Ayako Oyane

Summary

Affiliation: National Institute of Advanced Industrial Science and Technology
Country: Japan

Publications

  1. doi request reprint Preliminary in vivo study of apatite and laminin-apatite composite layers on polymeric percutaneous implants
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology, Central 4, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8562, Japan
    J Biomed Mater Res B Appl Biomater 97:96-104. 2011
  2. doi request reprint Controlled superficial assembly of DNA-amorphous calcium phosphate nanocomposite spheres for surface-mediated gene delivery
    Ayako Oyane
    Nanomaterials Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan Electronic address
    Colloids Surf B Biointerfaces 141:519-27. 2016
  3. pmc Formation of apatite coatings on an artificial ligament using a plasma- and precursor-assisted biomimetic process
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Ibaraki Prefectural University of Health Sciences, 4669 2 Ami Ami machi, Inashiki Gun, Ibaraki 300 0394, Japan
    Int J Mol Sci 14:19155-68. 2013
  4. doi request reprint Liquid-phase laser process for simple and area-specific calcium phosphate coating
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    J Biomed Mater Res A 100:2573-80. 2012
  5. doi request reprint Calcium phosphate composite layers for surface-mediated gene transfer
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    Acta Biomater 8:2034-46. 2012
  6. doi request reprint Fabrication of a DNA-lipid-apatite composite layer for efficient and area-specific gene transfer
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    J Mater Sci Mater Med 23:1011-9. 2012
  7. ncbi request reprint Bonelike apatite formation on ethylene-vinyl alcohol copolymer modified with silane coupling agent and calcium silicate solutions
    Ayako Oyane
    Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo ku, Kyoto 606 8501, Japan
    Biomaterials 24:1729-35. 2003
  8. doi request reprint Enhanced immobilization of acidic proteins in the apatite layer via electrostatic interactions in a supersaturated calcium phosphate solution
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology, Central 4, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8562, Japan
    Acta Biomater 7:2969-76. 2011
  9. doi request reprint Highly efficient gene transfer system using a laminin-DNA-apatite composite layer
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki, Japan
    J Gene Med 12:194-206. 2010
  10. doi request reprint Fibronectin-DNA-apatite composite layer for highly efficient and area-specific gene transfer
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    J Biomed Mater Res A 92:1038-47. 2010

Collaborators

Detail Information

Publications47

  1. doi request reprint Preliminary in vivo study of apatite and laminin-apatite composite layers on polymeric percutaneous implants
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology, Central 4, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8562, Japan
    J Biomed Mater Res B Appl Biomater 97:96-104. 2011
    ..Our coating process to form HA and laminin-HA composite layers would be useful in fabricating polymeric percutaneous devices with a reduced risk of bacterial infection, although further in vivo studies are required...
  2. doi request reprint Controlled superficial assembly of DNA-amorphous calcium phosphate nanocomposite spheres for surface-mediated gene delivery
    Ayako Oyane
    Nanomaterials Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan Electronic address
    Colloids Surf B Biointerfaces 141:519-27. 2016
    ..As demonstrated herein, controlling the coprecipitation conditions is important for designing a cell-stimulating and biocompatible scaffold surface consisting of an assembly of DNA-ACP nanocomposite spheres. ..
  3. pmc Formation of apatite coatings on an artificial ligament using a plasma- and precursor-assisted biomimetic process
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Ibaraki Prefectural University of Health Sciences, 4669 2 Ami Ami machi, Inashiki Gun, Ibaraki 300 0394, Japan
    Int J Mol Sci 14:19155-68. 2013
    ..The resulting apatite-coated artificial ligament should exhibit improved osseointegration within the bone tunnel and possesses great potential for use in ligament reconstructions...
  4. doi request reprint Liquid-phase laser process for simple and area-specific calcium phosphate coating
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    J Biomed Mater Res A 100:2573-80. 2012
    ..Furthermore, the present process is carried out under mild conditions, that is, at normal pressures and temperatures in a safe aqueous medium. These are significant advantages of the proposed CaP coating technique...
  5. doi request reprint Calcium phosphate composite layers for surface-mediated gene transfer
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    Acta Biomater 8:2034-46. 2012
    ..These composite layers, given their good biocompatibility and the potential to control cell behavior on their surfaces, have great potential in tissue engineering applications...
  6. doi request reprint Fabrication of a DNA-lipid-apatite composite layer for efficient and area-specific gene transfer
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    J Mater Sci Mater Med 23:1011-9. 2012
    ..The present gene transfer system using the PD-derived DLp-Ap layer, with the advantages of high efficiency in the presence of serum and area-specificity, would be useful in tissue engineering...
  7. ncbi request reprint Bonelike apatite formation on ethylene-vinyl alcohol copolymer modified with silane coupling agent and calcium silicate solutions
    Ayako Oyane
    Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo ku, Kyoto 606 8501, Japan
    Biomaterials 24:1729-35. 2003
    ..Hence, it has great potential as a bone substitute...
  8. doi request reprint Enhanced immobilization of acidic proteins in the apatite layer via electrostatic interactions in a supersaturated calcium phosphate solution
    Ayako Oyane
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology, Central 4, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8562, Japan
    Acta Biomater 7:2969-76. 2011
    ..Thus, the use of acidic rather than basic proteins improves the immobilization efficiency in the present coating process...
  9. doi request reprint Highly efficient gene transfer system using a laminin-DNA-apatite composite layer
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki, Japan
    J Gene Med 12:194-206. 2010
    ....
  10. doi request reprint Fibronectin-DNA-apatite composite layer for highly efficient and area-specific gene transfer
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    J Biomed Mater Res A 92:1038-47. 2010
    ....
  11. doi request reprint Reduction of surface roughness of a laminin-apatite composite coating via inhibitory effect of magnesium ions on apatite crystal growth
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 4, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8562, Japan
    Acta Biomater 4:1342-8. 2008
    ....
  12. ncbi request reprint Novel gene-transferring scaffolds having a cell adhesion molecule-DNA-apatite nanocomposite surface
    A Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Gene Ther 14:1750-3. 2007
    ..Hence, the LD-Ap surface, which enhances cell attachment on its surface, and mediates a safe, highly efficient and controllable gene transfer, is highly applicable to tissue engineering and gene therapy applications...
  13. ncbi request reprint Simple surface modification of poly(epsilon-caprolactone) for apatite deposition from simulated body fluid
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, 2 41 6, Aomi, Koto ku, Tokyo135 0064, Japan
    Biomaterials 26:2407-13. 2005
    ..The surface-modified material successfully formed a dense and uniform bone-like surface apatite layer after incubation for 24 h in simulated body fluid with ion concentrations approximately equal to those of human blood plasma...
  14. ncbi request reprint Laminin-apatite composite coating to enhance cell adhesion to ethylene-vinyl alcohol copolymer
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan
    J Biomed Mater Res A 72:168-74. 2005
    ..Therefore, this type of composite material consisting of a synthetic polymer, apatite, and laminin has great potential as a skin terminal, with improved adhesiveness to skin tissue, as well as good biocompatibility...
  15. ncbi request reprint Spontaneous growth of a laminin-apatite nano-composite in a metastable calcium phosphate solution
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan
    Biomaterials 27:167-75. 2006
    ..Because of this nano-composite structure, a large number of laminin molecules were stably immobilized on the EVOH plate. This may be responsible for the excellent cell adhesion properties of this type of composite material...
  16. ncbi request reprint Simple surface modification of poly(epsilon-caprolactone) to induce its apatite-forming ability
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki, 305 8565, Japan
    J Biomed Mater Res A 75:138-45. 2005
    ..Therefore, this type of composite material will be a useful scaffold for bone tissue engineering...
  17. ncbi request reprint The formation of an antibacterial agent-apatite composite coating on a polymer surface using a metastable calcium phosphate solution
    Ayako Oyane
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan
    Biomaterials 27:3295-303. 2006
    ..The composites investigated in this study showed antibacterial activity against Escherichia coli and Staphylococcus aureus, and would be useful as materials in percutaneous devices having antibacterial activity and good biocompatibility...
  18. pmc BMP-2 gene-fibronectin-apatite composite layer enhances bone formation
    Wei Zhang
    Nanosystem Research Institute NRI, National Institute of Advanced Industrial Science and Technology AIST, Higashi 1 1 1, Tsukuba, Ibaraki 305 8565, Japan
    J Biomed Sci 18:62. 2011
    ..We have developed an apatite composite layer including the bone morphogenetic protein-2 (BMP-2) gene and fibronectin (FB), and we evaluated its ability to induce bone formation...
  19. doi request reprint Enhanced wound healing associated with Sharpey's fiber-like tissue formation around FGF-2-apatite composite layers on percutaneous titanium screws in rabbits
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Ibaraki Prefectural University of Health Sciences, 4669 2 Ami, Ami Machi, Inashiki Gun, Ibaraki 300 0394, Japan
    Arch Orthop Trauma Surg 132:113-21. 2012
    ..The purpose of this study was to elucidate the mechanism of the improvement in infection resistance associated with FGF-2-apatite composite layers...
  20. doi request reprint A new approach for hydroxyapatite coating on polymeric materials using laser-induced precursor formation and subsequent aging
    Baek Hee Lee
    Nanoarchitectonics Research Center NARC, National Institute of Advanced Industrial Science and Technology AIST, Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan
    ACS Appl Mater Interfaces 1:1520-4. 2009
    ..The resulting HAP film coated on EVOH demonstrated excellent structural and chemical uniformity and cell adhesion with the CHO-K1 and BHK-21 cells. This process provides a practical technique for coating HAP onto polymeric materials...
  21. ncbi request reprint Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating
    Yoshiro Yokoyama
    Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 4, 1 1 1, Higashi, Tsukuba shi, Ibaraki, Japan
    J Mater Sci Mater Med 18:1727-34. 2007
    ..The resultant bonelike apatite-PLLA composite would be useful as a scaffold for bone tissue regeneration...
  22. doi request reprint Zinc-containing apatite layers on external fixation rods promoting cell activity
    Xiupeng Wang
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Acta Biomater 6:962-8. 2010
    ..The Ti external fixation rods coated with zinc-containing apatite layers are expected to be more effective in accelerating the tissue regeneration around the surgical site than those coated with an apatite layer...
  23. doi request reprint Formation of an ascorbate-apatite composite layer on titanium
    Atsuo Ito
    National Institute of Advanced Industrial Science and Technology AIST, Institute for Human Science and Biomedical Engineering, Central 6, Higashi 1 1 1, Tsukuba, Ibaraki 305 8566, Japan
    Biomed Mater 2:S181-5. 2007
    ....
  24. doi request reprint BMP-2 and ALP gene expression induced by a BMP-2 gene-fibronectin-apatite composite layer
    Xiupeng Wang
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Biomed Mater 6:045004. 2011
    ..Although these results suggest the possibility of ectopic bone formation induced by the present gene delivery system, further study is necessary to prove this...
  25. doi request reprint Ascorbate-apatite composite and ascorbate-FGF-2-apatite composite layers formed on external fixation rods and their effects on cell activity in vitro
    Xiupeng Wang
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Acta Biomater 5:2647-56. 2009
    ..On the other hand, the AsMg-apatite composite layer should be precipitated at the part attached to bone tissue...
  26. doi request reprint Formation of a FGF-2 and calcium phosphate composite layer on a hydroxyapatite ceramic for promoting bone formation
    Yu Sogo
    National Institute of Advanced Industrial Science and Technology AIST, Institute for Human Science and Biomedical Engineering, Central 6, 1 1 1, Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Biomed Mater 2:S175-80. 2007
    ..Therefore, the FGF-2-immobilized HAP ceramic is expected to be a useful material for promoting new bone formation...
  27. doi request reprint Fibronectin-calcium phosphate composite layer on hydroxyapatite to enhance adhesion, cell spread and osteogenic differentiation of human mesenchymal stem cells in vitro
    Yu Sogo
    National Institute of Advanced Industrial Science and Technology, Institute for Human Science and Biomedical Engineering, Central 6, 1 1 1, Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Biomed Mater 2:116-23. 2007
    ..Therefore, the Fn-calcium phosphate composite layer formed on the HAP is useful for the enhancement of the spreading and osteogenic differentiation of hMSCs in vitro...
  28. doi request reprint Fibroblast growth factor-2-apatite composite layers on titanium screw to reduce pin tract infection rate
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki 305 8575, Japan
    J Biomed Mater Res B Appl Biomater 86:365-74. 2008
    ..056 Nm and 93.8% for those without the composite layer. Therefore, titanium screws with the FGF-2-apatite composite layer are useful for improving bone-screw interface strength and infection resistance in external skeletal fixation...
  29. doi request reprint Osteoblast differentiation and disinfection induced by nitrogen plasma-treated surfaces
    Wei Zhang
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    Biomed Mater Eng 21:75-82. 2011
    ..Moreover, the N₂ PIII-treated polymer surface has the ability to enhance differentiation of osteoblasts. N₂ PIII-treated polymer surface may therefore be useful in bone tissue engineering...
  30. pmc Improved bonding of partially osteomyelitic bone to titanium pins owing to biomimetic coating of apatite
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Ibaraki Prefectural University of Health Sciences, 4669 2 Ami Ami machi, Inashiki Gun, Ibaraki 300 0394, Japan
    Int J Mol Sci 14:24366-79. 2013
    ..These results suggest that the Ap layer formed by the room temperature process could effectively improve the fixation strength of the Ti pin for external fixation clinically even with partial osteomyelitis present...
  31. ncbi request reprint Calcium phosphate coating formed in infusion fluid mixture to enhance fixation strength of titanium screws
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki, Japan
    J Mater Sci Mater Med 18:1799-808. 2007
    ..The coating technique with the use of the infusion fluids is an effective method of improving bone-screw interface strength...
  32. ncbi request reprint Preparation of a bonelike apatite-polymer fiber composite using a simple biomimetic process
    Yoshiro Yokoyama
    National Institute of Advanced Industrial Science and Technology, Nanotechnology Research Institute, Central 4, 1 1 1 Higashi, Tsukuba shi, Ibaraki 305 8562, Japan
    J Biomed Mater Res B Appl Biomater 86:341-52. 2008
    ..Hence, the present surface modification and coating process would be a promising route to obtain new implant materials with bonelike mechanical properties and osteoconductivity...
  33. doi request reprint Silicate-apatite composite layers on external fixation rods and in vitro evaluation using fibroblast and osteoblast
    Xiupeng Wang
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    J Biomed Mater Res A 92:1181-9. 2010
    ....
  34. doi request reprint Dissolution rate of zinc-containing beta-tricalcium phosphate ceramics
    Atsuo Ito
    National Institute of Advanced Industrial Science and Technology, Institute for Human Science and Biomedical Engineering, Central 6, 1 1 1, Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Biomed Mater 1:134-9. 2006
    ....
  35. doi request reprint Enhanced bone formation using hydroxyapatite ceramic coated with fibroblast growth factor-2
    Hideo Tsurushima
    Department of Neurosurgery, Clinical Medicine, Tsukuba University, Tsukuba, Ibaraki, Japan
    Acta Biomater 6:2751-9. 2010
    ..A specific FGF-2 concentration may be needed for bone formation, and our system can release FGF-2 at adequate concentrations to induce bone formation...
  36. ncbi request reprint Formation and growth of clusters in conventional and new kinds of simulated body fluids
    Ayako Oyane
    Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo ku, Kyoto 606 8501, Japan
    J Biomed Mater Res A 64:339-48. 2003
    ..The m-SBF is recommended for the assessment of bioactivity of artificial materials as well as the formation of bonelike apatite on various substrates from the viewpoint of stability as well as similarity to blood plasma...
  37. ncbi request reprint Reduced platelet adhesion to titanium metal coated with apatite, albumin-apatite composite or laminin-apatite composite
    Masaki Uchida
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Central 6, Tsukuba, Ibaraki, Japan
    Biomaterials 26:6924-31. 2005
    ..These findings suggest that HA-Ti, AA-Ti and LA-Ti, especially AA-Ti and LA-Ti, would exhibit thromboresistance that is superior to commercially pure titanium metal in terms of platelet adhesion...
  38. pmc Fabrication of DNA-antibody-apatite composite layers for cell-targeted gene transfer
    Yushin Yazaki
    Research Institute for Science and Engineering, Waseda University, 3 4 1 Ohkubo, Shinjuku, Tokyo, 169 8555, Japan Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 4, 1 1 1 Higashi, Tsukuba, Ibaraki, 305 8562, Japan
    Sci Technol Adv Mater 13:064204. 2012
    ..These results suggest that the DA-Ap layer works as a mediator in a specific cell-targeted gene transfer system...
  39. doi request reprint Improved gene transfer efficiency of a DNA-lipid-apatite composite layer by controlling the layer molecular composition
    Yushin Yazaki
    Research Institute for Science and Engineering, Waseda University, 3 4 1 Ohkubo, Shinjuku, Tokyo 169 8555, Japan Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 4, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8562, Japan
    Colloids Surf B Biointerfaces 122:465-71. 2014
    ..These findings will serve as a useful design guide for the preparation of DLp-Ap layers with high gene transfer efficiency. ..
  40. doi request reprint Angiogenesis therapy for brain infarction using a slow-releasing drug delivery system for fibroblast growth factor 2
    Yoshiro Ito
    Department of Neurosurgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tennnoudai 1 1 1, Tsukuba, Ibaraki 305 8575, Japan
    Biochem Biophys Res Commun 432:182-7. 2013
    ..Moreover, fluorescence immunohistochemistry showed that released FGF2 influenced microglia cells. This new FGF2 DDS involving an FGF2 apatite coating can prevent infarction of the penumbra through the multipotential effects of FGF2...
  41. doi request reprint DNA-lipid-apatite composite layers enhance gene expression of mesenchymal stem cells
    Xiupeng Wang
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Mater Sci Eng C Mater Biol Appl 33:512-8. 2013
    ..The present gene transfer system using the DLp-Ap layers, with the advantages of good biocompatibility, bone-bonding ability, and efficacy in in vitro and in vivo gene transfer to MSCs, would be useful in bone tissue engineering...
  42. doi request reprint Signal molecules-calcium phosphate coprecipitation and its biomedical application as a functional coating
    Xiupeng Wang
    Human Technology Research Institute, Higashi, Tsukuba, Ibaraki, Japan
    Biofabrication 3:022001. 2011
    ..For this purpose, the presently existing coprecipitation methods and strategies on biomedical application are summarized and discussed...
  43. ncbi request reprint Preparation and assessment of revised simulated body fluids
    Ayako Oyane
    Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo ku, Kyoto 606 8501, Japan
    J Biomed Mater Res A 65:188-95. 2003
    ..The m-SBF is optimal for in vitro bioactivity assessment of artificial materials and for biomimetic production of bone-like apatite...
  44. doi request reprint Laser-assisted one-pot fabrication of calcium phosphate-based submicrospheres with internally crystallized magnetite nanoparticles through chemical precipitation
    Maki Nakamura
    Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8562, Japan
    Phys Chem Chem Phys 17:8836-42. 2015
    ..The present process and the resulting CaP-based spheres are expected to have great potential for biomedical applications. ..
  45. pmc The calcium phosphate matrix of FGF-2-apatite composite layers contributes to their biological effects
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Ibaraki Prefectural University of Health Sciences, 4669 2 Ami Ami machi, Inashiki Gun, Ibaraki 300 0394, Japan
    Int J Mol Sci 15:10252-70. 2014
    ..These results suggest that the chemistry of the calcium phosphate matrix that embeds FGF-2, in addition to FGF-2 content and activity, has a significant impact on composite infection resistance and fixation strength...
  46. ncbi request reprint Correction: mutsuzaki, h., et Al. Improved bonding of partially osteomyelitic bone to titanium pins owing to biomimetic coating of apatite. Int. J. Mol. Sci. 2013, 14, 24366-24379
    Hirotaka Mutsuzaki
    Department of Orthopaedic Surgery, Ibaraki Prefectural University of Health Sciences, 4669 2 Ami Ami machi, Inashiki Gun, Ibaraki 300 0394, Japan
    Int J Mol Sci 15:9789-92. 2014
    ..Several corrections are thus required in the abstract, the main text, the figure legends, and the figures (Table 1). The authors would like to apologize for any inconvenience this may have caused to readers of the journal. [...]. ..
  47. doi request reprint Physicochemical fabrication of antibacterial calcium phosphate submicrospheres with dispersed silver nanoparticles via coprecipitation and photoreduction under laser irradiation
    Maki Nakamura
    Nanomaterials Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Central 5, 1 1 1, Higashi, Tsukuba, Ibaraki 305 8565, Japan Electronic address
    Acta Biomater 46:299-307. 2016
    ..The present process and resulting antibacterial CaP-based submicrospheres are expected to be useful in dental healthcare and infection control...