T Nakamura

Summary

Affiliation: National Institute of Agrobiological Sciences
Country: Japan

Publications

  1. pmc Characterization of a granule-bound starch synthase isoform found in the pericarp of wheat
    T Nakamura
    Tohoku National Agriculture Experimental Station, Akahira 4, Morioka 020 01, Japan
    Plant Physiol 118:451-9. 1998
  2. ncbi Rapid classification of partial waxy wheats using PCR-based markers
    T Nakamura
    Department of Plant Breeding, Tohoku National Agriculture Research Center, Akahira 4, Morioka 020 0198, Iwate, Japan
    Genome 45:1150-6. 2002
  3. ncbi Two point mutations identified in emmer wheat generate null Wx-A1 alleles
    M Saito
    Department of Crop Breeding, Tohoku National Agriculture Research Center, 4 Akahira, Shimo kuriyagawa, Morioka, 020 0198, Iwate, Japan
    Theor Appl Genet 110:276-82. 2005
  4. ncbi A candidate autonomous version of the wheat MITE Hikkoshi is present in the rice genome
    M Saito
    Department of Crop Breeding, Tohoku National Agriculture Research Center, 4 Akahira, Shimo kuriyagawa, Morioka, Iwate, 020 0198, Japan
    Mol Genet Genomics 273:404-14. 2005
  5. ncbi Molecular comparison of waxy null alleles in common wheat and identification of a unique null allele
    M Saito
    Department of Crop Breeding, Tohoku National Agriculture Research Center, 4 Akahira, Shimo kuriyagawa, 020 0198 Morioka, Iwate, Japan
    Theor Appl Genet 108:1205-11. 2004
  6. ncbi Mutations in wheat starch synthase II genes and PCR-based selection of a SGP-1 null line
    T Shimbata
    Central Laboratory, Nippon Flour Mills Co Ltd, 5 1 3 Midorigaoka, Atsugi, Kanagawa, Japan
    Theor Appl Genet 111:1072-9. 2005
  7. pmc Upregulation of Reg 1alpha and GW112 in the epithelium of inflamed colonic mucosa
    S Shinozaki
    Institute of Gastroenterology, Tokyo Women s Medical University, Tokyo, Japan
    Gut 48:623-9. 2001
  8. pmc The Schizosaccharomyces pombe spo20(+) gene encoding a homologue of Saccharomyces cerevisiae Sec14 plays an important role in forespore membrane formation
    Y Nakase
    Department of Biology, Graduate School of Science, Osaka City University, Sumiyoshi ku, Osaka 558 8585, Japan
    Mol Biol Cell 12:901-17. 2001
  9. ncbi The molecular characterization and in situ expression pattern of pea SCARECROW gene
    N Sassa
    Laboratory of Plant Physiology, Faculty of Science, Japan Women's University, 2-8-1 Mejiro-dai, Bunkyo-ku, Tokyo, 112-8681 Japan
    Plant Cell Physiol 42:385-94. 2001
  10. ncbi Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha
    T Sumi
    Division of Molecular Regenerative Medicine, Course of Advanced Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    J Biol Chem 276:23092-6. 2001

Collaborators

Detail Information

Publications63

  1. pmc Characterization of a granule-bound starch synthase isoform found in the pericarp of wheat
    T Nakamura
    Tohoku National Agriculture Experimental Station, Akahira 4, Morioka 020 01, Japan
    Plant Physiol 118:451-9. 1998
    ..This study indicates that GBSSI and GBSSII are expressed in a tissue-specific manner in different organs, with GBSSII having an important function in amylose synthesis in the pericarp...
  2. ncbi Rapid classification of partial waxy wheats using PCR-based markers
    T Nakamura
    Department of Plant Breeding, Tohoku National Agriculture Research Center, Akahira 4, Morioka 020 0198, Iwate, Japan
    Genome 45:1150-6. 2002
    ..The PCR selection method described here is an easy and effective alternative to the commonly used SDS-PAGE methods for identification of null alleles...
  3. ncbi Two point mutations identified in emmer wheat generate null Wx-A1 alleles
    M Saito
    Department of Crop Breeding, Tohoku National Agriculture Research Center, 4 Akahira, Shimo kuriyagawa, Morioka, 020 0198, Iwate, Japan
    Theor Appl Genet 110:276-82. 2005
    ..The two mutations described here arose independently, and are not related to either of the Wx-A1 mutations identified in common wheat...
  4. ncbi A candidate autonomous version of the wheat MITE Hikkoshi is present in the rice genome
    M Saito
    Department of Crop Breeding, Tohoku National Agriculture Research Center, 4 Akahira, Shimo kuriyagawa, Morioka, Iwate, 020 0198, Japan
    Mol Genet Genomics 273:404-14. 2005
    ..The sequence information from the TPase of OsHikkoshi will thus be useful in isolating the autonomous element of the Hikkoshi system from wheat...
  5. ncbi Molecular comparison of waxy null alleles in common wheat and identification of a unique null allele
    M Saito
    Department of Crop Breeding, Tohoku National Agriculture Research Center, 4 Akahira, Shimo kuriyagawa, 020 0198 Morioka, Iwate, Japan
    Theor Appl Genet 108:1205-11. 2004
    ..Hence, the Turkey null Wx-A1 mutation was likely caused by the movement of a transposon, and this spontaneous mutation appears to be present in a limited geographical area...
  6. ncbi Mutations in wheat starch synthase II genes and PCR-based selection of a SGP-1 null line
    T Shimbata
    Central Laboratory, Nippon Flour Mills Co Ltd, 5 1 3 Midorigaoka, Atsugi, Kanagawa, Japan
    Theor Appl Genet 111:1072-9. 2005
    ..These markers will also be useful in breeding programs aimed at obtaining partial mutants missing one or two SGP-1 proteins...
  7. pmc Upregulation of Reg 1alpha and GW112 in the epithelium of inflamed colonic mucosa
    S Shinozaki
    Institute of Gastroenterology, Tokyo Women s Medical University, Tokyo, Japan
    Gut 48:623-9. 2001
    ..The aim of our study was to detect genes that are preferentially expressed in inflamed colonic epithelia and clarify the biochemical responses of epithelial cells in inflamed colonic mucosa...
  8. pmc The Schizosaccharomyces pombe spo20(+) gene encoding a homologue of Saccharomyces cerevisiae Sec14 plays an important role in forespore membrane formation
    Y Nakase
    Department of Biology, Graduate School of Science, Osaka City University, Sumiyoshi ku, Osaka 558 8585, Japan
    Mol Biol Cell 12:901-17. 2001
    ..Our results indicate that Spo20 regulates the formation of specialized membrane structures in addition to its recognized role in regulating Golgi secretory function...
  9. ncbi The molecular characterization and in situ expression pattern of pea SCARECROW gene
    N Sassa
    Laboratory of Plant Physiology, Faculty of Science, Japan Women's University, 2-8-1 Mejiro-dai, Bunkyo-ku, Tokyo, 112-8681 Japan
    Plant Cell Physiol 42:385-94. 2001
    ..The expression patterns were similar to those reported for A. thaliana and Zea mays, suggesting that SCR may be functionally conserved among plants and involved in the differentiation of the endodermis...
  10. ncbi Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha
    T Sumi
    Division of Molecular Regenerative Medicine, Course of Advanced Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    J Biol Chem 276:23092-6. 2001
    ..These results indicate that MRCKalpha phosphorylates and activates LIM kinases downstream of Cdc42, which in turn regulates the actin cytoskeletal reorganization through the phosphorylation and inactivation of ADF/cofilin...
  11. ncbi Mutational analysis of the PTEN gene in endometrial carcinoma and hyperplasia
    H Sun
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, Osaka, Japan
    Am J Clin Pathol 115:32-8. 2001
    ..The presence of PTEN mutations in hyperplasia suggests that PTEN inactivation may occur as an initiating event in endometrial carcinogenesis and is involved in the development of cytologic atypia in hyperplasia...
  12. ncbi Characterization of the human nebulette gene: a polymorphism in an actin-binding motif is associated with nonfamilial idiopathic dilated cardiomyopathy
    T Arimura
    Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Japan
    Hum Genet 107:440-51. 2000
    ..92-20.29), while this association was not found in familial IDC patients (n=24). These observations suggest that the nebulette polymorphism in the actin-binding motif was a novel genetic marker of susceptibility to nonfamilial IDC...
  13. doi Alkaline treatments to render starch-based biodegradable polymers self-mineralizable
    I B Leonor
    3Bs Research Group, Department of Polymer Engineering, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    J Tissue Eng Regen Med 1:425-35. 2007
    ..These results suggest that this rather simple treatment is a good method for surface functionalization and subsequent mineral nucleation and growth on biodegradable polymeric surfaces to be used for bone-related applications...
  14. ncbi Chloroplast ribonucleoproteins function as a stabilizing factor of ribosome-free mRNAs in the stroma
    T Nakamura
    Center for Gene Research, Nagoya University, Nagoya 464 8601, Japan
    J Biol Chem 276:147-52. 2001
    ..When the five cpRNPs were supplemented in the depleted extract, full activity was restored. We propose that these cpRNPs act as stabilizing factors for nonribosome-bound mRNAs in the stroma...
  15. ncbi Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene
    T O Akama
    Glycobiology Program, The Burnham Institute, La Jolla, California, USA
    Nat Genet 26:237-41. 2000
    ..In situ hybridization analysis did not detect CHST6 transcripts in corneal epithelium in an MCD type II patient, suggesting that the mutations found in type II lead to loss of cornea-specific expression of CHST6...
  16. ncbi Plant mercaptopyruvate sulfurtransferases: molecular cloning, subcellular localization and enzymatic activities
    T Nakamura
    Research and Education Center for Genetic Information, Nara Institute of Science and Technology, Ikoma, Nara, Japan
    Eur J Biochem 267:5621-30. 2000
    ..However, the mutation had no effect on levels of iron-sulfur enzyme activities, suggesting that MST1 is not directly involved in iron-sulfur cluster assembly...
  17. ncbi Gelatino-lattice corneal dystrophy: clinical features and mutational analysis
    T Nakamura
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Am J Ophthalmol 129:665-6. 2000
    ..To report five unrelated Japanese individuals with "gelatino-lattice corneal dystrophy that clinically resembled, to some extent, gelatinous drop-like corneal dystrophy and lattice corneal dystrophy type 1...
  18. ncbi Identification of HGF-like protein as a novel neurotrophic factor for avian dorsal root ganglion sensory neurons
    H Funakoshi
    Division of Biochemistry, Osaka University Graduate School of Medicine, Osaka, 565-0871, Japan
    Biochem Biophys Res Commun 283:606-12. 2001
    ..Taken together, we propose that HLP may play an important role in chick sensory ganglia at relatively late stages of development. This is the first evidence that HLP functions as a neurotrophic factor...
  19. pmc Evidence in support of a four transmembrane-pore-transmembrane topology model for the Arabidopsis thaliana Na+/K+ translocating AtHKT1 protein, a member of the superfamily of K+ transporters
    Y Kato
    Graduate School of Bioagricultural Sciences and Bioscience Center, Nagoya University, Nagoya 464-8601, Japan
    Proc Natl Acad Sci U S A 98:6488-93. 2001
    ..Taken together, our results show that AtHKT1 contains eight transmembrane-spanning segments...
  20. ncbi Autocrine motility factor enhances hepatoma cell invasion across the basement membrane through activation of beta1 integrins
    T Torimura
    The Second Department of Medicine and Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume City, Japan
    Hepatology 34:62-71. 2001
    ..Our results indicate that AMF/PHI enhances hepatoma cell invasion through Matrigel in an autocrine manner by stimulating the adhesion, motility, and MMP-2 secretion of these cells through activation of beta1 integrins...
  21. doi Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus
    H Miyagawa
    Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812 8582, Japan
    Rheumatology (Oxford) 47:158-64. 2008
    ..Identification of the genes responsible for systemic lupus erythematosus (SLE)...
  22. ncbi Increased expression of CCAAT/enhancer binding protein-beta and -delta and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rats
    Y Sato
    Division of Endocrinology and Metabolism, Department of Medicine, Shiga University of Medical Science, Seta tsukinowa cho, Otsu, Shiga, 520 2192, Japan
    Diabetologia 50:481-9. 2007
    ....
  23. ncbi The squamous cell carcinoma antigens as relevant biomarkers of atopic dermatitis
    K Mitsuishi
    Department of Dermatology, Atopy Allergy Research Center, Juntendo University, Tokyo, Japan
    Clin Exp Allergy 35:1327-33. 2005
    ..We recently found that the squamous cell carcinoma antigens 1 (SCCA1) and SCCA2 are novel biomarkers of bronchial asthma, downstream of IL-4 and IL-13...
  24. ncbi Transcript profiling in plastid arginine tRNA-CCG gene knockout moss: construction of Physcomitrella patens plastid DNA microarray
    T Nakamura
    Center for Gene Research, Nagoya University, Nagoya 464 8602, Japan
    Plant Biol (Stuttg) 7:258-65. 2005
    ..Additionally, the plastid DNA microarray revealed that most plastid genes were expressed at similar levels in wild-type and transformant mosses. This indicates that trnR-CCG is not essential for the expression of plastid genes...
  25. ncbi DNA-binding activity of LndI protein and temporal expression of the gene that upregulates landomycin E production in Streptomyces globisporus 1912
    Yu Rebets
    Department of Genetics and Biotechnology of Ivan Franko National University of L viv, Grushevskogo st 4, L viv 79005, Ukraine
    Microbiology 151:281-90. 2005
    ..In solid-phase analysis, lndI expression was evident in substrate mycelia but was absent from aerial hyphae and spores...
  26. ncbi Association between catechol-O-methyltransferase gene polymorphisms and wearing-off and dyskinesia in Parkinson's disease
    M Watanabe
    Department of Neurology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan
    Neuropsychobiology 48:190-3. 2003
    ..030, odds ratio = 4.80) compared with controls, although these differences were not significant after Bonferroni's correction. Our results may help understand the mechanism that cause complications of levodopa therapy in PD patients...
  27. ncbi Novel LPL mutation (L303F) found in a patient associated with coronary artery disease and severe systemic atherosclerosis
    Y Saika
    Department of Internal Medicine and Molecular Science, Osaka University Graduate School of Medicine, Yamadaoka, Suita, Osaka, Japan
    Eur J Clin Invest 33:216-22. 2003
    ..In this paper, we report a 55-year-old type I hyperlipidaemic patient with a novel missense mutation in the LPL gene...
  28. ncbi Glucose-6-phosphatase gene mutations in 20 adult Japanese patients with glycogen storage disease type 1a with reference to hepatic tumors
    T Nakamura
    First Department of Pathology, Hamamatsu University School of Medicine, Shizuoka, Japan
    J Gastroenterol Hepatol 16:1402-8. 2001
    ..As most of the patients in our series are free from other chronic liver diseases such as viral hepatitis, other genetic and/or acquired factors may have influence on the sequel to this metabolic disease...
  29. ncbi Chromosome 13 locus, Pbd2, regulates bone density in mice
    M Shimizu
    Department of Orthopedic Surgery, Faculty of Medicine, Kyoto University, Japan
    J Bone Miner Res 16:1972-82. 2001
    ..These results confirmed the existence of a Pbd2 locus regulating bone density in the SAM strains...
  30. ncbi Acute parvovirus B19 infection during anti-retroviral therapy
    H Taguchi
    Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
    J Infect Chemother 7:110-2. 2001
    ..More than likely, highly active anti-retroviral therapy (HAART), including a protease inhibitor, played a role in clearing the virus...
  31. ncbi Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors
    K Yazawa
    Department of Surgery, Research Center on Aging and Adaptation, Shinshu University School of Medicine, Matsumoto, Japan
    Breast Cancer Res Treat 66:165-70. 2001
    ..This is the first demonstration that Bifidobacterium longum can be utilized as a specific gene delivery vector for gene therapy on solid breast tumors...
  32. ncbi Molecular cloning and characterization of a human homologue of TBPIP, a BRCA1 locus-related gene
    H Ijichi
    First Department of Anatomy, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka, Japan
    Gene 248:99-107. 2000
    ....
  33. pmc The Arabidopsis HKT1 gene homolog mediates inward Na(+) currents in xenopus laevis oocytes and Na(+) uptake in Saccharomyces cerevisiae
    N Uozumi
    BioScience Center, Nagoya University, Nagoya, 464 8601, Japan
    Plant Physiol 122:1249-59. 2000
    ..These data demonstrate that AtHKT1 differs in its transport properties from the wheat HKT1, and that AtHKT1 can mediate Na(+) and, to a small degree, K(+) transport in heterologous expression systems...
  34. ncbi Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes
    M Onno
    Laboratory of Cellular and Molecular Biology, Centre National de la Recherche Scientifique, Villejuif, France
    DNA Cell Biol 12:107-18. 1993
    ..The results are consistent with the possibility that TRE17 sequences other than oncTRE17 are translated if alternatively spliced. Expression of TRE17 in normal somatic cells was, however, not yet reported...
  35. ncbi Isolation and characterization of Xenopus follistatin and activins
    A Fukui
    Frontier Research Program, Institute of Physical and Chemical Research RIKEN, Saitama, Japan
    Dev Biol 159:131-9. 1993
    ..These results indicate that Xenopus XTC-F1 cells secrete several molecular forms of follistatin/activin-binding protein and three isoforms of activins AB and B in addition to activin A...
  36. ncbi Involvement of hepatocyte growth factor in kidney development
    O F Santos
    Harvard Medical School, Boston, Massachusetts 02115
    Dev Biol 163:525-9. 1994
    ..Perturbation of ureteric duct development as well as extraductal metanephric development was observed in embryonic kidneys incubated with the anti-HGF serum. Together, our data indicates an important role for HGF in kidney development...
  37. ncbi Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia
    Y Gu
    Jefferson Cancer Institute, Jefferson Cancer Center, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107
    Cancer Res 54:2327-30. 1994
    ..We conclude that while there is no specific sequence element present at all the breakpoints, the high density of Alu sequences in the breakpoint cluster region possibly makes the latter more prone to recombination events...
  38. pmc Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia
    R Prasad
    Jefferson Cancer Institute, Jefferson Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107
    Proc Natl Acad Sci U S A 91:8107-11. 1994
    ..In this model, the partner polypeptide plays an accessory role either by repressing activity of the truncated ALL-1 protein or by blocking the function of the normal protein presumably present in the leukemic cells...
  39. ncbi Tyrosine phosphorylation of MB-1, B29, and HS1 proteins in human B cells following receptor crosslinking
    D Hata
    Department of Pediatrics, Faculty of Medicine, Kyoto University, Japan
    Immunol Lett 40:65-71. 1994
    ..The results showed that HS1 may play an important role in signal transduction through sIgM and sIgD on human B cells...
  40. ncbi The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily
    C Biswas
    Department of Anatomy and Cellular Biology, Tufts University School of Medicine, Boston, Massachusetts 02111
    Cancer Res 55:434-9. 1995
    ....
  41. ncbi Enhanced expression of rat obese (ob) gene in adipose tissues of ventromedial hypothalamus (VMH)-lesioned rats
    T Funahashi
    Second Department of Internal Medicine, Osaka University, Medical School, Japan
    Biochem Biophys Res Commun 211:469-75. 1995
    ..These data suggest that ob gene might be up-regulated with fat accumulation even in non-genetically obese animals...
  42. ncbi Cyclin I: a new cyclin encoded by a gene isolated from human brain
    T Nakamura
    Biomedical R and D Department, Sumitomo Electric Industries, Yokohama, Japan
    Exp Cell Res 221:534-42. 1995
    ..The expression of cyclin I mRNA does not correlate directly to the cell cycle, and therefore cyclin I may be a novel cyclin member that functions independently of the cell cycle control...
  43. ncbi Inhibin alpha-subunit monomer is present in bovine follicular fluid
    K Sugino
    Frontier Research Program, RIKEN, Saitama, Japan
    Biochem Biophys Res Commun 159:1323-9. 1989
    ..In the in vitro rat pituitary assay, the 26 kDa alpha-subunit exhibited neither inhibin-like nor FSH-release stimulating activity...
  44. ncbi Purification and characterization of high molecular weight forms of inhibin from bovine follicular fluid
    K Sugino
    Frontier Research Program, Institute of Physical and Chemical Research RIKEN, Saitama, Japan
    Endocrinology 130:789-96. 1992
    ..On the basis of our findings, we propose that in bovine follicular fluid, the larger 105-kDa form of inhibin is processed successively to form the lowest molecular mass form, 32 kDa inhibin, through the smaller 95- and 55-kDa forms...
  45. ncbi Isolation and characterization of native activin B
    T Nakamura
    Frontier Research Program, Institute of Physical and Chemical Research RIKEN, Saitama, Japan
    J Biol Chem 267:16385-9. 1992
    ....
  46. ncbi Hepatocyte growth factor rapidly induces the tyrosine phosphorylation of 41-kDa and 43-kDa proteins in mouse keratinocytes
    Y Chatani
    Department of Biology, Gifu Pharmaceutical University, Japan
    Biochem Biophys Res Commun 185:860-6. 1992
    ..A possible role of the increased tyrosine phosphorylation of 41-kDa and 43-kDa protein in the signaling pathway of HGF is discussed...
  47. ncbi Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia
    T Nakamura
    Mammalian Genetics Laboratory, NCI Frederick Cancer Research and Development Center, Maryland 21702, USA
    Nat Genet 12:154-8. 1996
    ....
  48. ncbi Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin
    K Sugimoto
    Division of Biochemistry, Osaka University Medical School, Japan
    J Biol Chem 271:11548-56. 1996
    ..PB-cadherin may play an important role in morphogenesis and tissue formation in neural and non-neural cells for the development and maintenance of the brain and neuroendocrine organs by regulating cell-cell adhesion...
  49. ncbi cDNA cloning and expression of the Xenopus laevis vitellogenin receptor
    K Okabayashi
    Department of Life Science, University of Tokyo, Japan
    Biochem Biophys Res Commun 224:406-13. 1996
    ..6 kb in Xenopus ovary, weak but significant expression was observed in other tissues by RT-PCR analysis. The fact that major expression of the gene occurs in the ovary suggests that it has an important function in this organ...
  50. ncbi Characterization of cDNAs expressed in the early stages of microspore embryogenesis in barley (Hordeum vulgare) L
    P L Vrinten
    Tohoku National Agriculture Experimental Station, Iwate, Japan
    Plant Mol Biol 41:455-63. 1999
    ..The identification and characterization of the clones isolated in this study provides new information on the events involved in barley microspore embryogenesis...
  51. ncbi Four rice genes encoding cysteine synthase: isolation and differential responses to sulfur, nitrogen and light
    T Nakamura
    Nara Institute of Science and Technology, Research and Education Center for Genetic Information, Ikoma, Nara, Japan
    Gene 229:155-61. 1999
    ..These observations indicate that cysteine synthase genes encode functionally distinct cysteine synthase isoforms, and that they are coordinately regulated by the availability of sulfur, nitrogen, and light...
  52. ncbi Molecular cloning, characterization, and chromosomal localization of FKBP23, a novel FK506-binding protein with Ca2+-binding ability
    T Nakamura
    Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto, 606, Japan
    Genomics 54:89-98. 1998
    ..FKBP23 mRNA is expressed most strongly in heart, lung, and testis, beginning at day 8.5 of embryonic development. The FKBP23 gene was mapped to mouse chromosome 2...
  53. ncbi Cloning of the trkAH gene cluster and characterization of the Trk K(+)-uptake system of Vibrio alginolyticus
    T Nakamura
    Laboratory of Membrane Biochemistry, Faculty of Pharmaceutical Science, Chiba University, Japan
    Microbiology 144:2281-9. 1998
    ..Measurements of net K(+)-uptake rates indicated that the presence of these genes in E. coli renders the Trk systems independent of products from the E. coli sapABCDF (trkE) operon...
  54. ncbi Cut1 is loaded onto the spindle by binding to Cut2 and promotes anaphase spindle movement upon Cut2 proteolysis
    K Kumada
    Department of Biophysics, Graduate School of Science, Kyoto University, Japan
    Curr Biol 8:633-41. 1998
    ..Expression of Cut2 that cannot be degraded blocks sister chromatid separation and anaphase spindle elongation. Here, we have investigated the role of the Cut1-Cut2 interaction in sister chromatid separation...
  55. ncbi Identification of a novel type II activin receptor, type IIA-N, induced during the neural differentiation of murine P19 embryonal carcinoma cells
    H Shoji
    Institute for Enzyme Research, University of Tokushima, Japan
    Biochem Biophys Res Commun 246:320-4. 1998
    ..These results suggest that the expression of type IIA-N is specific to neural cells and mediates neural differentiation-specific activin signaling...
  56. ncbi Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome
    M Wada
    Department of Biochemistry, Kyushu University School of Medicine, Fukuoka 812 82, Japan
    Hum Mol Genet 7:203-7. 1998
    ..These results strongly implicate the cMOAT gene as responsible for the defects in DJS patients...
  57. pmc Isolation and chromosomal localization of a cornea-specific human keratin 12 gene and detection of four mutations in Meesmann corneal epithelial dystrophy
    K Nishida
    Department of Ophthalmology, Kyoto Prefectural University of Medicine, Japan
    Am J Hum Genet 61:1268-75. 1997
    ..Of particular interest, one of these mutations (Tyr429Asp), detected in both affected individuals in one of our pedigrees, is the first mutation to be identified within the alpha-helix-termination motif in type I keratin...
  58. ncbi Chromosomal localization of rat hepatocyte growth factor (Hgf) and HGF receptor (Met) and characterization of HGF receptor cDNA
    V R Wallenius
    Research Centre for Endocrinology and Metabolism RCEM, Department of Internal Medicine, Grona Straket 8, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Mamm Genome 8:661-7. 1997
    ..Therefore, the rat Hgf and HGF receptor/Met genes are located relatively close to each other, in a way similar to humans but not mice...
  59. ncbi Calumenin, a Ca2+-binding protein retained in the endoplasmic reticulum with a novel carboxyl-terminal sequence, HDEF
    D Yabe
    Department of Medical Chemistry, Faculty of Medicine, Kyoto University, Sakyo ku, Kyoto 606, Japan
    J Biol Chem 272:18232-9. 1997
    ..Calumenin is expressed most strongly in heart of adult and 18.5-day embryos. The calumenin gene (Calu) was mapped at the proximal portion of mouse chromosome 7...
  60. ncbi Molecular cloning of the Xenopus c-met/hepatocyte growth factor receptor and its regional expression during early development
    S Aoki
    Department of Oncology, Osaka University Medical School
    J Biochem 120:961-8. 1996
    ..Thus, c-Met is a highly conserved molecule in a wide range of species, as is its ligand, HGF. The HGF-Met system may be involved in early multiple organogenesis in Xenopus embryos...
  61. ncbi Purification and identification of a novel and four known serine proteinase inhibitors secreted by human glioblastoma cells
    N Koshikawa
    Division of Cell Biology, Yokohama City University
    J Biochem 119:334-9. 1996
    ..The secretion of multiple forms of serine proteinase inhibitors by human cancer cells raises the possibility that they might be involved in the abnormal growth of cancer cells...
  62. ncbi Cloning and expression of Xenopus HGF-like protein (HLP) and Ron/HLP receptor implicate their involvement in early neural development
    T Nakamura
    Department of Oncology, Osaka University Medical School, Japan
    Biochem Biophys Res Commun 224:564-73. 1996
    ..Thus, functional coupling between Ron receptor tyrosine kinase and HLP may have an important role in development of embryonic neural tissue in Xenopus laevis...
  63. ncbi Isolation and characterization of activin receptor from mouse embryonal carcinoma cells. Identification of its serine/threonine/tyrosine protein kinase activity
    T Nakamura
    Frontier Research Program, Institute of Physical and Chemical Research RIKEN, Saitama, Japan
    J Biol Chem 267:18924-8. 1992
    ..These results suggest that signal transduction of activin employs a novel pathway via a new class of cellular receptor in EC P19 cells...