Tomohiro Kaneko

Summary

Affiliation: Nippon Medical School
Country: Japan

Publications

  1. doi request reprint Comparison of immunosuppressive therapies for IgA nephropathy after tonsillectomy: three-course versus one-course steroid pulse combined with mizoribine
    Tomohiro Kaneko
    Division of Nephrology, Department of Internal Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Int Urol Nephrol 47:1823-30. 2015
  2. ncbi request reprint Efficacy of steroid pulse therapy in combination with mizoribine following tonsillectomy for immunoglobulin A nephropathy in renally impaired patients
    Tomohiro Kaneko
    Divisions of Nephrology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    J Nippon Med Sch 80:279-86. 2013
  3. pmc Methylprednisolone pulse therapy combined with mizoribine following tonsillectomy for immunoglobulin A nephropathy: clinical remission rate, steroid sparing effect, and maintenance of renal function
    Tomohiro Kaneko
    Division of Neurology, Department of Internal Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Clin Exp Nephrol 15:73-8. 2011
  4. doi request reprint Renal thrombotic microangiopathy associated with chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    Akiko Mii
    Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
    Pathol Int 61:518-27. 2011
  5. doi request reprint Role of matrix metalloproteinase-2 in recovery after tubular damage in acute kidney injury in mice
    Tomohiro Kaneko
    Division of Neurology, Nephrology and Rheumatology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Nephron Exp Nephrol 122:23-35. 2012
  6. doi request reprint A case of monoclonal immunoglobulin G1-lambda deposition associated with membranous feature in a patient with hepatitis C viral infection
    Takehisa Yamada
    Division of Neurology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Clin Exp Nephrol 16:468-72. 2012
  7. doi request reprint Development of lymphatic vasculature and morphological characterization in rat kidney
    Maki Tanabe
    Department of Analytic Human Pathology, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8602, Japan
    Clin Exp Nephrol 16:833-42. 2012
  8. pmc Acute graft-versus-host disease of the kidney in allogeneic rat bone marrow transplantation
    Seiichiro Higo
    Department of Nephrology, Nippon Medical School, Tokyo, Japan Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
    PLoS ONE 9:e115399. 2014
  9. ncbi request reprint A patient with idiopathic cholesterol crystal embolization: effectiveness of early detection and treatment
    Seiichiro Higo
    Department of Neurological, Nephrological and Rheumatological Science, Graduate School of Medicine, Nippon Medical School, Japan
    J Nippon Med Sch 78:252-6. 2011
  10. pmc Glomerular endothelial cell injury and focal segmental glomerulosclerosis lesion in idiopathic membranous nephropathy
    Megumi Morita
    Department of Nephrology, Nippon Medical School, Tokyo, Japan
    PLoS ONE 10:e0116700. 2015

Collaborators

  • Akira Shimizu
  • Yasuhiko Iino
  • Kouichi Utsumi
  • Go Kanzaki
  • Tetsuya Kashiwagi
  • Kenji Tajika
  • Shigeru Sato
  • Akiko Mii
  • Yukinari Masuda
  • Yasuo Katayama
  • Seiichiro Higo
  • Yuh Fukuda
  • Emiko Fujita
  • Megumi Morita
  • Shuichi Tsuruoka
  • Kiyotaka Nagahama
  • Kae Ueda
  • Taiko Kusano
  • Keiko Hara
  • Takashi Tani
  • Chikara Ishihara
  • Shinya Nagasaka
  • Yusuke Kajimoto
  • Megumi Fukui
  • Maki Tanabe
  • Takehisa Yamada
  • Xuanyi Du
  • Mitue Kataoka
  • Takashi Arai
  • Kyoko Wakamatsu
  • Arimi Ishikawa
  • Teppei Fujino
  • Ryuji Ohashi
  • Hideki Takano
  • Michiko Aoki
  • Dedong Kang
  • Jun Shoji
  • Syuichi Tsuruoka
  • Fumihiko Yasuda
  • Yuichiro Kishi
  • Toshio Akimoto
  • Yusuke Arakawa
  • Naomi Kuwahara
  • Hiroshi Kawachi
  • Masaaki Uchiyama
  • Akio Hirama
  • Shin ichi Tsuchiya
  • Hiroki Yamaguchi
  • Masamichi Ishizaki
  • Syouichirou Kijima
  • Tosiya Katumata
  • Mineo Ymazaki
  • Sabine Kyoko Saito
  • Yuko Tsuzuku
  • Daisuke Takada
  • Miho Hayashi
  • Seiichi Matsunobu
  • Mituyoshi Shimizu

Detail Information

Publications22

  1. doi request reprint Comparison of immunosuppressive therapies for IgA nephropathy after tonsillectomy: three-course versus one-course steroid pulse combined with mizoribine
    Tomohiro Kaneko
    Division of Nephrology, Department of Internal Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Int Urol Nephrol 47:1823-30. 2015
    ..In this study, we performed tonsillectomy in patients with IgA nephropathy and conducted a comparative study about subsequent immunosuppressive therapy...
  2. ncbi request reprint Efficacy of steroid pulse therapy in combination with mizoribine following tonsillectomy for immunoglobulin A nephropathy in renally impaired patients
    Tomohiro Kaneko
    Divisions of Nephrology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    J Nippon Med Sch 80:279-86. 2013
    ....
  3. pmc Methylprednisolone pulse therapy combined with mizoribine following tonsillectomy for immunoglobulin A nephropathy: clinical remission rate, steroid sparing effect, and maintenance of renal function
    Tomohiro Kaneko
    Division of Neurology, Department of Internal Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Clin Exp Nephrol 15:73-8. 2011
    ..To reduce the total dose of steroids, we have been using mizoribine (MZR) in combination with tonsillectomy-steroid pulse therapy since 2004. Here we report a retrospective evaluation of our protocol outcome...
  4. doi request reprint Renal thrombotic microangiopathy associated with chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    Akiko Mii
    Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
    Pathol Int 61:518-27. 2011
    ..In conclusion, the kidney is a potential target of chronic GVHD that may induce the development of HSCT-associated TMA. Importantly, some cases are associated with chronic humoral GVHD...
  5. doi request reprint Role of matrix metalloproteinase-2 in recovery after tubular damage in acute kidney injury in mice
    Tomohiro Kaneko
    Division of Neurology, Nephrology and Rheumatology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Nephron Exp Nephrol 122:23-35. 2012
    ..In the present study, we analyzed the role of MMP-2 in the repair process in ischemic AKI...
  6. doi request reprint A case of monoclonal immunoglobulin G1-lambda deposition associated with membranous feature in a patient with hepatitis C viral infection
    Takehisa Yamada
    Division of Neurology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Clin Exp Nephrol 16:468-72. 2012
    ..Monoclonal immunoglobulin deposition disease with membranous feature is rare. Additional reports of such cases are needed to elucidate the mechanisms and optimal therapy for this rare entity...
  7. doi request reprint Development of lymphatic vasculature and morphological characterization in rat kidney
    Maki Tanabe
    Department of Analytic Human Pathology, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8602, Japan
    Clin Exp Nephrol 16:833-42. 2012
    ..The mechanisms and morphological characteristics of lymphatic vascular development in embryonic kidneys remain uncertain...
  8. pmc Acute graft-versus-host disease of the kidney in allogeneic rat bone marrow transplantation
    Seiichiro Higo
    Department of Nephrology, Nippon Medical School, Tokyo, Japan Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
    PLoS ONE 9:e115399. 2014
    ..In conclusion, the kidney was a primary target organ of acute GVHD after BMT. Acute GVHD of the kidney was characterized by increased levels of urinary NAG and cell-mediated injury to the renal microvasculature and renal tubules...
  9. ncbi request reprint A patient with idiopathic cholesterol crystal embolization: effectiveness of early detection and treatment
    Seiichiro Higo
    Department of Neurological, Nephrological and Rheumatological Science, Graduate School of Medicine, Nippon Medical School, Japan
    J Nippon Med Sch 78:252-6. 2011
    ..Early diagnosis and treatment are important. Renal dysfunction is a common symptom in elderly patients. Cholesterol crystal embolization should also be considered as a cause of unexplained renal dysfunction, especially in such patients...
  10. pmc Glomerular endothelial cell injury and focal segmental glomerulosclerosis lesion in idiopathic membranous nephropathy
    Megumi Morita
    Department of Nephrology, Nippon Medical School, Tokyo, Japan
    PLoS ONE 10:e0116700. 2015
    ..Focal segmental glomerulosclerosis (FSGS) lesions have often been discussed as a negative predictor in idopathic membranous nephropathy (MN). The mechanism of the development of FSGS lesion in MN is still uncertain...
  11. ncbi request reprint [Two cases of rapidly progressive nephritic syndrome complicated with alcoholic liver cirrhosis]
    Tomohiro Kaneko
    Divisions of Neurology, Nippon Medical School, Tokyo, Japan
    Nihon Jinzo Gakkai Shi 53:60-7. 2011
    ..Active use of immune system suppressor therapy was effective...
  12. doi request reprint Proliferative glomerulonephritis with monoclonal immunoglobulin G3κ deposits in association with parvovirus B19 infection
    Emiko Fujita
    Department of Internal Medicine Division of Neurology, Nephrology, and Rheumatology, Nippon Medical School, Tokyo 113 8602, Japan
    Hum Pathol 43:2326-33. 2012
    ..Virus infection-associated immune disorders could be implicated in the pathogenesis of proliferative glomerulonephritis with monoclonal immunoglobulin G deposits...
  13. doi request reprint A case of lupus nephritis with diffuse podocytic infolding into the glomerular basement membrane
    Akiko Mii
    Department of Analytic Human Pathology, Nippon Medical School, 1 15 Sendagi, Bunkyo ku, Tokyo, 113 8602, Japan
    Clin Exp Nephrol 12:479-84. 2008
    ..After a renal biopsy, the patient received oral prednisolone 0.8 mg/kg day initially, and her complete remission status continued for 5 years...
  14. doi request reprint Renal thrombotic microangiopathy associated with chronic humoral graft versus host disease after hematopoietic stem cell transplantation
    Akiko Mii
    Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
    Pathol Int 61:34-41. 2011
    ..Furthermore, C4d deposition suggests complement activation. Although circulating anti-blood type and anti-human leukocyte antigen antibodies were not detected, the renal TMA in this case was probably associated with chronic humoral GVHD...
  15. doi request reprint Endothelial cell injury in acute and chronic glomerular lesions in patients with IgA nephropathy
    Taiko Kusano
    Department of Analytic Human Pathology, Nippon Medical School, Tokyo, 113 8602, Japan Division of Nephrology, Tokyo Teishin Hospital, Tokyo, 102 8798, Japan
    Hum Pathol 49:135-44. 2016
    ..In conclusion, injuries of glomerular capillaries and the loss of endothelial cells occurred in the acute and chronic glomerular lesions in IgAN and may contribute to the development of hematuria, proteinuria, and renal dysfunction. ..
  16. doi request reprint IgA nephropathy and psoriatic arthritis that improved with steroid pulse therapy and mizoribine in combination with treatment for chronic tonsillitis and epipharyngitis
    Tomohiro Kaneko
    Division of Nephrology, Department of Internal Medicine, Nippon Medical School, Japan
    Intern Med 54:1085-90. 2015
    ..In this case, adding treatment for chronic epipharyngitis accelerated the curative effects, and focal infection therapy consisting of immunosuppressive drugs was effective for both IgAN and psoriatic arthritis. ..
  17. doi request reprint Involvement of matrix metalloproteinase-2 in the development of renal interstitial fibrosis in mouse obstructive nephropathy
    Xuanyi Du
    Department of Pathology Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
    Lab Invest 92:1149-60. 2012
    ..The results suggested that MMP-2 have a pathogenic role in renal interstitial fibrosis, possibly through the induction of EMT and macrophage infiltration. Inhibition of MMPs may be beneficial therapeutically in renal fibrosis...
  18. ncbi request reprint Severe thiamine deficiency resulted in Wernicke's encephalopathy in a chronic dialysis patient
    Kae Ueda
    Second Department of Internal Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Clin Exp Nephrol 10:290-3. 2006
    ..Wernicke's encephalopathy should be considered as one of many causes of disturbed consciousness in hemodialysis patients. A rapid diagnosis and adequate treatment are essential in order to minimize long-term neurological sequelae...
  19. doi request reprint Focal segmental glomerulosclerosis after renal transplantation
    Akira Shimizu
    Department of Pathology Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
    Clin Transplant 25:6-14. 2011
    ..The pathological diagnosis of FSGS is based on the 2004 Columbia classification system. In the present minireview, we discuss the pathology of recurrence and de novo FSGS after kidney transplantation...
  20. ncbi request reprint [A successful treatment of HELLP syndrome associated with RPLS by early plasma exchange]
    Keiko Hara
    Division of Neurology, Department of Internal Medicine, Nippon Medical School, Tokyo
    Nihon Naika Gakkai Zasshi 96:983-5. 2007
  21. doi request reprint Multiple cerebral lesions as the unique complication of idiopathic retroperitoneal fibrosis
    Takashi Tani
    Department of Nephrology, Nippon Medical School, Tokyo, Japan
    Mod Rheumatol 25:468-71. 2015
    ..Details on this case manifesting rare cerebrovascular complications may help elucidate the pathogenesis of IRF. ..
  22. ncbi request reprint [Multiple myeloma light chain deposition with specific pathological change]
    Yuichiro Kishi
    Second Department of Internal Medicine, Nippon Medical School, Tokyo
    Nihon Naika Gakkai Zasshi 91:749-51. 2002