Yoko Mochizuki

Summary

Affiliation: Nihon University School of Medicine
Country: Japan

Publications

  1. ncbi request reprint Creutzfeldt-Jakob disease with florid plaques after cadaveric dura mater graft
    Yoko Mochizuki
    Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Neuropathology 23:136-40. 2003
  2. ncbi request reprint Hereditary paroxysmal ataxia with mental retardation: a clinicopathological study in relation to episodic ataxia type 2
    Y Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, 2 6 1 Musashidai, Fuchu shi, 183 0042 Tokyo, Japan
    Acta Neuropathol 108:345-9. 2004
  3. ncbi request reprint Acute limbic encephalitis: a new entity?
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, 2 6 1 Musashidai, Fuchu shi, Tokyo 183 0042, Japan
    Neurosci Lett 394:5-8. 2006
  4. doi request reprint Familial ALS with FUS P525L mutation: two Japanese sisters with multiple systems involvement
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo 183 0042, Japan
    J Neurol Sci 323:85-92. 2012
  5. doi request reprint Supranuclear ophthalmoparesis and vacuolar degeneration of the cerebral white matter in amyotrophic lateral sclerosis: a clinicopathological study
    Takahiro Takeda
    Department of Neurology, Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan
    Amyotroph Lateral Scler 13:74-83. 2012
  6. ncbi request reprint [An autopsy case of corticobasal degeneration with notable early onset apraxia: a case report and literature review focused on apraxia]
    Taku Homma
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan
    Brain Nerve 65:887-93. 2013
  7. pmc Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V)
    Kentaro Hayashi
    Department of Neurology, Tokyo Metropolitan Neurological Hospital, 2 6 1 Musashidai, Fuchu shi, Tokyo, 183 0042, Japan
    Acta Neuropathol Commun 4:107. 2016
  8. doi request reprint ALS patients with ability to communicate after long-term mechanical ventilation have confined degeneration to the motor neuron system
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan Department of Neurology, Tokyo Metropolitan Kita Medical and Rehabilitation Center for the Disabled, Tokyo, Japan Electronic address
    J Neurol Sci 363:245-8. 2016
  9. doi request reprint Predictors of impaired communication in amyotrophic lateral sclerosis patients with tracheostomy-invasive ventilation
    Yuki Nakayama
    a Laboratory of Nursing Research for Intractable Disease, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
    Amyotroph Lateral Scler Frontotemporal Degener 17:38-46. 2015
  10. doi request reprint A Japanese patient with familial ALS and a p.K510M mutation in the gene for FUS (FUS) resulting in the totally locked-in state
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan Department of Neurology, Tokyo Metropolitan Kita Medical and Rehabilitation Centre for the Disabled, Tokyo, Japan
    Neuropathology 34:504-9. 2014

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Creutzfeldt-Jakob disease with florid plaques after cadaveric dura mater graft
    Yoko Mochizuki
    Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Neuropathology 23:136-40. 2003
    ..The electron-microscopic findings showed bundles of amyloid filaments which radiated from the center of the plaques without degenerating neurites. This case of D-CJD may belong to a new subtype of D-CJD...
  2. ncbi request reprint Hereditary paroxysmal ataxia with mental retardation: a clinicopathological study in relation to episodic ataxia type 2
    Y Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, 2 6 1 Musashidai, Fuchu shi, 183 0042 Tokyo, Japan
    Acta Neuropathol 108:345-9. 2004
    ..It is considered that the cerebellar cortical degeneration and the minor malformations found in the brain are closely related to one another, rather than having occurred independently...
  3. ncbi request reprint Acute limbic encephalitis: a new entity?
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, 2 6 1 Musashidai, Fuchu shi, Tokyo 183 0042, Japan
    Neurosci Lett 394:5-8. 2006
    ..HSV-1, -2 and human herpes virus-6 were negative immunohistochemically. We believe that our autopsy case may contribute to understanding the neuropathological background of non-herpetic acute limbic encephalitis...
  4. doi request reprint Familial ALS with FUS P525L mutation: two Japanese sisters with multiple systems involvement
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo 183 0042, Japan
    J Neurol Sci 323:85-92. 2012
    ....
  5. doi request reprint Supranuclear ophthalmoparesis and vacuolar degeneration of the cerebral white matter in amyotrophic lateral sclerosis: a clinicopathological study
    Takahiro Takeda
    Department of Neurology, Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan
    Amyotroph Lateral Scler 13:74-83. 2012
    ....
  6. ncbi request reprint [An autopsy case of corticobasal degeneration with notable early onset apraxia: a case report and literature review focused on apraxia]
    Taku Homma
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan
    Brain Nerve 65:887-93. 2013
    ..We believe the present case is valuable since very few reports have provided a detailed description of clinicopathological apraxia in association with CBD...
  7. pmc Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V)
    Kentaro Hayashi
    Department of Neurology, Tokyo Metropolitan Neurological Hospital, 2 6 1 Musashidai, Fuchu shi, Tokyo, 183 0042, Japan
    Acta Neuropathol Commun 4:107. 2016
    ..In conclusion, patients with ALS that had progressed to result in communication Stage V showed rapidly-progressed symptoms, and their common lesions could cause the manifestations of communication Stage V...
  8. doi request reprint ALS patients with ability to communicate after long-term mechanical ventilation have confined degeneration to the motor neuron system
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan Department of Neurology, Tokyo Metropolitan Kita Medical and Rehabilitation Center for the Disabled, Tokyo, Japan Electronic address
    J Neurol Sci 363:245-8. 2016
    ..To clarify the position in the amyotrophic lateral sclerosis (ALS) spectrum, of a subgroup of patients who maintained the ability to communicate after long-term mechanical ventilation (LTMV) by tracheostomy...
  9. doi request reprint Predictors of impaired communication in amyotrophic lateral sclerosis patients with tracheostomy-invasive ventilation
    Yuki Nakayama
    a Laboratory of Nursing Research for Intractable Disease, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
    Amyotroph Lateral Scler Frontotemporal Degener 17:38-46. 2015
    ..Rapid disease progression might indicate future communication impairment after the use of TIV. We highly recommend early detection of impaired communication and identification of the best methods of communication. ..
  10. doi request reprint A Japanese patient with familial ALS and a p.K510M mutation in the gene for FUS (FUS) resulting in the totally locked-in state
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan Department of Neurology, Tokyo Metropolitan Kita Medical and Rehabilitation Centre for the Disabled, Tokyo, Japan
    Neuropathology 34:504-9. 2014
    ..These features suggest that the morphological characteristics of the FUS-immunoreactive structures and distribution of the lesions vary with the diversity of mutations in FUS. ..
  11. doi request reprint Lateralized cortical involvement and contralateral parkinsonism without basal ganglia involvement in two autopsy cases of corticobasal syndrome-Alzheimer's disease
    Taku Homma
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan Department of Pathology, Ebara Hospital, Tokyo, Japan Department of Pathology, Saitama Medical University, Saitama, Japan
    J Alzheimers Dis 40:51-5. 2014
    ..Thus, nigrostriatial lesions and contralateral cerebral cortical lesions can cause motor disturbances in CBS, necessitating the need for bedside examination in patients with CBS. ..
  12. doi request reprint Novel G37V mutation of SOD1 gene in autopsied patient with familial amyotrophic lateral sclerosis
    Junpei Kobayashi
    Department of Neurology, Tokyo Metropolitan Neurological Hospital, Japan
    Amyotroph Lateral Scler 13:570-2. 2012
    ..His disease duration was 14 months, and he died of respiratory failure. The disease in this patient with the G37V mutation showed a rapid progression, although patients with G37R mutation are known to have a long survival...
  13. doi request reprint Frontotemporal lobar degeneration with writing disturbance mainly consisting of omission of kana letters
    Toshio Shimizu
    a Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan
    Neurocase 20:355-60. 2014
    ..The neurolinguistic analysis of our case suggests the disturbance of the moraic frame of words in the transcription process of morae into kana letters or kana-letter cards. ..
  14. doi request reprint Proportional neuronal loss between the primary motor and sensory cortex in amyotrophic lateral sclerosis
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan
    Neurosci Lett 503:73-5. 2011
    ..Moreover, the number of neurons in MI and SI was significantly correlated, suggesting that the neurons in both sites might be interdependent and might decrease proportionally...
  15. ncbi request reprint Memory deficits in amyotrophic lateral sclerosis patients with dementia and degeneration of the perforant pathway A clinicopathological study
    Takahiro Takeda
    Department of Neurology, Tokyo Metropolitan Institute for Neuroscience, 2 6 Musashi dai, Fuchu shi, 183 8526 Tokyo, Japan
    J Neurol Sci 260:225-30. 2007
    ..This involvement of the perforant pathway in ALS patients and its correlation to memory deficits should be taken in account for evaluation of dementia...
  16. doi request reprint Selective nuclear shrinkage of oligodendrocytes lacking glial cytoplasmic inclusions in multiple system atrophy: a 3-dimensional volumetric study
    Naoto Uyama
    Department of Neurology, Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan
    J Neuropathol Exp Neurol 68:1084-91. 2009
    ..This novel 3-dimensional strategy provides pivotal data that link GCI formation and degeneration in MSA...
  17. doi request reprint Frequent globular neuronal cytoplasmic inclusions in the medial temporal region as a possible characteristic feature in multiple system atrophy with dementia
    Taku Homma
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan
    Neuropathology 36:421-431. 2016
    ..We suggest that frequent G-NCIs in the medial temporal region, and particularly the subiculum, is one of the important pathological findings of MSA-D, even when a case with MSA-D reveals no significant cerebral atrophy...
  18. doi request reprint Medial temporal regional argyrophilic grain as a possible important factor affecting dementia in Parkinson's disease
    Taku Homma
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan
    Neuropathology 35:441-51. 2015
    ....
  19. ncbi request reprint [Neuropathological findings of non-herpetic limbic encephalitis]
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Fuchu shi, Tokyo, Japan
    Brain Nerve 62:861-8. 2010
    ..These findings are more similar to those in the case of autoimmune limbic encephalitis than those in the case of HSE. It is likely that these mild neuropathological changes in the case of NHLE are reflective of a good clinical outcome...
  20. ncbi request reprint [Degenerative disease (1), dementia, no. 7 in series of articles: basic knowledge of neuropathology for neurosurgeons]
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, 2 6 1 Musashidai, Fuchu shi, Tokyo 183 0042, Japan
    No Shinkei Geka 31:89-97. 2003
  21. doi request reprint Forme fruste or incipient form of widespread-type amyotrophic lateral sclerosis, or motor neuron disease with pallido-nigro-luysian atrophy? An autopsy case report
    Tomoyo Hashimoto
    Department of Neuropathology, Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan
    Neuropathology 28:309-16. 2008
    ..The neuropathological features of the present case appear to be important for understanding the nature of widespread-type ALS and MND with PNLA...
  22. doi request reprint The somatosensory cortex in multiple system atrophy
    Yoko Mochizuki
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, 2 6 1, Musashidai, Fuchu shi, Tokyo, 183 0042, Japan
    J Neurol Sci 271:174-9. 2008
    ..Therefore, the effects of MSA are apparently related to selective loss of the small-sized myelinated fibers in the corticospinal tract...
  23. doi request reprint Phosphorylated α-synuclein immunoreactivity in the posterior pituitary lobe
    Taku Homma
    Department of Pathology, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo Department of Pathology, Saitama Medical University, Iruma gun, Saitama, Japan
    Neuropathology 32:385-9. 2012
    ..1%) and sensitivity (88.5%), in both Parkinson's disease and dementia with Lewy bodies, suggesting that this finding can be a useful hallmark of Lewy body-related disorders...
  24. ncbi request reprint Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model
    Noriyuki Shibata
    Department of Pathology, Neurological Institute, Tokyo Women s Medical University, Tokyo, Japan
    Neuropathology 27:49-61. 2007
    ....
  25. ncbi request reprint [Clinical features and neuropathological findings of familial amyotrophic lateral sclerosis with an H43R mutation in Cu/Zn superoxide dismutase]
    Yoko Mochizuki
    Division of Neurology, Department of Medicine, Nihon University School of Medicine
    Rinsho Shinkeigaku 43:491-5. 2003
    ..The inclusions reacted with both anti-SOD1 and anti-ubiquitin antibodies. This is the first report of the neuropathological findings of FALS with this mutation...
  26. ncbi request reprint [An autopsy case of dementia with Lewy bodies which was clinically suspected to be Parkinson's disease complicated with Alzheimer-type dementia]
    Takao Shichi
    No To Shinkei 56:1058-68. 2004
  27. ncbi request reprint [An autopsy case of degenerative disease characterized by parkinsonism, dementia, and pathology with difficulty to be categorized]
    Fusako Yokochi
    No To Shinkei 55:813-21. 2003
  28. ncbi request reprint Silver stainings distinguish Lewy bodies and glial cytoplasmic inclusions: comparison between Gallyas-Braak and Campbell-Switzer methods
    Toshiki Uchihara
    Department of Neuropathology, Tokyo Metropolitan Institute for Neuroscience, 2 6 Musashi dai, Fuchu, 183 8526 Tokyo, Japan
    Acta Neuropathol 110:255-60. 2005
    ..Even though these empirical differences still remain to be explained, awareness of this clear distinction is potentially of diagnostic and pathological relevance...