Hironori Koga

Summary

Affiliation: Oita University
Country: Japan

Publications

  1. doi request reprint Human atrial natriuretic peptide ameliorates LPS-induced acute lung injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Oita University, 1 1 Idaigaoka Hasamamachi, Yufu City, Oita, 879 5593, Japan
    Lung 188:241-6. 2010
  2. doi request reprint EPCK1, a vitamin C and E analogue, reduces endotoxin-induced systemic inflammation in mice
    Chihiro Shingu
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:719-25. 2011
  3. doi request reprint ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:734-41. 2011
  4. doi request reprint ETS-GS, a new antioxidant, ameliorates renal ischemia-reperfusion injury in a rodent model
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Surg Res 171:226-33. 2011
  5. doi request reprint New α-lipoic acid derivative, DHL-HisZn, ameliorates renal ischemia-reperfusion injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University, Faculty of Medicine, Oita, Japan
    J Surg Res 174:352-8. 2012
  6. doi request reprint Human atrial natriuretic peptide attenuates renal ischemia-reperfusion injury
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 173:348-53. 2012
  7. doi request reprint Age-dependent responses to renal ischemia-reperfusion injury
    Junya Kusaka
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 172:153-8. 2012
  8. doi request reprint The vitamin E derivative, ESeroS-GS, attenuates renal ischemia-reperfusion injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 176:220-5. 2012
  9. doi request reprint Anti-inflammatory effects of perioperative intensive insulin therapy during cardiac surgery with cardiopulmonary bypass
    Akira Hasegawa
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi, Yufu, Oita, 879 5593, Japan
    Surg Today 41:1385-90. 2011
  10. doi request reprint Cepharanthine improves renal ischemia-reperfusion injury in rats
    Junya Kusaka
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:212-7. 2011

Collaborators

Detail Information

Publications24

  1. doi request reprint Human atrial natriuretic peptide ameliorates LPS-induced acute lung injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Oita University, 1 1 Idaigaoka Hasamamachi, Yufu City, Oita, 879 5593, Japan
    Lung 188:241-6. 2010
    ..Taken together, these data demonstrate that hANP exerts an anti-inflammatory effect and may have potential as a therapeutic agent to treat systemic inflammatory diseases...
  2. doi request reprint EPCK1, a vitamin C and E analogue, reduces endotoxin-induced systemic inflammation in mice
    Chihiro Shingu
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:719-25. 2011
    ..In the current study, we tested whether EPCK1 inhibits oxidative stress and prevents systemic inflammation...
  3. doi request reprint ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:734-41. 2011
    ..We investigated whether the new anti-oxidative drug, ETS-GS, could inhibit secretion of cytokines and mono-nitrogen oxides, thus reducing organ damage in a rat model of lipopolysaccharide-induced sepsis...
  4. doi request reprint ETS-GS, a new antioxidant, ameliorates renal ischemia-reperfusion injury in a rodent model
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Surg Res 171:226-33. 2011
    ..The current study examined whether a new antioxidant, ETS-GS, inhibits reactive oxygen species (ROS) generation and thereby prevents renal I/R injury in rodent models...
  5. doi request reprint New α-lipoic acid derivative, DHL-HisZn, ameliorates renal ischemia-reperfusion injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University, Faculty of Medicine, Oita, Japan
    J Surg Res 174:352-8. 2012
    ..The present study evaluated the ability of DHL-HisZn, a new α-lipoic acid derivative, to inhibit ROS generation and prevent renal I/R injury in rats...
  6. doi request reprint Human atrial natriuretic peptide attenuates renal ischemia-reperfusion injury
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 173:348-53. 2012
    ..Human atrial natriuretic peptide (hANP) exerts various pharmacologic effects, including renal protection. In the present study, we evaluated the renal protective effect of hANP in a rat model of renal I/R...
  7. doi request reprint Age-dependent responses to renal ischemia-reperfusion injury
    Junya Kusaka
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 172:153-8. 2012
    ..In the present study, we assessed kidney morphology, function, and oxidative stress in young and aged rats after renal ischemia and reperfusion...
  8. doi request reprint The vitamin E derivative, ESeroS-GS, attenuates renal ischemia-reperfusion injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 176:220-5. 2012
    ..In this study, we hypothesized that ESeroS-GS, a vitamin E derivative, inhibits cytokine production and prevents renal ischemia-reperfusion (I/R) injury in rats...
  9. doi request reprint Anti-inflammatory effects of perioperative intensive insulin therapy during cardiac surgery with cardiopulmonary bypass
    Akira Hasegawa
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi, Yufu, Oita, 879 5593, Japan
    Surg Today 41:1385-90. 2011
    ..In the present study, we evaluated how perioperative intensive insulin therapy (IIT) influences the inflammatory response in an artificial pancreas during cardiac surgery with cardiopulmonary bypass...
  10. doi request reprint Cepharanthine improves renal ischemia-reperfusion injury in rats
    Junya Kusaka
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:212-7. 2011
    ..In this study, we examined whether cepharanthine provides a renal-protective effect in a renal ischemia-reperfusion model...
  11. doi request reprint The new vitamin E derivative, ETS-GS, protects against cecal ligation and puncture-induced systemic inflammation in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi, Yufu City, Oita 879 5593, Japan
    Inflammation 35:545-53. 2012
    ..This mechanism appeared to be mediated by the induction of PI3K-Akt and the inhibition of IκBα and MAPK phosphorylation. Given these results, ETS-GS shows promise as a potential therapeutic agent for sepsis...
  12. doi request reprint Vitamin E derivative ETS-GS reduces liver ischemia-reperfusion injury in rats
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Surg Res 175:118-22. 2012
    ..Recent studies have reported that vitamin E and glutathione can ameliorate ischemia-reperfusion (I/R) injury. In the present study, we evaluated the ability of a new vitamin E derivative, ETS-GS, to improve liver I/R injury...
  13. doi request reprint An electron spin resonance study for real-time detection of ascorbyl free radicals after addition of dimethyl sulfoxide in murine hippocampus or plasma during kainic acid-induced seizures
    Shigekiyo Matsumoto
    Department of Anaesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi Yufu, City Oita, 879 5593, Japan
    Neurochem Res 35:1010-6. 2010
    ..Due to the simplicity, good performance, low cost and real-time monitoring of ascorbate, this method may be applied to clinical research and treatment in the future...
  14. doi request reprint Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation
    Kyosuke Kudo
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Surg Res 171:199-204. 2011
    ..In the present study, we investigated protective effects of CE in a lipopolysaccharide (LPS)-induced systemic inflammatory response model and examined underlying mechanisms...
  15. ncbi request reprint Stimulation of autophagy in the liver by lipopolysaccharide-induced systemic inflammation in a rat model of diabetes mellitus
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Oita University, Yufu, Oita, Japan
    Biomed Res 31:263-71. 2010
    ..Thus, autophagy might be related to progression to organ injury in patients with DM, and inflammation in these patients might be associated with over-induction of autophagy and increased HMGB1 expression...
  16. doi request reprint The impact of oxidative stress levels on the clinical effectiveness of sivelestat in treating acute lung injury: an electron spin resonance study
    Shigekiyo Matsumoto
    Department of Anaesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    J Trauma 68:796-801. 2010
    ..Variable baseline levels of oxidative stress in patients with ALI have been proposed as one explanation for inconsistent results...
  17. doi request reprint Antagonist of the type-1 ANG II receptor prevents against LPS-induced septic shock in rats
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka Hasamamachi, Yufu, Oita 879 5593, Japan
    Intensive Care Med 35:1471-8. 2009
    ....
  18. doi request reprint Hydrogen-rich saline solution attenuates renal ischemia-reperfusion injury
    Chihiro Shingu
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasamamachi, Yufu, Oita, 879 5593, Japan
    J Anesth 24:569-74. 2010
    ..A recent study has shown that hydrogen has antioxidant properties. In this study, we tested the hypothesis that a hydrogen-rich saline solution (HRSS) attenuates renal I/R injury in a rodent model...
  19. doi request reprint Uncoupling of peripheral and master clock gene rhythms by reversed feeding leads to an exacerbated inflammatory response after polymicrobial sepsis in mice
    Yoshimasa Oyama
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine and Department of Anesthesiology, Almeida Memorial Hospital, Oita, Japan
    Shock 41:214-21. 2014
    ..Our findings suggest that uncoupling of peripheral and master clock gene rhythms by reversed feeding exacerbates inflammatory responses. ..
  20. pmc Use of perioperative ureteral stent in abdominal aortic aneurysm with retroperitoneal fibrosis - A report of two cases -
    Junya Kusaka
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, Oita, Japan
    Korean J Anesthesiol 63:76-9. 2012
    ..The clinical course of these cases suggests that, in laparotomy with concomitant retroperitoneal fibrosis, preoperative ureteral stent placement can prevent postoperative complications in the renal and urinary systems...
  21. doi request reprint The α-lipoic acid derivative sodium zinc dihydrolipoylhistidinate reduces chemotherapy-induced alopecia in a rat model: a pilot study
    Satoshi Hagiwara
    Department of Anesthesiology and Intensive Care Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Yufu, Oita, 879 5593, Japan
    Surg Today 41:693-7. 2011
    ..In the present study, we evaluated the effects of sodium zinc dihydrolipoylhistidinate (DHLHZn), a new derivative of the multifunctional antioxidant α-lipoic acid, to treat chemotherapy-induced alopecia...
  22. ncbi request reprint [Blood glucose control during cardiac surgery]
    Hironori Koga
    Department of Anesthesiology and Intensive Care Medicine, Fuculty of Medicine, Oita University, Yufu 879 5593
    Masui 58:298-307. 2009
    ....
  23. doi request reprint New lipoic acid derivative drug sodium zinc dihydrolipoylhistidinate prevents cardiac dysfunction in an isolated perfused rat heart model
    Satoshi Hagiwara
    Department of Anesthesiology, Oita University Faculty of Medicine, Oita, Japan
    Crit Care Med 39:506-11. 2011
    ..The purpose of the present study was to determine the cardioprotective effects of the new lipoic acid-derivative drug sodium zinc dihydrolipoylhistidinate in a global ischemia isolated perfused rat heart model...
  24. doi request reprint Effects of hyperglycemia and insulin therapy on high mobility group box 1 in endotoxin-induced acute lung injury in a rat model
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, Oita, Japan
    Crit Care Med 36:2407-13. 2008
    ....