, reduces endotoxin-induced systemic inflammation in mice
    Chihiro Shingu
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:719-25. 2011
  4. ncbi request reprint Association between heat stress protein 70 induction and decreased pulmonary fibrosis in an animal model of acute lung injury
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasamamachi, Yufu City, Oita, 879 5593, Japan
    Lung 185:287-93. 2007
  5. doi request reprint Human atrial natriuretic peptide attenuates renal ischemia-reperfusion injury
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 173:348-53. 2012
  6. ncbi request reprint Introduction of antisense oligonucleotides to heat shock protein 47 prevents pulmonary fibrosis in lipopolysaccharide-induced pneumopathy of the rat
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi, Yufu City, Oita 879 5593, Japan
    Eur J Pharmacol 564:174-80. 2007
  7. ncbi request reprint High dose antithrombin III inhibits HMGB1 and improves endotoxin-induced acute lung injury in rats
    Satoshi Hagiwara
    Oita University Faculty of Medicine, Department of Brain and Nerve Science, Anesthesiology, 1 1 Idaigaoka, Hasamamachi, Yufu City, Oita 879 5593, Japan
    Intensive Care Med 34:361-7. 2008
  8. ncbi request reprint Effects of gamma ray irradiation on energy metabolism in the rat brain: a 31P nuclear magnetic resonance spectroscopy study
    Osamu Tokumaru
    Department of Physiology, School of Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Neurosurg 105:202-7. 2006
  9. doi request reprint Human atrial natriuretic peptide ameliorates LPS-induced acute lung injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Oita University, 1 1 Idaigaoka Hasamamachi, Yufu City, Oita, 879 5593, Japan
    Lung 188:241-6. 2010
  10. doi request reprint Heat shock protein 72 protects insulin-secreting beta cells from lipopolysaccharide-induced endoplasmic reticulum stress
    Satoshi Hagiwara
    Department of Anaesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    Int J Hyperthermia 25:626-33. 2009

Detail Information

Publications28

  1. doi request reprint The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury: an electron spin resonance study
    Shigekiyo Matsumoto
    Department of Anaesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Trauma 68:796-801. 2010
    ..Variable baseline levels of oxidative stress in patients with ALI have been proposed as one explanation for inconsistent results...
  2. doi request reprint An electron spin resonance study for real-time detection of ascorbyl free radicals after addition of dimethyl sulfoxide in murine hippocampus or plasma during kainic acid-induced seizures
    Shigekiyo Matsumoto
    Department of Anaesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi Yufu, City Oita, 879 5593, Japan
    Neurochem Res 35:1010-6. 2010
    ..Due to the simplicity, good performance, low cost and real-time monitoring of ascorbate, this method may be applied to clinical research and treatment in the future...
  3. doi request reprint EPCK1, a vitamin C and E analogue, reduces endotoxin-induced systemic inflammation in mice
    Chihiro Shingu
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:719-25. 2011
    ..In the current study, we tested whether EPCK1 inhibits oxidative stress and prevents systemic inflammation...
  4. ncbi request reprint Association between heat stress protein 70 induction and decreased pulmonary fibrosis in an animal model of acute lung injury
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasamamachi, Yufu City, Oita, 879 5593, Japan
    Lung 185:287-93. 2007
    ..These data indicate that thermal pretreatment is associated with the induction of HSP70 protein synthesis, which subsequently attenuates tissue damage in experimental lung fibrosis...
  5. doi request reprint Human atrial natriuretic peptide attenuates renal ischemia-reperfusion injury
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 173:348-53. 2012
    ..Human atrial natriuretic peptide (hANP) exerts various pharmacologic effects, including renal protection. In the present study, we evaluated the renal protective effect of hANP in a rat model of renal I/R...
  6. ncbi request reprint Introduction of antisense oligonucleotides to heat shock protein 47 prevents pulmonary fibrosis in lipopolysaccharide-induced pneumopathy of the rat
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi, Yufu City, Oita 879 5593, Japan
    Eur J Pharmacol 564:174-80. 2007
    ..These findings suggest that HSP 47 antisense oligonucleotides improve lung fibrosis among rats with LPS-induced pneumopathy...
  7. ncbi request reprint High dose antithrombin III inhibits HMGB1 and improves endotoxin-induced acute lung injury in rats
    Satoshi Hagiwara
    Oita University Faculty of Medicine, Department of Brain and Nerve Science, Anesthesiology, 1 1 Idaigaoka, Hasamamachi, Yufu City, Oita 879 5593, Japan
    Intensive Care Med 34:361-7. 2008
    ..High mobility group box 1 (HMGB1) is an important factor in the development of sepsis. Previous work suggests that antithrombin III (ATIII) inhibits inflammation, but the mechanism of action is still poorly understood...
  8. ncbi request reprint Effects of gamma ray irradiation on energy metabolism in the rat brain: a 31P nuclear magnetic resonance spectroscopy study
    Osamu Tokumaru
    Department of Physiology, School of Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Neurosurg 105:202-7. 2006
    ..The purpose of the present study was to investigate the effects of gamma irradiation on energy metabolism in the rat brain by using 31P nuclear magnetic resonance spectroscopy (31P-NMRS)...
  9. doi request reprint Human atrial natriuretic peptide ameliorates LPS-induced acute lung injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Oita University, 1 1 Idaigaoka Hasamamachi, Yufu City, Oita, 879 5593, Japan
    Lung 188:241-6. 2010
    ..Taken together, these data demonstrate that hANP exerts an anti-inflammatory effect and may have potential as a therapeutic agent to treat systemic inflammatory diseases...
  10. doi request reprint Heat shock protein 72 protects insulin-secreting beta cells from lipopolysaccharide-induced endoplasmic reticulum stress
    Satoshi Hagiwara
    Department of Anaesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    Int J Hyperthermia 25:626-33. 2009
    ..Given that systemic-inflammation induces ER stress, we further examined whether hyperthermia can attenuate the extent of LPS-induced ER stress...
  11. doi request reprint Sivelestat treatment for acute respiratory distress syndrome in an infant
    Shigekiyo Matsumoto
    Department of Brain and Nerve Science and Department of Anesthesiology, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Yufu, Oita, 879 5593, Japan
    J Anesth 23:288-91. 2009
    ..Our experience suggests that intravenous sivelestat offers a new therapeutic strategy for infantile ARDS/ALI, but further investigation of the indication, administration period, and dosage is required...
  12. doi request reprint Danaparoid sodium attenuates the effects of heat stress
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:762-8. 2011
    ..Given that heat stroke is a severe inflammatory response disease, we hypothesized that DA could inhibit inflammation from heat stress and prevent acute heat stroke...
  13. doi request reprint Hydrogen-rich saline solution attenuates renal ischemia-reperfusion injury
    Chihiro Shingu
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasamamachi, Yufu, Oita, 879 5593, Japan
    J Anesth 24:569-74. 2010
    ..A recent study has shown that hydrogen has antioxidant properties. In this study, we tested the hypothesis that a hydrogen-rich saline solution (HRSS) attenuates renal I/R injury in a rodent model...
  14. doi request reprint In vivo and in vitro effects of the anticoagulant, thrombomodulin, on the inflammatory response in rodent models
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Oita University, 1 1 Idaigaoka Hasamamachi Yufu, Oita City, 879 5593, Japan
    Shock 33:282-8. 2010
    ..Given these results, rTM is a strong candidate as a therapeutic agent for various systemic inflammatory diseases...
  15. ncbi request reprint An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Yufu City, Oita 879 5593, Japan
    Toxicology 236:199-207. 2007
    ..An immunoblot analysis confirmed that the HSP47-antisense oligonucleotide inhibited HSP47 production. These findings indicate that the HSP47-antisense oligonucleotide inhibited paraquat-induced pulmonary fibrosis and pneumopathy in rats...
  16. doi request reprint ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:734-41. 2011
    ..We investigated whether the new anti-oxidative drug, ETS-GS, could inhibit secretion of cytokines and mono-nitrogen oxides, thus reducing organ damage in a rat model of lipopolysaccharide-induced sepsis...
  17. ncbi request reprint Effect of enteral versus parenteral nutrition on LPS-induced sepsis in a rat model
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, Oita, Japan
    J Surg Res 145:251-6. 2008
    ..The purpose of the present study was to determine whether total enteral nutrition (TEN) or total parenteral nutrition (TPN) differ in their modulation of ghrelin production and cardiac dysfunction induced by lipopolysaccharide (LPS)...
  18. doi request reprint Anesthetic management of a patient with hyperthyroidism due to hydatidiform mole
    Shigekiyo Matsumoto
    Department of Anesthesiology and Intensive Care Medicine, Yufu, Oita, Japan
    J Anesth 23:594-6. 2009
    ..The patient became euthyroid within a few days after mole evacuation and did not require an antiarrhythmic agent after her return to the inpatient ward...
  19. pmc Antisense oligonucleotide inhibition of heat shock protein (HSP) 47 improves bleomycin-induced pulmonary fibrosis in rats
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, Idaigaoka Hasamamachi Yufu City Oita, Japan
    Respir Res 8:37. 2007
    ..The 47 kDa heat shock protein 47 (HSP47) is a collagen-specific molecular chaperone that has been shown to play a major role during the processing and/or secretion of procollagen...
  20. doi request reprint New evaluation of fetal oxidative stress: measurement of the umbilical cord blood dimethyl sulfate-induced ascorbyl free radical by an electron spin resonance method
    Yoshihiro Nishida
    Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Oita, Japan
    J Matern Fetal Neonatal Med 25:2499-502. 2012
    ..The aim is to evaluate intrapartum fetal oxidative stress in real-time by umbilical cord blood dimethyl sulfate (DMSO)-induced ascorbyl free radical (AFR) measured by an electron spin resonance (ESR) method...
  21. doi request reprint Catecholamine-resistant shock and hypoglycemic coma after cardiotomy in a patient with unexpected isolated ACTH deficiency
    Shigekiyo Matsumoto
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi, Yufu, Oita, 879 5593, Japan
    J Anesth 25:431-4. 2011
    ..Therefore, cortisol must be supplemented without delay when acute adrenal insufficiency is suspected during the perioperative period...
  22. doi request reprint Uncoupling of peripheral and master clock gene rhythms by reversed feeding leads to an exacerbated inflammatory response after polymicrobial sepsis in mice
    Yoshimasa Oyama
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine and Department of Anesthesiology, Almeida Memorial Hospital, Oita, Japan
    Shock 41:214-21. 2014
    ..Our findings suggest that uncoupling of peripheral and master clock gene rhythms by reversed feeding exacerbates inflammatory responses. ..
  23. pmc Use of perioperative ureteral stent in abdominal aortic aneurysm with retroperitoneal fibrosis - A report of two cases -
    Junya Kusaka
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    Korean J Anesthesiol 63:76-9. 2012
    ..The clinical course of these cases suggests that, in laparotomy with concomitant retroperitoneal fibrosis, preoperative ureteral stent placement can prevent postoperative complications in the renal and urinary systems...
  24. doi request reprint Herpes simplex virus pneumonia following mitral valve replacement
    Akiko Yamaguchi
    Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Oita University, 1 1 Hasamamachi, Yufu, Oita, 879 5593, Japan
    Gen Thorac Cardiovasc Surg 58:580-3. 2010
    ..Physicians should consider viral pulmonary infection to be a potential cause of unexplained hypoxemia that does not respond to conventional antibiotic treatment in critically ill, immunocompromised patients...
  25. doi request reprint ETS-GS, a new antioxidant, ameliorates renal ischemia-reperfusion injury in a rodent model
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Surg Res 171:226-33. 2011
    ..The current study examined whether a new antioxidant, ETS-GS, inhibits reactive oxygen species (ROS) generation and thereby prevents renal I/R injury in rodent models...
  26. doi request reprint Neuroprotective effects of ethyl pyruvate on brain energy metabolism after ischemia-reperfusion injury: a 31P-nuclear magnetic resonance study
    Osamu Tokumaru
    Department of Physiology, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Yufu, Oita, 879 5593, Japan
    Neurochem Res 34:775-85. 2009
    ..We suggest the potential involvement of multiple mechanisms of action, such as less acidic intracellular pH, glial production of lactate, and radical scavenging ability...
  27. ncbi request reprint Coexpression of HSP47 gene and type I and type III collagen genes in LPS-induced pulmonary fibrosis in rats
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi, Yufu City, Oita, 879 5593, Japan
    Lung 185:31-7. 2007
    ..These results suggest that the upregulation of HSP47 and collagen may play an important role in the fibrotic process of LPS-induced ARDS lung...
  28. ncbi request reprint Monocarboxylates and glucose utilization as energy substrates in rat brain slices under selective glial poisoning--a 31P NMR study
    Takaaki Kitano
    Department of Anesthesiology, Faculty of Medicine, Oita Medical University, Oita Gun, Oita, Japan
    Mol Cell Biochem 244:77-81. 2003
    ..This indicates that after the preconditioning, such as ischemia, neurons themselves acquired the ability to utilize lactate as an energy substrate...