Ken Nagao

Summary

Affiliation: Nihon University
Country: Japan

Publications

  1. ncbi request reprint Resuscitative value of B-type natriuretic peptide in comatose survivors treated with hypothermia after out-of-hospital cardiac arrest due to cardiac causes
    Ken Nagao
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:370-6. 2007
  2. ncbi request reprint Safety and efficacy of sirolimus-eluting stent in patients with acute coronary syndrome undergoing emergency procedure
    Kazumiki Nomoto
    Department of Cardiology, Kawaguchi Municipal Medical Center, 180 Nishi araijuku, Kawaguchi 333 0833, Japan
    Circ J 72:1054-8. 2008
  3. ncbi request reprint Early induction of hypothermia during cardiac arrest improves neurological outcomes in patients with out-of-hospital cardiac arrest who undergo emergency cardiopulmonary bypass and percutaneous coronary intervention
    Ken Nagao
    Department of Cardiology, Resuscitation and Emergency Cardiovascular Care, Surugadai Nihon University Hospital, Japan
    Circ J 74:77-85. 2010
  4. doi request reprint Chest compression-only cardiocerebral resuscitation
    Ken Nagao
    Department of Cardiology, Resuscitation and Emergency Cardiovascular Care, Surugadai Nihon University Hospital 1 8 13, Nihon University School of Medicine, Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Curr Opin Crit Care 15:189-97. 2009
  5. ncbi request reprint B-type natriuretic peptide as a marker of resuscitation in patients with cardiac arrest outside the hospital
    Ken Nagao
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 68:477-82. 2004
  6. ncbi request reprint Diagnostic value of adenosine-induced left ventricular diastolic dysfunction for detecting coronary artery restenosis in patients undergoing stent implantation by Stress ECG-gated myocardial perfusion SPECT. A pilot study
    Yoshimochi Nakano
    Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 74:2658-65. 2010
  7. doi request reprint Development of a model for prediction of coronary atherosclerotic regression: evaluation of high-density lipoprotein cholesterol level and peripheral blood monocyte count
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Heart Vessels 27:143-50. 2012
  8. doi request reprint Treatment of coronary spastic angina with a statin in addition to a calcium channel blocker: a pilot study
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    J Cardiovasc Pharmacol 52:28-34. 2008
  9. ncbi request reprint Increasingly well-preserved left ventricular function in hospital survivors with acute myocardial infarction: effect of early and complete reperfusion strategy on left ventricular remodeling
    Shigemasa Tani
    Division of Cardiovascular Medicine, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:180-5. 2007
  10. doi request reprint Association of leukocyte subtype counts with coronary atherosclerotic regression following pravastatin treatment
    Shigemasa Tani
    Department of Cardiology, Nihon University, Surugadai Hospital, Tokyo, Japan
    Am J Cardiol 104:464-9. 2009

Detail Information

Publications79

  1. ncbi request reprint Resuscitative value of B-type natriuretic peptide in comatose survivors treated with hypothermia after out-of-hospital cardiac arrest due to cardiac causes
    Ken Nagao
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:370-6. 2007
    ....
  2. ncbi request reprint Safety and efficacy of sirolimus-eluting stent in patients with acute coronary syndrome undergoing emergency procedure
    Kazumiki Nomoto
    Department of Cardiology, Kawaguchi Municipal Medical Center, 180 Nishi araijuku, Kawaguchi 333 0833, Japan
    Circ J 72:1054-8. 2008
    ..This study investigated the safety and efficacy of SES for emergency PCI in acute coronary syndrome (ACS) patients...
  3. ncbi request reprint Early induction of hypothermia during cardiac arrest improves neurological outcomes in patients with out-of-hospital cardiac arrest who undergo emergency cardiopulmonary bypass and percutaneous coronary intervention
    Ken Nagao
    Department of Cardiology, Resuscitation and Emergency Cardiovascular Care, Surugadai Nihon University Hospital, Japan
    Circ J 74:77-85. 2010
    ..Therapeutic hypothermia for comatose survivors of out-of-hospital cardiac arrest has demonstrated neurological benefits. Although early cooling during cardiac arrest enhances efficacy in animal studies, few clinical studies are available...
  4. doi request reprint Chest compression-only cardiocerebral resuscitation
    Ken Nagao
    Department of Cardiology, Resuscitation and Emergency Cardiovascular Care, Surugadai Nihon University Hospital 1 8 13, Nihon University School of Medicine, Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Curr Opin Crit Care 15:189-97. 2009
    ..I review the efficacy of chest compression-only cardiocerebral resuscitation (CCR) for all adult patients with out-of-hospital cardiac arrest...
  5. ncbi request reprint B-type natriuretic peptide as a marker of resuscitation in patients with cardiac arrest outside the hospital
    Ken Nagao
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 68:477-82. 2004
    ..Although the circulating concentration of B-type natriuretic peptide (BNP) has both a prognostic and diagnostic value in heart disease, no data are available regarding its resuscitative value for out-of-hospital cardiac arrest...
  6. ncbi request reprint Diagnostic value of adenosine-induced left ventricular diastolic dysfunction for detecting coronary artery restenosis in patients undergoing stent implantation by Stress ECG-gated myocardial perfusion SPECT. A pilot study
    Yoshimochi Nakano
    Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 74:2658-65. 2010
    ....
  7. doi request reprint Development of a model for prediction of coronary atherosclerotic regression: evaluation of high-density lipoprotein cholesterol level and peripheral blood monocyte count
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Heart Vessels 27:143-50. 2012
    ..6% showed the increase of the plaque volume (2.6%). In view of the inflammatory nature of atherosclerosis, the model constructed using the two predictors may be a useful model for the prediction of plaque regression...
  8. doi request reprint Treatment of coronary spastic angina with a statin in addition to a calcium channel blocker: a pilot study
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    J Cardiovasc Pharmacol 52:28-34. 2008
    ..The results showed that improvement of lipid metabolism, especially an increase of HDL cholesterol level and a reduction of MDA-LDL, may inhibit vascular contractility...
  9. ncbi request reprint Increasingly well-preserved left ventricular function in hospital survivors with acute myocardial infarction: effect of early and complete reperfusion strategy on left ventricular remodeling
    Shigemasa Tani
    Division of Cardiovascular Medicine, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:180-5. 2007
    ..Progress in reperfusion therapy for acute myocardial infarction (AMI) has greatly reduced acute phase mortality, but few data exist regarding the time trends in left ventricular (LV) remodeling in hospital survivors of AMI...
  10. doi request reprint Association of leukocyte subtype counts with coronary atherosclerotic regression following pravastatin treatment
    Shigemasa Tani
    Department of Cardiology, Nihon University, Surugadai Hospital, Tokyo, Japan
    Am J Cardiol 104:464-9. 2009
    ..In conclusion, the decrease in monocyte count as a nonlipid-lowering effect of statins may be used as a novel marker of coronary atherosclerotic regression...
  11. ncbi request reprint Prognostic value of venous blood ammonia in patients with out-of-hospital cardiac arrest
    Asuka Kasai
    Department of Emergency Care, Surugadai Nihon University Hospital, Surugadai Nihon University Hospital, Tokyo, Japan
    Circ J 76:891-9. 2012
    ..Although studies have shown there is a correlation between increased blood ammonia level and hepatic encephalopathy, little information is available for patients with out-of-hospital cardiac arrest...
  12. ncbi request reprint Low-density lipoprotein cholesterol/apolipoprotein B ratio may be a useful index that differs in statin-treated patients with and without coronary artery disease: a case control study
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Int Heart J 52:343-7. 2011
    ..Such monitoring is particularly important in patients with elevated serum TG levels, which is associated with smaller sizes of LDL-particles...
  13. doi request reprint Relation of change in apolipoprotein B/apolipoprotein A-I ratio to coronary plaque regression after Pravastatin treatment in patients with coronary artery disease
    Shigemasa Tani
    Department of Cardiology, Nihon University, Surugadai Hospital, Tokyo, Japan
    Am J Cardiol 105:144-8. 2010
    ..0023). In conclusion, our results have indicated that the decrease in the apoB/apoA-I ratio is a simple predictor for coronary atherosclerotic regression: the lower the apoB/apoA-I ratio, the lower the risk of coronary atherosclerosis...
  14. ncbi request reprint Coronary plaque regression and lifestyle modification in patients treated with pravastatin. - Assessment mainly by daily aerobic exercise and an increase in the serum level of high-density lipoprotein cholesterol -
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Circ J 74:954-61. 2010
    ..The purpose of this study was to explore the effect of lifestyle modification, mainly daily aerobic exercise, on coronary atherosclerosis in patients with coronary artery disease (CAD)...
  15. ncbi request reprint Combined assessment of myocardial perfusion and function by ECG-gated myocardial perfusion single-photon emission computed tomography for the prediction of future cardiac events in patients with type 2 diabetes mellitus
    Masahiko Kato
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 75:376-82. 2011
    ..In the present study rates of future cardiac events (nonfatal acute myocardial infarction (AMI), cardiac death (CD) and severe heart failure (HF) requiring hospitalization) were compared in patients with and without DM...
  16. ncbi request reprint Pure ventricular septal myocardial infarction in a young man with coronary artery ectasia
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Int Heart J 47:131-7. 2006
    ....
  17. ncbi request reprint Effect of pravastatin on malondialdehyde-modified low-density lipoprotein levels and coronary plaque regression as determined by three-dimensional intravascular ultrasound
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Am J Cardiol 96:1089-94. 2005
    ..In conclusion, these results suggest that the reduction in the MDA-LDL levels induced by pravastatin may serve as a novel marker of coronary atherosclerosis regression...
  18. ncbi request reprint Association of body mass index with coronary plaque regression: 6-month prospective study
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo 101 8309, Japan
    J Atheroscler Thromb 16:275-82. 2009
    ..Obesity is a well known strong risk factor for coronary artery disease (CAD). We prospectively investigated the influence of body mass index (BMI) on the inhibitory effects of pravastatin against the development of coronary atherosclerosis...
  19. ncbi request reprint Effects of enalapril and losartan in left ventricular remodeling after acute myocardial infarction: a possible mechanism of prevention of cardiac events by angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in high-risk myocardial
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo
    Intern Med 48:877-82. 2009
    ..However, there are few data on the effects of these drugs on left-ventricular (LV) remodeling after MI in Japanese patients...
  20. ncbi request reprint Predictive factors of TIMI-3 flow before percutaneous coronary intervention in facilitated percutaneous coronary intervention for acute myocardial infarction
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, Tokyo, Japan
    Int Heart J 47:29-35. 2006
    ..The WBC count and hemoglobin value on arrival at the emergency room and history of smoking were shown to be independent factors for acquisition of TIMI-3 flow before PCI in facilitated PCI...
  21. doi request reprint Association of circulating leukocyte count with coronary atherosclerosis regression after pravastatin treatment
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Atherosclerosis 198:360-5. 2008
    ..In conclusion, a reduction of the leukocyte count as one of the non-lipid-lowering effects of pravastatin may be a novel marker of regression of coronary atherosclerosis...
  22. ncbi request reprint Relationship between the door-to-TIMI-3 flow time and the infarct size in patients suffering from acute myocardial infarction: analysis based on the fibrinolysis and subsequent transluminal (FAST-3) trial
    Kazuhiro Watanabe
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    Circ J 68:280-5. 2004
    ....
  23. ncbi request reprint Reperfusion strategy for acute myocardial infarction in elderly patients aged 75 to 80 years
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, 1 8 13 Kandasurugadai, Tokyo 101 0062, Japan
    Heart Vessels 21:236-41. 2006
    ..Considering reperfusion therapy in elderly patients with acute myocardial infarction, we concluded that facilitated PCI may be effective in elderly patients aged 75-80 years...
  24. ncbi request reprint Unexpected coronary vasospasm of a contralateral artery during balloon angioplasty
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital, 1 8 13 Kandasurugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Heart Vessels 20:82-4. 2005
    ..We experienced a rare case of shock with vasospasm of the right coronary artery in a patient following balloon angioplasty performed for stent restenosis of the left anterior descending artery...
  25. doi request reprint Changes of cerebral oxygen metabolism and hemodynamics during ECPR with hypothermia measured by near-infrared spectroscopy: a pilot study
    Tsukasa Yagi
    Department of Cardiology, Cardiopulmonary Resuscitation and Emergency Cardiovascular Care, Surugadai Nihon University Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Adv Exp Med Biol 789:121-8. 2013
    ..To clarify this issue, we evaluated changes of cerebral blood oxygenation (CBO) during ECPR using near-infrared spectroscopy (NIRS)...
  26. ncbi request reprint Incremental prognostic value of cardiac function assessed by ECG-gated myocardial perfusion SPECT for the prediction of future acute coronary syndrome
    Naoya Matsumoto
    Department of Cardiology, Nihon University School of Medicine, Tokyo
    Circ J 72:2035-9. 2008
    ....
  27. ncbi request reprint Relationship between plasma homocysteine levels and congestive heart failure in patients with acute myocardial infarction. Homocysteine and congestive heart failure
    Takehiko Washio
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo, Japan
    Int Heart J 52:224-8. 2011
    ..8 µmol/L or higher was a risk factor for the development of heart failure (HR: 7.175, P < 0.01). The plasma homocysteine level in patients with AMI may be related to the development of heart failure...
  28. ncbi request reprint Efficacy of calcium channel blocker in the secondary prevention of myocardial infarction--retrospective analysis of the 10-year prognosis or coronary thrombolysis-treated patients
    Shigemasa Tani
    Division of Cardiology, Department of Internal Medicine, Nihon University School of Medicine and Surugadai Nihon University Hospital, Chiyoda ku, Tokyo, Japan
    Circ J 68:853-9. 2004
    ..Calcium channel blockers (CCBs) may have a positive influence on the long-term prognosis of Japanese patients with ischemic heart disease...
  29. doi request reprint Detection of coronary artery disease by free-breathing, whole heart coronary magnetic resonance angiography: our initial experience
    Taeko Kunimasa
    Department of Integrative Health Medicine, Nihon University School of Medicine, 30 1 Oyaguchi Kamimachi, Itabashi ku, Tokyo 173 8610, Japan
    Heart Vessels 24:429-33. 2009
    ....
  30. doi request reprint Does Antiarrhythmic Drug During Cardiopulmonary Resuscitation Improve the One-month Survival: The SOS-KANTO 2012 Study
    Mari Amino
    Tokai University School of Medicine, Kanagawa, Japan Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, Japan Saitama Red Cross Hospital, Saitama, Japan Nihon University Surugadai Hospital, Tokyo, Japan Nihon University School of Medicine, Tokyo, Japan National Cerebral and Cardiovascular Center Hospital, Osaka, Japan National Center of Neurology and Psychiatry, Tokyo, Japan Tokyo Women s Medical University Hospital, Tokyo, Japan and Yokohama City University Medical Center, Kanagawa, Japan
    J Cardiovasc Pharmacol 68:58-66. 2016
    ..This study retrospectively evaluated the effect of AAD administration during CPR on 1-month prognosis in the SOS-KANTO 2012 study population...
  31. ncbi request reprint Relationship between the generation and the facilitated percutaneous coronary intervention in patients with acute myocardial infarction--analysis based on the fibrinolysis and subsequent transluminal trial--
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, Chiyoda ku, Tokyo, Japan
    Circ J 68:1117-22. 2004
    ..The purpose of the present study was to evaluate the efficacy and safety of facilitated percutaneous coronary intervention (PCI) in comparing young and elderly patients with acute myocardial infarction...
  32. ncbi request reprint Regulation of arginine vasopressin in the human heart
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, Tokyo, Japan
    Circ J 69:1401-4. 2005
    ..The role of arginine vasopressin (AVP) in the heart has yet to be determined. The present study was designed to examine whether AVP is regulated in the human heart...
  33. pmc Association between the docosahexaenoic acid to arachidonic acid ratio and acute coronary syndrome: a multicenter observational study
    Yuji Nishizaki
    Department of Cardiology, Juntendo University Graduate School of Medicine, 2 1 1 Hongo Bunkyo ku, Tokyo, 113 8421, Japan
    BMC Cardiovasc Disord 16:143. 2016
    ..However, the association between the docosahexaenoic acid (DHA) to AA ratio and ACS remains unclear. This study aimed to assess the association between the DHA/AA ratio and ACS by patient characteristics...
  34. doi request reprint Detection of ROSC in Patients with Cardiac Arrest During Chest Compression Using NIRS: A Pilot Study
    Tsukasa Yagi
    Department of Cardiology, Nihon University Hospital, 1 6 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Adv Exp Med Biol 876:151-7. 2016
    ..NIRS appears to be applicable for detection of ROSC without interruption of chest compression and without endotracheal intubation. ..
  35. doi request reprint WITHDRAWN: Mechanical circulatory support with optimal coronary reflow in a cardiogenic shock complicating acute myocardial infarction
    Makoto Suzuki
    Department of Cardiovascular Medicine, Sakakibara Heart Institute, Tokyo, Japan Tokyo CCU Network Scientific Council, Tokyo, Japan Electronic address
    J Cardiol 67:124. 2016
    ..The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ..
  36. ncbi request reprint [Thrombolytic (fibrinolytic) agents for treatment of ischemic heart disease]
    Ken Nagao
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine
    Nihon Rinsho 61:641-6. 2003
  37. doi request reprint Association of cholesteryl ester transfer protein mass with peripheral leukocyte count following statin therapy: a pilot study
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Am J Cardiovasc Drugs 12:349-54. 2012
    ..However, the role of the CETP mass in the development of atherosclerosis is still unclear...
  38. doi request reprint Decreased activated protein C levels as a clinical predictor in patients with ST-elevation myocardial infarction
    Nobutaka Chiba
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, and Surugadai Nihon University Hospital, Tokyo, Japan
    Am Heart J 156:931-8. 2008
    ....
  39. doi request reprint Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β₁ and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats
    Shinsuke Harasawa
    Department of Cardiology, Nihon University Surugadai Hospital Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Pharm Pharmacol 62:1740-5. 2010
    ..We evaluated whether the calcium channel blocker confers cardiac protection through the renin-angiotensin-aldosterone system in male stroke-prone spontaneously hypertensive rats (SHR-SP)...
  40. pmc Nighttime is associated with decreased survival and resuscitation efforts for out-of-hospital cardiac arrests: a prospective observational study
    Yosuke Matsumura
    Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba City, Chiba, 260 8677, Japan
    Crit Care 20:141. 2016
    ..Whether temporal differences alter the clinical outcomes of patients with out-of-hospital cardiac arrest (OHCA) remains inconclusive. Furthermore, the relationship between time of day and resuscitation efforts is unknown...
  41. doi request reprint Duration of Prehospital Resuscitation Efforts After Out-of-Hospital Cardiac Arrest
    Ken Nagao
    From Cardiovascular Center K N, S F, S T, Nihon University Hospital, Tokyo, Japan Department of Cardiology, Shizuoka General Hospital, Shizuoka, Japan H N Department of Epidemiology and Biostatistics, National Center of Neurology and Psychiatry, Tokyo, Japan N Y Department of Emergency Medicine, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA D F G Department of Cardiology, Kawasaki Saiwai Hospital, Japan N I Department of Cardiology, Sakakibara Heart Institute, Tokyo, Japan M T Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan S S Department of Cardiology, Kyoto University, Japan T K and Department of Cardiology, Fukuoka University of School of Medicine, Japan K S
    Circulation 133:1386-96. 2016
    ..During out-of-hospital cardiac arrest, it is unclear how long prehospital resuscitation efforts should be continued to maximize lives saved...
  42. ncbi request reprint Double left anterior descending artery arising from right and left sinus of Valsalva in patient with acute coronary syndrome
    Michiaki Matsumoto
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Surugadai Kanda Chiyoda ku, Tokyo 101 8309, Japan
    Int J Cardiol 149:e40-2. 2011
    ..We describe here congenital coronary anomaly case which would be misleading as a total occlusion...
  43. ncbi request reprint Non-invasive assessment and clinical strategy of stable coronary artery disease by magnetic resonance imaging, multislice computed tomography and myocardial perfusion SPECT
    Naoya Matsumoto
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Japan
    Circ J 74:34-40. 2010
    ..Circ J 2010; 74: 34 - 40)...
  44. ncbi request reprint Prognostic value of blood glucose in patients with cardiogenic shock
    Katsushige Tada
    Department of Emergency Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 70:1064-9. 2006
    ..Although an elevated blood glucose has prognostic value in cardiovascular disease, few data are available regarding its prognostic value for patients across the spectrum of cardiogenic shock...
  45. pmc Current characteristics and management of ST elevation and non-ST elevation myocardial infarction in the Tokyo metropolitan area: from the Tokyo CCU network registered cohort
    Hideki Miyachi
    Tokyo CCU Network Scientific Committee, Tokyo, Japan
    Heart Vessels 31:1740-1751. 2016
    ....
  46. pmc Applying the termination of resuscitation rules to out-of-hospital cardiac arrests of both cardiac and non-cardiac etiologies: a prospective cohort study
    Masahiro Kashiura
    Tertiary Emergency Medical Center, Tokyo Metropolitan Bokutoh Hospital, 4 23 15 Kotobashi, Sumida ku, 130 8575, Tokyo, Japan
    Crit Care 20:49. 2016
    ..However, it is unclear whether the TOR rules are valid for out-of-hospital cardiac arrests (OHCAs) of both cardiac and non-cardiac etiologies. In this study, we validated the TOR rules for OHCA resulting from both etiologies...
  47. pmc Time Interval from Symptom Onset to Hospital Care in Patients with Acute Heart Failure: A Report from the Tokyo Cardiac Care Unit Network Emergency Medical Service Database
    Yasuyuki Shiraishi
    Tokyo CCU Network Scientific Committee, Tokyo, Japan
    PLoS ONE 10:e0142017. 2015
    ..There seems to be two distinct patterns in the presentation of acute heart failure (AHF) patients; early- vs. gradual-onset. However, whether time-dependent relationship exists in outcomes of patients with AHF remains unclear...
  48. doi request reprint HMG-CoA reductase inhibitor (Statin) therapy and coronary atherosclerosis in Japanese subjects: role of high-density lipoprotein cholesterol
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Am J Cardiovasc Drugs 11:411-7. 2011
    ..We hypothesized that the indicators of coronary plaque regression in response to statin therapy in a Japanese population are different from the indicators in Western populations...
  49. ncbi request reprint Successful recovery using surgical intervention to treat ischemic cardiomyopathy and cardiogenic shock
    Satoshi Unosawa
    Department of Cardiovascular Surgery, Nihon University School of Medicine, 30 1 Ooyaguchi kami machi, Itabashi ku, Tokyo, Japan
    Ann Thorac Cardiovasc Surg 16:52-4. 2010
    ..The LVAD was successfully explanted at the time of simultaneous coronary artery bypass grafting and left ventricular restoration after recovery from end-organ dysfunction by LVAD support...
  50. doi request reprint Association of the serum apolipoprotein levels with the occurrence of coronary vasospasm
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Coron Artery Dis 22:125-30. 2011
    ..The relationship between the serum levels of atherosclerosis-related apolipoprotein (apo) and the risk of coronary spastic angina remains unknown...
  51. doi request reprint Reduced effectiveness of vasopressin in repeated doses for patients undergoing prolonged cardiopulmonary resuscitation
    Takeo Mukoyama
    Department of Acute Medicine, Nihon University School of Medicine, Oyaguchi Kamimachi, Itabashi ku, Tokyo, Japan
    Resuscitation 80:755-61. 2009
    ..This study was conducted to estimate the effectiveness of the repeated administration of vasopressin vs. epinephrine for cardiopulmonary arrest (CPA) patients receiving prolonged CPR...
  52. doi request reprint Usefulness of synthesized 18-lead electrocardiography in the diagnosis of ST-elevation myocardial infarction: A pilot study
    Tadashi Ashida
    Department of Cardiology, Nihon University Hospital, Tokyo, Japan Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Am J Emerg Med . 2016
    ....
  53. doi request reprint Association between urinary albumin excretion and low-density lipoprotein heterogeneity following treatment of type 2 diabetes patients with the dipeptidyl peptidase-4 inhibitor, vildagliptin: a pilot study
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Am J Cardiovasc Drugs 13:443-50. 2013
    ..We evaluated the effects of a DPP-4 inhibitor on atherogenic low-density lipoprotein (LDL) heterogeneity and albuminuria in diabetics as an indicator of the severity of diabetic nephropathy...
  54. ncbi request reprint Takotsubo-shaped cardiomyopathy with type I CD36 deficiency
    Toshio Kushiro
    Department of Cardiology, Nihon University Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Heart Vessels 20:123-5. 2005
    ..Further studies of Takotsubo-shaped cardiomyopathy and CD36 deficiency may reveal an association between this cardiomyopathy and specific genetic profiles...
  55. ncbi request reprint Mismatch between results of myocardial fractional flow reserve (FFR) measurements and myocardial perfusion SPECT for identification of the severity of ischemia: pitfall of FFR in patients with prior myocardial infarction
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo 101 8309, Japan
    Jpn Heart J 45:867-72. 2004
    ..If a FFR cutoff value of 0.75 is applied as in angina patients to patients with myocardial infarction, the severity of ischemia may be underestimated...
  56. ncbi request reprint Efficacy of multislice computed tomography for the detection of acute coronary syndrome in the emergency department
    Yuichi Sato
    Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan
    Circ J 69:1047-51. 2005
    ..Multislice computed tomography (MSCT) allows assessment of not only coronary artery stenoses and occlusions, but also assessment of coronary artery plaques and myocardial perfusion status...
  57. doi request reprint Association of the low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio and body mass index with coronary plaque regression
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Am J Cardiovasc Drugs 12:279-86. 2012
    ..We hypothesized that a reasonable predictive model of coronary plaque regression could be constructed using ΔLDL-C/HDL-C and the body mass index (BMI)...
  58. doi request reprint Predictors for good cerebral performance among adult survivors of out-of-hospital cardiac arrest
    Toshikazu Abe
    Department of Emergency and Critical Care Medicine, St Luke s International Hospital, 9 1 Akashi cho, Chuo City, Tokyo 104 8560, Japan
    Resuscitation 80:431-6. 2009
    ..Complete neurological recovery is of great importance to survivors of cardiac arrest. Few studies have explored predictors of good cerebral performance outcomes among these...
  59. ncbi request reprint [Mutant t-PA compared with native t-PA in acute myocardial infarction]
    Ken Nagao
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine
    Nihon Rinsho 61:453-6. 2003
  60. ncbi request reprint Relationship between heart-type fatty acid-binding protein levels and the risk of death in patients with serious condition on arrival at the emergency department
    Kiyoshi Iida
    Department of Cardiology, Nihon University School of Medicine, Tokyo
    Intern Med 44:1039-45. 2005
    ..The objective of this study is to clarify the prognostic value of H-FABP in patients with a serious condition...
  61. doi request reprint Association of lecithin-cholesterol acyltransferase activity measured as a serum cholesterol esterification rate and low-density lipoprotein heterogeneity with cardiovascular risk: a cross-sectional study
    Shigemasa Tani
    Department of Health Planning Center, Nihon University Hospital, 1 6 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Heart Vessels 31:831-40. 2016
    ....
  62. doi request reprint Contribution of apolipoprotein A-I to the reduction in high-sensitivity C-reactive protein levels by different statins: comparative study of pitavastatin and atorvastatin
    Shigemasa Tani
    Health Planning Center, Nihon University School of Medicine, 1 7 3 Kandasurugadai, Chiyoda ku, Tokyo, 101 0062, Japan
    Heart Vessels 30:762-70. 2015
    ..A decrease in hs-CRP level accompanied by an increase in apoA-I level may be involved in the pleiotropic effects of pitavastatin...
  63. pmc Gender Differences in Patients with Takotsubo Cardiomyopathy: Multi-Center Registry from Tokyo CCU Network
    Tsutomu Murakami
    The Tokyo CCU Network Scientific Committee, Tokyo, Japan
    PLoS ONE 10:e0136655. 2015
    ..The clinical features of gender differences in takotsubo cardiomyopathy (TC) remain to be determined. The aim of this study was to evaluate the differences in clinical characteristics of male and female patients with TC...
  64. doi request reprint Association of triglyceride-rich lipoproteins-related markers and low-density lipoprotein heterogeneity with cardiovascular risk: effectiveness of polyacrylamide-gel electrophoresis as a method of determining low-density lipoprotein particle size
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan Electronic address
    J Cardiol 63:60-8. 2014
    ..We investigated the risk of atherosclerotic cardiovascular disease through examining the relation between triglyceride (TG) metabolism and LDL-heterogeneity as assessed by polyacrylamide-gel electrophoresis (PAGE)...
  65. ncbi request reprint Highly purified eicosapentaenoic acid may increase low-density lipoprotein particle size by improving triglyceride metabolism in patients with hypertriglyceridemia
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital
    Circ J 77:2349-57. 2013
    ....
  66. ncbi request reprint [Intravenous coronary thrombolysis on evidence based reperfusion therapy for acute myocardial infarction]
    Ken Nagao
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine
    Nihon Rinsho 61:446-52. 2003
  67. ncbi request reprint Diffuse pulmonary hemorrhage as a fatal complication of Schönlein-Henoch purpura
    Keiko Usui
    Department of Dermatology, Surugadai Nihon University Hospital, Chiyoda ku, Tokyo, Japan
    J Dermatol 34:705-8. 2007
    ..Although the combination of the corticosteroid and immunosuppressive agents is normally recommended, diffuse pulmonary hemorrhage could become a fatal complication in elderly Schönlein-Henoch patients...
  68. ncbi request reprint Effect of pravastatin on coronary plaque volume
    Kazutoshi Ishikawa
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    Am J Cardiol 92:975-7. 2003
    ..The changes in plaque volume were inversely correlated with the changes in plasma levels of high-density lipoprotein cholesterol but not with changes in levels of total cholesterol or low-density lipoprotein cholesterol...
  69. doi request reprint Effect of Febuxostat, a Xanthine Oxidase Inhibitor, on Cardiovascular Risk in Hyperuricemic Patients with Hypertension: A Prospective, Open-label, Pilot Study
    Shigemasa Tani
    Department of Health Planning Center, Nihon University Hospital, 1 6 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Clin Drug Investig 35:823-31. 2015
    ..We hypothesized that febuxostat, a xanthine oxidase inhibitor, may be associated with suppressing the renin-angiotensin-aldosterone system (RAAS) and improving renal function in hyperurecemic patients with hypertension...
  70. doi request reprint Association of atherosclerosis-related markers and its relationship to n-3 polyunsaturated fatty acids levels with a prevalence of coronary artery disease in an urban area in Japan
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Heart Vessels 30:9-19. 2015
    ..This cross-sectional study suggests that higher serum levels of n-3PUFAs were associated with a lower prevalence of CAD and an increase in serum apolipoprotein A-1 level, even in an urban area...
  71. ncbi request reprint Effects of the T/L-type calcium channel blocker benidipine on albuminuria and plasma aldosterone concentration. A pilot study involving switching from L-type calcium channel blockers to benidipine
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital
    Int Heart J 55:519-25. 2014
    ..In addition, the high dose of benidipine reduced the PAC independent of BP control. These results suggest the T/L-type CCB benidipine may contribute to cardio-renal protection in addition to lowering BP. ..
  72. doi request reprint Association of n-3 polyunsaturated fatty acids with soluble thrombomodulin as a marker of endothelial damage: a cross-sectional pilot study
    Kenji Kawauchi
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Cardiol 64:312-7. 2014
    ..Furthermore, little is known about the association of EPA and DHA with sTM using the cross-sectional study method...
  73. doi request reprint Significance of imbalance in the ratio of serum n-3 to n-6 polyunsaturated fatty acids in patients with acute coronary syndrome
    Yuji Nishizaki
    Department of Cardiology, Juntendo University Graduate School of Medicine, Tokyo, Japan
    Am J Cardiol 113:441-5. 2014
    ..14, 95% confidence interval 1.16 to 8.49), but this was not true for DHA/AA. In conclusion, an imbalance in the ratio of serum EPA to AA, but not in the ratio of DHA to AA, was significantly associated with ACS...
  74. ncbi request reprint Neurological benefit of therapeutic hypothermia following return of spontaneous circulation for out-of-hospital non-shockable cardiac arrest
    Taketomo Soga
    Department of Cardiology, Cardiopulmonary Resuscitation and Emergency Cardiovascular Care, Surugadai Nihon University Hospital, Tokyo, Japan
    Circ J 76:2579-85. 2012
    ....
  75. doi request reprint Association between prehospital time interval and short-term outcome in acute heart failure patients
    Masashi Takahashi
    Tokyo CCU Network Scientific Committee, Tokyo, Japan
    J Card Fail 17:742-7. 2011
    ..However, the importance of early triage and treatment initiation in the setting of AHF has not been recognized...
  76. ncbi request reprint An early and complete reperfusion strategy for acute myocardial infarction using fibrinolysis and subsequent transluminal therapy--The FAST trial
    Ken Nagao
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 66:576-82. 2002
    ..TIMI-3 flow was achieved at an earlier stage with monteplase and this agent may be beneficial in the FAST therapy...
  77. ncbi request reprint [Review of arrythmias related to acute myocardial infarction and its treatment]
    Shingo Furuya
    Department of Internal Medicine II, Nihon University School of Medicine
    Nihon Rinsho 60:1427-33. 2002
    ..In this article, we reviewed that arrhythmias associated with AMI and strategy for treatments of complicated arrhythmias in the clinical settings...
  78. ncbi request reprint [Ischemic sudden heart arrest]
    Ken Nagao
    Nihon Naika Gakkai Zasshi 93:300-5. 2004
  79. ncbi request reprint [Reperfusion arrhythmia]
    Kazuhiro Watanabe
    Department of Cardiology, Nihon University, Surugadai Hospital
    Nippon Rinsho . 2007