Naoki Kawai

Summary

Affiliation: Nomura Municipal Hospital
Country: Japan

Publications

  1. doi request reprint Increased symptom severity but unchanged neuraminidase inhibitor effectiveness for A(H1N1)pdm09 in the 2010-2011 season: comparison with the previous season and with seasonal A(H3N2) and B
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, Tokyo, Japan
    Influenza Other Respir Viruses 7:448-55. 2013
  2. doi request reprint Persistence of pandemic influenza H1N1 virus in young patients after oseltamivir therapy in the 2009-2010 season: a comparison with seasonal H1N1 with or without H275Y mutation
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Infect Chemother 18:180-6. 2012
  3. ncbi request reprint A change in the effectiveness of amantadine for the treatment of influenza over the 2003-2004, 2004-2005, and 2005-2006 influenza seasons in Japan
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Infect Chemother 13:314-9. 2007
  4. ncbi request reprint A comparison of the effectiveness of zanamivir and oseltamivir for the treatment of influenza A and B
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, 101 0062 Tokyo, Japan
    J Infect 56:51-7. 2008
  5. ncbi request reprint Longer virus shedding in influenza B than in influenza A among outpatients treated with oseltamivir
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, Kanda Surugadai, Chiyoda ku, Tokyo, Japan
    J Infect 55:267-72. 2007
  6. doi request reprint Comparison of the clinical symptoms and the effectiveness of neuraminidase inhibitors for patients with pandemic influenza H1N1 2009 or seasonal H1N1 influenza in the 2007-2008 and 2008-2009 seasons
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Infect Chemother 17:375-81. 2011
  7. doi request reprint Clinical effectiveness of oseltamivir for influenza A(H1N1) virus with H274Y neuraminidase mutation
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Infect 59:207-12. 2009
  8. ncbi request reprint A comparison of the effectiveness of oseltamivir for the treatment of influenza A and influenza B: a Japanese multicenter study of the 2003-2004 and 2004-2005 influenza seasons
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 43:439-44. 2006
  9. ncbi request reprint Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: a multicenter study from Japan of the 2002-2003 influenza season
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 40:1309-16. 2005
  10. ncbi request reprint A prospective, Internet-based study of the effectiveness and safety of influenza vaccination in the 2001-2002 influenza season
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku 101 0062, Tokyo, Japan
    Vaccine 21:4507-13. 2003

Detail Information

Publications22

  1. doi request reprint Increased symptom severity but unchanged neuraminidase inhibitor effectiveness for A(H1N1)pdm09 in the 2010-2011 season: comparison with the previous season and with seasonal A(H3N2) and B
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, Tokyo, Japan
    Influenza Other Respir Viruses 7:448-55. 2013
    ....
  2. doi request reprint Persistence of pandemic influenza H1N1 virus in young patients after oseltamivir therapy in the 2009-2010 season: a comparison with seasonal H1N1 with or without H275Y mutation
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Infect Chemother 18:180-6. 2012
    ....
  3. ncbi request reprint A change in the effectiveness of amantadine for the treatment of influenza over the 2003-2004, 2004-2005, and 2005-2006 influenza seasons in Japan
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Infect Chemother 13:314-9. 2007
    ..In conclusion, the effectiveness of oseltamivir did not change, but the effectiveness of amantadine was progressively reduced over the three influenza seasons...
  4. ncbi request reprint A comparison of the effectiveness of zanamivir and oseltamivir for the treatment of influenza A and B
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, 101 0062 Tokyo, Japan
    J Infect 56:51-7. 2008
    ..To compare the effectiveness of zanamivir with oseltamivir for influenza A and B...
  5. ncbi request reprint Longer virus shedding in influenza B than in influenza A among outpatients treated with oseltamivir
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, Kanda Surugadai, Chiyoda ku, Tokyo, Japan
    J Infect 55:267-72. 2007
    ..To compare the persistence, susceptibility and resistance of influenza A and influenza B viruses in oseltamivir therapy in outpatients of various ages...
  6. doi request reprint Comparison of the clinical symptoms and the effectiveness of neuraminidase inhibitors for patients with pandemic influenza H1N1 2009 or seasonal H1N1 influenza in the 2007-2008 and 2008-2009 seasons
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Infect Chemother 17:375-81. 2011
    ..9-31.5 h). Clinical symptoms were the same or somewhat milder, and oseltamivir was more effective, for pandemic 2009 than for seasonal H1N1 influenza with or without H275Y mutation...
  7. doi request reprint Clinical effectiveness of oseltamivir for influenza A(H1N1) virus with H274Y neuraminidase mutation
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Infect 59:207-12. 2009
    ..To evaluate the clinical effectiveness of oseltamivir therapy started within 48h of the onset for influenza A(H1N1) virus with H274Y neuraminidase (NA) mutation...
  8. ncbi request reprint A comparison of the effectiveness of oseltamivir for the treatment of influenza A and influenza B: a Japanese multicenter study of the 2003-2004 and 2004-2005 influenza seasons
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 43:439-44. 2006
    ..The study included 3351 patients in whom influenza had been diagnosed by use of an antigen detection test kit...
  9. ncbi request reprint Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: a multicenter study from Japan of the 2002-2003 influenza season
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 40:1309-16. 2005
    ....
  10. ncbi request reprint A prospective, Internet-based study of the effectiveness and safety of influenza vaccination in the 2001-2002 influenza season
    Naoki Kawai
    Japan Physicians Association, Tokyo Medical Association Building 3F, 2 5 Kanda Surugadai, Chiyoda ku 101 0062, Tokyo, Japan
    Vaccine 21:4507-13. 2003
    ..These results suggest that influenza vaccination is effective for children and adults and that a two-dose regimen is superior to a single dose in children 0-15 years...
  11. doi request reprint Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons
    Naoki Kawai
    Japan Physicians Association, Tokyo, Japan
    Clin Infect Dis 49:1828-35. 2009
    ..Influenza A virus subtype H1N1 with the H274Y mutation emerged and spread worldwide. However, the clinical effectiveness of the neuraminidase inhibitors, oseltamivir and zanamivir, has not been adequately reevaluated...
  12. doi request reprint In vitro neuraminidase inhibitory concentration (IC50) of four neuraminidase inhibitors against clinical isolates of the influenza viruses circulating in the 2010-2011 to 2014-2015 Japanese influenza seasons
    Hideyuki Ikematsu
    Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 22:599-604. 2016
    ..These results show change in the geometric mean IC50 by season but with no trend, which indicates that the influence of viral mutation on the effectiveness of these NAIs was minute for A(H3N2) and B over the past five seasons. ..
  13. doi request reprint Duration of fever and other symptoms after the inhalation of laninamivir octanoate hydrate for influenza treatment; comparison among the four Japanese influenza seasons from 2011-2012 to 2014-2015
    Hideyuki Ikematsu
    Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 22:605-10. 2016
    ..It is unlikely that the clinical use of laninamivir has caused viral resistance in the currently epidemic viruses. ..
  14. doi request reprint Clinical outcome of laninamivir octanoate hydrate for influenza in the 2013-2014 Japanese season
    Hideyuki Ikematsu
    Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 21:802-7. 2015
    ....
  15. ncbi request reprint Continued effectiveness of laninamivir octanate hydrate for influenza treatment in Japan: comparison between the 2011-2012 and 2012-2013 influenza seasons
    Hideyuki Ikematsu
    Japan Physicians Association, Chiyoda ku, Tokyo 100 0003, Japan
    J Infect Chemother 20:799-803. 2014
    ..87%), but neither was serious. These results suggest that laninamivir continued to be effective against influenza A(H3N2) with no safety issues and that it is unlikely that the clinical use of laninamivir will lead to virus resistance...
  16. doi request reprint In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against clinical isolates of the influenza virus circulating in the Japanese 2013-2014 season
    Hideyuki Ikematsu
    Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 21:634-8. 2015
    ....
  17. doi request reprint In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against clinical isolates of influenza virus in the Japanese 2012-2013 season
    Hideyuki Ikematsu
    Japan Physicians Association, Tokyo, Japan Electronic address
    J Infect Chemother 21:39-42. 2015
    ..No isolate showed an increased IC50 value for A(H1N1)pdm09. These results indicate that the currently epidemic influenza viruses are susceptible to all four neuraminidase inhibitors, with no trend for IC50 values to increase at present...
  18. ncbi request reprint [Clinical symptoms of influenza infection in the 2002-2003 season]
    Naoki Kawai
    Japan Physicians Association
    Kansenshogaku Zasshi 78:681-9. 2004
    ..In addition, the use of a rapid diagnosis kit seems necessary for the diagnosis of influenza in elderly patients, who may have no specific symptoms of influenza...
  19. ncbi request reprint Prevalence of influenza B during the 2004-2005 season in Japan
    Naoki Kawai
    Clin Infect Dis 43:1226-8. 2006
  20. ncbi request reprint Zanamivir treatment is equally effective for both influenza A and influenza B
    Naoki Kawai
    Clin Infect Dis 44:1666. 2007
  21. ncbi request reprint [An analysis of the 2002-2003 influenza epidemic focusing on patients infected with types A and B in the same season sequentially]
    Naoki Kawai
    Department of Clinical Research, Hara Doi Hospital
    Kansenshogaku Zasshi 78:120-8. 2004
    ..001) and type B (p < 0.05). In epidemics consisting of multiple types of influenza viruses, patients may be infected by more than one virus. This is especially true for children...
  22. ncbi request reprint [Effectiveness of oseltamivir on influenza and influencing factors: age of patients, type of influenza virus and timing of initial administration]
    Naoki Kawai
    National Kyushu Medical Center
    Kansenshogaku Zasshi 77:423-9. 2003
    ..Oseltamivir was more effective when administered as early as possible after the onset of the symptoms of influenza...